LOCUS AF510503 5146 bp mRNA linear HUM 30-OCT-2002
DEFINITION Homo sapiens Na+/Ca2+ exchanger isoform 3 splice variant 4 (SLC8A3)
mRNA, complete cds; alternatively spliced.
ACCESSION AF510503
VERSION AF510503.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5146)
AUTHORS Gabellini,N., Bortoluzzi,S., Danieli,G.A. and Carafoli,E.
TITLE The human SLC8A3 gene and the tissue-specific Na(+)/Ca(2+)
exchanger 3 isoforms
JOURNAL Gene 298 (1), 1-7 (2002)
PUBMED 12406570
REFERENCE 2 (bases 1 to 5146)
AUTHORS Gabellini,N., Bortoluzzi,S., Danieli,G.A. and Carafoli,E.
TITLE Direct Submission
JOURNAL Submitted (09-MAY-2002) Department of Biology, Unv. of Padova, via
G. Colombo, Padova, PD 35131, Italy
FEATURES Location/Qualifiers
source 1..5146
/db_xref="H-InvDB:HIT000081048"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="14"
/map="14q24.2"
gene 1..5146
/gene="SLC8A3"
5'UTR 1..754
/gene="SLC8A3"
CDS 755..2617
/gene="SLC8A3"
/note="NCX3.4; expressed in skeletal muscle; alternatively
spliced"
/codon_start=1
/product="Na+/Ca2+ exchanger isoform 3 splice variant 4"
/protein_id="AAN60792.1"
/translation="MAWLRLQPLTSAFLHFGLVTFVLFLNGLRAEAGGSGDVPSTGQN
NESCSGSSDCKEGVILPIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASI
EVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGF
IAGDLGPSTIVGSAAFNMFIIIGICVYVIPDGETRKIKHLRVFFITAAWSIFAYIWLY
MILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIE
TEGDHPKGIEMDGKMMNSHFLDGNLVPLEGKEVDESRREMIRILKDLKQKHPEKDLDQ
LVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKASSMSEVHTDEPE
DFISKVFFDPCSYQCLENCGAVLLTVVRKGGDMSKTMYVDYKTEDGSANAGADYEFTE
GTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRIEEEQPEEGMPPAIFNSLPL
PRAVLASPCVATVTILDDDHAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPF
RTVEGTAKGGGEDFEDTYGELEFKNDETVCDRQEADYGRRGGQEDSRDGKASIG"
3'UTR 2618..5146
/gene="SLC8A3"
regulatory 5117..5122
/regulatory_class="polyA_signal_sequence"
/gene="SLC8A3"
BASE COUNT 1216 a 1338 c 1330 g 1262 t
ORIGIN
1 cggcgctgtc tcccagctga tagggtgacg ttccgtttgg aggcttggag attggctttt
61 tgatttggct tcttccggca gcttaatggg caaagctctc cgctcgccca gaaaccagcc
121 tctccgcgcg tcccctctgc gcgcggcgag gccgagacgt ctcccgcggt gacagcgtgc
181 aaggcggaga cccggcgcgc tcccagccca gggaaagccc aggcgacgcg accgcaagcc
241 cgagcccagg tccctcggag ccgccagggc gcgccgggct gcttgccttc ctgccccttc
301 ctgcaggaat cccccgccgc ccgcggccgg gactccgggc ctctcccggg cgtagattcc
361 agtcaccgct ctgggtcggg gtttccctct ttctgaaatc cgtgcggaag gacccctccc
421 ggggcccctc gccctggccc cagacaccct ccctcccaga ccccgcgctc cagatgcgct
481 gccccgcagc tccctgacag ctgcgagccc acgaaccccg gcgggagggc ggcggcggcg
541 gactgacatg ccccggacgc ggctgcggcc ggcgggcagc ccgcgggggc gatgagccgc
601 tgcgaccggt gaggcgccgg gcggcggggg catcgcgtac cttcctcacc cccctccctt
661 gcccactccg ctcgggaggc cgagaggaaa cggtctctgg cctatcagga ggacaactgg
721 tgctgcaata gaagccagtg gctaagtctc gtgtatggcg tggttaaggt tgcagcctct
781 cacctctgcc ttcctccatt ttgggctggt tacctttgtg ctcttcctga atggtcttcg
841 agcagaggct ggtggctcag gggacgtgcc aagcacaggg cagaacaatg agtcctgttc
901 agggtcatcg gactgcaagg agggtgtcat cctgccaatc tggtacccgg agaacccttc
961 ccttggggac aagattgcca gggtcattgt ctattttgtg gccctgatat acatgttcct
1021 tggggtgtcc atcattgctg accgcttcat ggcatctatt gaagtcatca cctctcaaga
1081 gagggaggtg acaattaaga aacccaatgg agaaaccagc acaaccacta ttcgggtctg
1141 gaatgaaact gtctccaacc tgacccttat ggccctgggt tcctctgctc ctgagatact
1201 cctctcttta attgaggtgt gtggtcatgg gttcattgct ggtgatctgg gaccttctac
1261 cattgtaggg agtgcagcct tcaacatgtt catcatcatt ggcatctgtg tctacgtgat
1321 cccagacgga gagactcgca agatcaagca tctacgagtc ttcttcatca ccgctgcttg
1381 gagtatcttt gcctacatct ggctctatat gattctggca gtcttctccc ctggtgtggt
1441 ccaggtttgg gaaggcctcc tcactctctt cttctttcca gtgtgtgtcc ttctggcctg
1501 ggtggcagat aaacgactgc tcttctacaa atacatgcac aaaaagtacc gcacagacaa
1561 acaccgagga attatcatag agacagaggg tgaccaccct aagggcattg agatggatgg
1621 gaaaatgatg aattcccatt ttctagatgg gaacctggtg cccctggaag ggaaggaagt
1681 ggatgagtcc cgcagagaga tgatccggat tctcaaggat ctgaagcaaa aacacccaga
1741 gaaggactta gatcagctgg tggagatggc caattactat gctctttccc accaacagaa
1801 gagccgtgcc ttctaccgta tccaagccac tcgtatgatg actggtgcag gcaatatcct
1861 gaagaaacat gcagcagaac aagccaagaa ggcctccagc atgagcgagg tgcacaccga
1921 tgagcctgag gactttattt ccaaggtctt ctttgaccca tgttcttacc agtgcctgga
1981 gaactgtggg gctgtactcc tgacagtggt gaggaaaggg ggagacatgt caaagaccat
2041 gtatgtggac tacaaaacag aggatggttc tgccaatgca ggggctgact atgagttcac
2101 agagggcacg gtggttctga agccaggaga gacccagaag gagttctccg tgggcataat
2161 tgatgacgac atttttgagg aggatgaaca cttctttgta aggttgagca atgtccgcat
2221 agaggaggag cagccagagg aggggatgcc tccagcaata ttcaacagtc ttcccttgcc
2281 tcgggctgtc ctagcctccc cttgtgtggc cacagttacc atcttggatg atgaccatgc
2341 aggcatcttc acttttgaat gtgatactat tcatgtcagt gagagtattg gtgttatgga
2401 ggtcaaggtt ctgcggacat caggtgcccg gggtacagtc atcgtcccct ttaggacagt
2461 agaagggaca gccaagggtg gcggtgagga ctttgaagac acatatgggg agttggaatt
2521 caagaatgat gaaactgtat gtgacagaca ggaagctgac tatggaagaa gaggaggcca
2581 agaggatagc agagatggga aagccagtat tgggtgaaca ccccaaacta gaagtcatca
2641 ttgaagagtc ctatgagttc aagactacgg tggacaaact gatcaagaag acaaacctgg
2701 ccttggttgt ggggacccat tcctggaggg accagttcat ggaggccatc accgtcagtg
2761 cagcagggga tgaggatgag gatgaatccg gggaggagag gctgccctcc tgctttgact
2821 acgtcatgca cttcctgact gtcttctgga aggtgctgtt tgcctgtgtg ccccccacag
2881 agtactgcca cggctgggcc tgcttcgccg tctccatcct catcattggc atgctcaccg
2941 ccatcattgg ggacctggcc tcgcacttcg gctgcaccat tggtctcaaa gattcagtca
3001 cagctgttgt tttcgtggca tttggcacct ctgtcccaga tacgtttgcc agcaaagctg
3061 ctgccctcca ggatgtatat gcagacgcct ccattggcaa cgtgacgggc agcaacgccg
3121 tcaatgtctt cctgggcatc ggcctggcct ggtccgtggc cgccatctac tgggctctgc
3181 agggacagga gttccacgtg tcggccggca cactggcctt ctccgtcacc ctcttcacca
3241 tctttgcatt tgtctgcatc agcgtgctct tgtaccgaag gcggccgcac ctgggagggg
3301 agcttggtgg cccccgtggc tgcaagctcg ccacaacatg gctctttgtg agcctgtggc
3361 tcctctacat actctttgcc acactagagg cctattgcta catcaagggg ttctaagcca
3421 cacaacagag cctccagcag ggcaggccta ggacttctcc taagagaagg gcacttcccc
3481 accagtgatc tctcccgact gcactgccct ggagaggcag catcaggacc taagccccag
3541 gaacttcacc caacttaggc cctggcaatt aactgaaagg gcaaagtctt aatcaatcaa
3601 acaatggagg aatcaccgac tttacacagt atttaattga atacaaacaa gcaacagcaa
3661 caaatccacc tccaccccat ctccccctca tatccctgac ccaaagcaaa ggtcagagcc
3721 tttcgcctcc ttctattcca tcttttgatt attcctttgc ctctcatttc tttggaagca
3781 gggtttctcc tctctgccca attccatatg tccctattat ctcactcagc tgacaagacg
3841 tgaaaatgag tcacattcat gtggctgggg tggggttctt ttttcattgt aatcattatt
3901 gtggttgctt tcgttttgcc attaggtttt gcttattatt ttgttttgtc ttttttttct
3961 gaagtgagtg aaaaaggtgc cacaaaggaa ttccaggtcc gagccaacag agagaaacat
4021 gaatttttag acacatgctc tcctgccacc tcttggctcc atcaagatcc agttccccat
4081 ctcactgttt tctctgagtt cttgggagga gtgatggtgt tggggtagaa ataagctcac
4141 tcacccacgc agggtactaa agatcttaca ggagcttcaa ctggagcagg aggagctttt
4201 tatgcttatg ttgaatcaag tcagatacaa aaagcaattg tccctctttg cccaagcctt
4261 tccaattctg tgtgtcttgt tgtgtcagtg tccacttgtg tatccttctg caggaagacc
4321 cgccaaatag aagagatggg acaaaaatag gaatggtgtg tgacgacaaa gggctactgg
4381 aagaacaaaa gggatacagg ccttcttgat tatctttggc tttgtacctg aggcaggaga
4441 gaagagatgt ccaaccagtg agatctttaa gagaaaagtt tgtattttaa atgtcaatgt
4501 gcctgagaaa tgtcagcttc accacgctct tgcttcctaa tgctctatac aaagagggct
4561 gactatattt cttgaagtgg tgtaaaaact tagagatttt ataagagaac caggggctcc
4621 cttcacctct cctggtccct caggtcacat atgaaagcat ttttacaaga taggaactgg
4681 aattcctcat ttctcccatg ttcctgcttg ttcttaaact tcatgaagct atttttccag
4741 cctatggggt agttcttgct ccagtaagag gaatcttagt tgtcataatc ccttggagcc
4801 tgggtttttg gagaaagaga tctccgtgcc ctacagacct tttctcaacg aatgtgggaa
4861 ggacctggct ttaaaacacg cacacaaaca cacaaataaa cagacataag atgtcatcac
4921 gaaactgccc acggatcttt aggctttctg cattgacata aatacatttt ctaagggggg
4981 gggggaagaa attaaaaaac acctgttaat tttaaacaca ttttttaaga aaaaaataat
5041 taaaaaagaa acagtgctca tgtcataagc tatgttgaca gttgccagtg gaaatgttgg
5101 gttggttcaa aaaaaaaata aaagctatac tatatctctc tacata
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