LOCUS AF515447 4897 bp mRNA linear HUM 16-SEP-2002
DEFINITION Homo sapiens mesoderm induction early response 1 N2-beta mRNA,
complete cds, alternatively spliced.
ACCESSION AF515447
VERSION AF515447.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4897)
AUTHORS Paterno,G.D., Ding,Z., Lew,Y.Y., Nash,G.W., Mercer,F.C. and
Gillespie,L.L.
TITLE Genomic organization of the human mi-er1 gene and characterization
of alternatively spliced isoforms: regulated use of a facultative
intron determines subcellular localization
JOURNAL Gene 295 (1), 79-88 (2002)
PUBMED 12242014
REFERENCE 2 (bases 1 to 4897)
AUTHORS Paterno,G.D., Ding,Z., Yew,Y.Y., Nash,G.W., Mercer,F.C. and
Gillespie,L.L.
TITLE Direct Submission
JOURNAL Submitted (28-MAY-2002) Medicine, Memorial University, Health
Sciences Centre, St. John's, NF A1B 3V6, Canada
FEATURES Location/Qualifiers
source 1..4897
/db_xref="H-InvDB:HIT000081101"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p31.2"
CDS 234..1769
/note="transcription factor MI-ER1; alternatively spliced"
/codon_start=1
/product="mesoderm induction early response 1 N2-beta"
/protein_id="AAM76041.1"
/translation="MLPSVESSSPGGSATSDDHEFDPSADMLVHDFDDERTLEEEEMM
EGETNFSSEIEDLAREGDMPIHELLSLYGYGSTVRLPEEDEEEEEEEEEGEDDEDADN
DDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVASQDAQEIIRPRRCKYFDTNSE
VEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGICRYKENEKVYENDDQLLWDPEYL
PEDKVIIFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCNFDTEEALRRLRFN
VKAAREELSVWTEEECRNFEQGLKAYGKDFHLIQANKVRTRSVGECVAFYYMWKKSER
YDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESAASSRAPSPPPTASNSSNSQSEKE
DGTVSTANQNGVSSNGPGEILNKEEVKVEGLHINGPTGGNKKPLHADMDTNGYETDNL
TTDPKLAHMTARNENDFDEKSERPAKRRRVNSNGKESPGSSEFFQEAVSHGKFEELEN
TDD"
misc_feature 768..947
/note="Region: ELM2 domain"
misc_feature 1092..1223
/note="Region: SANT domain"
regulatory 4875..4880
/regulatory_class="polyA_signal_sequence"
BASE COUNT 1554 a 762 c 926 g 1655 t
ORIGIN
1 ctggaagaag gaggcgggcg gcccgggcct caggcccctc ccaggctctg agtctcccgg
61 ctgcaggcgg attggatggg gcttcttcag gcggtggcgg cagcagcgaa ggtggcggcg
121 gcagcagcgg cagcggctat ggtgtggtcg ctcgattctc ccagtgcctg gctgagtttc
181 ggacgtggtt aagaaccaac tggttgaggt tcaatgcaga caagacggat gtgatgctgc
241 catctgttga atcttcaagt ccaggaggtt cagcaacatc agatgaccat gaatttgatc
301 catcagctga catgctggtt catgattttg atgatgaacg aacattagaa gaggaagaaa
361 tgatggaagg agaaacaaac ttcagctctg aaatagaaga tcttgcaagg gaaggcgaca
421 tgccaattca tgaacttctc agcctttatg gttatggtag tactgttcga ctacctgaag
481 aagatgagga agaggaagaa gaggaagaag aaggtgaaga tgatgaagat gctgataatg
541 atgacaacag tggctgtagt ggggaaaata aagaggagaa tataaaggat tcatcaggtc
601 aggaggatga aactcagtct tccaatgatg atccatcaca atctgttgct tctcaagatg
661 cccaggaaat aatccgccca cgtcgatgta aatattttga tacaaatagt gaagtagaag
721 aagaatctga agaagatgaa gattatattc catcagaaga ctggaaaaag gagattatgg
781 tgggctccat gtttcaagca gaaattccag ttggcatttg tagatacaaa gaaaatgaaa
841 aagtatatga aaatgatgat cagctcctgt gggaccctga gtacttacca gaagataaag
901 tgattatatt tcttaaagat gcatctagaa gaacaggtga tgagaagggt gtagaagcaa
961 ttcctgaagg atctcacata aaagacaatg aacaggcttt atatgaattg gttaaatgca
1021 attttgatac agaagaagca ttgagaagat taagatttaa tgtaaaagca gctagagagg
1081 aattatctgt ttggacagag gaagagtgta gaaattttga acaagggctg aaggcctatg
1141 gaaaggattt tcatttgatt caggctaata aagtccgaac aaggtcagtt ggtgaatgtg
1201 tagcattcta ttacatgtgg aaaaaatctg aacgttatga tttctttgct cagcaaacac
1261 gatttggaaa gaagaaatat aatcttcatc ctggtgtaac ggattacatg gatcgtcttc
1321 tagacgaaag tgaaagtgct gcatctagtc gagcaccatc ccctccccca actgcatcaa
1381 acagtagtaa cagccagtct gagaaagaag atggcactgt aagcactgct aatcaaaatg
1441 gagtgtcatc taatggacca ggtgaaatat taaacaaaga ggaagtaaaa gttgaagggt
1501 tacacattaa tggaccaaca ggtggaaata agaaaccact tcatgcagat atggatacta
1561 atggttatga aacagataac cttaccactg acccaaaact tgcccatatg actgcaagaa
1621 atgaaaatga ttttgatgaa aaaagtgaga gacctgccaa aaggcgaagg gtaaacagca
1681 atggaaaaga aagtccaggt tcttctgaat ttttccaaga agcagtctca catgggaaat
1741 ttgaagaact tgaaaacaca gatgactaaa ttttagacct attttacttt ctttggagta
1801 aattctggtg tgactaaaat tttcagggtt gatgggttac cttaaaaagt tgatttcctt
1861 gaagcagttt gaaaatttga attgagtctt aactttagga aatgaggttt cataattctg
1921 ccttttgcag atttttttta ctttaaagct gtcagactct tttaagggta ttttaaaaat
1981 tagtaaattt gaatgaacta aagatatatc tctaccttct catttgaata tctttagttc
2041 attcagattt actaattttg gtaaatctga atgaactaaa gatgtatctg taccttctca
2101 tttgatgtat taatcataaa atttcactac aaggtaattt ttgcttagtt tgatggatga
2161 atgggaaact caagtccaaa tttctgctta ataccaattt ctctgagttt cttgaaatgt
2221 ctttaaaaca gacatttttc tcaccaaaca gtttgagtat ctttattaag gaaaccctta
2281 cgaatcctga aaattatgct agcatgattt ttttatatat agaagtttaa aaataaacca
2341 ggtcaggttt gtatatgtaa aattgttgac atcaatgatg tctttccata ttcttatctg
2401 ggcttaagaa atacattctg tatttttcca gattctttgt agcctttgaa agatttttac
2461 agtacatatg tcttgactga gctgtccttt cttaatacaa aagcgtgtat aattttctta
2521 acttgtacag ttggtaaact tttatgagag gaattgttat tctgagtctg tcagctttca
2581 ttttattttg ctaaggtttt tctaatgaat ttttaagtgt ttgtgtagta attaagtcat
2641 atttcttatc caggtggtta aagcattcat aaaggattat aaaatttttt tttttttttt
2701 tttaaatttc tacttaaggg caagtaattt gagaattctg aaattaagca tgatgcttag
2761 attgcagttt gttttgcatt tgctctaatt ttcaaaatta tttttgaagc aagacaaaag
2821 tttaatgtca gcttaagtgc ttaaatatat catgctgacc agaatcctgt tatttttata
2881 tgcatcataa aatttcccat ttctgcatta aataaacaga ggaggggggt caagtgatac
2941 ttagatattg gcacacacaa ggaacaactg ttggcaggca gtatcgattt tatgaagaga
3001 aagtgaagtt tgaaaacttt tcaaactttt ctagttacaa tccaattttt cagatttgat
3061 aatgcttttc caaagtgaaa ataagataca caataatcat tgctttttgt gattacagat
3121 aggattatcc atctgcatag ccttgtaaaa gtgccatttt atttttagtg ctaaattctt
3181 gttaaataat gtagttttat atagctgata gaccaaccta tatccaaact tttataaaat
3241 attaattatt cttgtttttc tcacacaggc atactccaaa tgcttcttcc agttcatttt
3301 tcagccatca gttcaagagc caatgccttt ttaaaataaa gcttctgtgg tcttgttttt
3361 aatggctcaa ctgtctgatg taattgagtg aaggtttgca ctgagaaatt agcattcagg
3421 ccttaccccc atgaagtatt actgttaaca tatgttcgga ctgcttccct tcaccaatgt
3481 gaacaacttt ttttcccaaa cagtattaaa agccactttg caacacttga cttcatctta
3541 atgtacattc actgttgtta catacatatc taagtaaatc aaagttttgg gtggaagtgt
3601 tgagaagtat gagttttttg ttgtttttgt tttacttaaa acttttaatt tatccagaat
3661 ggcagtagct ttagcaagca gatggtcaca atctgttttc taaatcattt tttattaaat
3721 gaatccaaag tatcctagct ctttgtcaaa gatggtctgt agaaatgttt ttaaagatta
3781 gggatgctgt actttttgaa ttgttgcagt gttggagatg ccattttcac ctttttaaaa
3841 agatgcattt tatttgcagg tttgtgaagt tcttgcaaac tcttactaca gaaatgtttt
3901 aaatacattc tcaggcatgt ttgcaaaaat atggcacatg tatacatttt aggaaatgtt
3961 acttttgtta atctttaaaa aatacaccta atgaaagaca ttccactatt atgcgtaatg
4021 ctcagctttt tgtaaagaaa tatttaattg tattttgtgt ttatacaggt atttcacaca
4081 ataatttgtt cttaatgcag ccactataac ttgataagtc attgcactat ttaaaaagtt
4141 ttagtaatat catgaattta atttgcttaa gatttagtac atttcagaac ttttgaactt
4201 ttgacaaatt gcattgggaa aagaagtctg ttaatagtga tttagtctcc ccgcctcatt
4261 cccaccccca acaaagcact atcattttca tttggaatgg gtatttttct gtttcatgat
4321 gtattttcaa atagagttca ggatctgcaa ttcagttcaa cacaagtttg ttgagcttta
4381 aaatgtattt gaagtaatat ttaaataggc atttaaaatt tcaaattaga tgttaaattt
4441 atgcatagta attttgcact gtaaaataat tcccttctcc cattccttgt ctgccattct
4501 gaatatgctt attaaaatat ttttttaaac atatttgcct acataatact gtgtgaatat
4561 tttcattaga ttaattcact aagattttat tagagattgt ttgaatgatg catgttattg
4621 acaaggcaaa tatatatata tacacagtct gtttcttcta ttcctagaca tattgcacta
4681 ctttttcagt ggttcttggt cccctttacc acatcttggg tgatgtattt ttgtcttctt
4741 cccctttgcc acaagagatc ctttcagtcc ctagacctcc attcactctg tttctcttct
4801 gctggattat ataatttaaa aataatgtgt tcccgtattt tgtagtggag ttcatatcac
4861 attatgtttt gcaaaataaa acttgttttg tcacaat
//