LOCUS AF510502 5268 bp mRNA linear HUM 30-OCT-2002
DEFINITION Homo sapiens Na+/Ca2+ exchanger isoform 3 splice variant 3 (SLC8A3)
mRNA, complete cds; alternatively spliced.
ACCESSION AF510502
VERSION AF510502.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5268)
AUTHORS Gabellini,N., Bortoluzzi,S., Danieli,G.A. and Carafoli,E.
TITLE The human SLC8A3 gene and the tissue-specific Na(+)/Ca(2+)
exchanger 3 isoforms
JOURNAL Gene 298 (1), 1-7 (2002)
PUBMED 12406570
REFERENCE 2 (bases 1 to 5268)
AUTHORS Gabellini,N., Bortoluzzi,S., Danieli,G.A. and Carafoli,E.
TITLE Direct Submission
JOURNAL Submitted (09-MAY-2002) Department of Biology, Unv. of Padova, via
G. Colombo, Padova, PD 35131, Italy
FEATURES Location/Qualifiers
source 1..5268
/db_xref="H-InvDB:HIT000081047"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="14"
/map="14q24.2"
gene 1..5268
/gene="SLC8A3"
5'UTR 1..754
/gene="SLC8A3"
CDS 755..3538
/gene="SLC8A3"
/note="NCX3.3; expressed in skeletal muscle; alternatively
spliced"
/codon_start=1
/product="Na+/Ca2+ exchanger isoform 3 splice variant 3"
/protein_id="AAN60791.1"
/translation="MAWLRLQPLTSAFLHFGLVTFVLFLNGLRAEAGGSGDVPSTGQN
NESCSGSSDCKEGVILPIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASI
EVITSQEREVTIKKPNGETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGF
IAGDLGPSTIVGSAAFNMFIIIGICVYVIPDGETRKIKHLRVFFITAAWSIFAYIWLY
MILAVFSPGVVQVWEGLLTLFFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIE
TEGDHPKGIEMDGKMMNSHFLDGNLVPLEGKEVDESRREMIRILKDLKQKHPEKDLDQ
LVEMANYYALSHQQKSRAFYRIQATRMMTGAGNILKKHAAEQAKKASSMSEVHTDEPE
DFISKVFFDPCSYQCLENCGAVLLTVVRKGGDMSKTMYVDYKTEDGSANAGADYEFTE
GTVVLKPGETQKEFSVGIIDDDIFEEDEHFFVRLSNVRIEEEQPEEGMPPAIFNSLPL
PRAVLASPCVATVTILDDDHAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPF
RTVEGTAKGGGEDFEDTYGELEFKNDETVKTIRVKIVDEEEYERQENFFIALGEPKWM
ERGISALLLSPDVTDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDK
LIKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWK
VLFACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFG
TSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHV
SAGTLAFSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYIL
FATLEAYCYIKGF"
3'UTR 3539..5268
/gene="SLC8A3"
regulatory 5239..5244
/regulatory_class="polyA_signal_sequence"
/gene="SLC8A3"
BASE COUNT 1258 a 1358 c 1362 g 1290 t
ORIGIN
1 cggcgctgtc tcccagctga tagggtgacg ttccgtttgg aggcttggag attggctttt
61 tgatttggct tcttccggca gcttaatggg caaagctctc cgctcgccca gaaaccagcc
121 tctccgcgcg tcccctctgc gcgcggcgag gccgagacgt ctcccgcggt gacagcgtgc
181 aaggcggaga cccggcgcgc tcccagccca gggaaagccc aggcgacgcg accgcaagcc
241 cgagcccagg tccctcggag ccgccagggc gcgccgggct gcttgccttc ctgccccttc
301 ctgcaggaat cccccgccgc ccgcggccgg gactccgggc ctctcccggg cgtagattcc
361 agtcaccgct ctgggtcggg gtttccctct ttctgaaatc cgtgcggaag gacccctccc
421 ggggcccctc gccctggccc cagacaccct ccctcccaga ccccgcgctc cagatgcgct
481 gccccgcagc tccctgacag ctgcgagccc acgaaccccg gcgggagggc ggcggcggcg
541 gactgacatg ccccggacgc ggctgcggcc ggcgggcagc ccgcgggggc gatgagccgc
601 tgcgaccggt gaggcgccgg gcggcggggg catcgcgtac cttcctcacc cccctccctt
661 gcccactccg ctcgggaggc cgagaggaaa cggtctctgg cctatcagga ggacaactgg
721 tgctgcaata gaagccagtg gctaagtctc gtgtatggcg tggttaaggt tgcagcctct
781 cacctctgcc ttcctccatt ttgggctggt tacctttgtg ctcttcctga atggtcttcg
841 agcagaggct ggtggctcag gggacgtgcc aagcacaggg cagaacaatg agtcctgttc
901 agggtcatcg gactgcaagg agggtgtcat cctgccaatc tggtacccgg agaacccttc
961 ccttggggac aagattgcca gggtcattgt ctattttgtg gccctgatat acatgttcct
1021 tggggtgtcc atcattgctg accgcttcat ggcatctatt gaagtcatca cctctcaaga
1081 gagggaggtg acaattaaga aacccaatgg agaaaccagc acaaccacta ttcgggtctg
1141 gaatgaaact gtctccaacc tgacccttat ggccctgggt tcctctgctc ctgagatact
1201 cctctcttta attgaggtgt gtggtcatgg gttcattgct ggtgatctgg gaccttctac
1261 cattgtaggg agtgcagcct tcaacatgtt catcatcatt ggcatctgtg tctacgtgat
1321 cccagacgga gagactcgca agatcaagca tctacgagtc ttcttcatca ccgctgcttg
1381 gagtatcttt gcctacatct ggctctatat gattctggca gtcttctccc ctggtgtggt
1441 ccaggtttgg gaaggcctcc tcactctctt cttctttcca gtgtgtgtcc ttctggcctg
1501 ggtggcagat aaacgactgc tcttctacaa atacatgcac aaaaagtacc gcacagacaa
1561 acaccgagga attatcatag agacagaggg tgaccaccct aagggcattg agatggatgg
1621 gaaaatgatg aattcccatt ttctagatgg gaacctggtg cccctggaag ggaaggaagt
1681 ggatgagtcc cgcagagaga tgatccggat tctcaaggat ctgaagcaaa aacacccaga
1741 gaaggactta gatcagctgg tggagatggc caattactat gctctttccc accaacagaa
1801 gagccgtgcc ttctaccgta tccaagccac tcgtatgatg actggtgcag gcaatatcct
1861 gaagaaacat gcagcagaac aagccaagaa ggcctccagc atgagcgagg tgcacaccga
1921 tgagcctgag gactttattt ccaaggtctt ctttgaccca tgttcttacc agtgcctgga
1981 gaactgtggg gctgtactcc tgacagtggt gaggaaaggg ggagacatgt caaagaccat
2041 gtatgtggac tacaaaacag aggatggttc tgccaatgca ggggctgact atgagttcac
2101 agagggcacg gtggttctga agccaggaga gacccagaag gagttctccg tgggcataat
2161 tgatgacgac atttttgagg aggatgaaca cttctttgta aggttgagca atgtccgcat
2221 agaggaggag cagccagagg aggggatgcc tccagcaata ttcaacagtc ttcccttgcc
2281 tcgggctgtc ctagcctccc cttgtgtggc cacagttacc atcttggatg atgaccatgc
2341 aggcatcttc acttttgaat gtgatactat tcatgtcagt gagagtattg gtgttatgga
2401 ggtcaaggtt ctgcggacat caggtgcccg gggtacagtc atcgtcccct ttaggacagt
2461 agaagggaca gccaagggtg gcggtgagga ctttgaagac acatatgggg agttggaatt
2521 caagaatgat gaaactgtga aaaccataag ggttaaaata gtagatgagg aggaatacga
2581 aaggcaagag aatttcttca ttgcccttgg tgaaccgaaa tggatggaac gtggaatatc
2641 agcgctcctg ttatctccag atgtgacaga caggaagctg actatggaag aagaggaggc
2701 caagaggata gcagagatgg gaaagccagt attgggtgaa caccccaaac tagaagtcat
2761 cattgaagag tcctatgagt tcaagactac ggtggacaaa ctgatcaaga agacaaacct
2821 ggccttggtt gtggggaccc attcctggag ggaccagttc atggaggcca tcaccgtcag
2881 tgcagcaggg gatgaggatg aggatgaatc cggggaggag aggctgccct cctgctttga
2941 ctacgtcatg cacttcctga ctgtcttctg gaaggtgctg tttgcctgtg tgccccccac
3001 agagtactgc cacggctggg cctgcttcgc cgtctccatc ctcatcattg gcatgctcac
3061 cgccatcatt ggggacctgg cctcgcactt cggctgcacc attggtctca aagattcagt
3121 cacagctgtt gttttcgtgg catttggcac ctctgtccca gatacgtttg ccagcaaagc
3181 tgctgccctc caggatgtat atgcagacgc ctccattggc aacgtgacgg gcagcaacgc
3241 cgtcaatgtc ttcctgggca tcggcctggc ctggtccgtg gccgccatct actgggctct
3301 gcagggacag gagttccacg tgtcggccgg cacactggcc ttctccgtca ccctcttcac
3361 catctttgca tttgtctgca tcagcgtgct cttgtaccga aggcggccgc acctgggagg
3421 ggagcttggt ggcccccgtg gctgcaagct cgccacaaca tggctctttg tgagcctgtg
3481 gctcctctac atactctttg ccacactaga ggcctattgc tacatcaagg ggttctaagc
3541 cacacaacag agcctccagc agggcaggcc taggacttct cctaagagaa gggcacttcc
3601 ccaccagtga tctctcccga ctgcactgcc ctggagaggc agcatcagga cctaagcccc
3661 aggaacttca cccaacttag gccctggcaa ttaactgaaa gggcaaagtc ttaatcaatc
3721 aaacaatgga ggaatcaccg actttacaca gtatttaatt gaatacaaac aagcaacagc
3781 aacaaatcca cctccacccc atctccccct catatccctg acccaaagca aaggtcagag
3841 cctttcgcct ccttctattc catcttttga ttattccttt gcctctcatt tctttggaag
3901 cagggtttct cctctctgcc caattccata tgtccctatt atctcactca gctgacaaga
3961 cgtgaaaatg agtcacattc atgtggctgg ggtggggttc ttttttcatt gtaatcatta
4021 ttgtggttgc tttcgttttg ccattaggtt ttgcttatta ttttgttttg tctttttttt
4081 ctgaagtgag tgaaaaaggt gccacaaagg aattccaggt ccgagccaac agagagaaac
4141 atgaattttt agacacatgc tctcctgcca cctcttggct ccatcaagat ccagttcccc
4201 atctcactgt tttctctgag ttcttgggag gagtgatggt gttggggtag aaataagctc
4261 actcacccac gcagggtact aaagatctta caggagcttc aactggagca ggaggagctt
4321 tttatgctta tgttgaatca agtcagatac aaaaagcaat tgtccctctt tgcccaagcc
4381 tttccaattc tgtgtgtctt gttgtgtcag tgtccacttg tgtatccttc tgcaggaaga
4441 cccgccaaat agaagagatg ggacaaaaat aggaatggtg tgtgacgaca aagggctact
4501 ggaagaacaa aagggataca ggccttcttg attatctttg gctttgtacc tgaggcagga
4561 gagaagagat gtccaaccag tgagatcttt aagagaaaag tttgtatttt aaatgtcaat
4621 gtgcctgaga aatgtcagct tcaccacgct cttgcttcct aatgctctat acaaagaggg
4681 ctgactatat ttcttgaagt ggtgtaaaaa cttagagatt ttataagaga accaggggct
4741 cccttcacct ctcctggtcc ctcaggtcac atatgaaagc atttttacaa gataggaact
4801 ggaattcctc atttctccca tgttcctgct tgttcttaaa cttcatgaag ctatttttcc
4861 agcctatggg gtagttcttg ctccagtaag aggaatctta gttgtcataa tcccttggag
4921 cctgggtttt tggagaaaga gatctccgtg ccctacagac cttttctcaa cgaatgtggg
4981 aaggacctgg ctttaaaaca cgcacacaaa cacacaaata aacagacata agatgtcatc
5041 acgaaactgc ccacggatct ttaggctttc tgcattgaca taaatacatt ttctaagggg
5101 gggggggaag aaattaaaaa acacctgtta attttaaaca cattttttaa gaaaaaaata
5161 attaaaaaag aaacagtgct catgtcataa gctatgttga cagttgccag tggaaatgtt
5221 gggttggttc aaaaaaaaaa taaaagctat actatatctc tctacata
//