LOCUS AF515446 4816 bp mRNA linear HUM 16-SEP-2002
DEFINITION Homo sapiens mesoderm induction early response 1 N3-beta mRNA,
complete cds, alternatively spliced.
ACCESSION AF515446
VERSION AF515446.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4816)
AUTHORS Paterno,G.D., Ding,Z., Lew,Y.Y., Nash,G.W., Mercer,F.C. and
Gillespie,L.L.
TITLE Genomic organization of the human mi-er1 gene and characterization
of alternatively spliced isoforms: regulated use of a facultative
intron determines subcellular localization
JOURNAL Gene 295 (1), 79-88 (2002)
PUBMED 12242014
REFERENCE 2 (bases 1 to 4816)
AUTHORS Paterno,G.D., Ding,Z., Yew,Y.Y., Nash,G.W., Mercer,F.C. and
Gillespie,L.L.
TITLE Direct Submission
JOURNAL Submitted (28-MAY-2002) Medicine, Memorial University, Health
Sciences Centre, St. John's, NF A1B 3V6, Canada
FEATURES Location/Qualifiers
source 1..4816
/db_xref="H-InvDB:HIT000081100"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p31.2"
CDS 150..1688
/note="transcription factor MI-ER1; alternatively spliced"
/codon_start=1
/product="mesoderm induction early response 1 N3-beta"
/protein_id="AAM76040.1"
/translation="MAEPSVESSSPGGSATSDDHEFDPSADMLVHDFDDERTLEEEEM
MEGETNFSSEIEDLAREGDMPIHELLSLYGYGSTVRLPEEDEEEEEEEEEGEDDEDAD
NDDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVASQDAQEIIRPRRCKYFDTNS
EVEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGICRYKENEKVYENDDQLLWDPEY
LPEDKVIIFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCNFDTEEALRRLRF
NVKAAREELSVWTEEECRNFEQGLKAYGKDFHLIQANKVRTRSVGECVAFYYMWKKSE
RYDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESAASSRAPSPPPTASNSSNSQSEK
EDGTVSTANQNGVSSNGPGEILNKEEVKVEGLHINGPTGGNKKPLHADMDTNGYETDN
LTTDPKLAHMTARNENDFDEKSERPAKRRRVNSNGKESPGSSEFFQEAVSHGKFEELE
NTDD"
misc_feature 687..866
/note="Region: ELM2 domain"
misc_feature 1011..1142
/note="Region: SANT domain"
regulatory 4794..4799
/regulatory_class="polyA_signal_sequence"
BASE COUNT 1537 a 751 c 896 g 1632 t
ORIGIN
1 gcggctcctg cgcgttcccg ccgaggcagt ggcggcggga gcggcagaga cggcagcggc
61 cggagtcccg ttgctgagtc tcacatccgg gttctggccg tgacccagct gcggccgccg
121 cggagatgtg acccggcagt acggcaaata tggcggagcc atctgttgaa tcttcaagtc
181 caggaggttc agcaacatca gatgaccatg aatttgatcc atcagctgac atgctggttc
241 atgattttga tgatgaacga acattagaag aggaagaaat gatggaagga gaaacaaact
301 tcagctctga aatagaagat cttgcaaggg aaggcgacat gccaattcat gaacttctca
361 gcctttatgg ttatggtagt actgttcgac tacctgaaga agatgaggaa gaggaagaag
421 aggaagaaga aggtgaagat gatgaagatg ctgataatga tgacaacagt ggctgtagtg
481 gggaaaataa agaggagaat ataaaggatt catcaggtca ggaggatgaa actcagtctt
541 ccaatgatga tccatcacaa tctgttgctt ctcaagatgc ccaggaaata atccgcccac
601 gtcgatgtaa atattttgat acaaatagtg aagtagaaga agaatctgaa gaagatgaag
661 attatattcc atcagaagac tggaaaaagg agattatggt gggctccatg tttcaagcag
721 aaattccagt tggcatttgt agatacaaag aaaatgaaaa agtatatgaa aatgatgatc
781 agctcctgtg ggaccctgag tacttaccag aagataaagt gattatattt cttaaagatg
841 catctagaag aacaggtgat gagaagggtg tagaagcaat tcctgaagga tctcacataa
901 aagacaatga acaggcttta tatgaattgg ttaaatgcaa ttttgataca gaagaagcat
961 tgagaagatt aagatttaat gtaaaagcag ctagagagga attatctgtt tggacagagg
1021 aagagtgtag aaattttgaa caagggctga aggcctatgg aaaggatttt catttgattc
1081 aggctaataa agtccgaaca aggtcagttg gtgaatgtgt agcattctat tacatgtgga
1141 aaaaatctga acgttatgat ttctttgctc agcaaacacg atttggaaag aagaaatata
1201 atcttcatcc tggtgtaacg gattacatgg atcgtcttct agacgaaagt gaaagtgctg
1261 catctagtcg agcaccatcc cctcccccaa ctgcatcaaa cagtagtaac agccagtctg
1321 agaaagaaga tggcactgta agcactgcta atcaaaatgg agtgtcatct aatggaccag
1381 gtgaaatatt aaacaaagag gaagtaaaag ttgaagggtt acacattaat ggaccaacag
1441 gtggaaataa gaaaccactt catgcagata tggatactaa tggttatgaa acagataacc
1501 ttaccactga cccaaaactt gcccatatga ctgcaagaaa tgaaaatgat tttgatgaaa
1561 aaagtgagag acctgccaaa aggcgaaggg taaacagcaa tggaaaagaa agtccaggtt
1621 cttctgaatt tttccaagaa gcagtctcac atgggaaatt tgaagaactt gaaaacacag
1681 atgactaaat tttagaccta ttttactttc tttggagtaa attctggtgt gactaaaatt
1741 ttcagggttg atgggttacc ttaaaaagtt gatttccttg aagcagtttg aaaatttgaa
1801 ttgagtctta actttaggaa atgaggtttc ataattctgc cttttgcaga ttttttttac
1861 tttaaagctg tcagactctt ttaagggtat tttaaaaatt agtaaatttg aatgaactaa
1921 agatatatct ctaccttctc atttgaatat ctttagttca ttcagattta ctaattttgg
1981 taaatctgaa tgaactaaag atgtatctgt accttctcat ttgatgtatt aatcataaaa
2041 tttcactaca aggtaatttt tgcttagttt gatggatgaa tgggaaactc aagtccaaat
2101 ttctgcttaa taccaatttc tctgagtttc ttgaaatgtc tttaaaacag acatttttct
2161 caccaaacag tttgagtatc tttattaagg aaacccttac gaatcctgaa aattatgcta
2221 gcatgatttt tttatatata gaagtttaaa aataaaccag gtcaggtttg tatatgtaaa
2281 attgttgaca tcaatgatgt ctttccatat tcttatctgg gcttaagaaa tacattctgt
2341 atttttccag attctttgta gcctttgaaa gatttttaca gtacatatgt cttgactgag
2401 ctgtcctttc ttaatacaaa agcgtgtata attttcttaa cttgtacagt tggtaaactt
2461 ttatgagagg aattgttatt ctgagtctgt cagctttcat tttattttgc taaggttttt
2521 ctaatgaatt tttaagtgtt tgtgtagtaa ttaagtcata tttcttatcc aggtggttaa
2581 agcattcata aaggattata aaattttttt tttttttttt ttaaatttct acttaagggc
2641 aagtaatttg agaattctga aattaagcat gatgcttaga ttgcagtttg ttttgcattt
2701 gctctaattt tcaaaattat ttttgaagca agacaaaagt ttaatgtcag cttaagtgct
2761 taaatatatc atgctgacca gaatcctgtt atttttatat gcatcataaa atttcccatt
2821 tctgcattaa ataaacagag gaggggggtc aagtgatact tagatattgg cacacacaag
2881 gaacaactgt tggcaggcag tatcgatttt atgaagagaa agtgaagttt gaaaactttt
2941 caaacttttc tagttacaat ccaatttttc agatttgata atgcttttcc aaagtgaaaa
3001 taagatacac aataatcatt gctttttgtg attacagata ggattatcca tctgcatagc
3061 cttgtaaaag tgccatttta tttttagtgc taaattcttg ttaaataatg tagttttata
3121 tagctgatag accaacctat atccaaactt ttataaaata ttaattattc ttgtttttct
3181 cacacaggca tactccaaat gcttcttcca gttcattttt cagccatcag ttcaagagcc
3241 aatgcctttt taaaataaag cttctgtggt cttgttttta atggctcaac tgtctgatgt
3301 aattgagtga aggtttgcac tgagaaatta gcattcaggc cttaccccca tgaagtatta
3361 ctgttaacat atgttcggac tgcttccctt caccaatgtg aacaactttt tttcccaaac
3421 agtattaaaa gccactttgc aacacttgac ttcatcttaa tgtacattca ctgttgttac
3481 atacatatct aagtaaatca aagttttggg tggaagtgtt gagaagtatg agttttttgt
3541 tgtttttgtt ttacttaaaa cttttaattt atccagaatg gcagtagctt tagcaagcag
3601 atggtcacaa tctgttttct aaatcatttt ttattaaatg aatccaaagt atcctagctc
3661 tttgtcaaag atggtctgta gaaatgtttt taaagattag ggatgctgta ctttttgaat
3721 tgttgcagtg ttggagatgc cattttcacc tttttaaaaa gatgcatttt atttgcaggt
3781 ttgtgaagtt cttgcaaact cttactacag aaatgtttta aatacattct caggcatgtt
3841 tgcaaaaata tggcacatgt atacatttta ggaaatgtta cttttgttaa tctttaaaaa
3901 atacacctaa tgaaagacat tccactatta tgcgtaatgc tcagcttttt gtaaagaaat
3961 atttaattgt attttgtgtt tatacaggta tttcacacaa taatttgttc ttaatgcagc
4021 cactataact tgataagtca ttgcactatt taaaaagttt tagtaatatc atgaatttaa
4081 tttgcttaag atttagtaca tttcagaact tttgaacttt tgacaaattg cattgggaaa
4141 agaagtctgt taatagtgat ttagtctccc cgcctcattc ccacccccaa caaagcacta
4201 tcattttcat ttggaatggg tatttttctg tttcatgatg tattttcaaa tagagttcag
4261 gatctgcaat tcagttcaac acaagtttgt tgagctttaa aatgtatttg aagtaatatt
4321 taaataggca tttaaaattt caaattagat gttaaattta tgcatagtaa ttttgcactg
4381 taaaataatt cccttctccc attccttgtc tgccattctg aatatgctta ttaaaatatt
4441 tttttaaaca tatttgccta cataatactg tgtgaatatt ttcattagat taattcacta
4501 agattttatt agagattgtt tgaatgatgc atgttattga caaggcaaat atatatatat
4561 acacagtctg tttcttctat tcctagacat attgcactac tttttcagtg gttcttggtc
4621 ccctttacca catcttgggt gatgtatttt tgtcttcttc ccctttgcca caagagatcc
4681 tttcagtccc tagacctcca ttcactctgt ttctcttctg ctggattata taatttaaaa
4741 ataatgtgtt cccgtatttt gtagtggagt tcatatcaca ttatgttttg caaaataaaa
4801 cttgttttgt cacaat
//