LOCUS AF509887 1466 bp mRNA linear HUM 07-NOV-2002
DEFINITION Homo sapiens keratin 7 (KRT7) mRNA, complete cds.
ACCESSION AF509887
VERSION AF509887.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1466)
AUTHORS Smith,F.J., Porter,R.M., Corden,L.D., Lunny,D.P., Lane,E.B. and
McLean,W.H.
TITLE Cloning of human, murine, and marsupial keratin 7 and a survey of
K7 expression in the mouse
JOURNAL Biochem. Biophys. Res. Commun. 297 (4), 818-827 (2002)
PUBMED 12359226
REFERENCE 2 (bases 1 to 1466)
AUTHORS Smith,F.J.D. and McLean,W.H.I.
TITLE Direct Submission
JOURNAL Submitted (06-MAY-2002) Human Genetics Unit, University of Dundee,
Ninewells Medical School, Dundee DD1 9SY, UK
FEATURES Location/Qualifiers
source 1..1466
/db_xref="H-InvDB:HIT000081036"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..1466
/gene="KRT7"
5'UTR 1..56
/gene="KRT7"
CDS 57..1466
/gene="KRT7"
/note="intermediate filament protein; K7"
/codon_start=1
/product="keratin 7"
/protein_id="AAN64031.1"
/translation="MSIHFSSPVFTSRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGA
SRPRVAVRSAYGGPVGAGIREVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKF
ASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRLPDIFEAQIAGLRGQLEALQVDGG
RLEAELRSMQDVVEDFKNKYEDEINRRTAAENEFVVLKKDVDAAYMSKVELEAKVDAL
NDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSR
AEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEA
AIAEAEERGELALKDARAKQEELEAALQRAKQDMARQLREYQELMSVKLALDIEIATY
RKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGIGLTLGGTMGSNALSFSSSAGPG
LLKAYSIRTASASRRSARD"
variation 1147
/gene="KRT7"
/note="converts alanine to glycine"
/replace="g"
BASE COUNT 300 a 431 c 490 g 245 t
ORIGIN
1 acggcgagtg cgcgctcctc ctcgcccgcc gctaggtcca tcccggccca gccaccatgt
61 ccatccactt cagctccccg gtattcacct cgcgctcagc cgccttctcg ggccgcggcg
121 cccaggtgcg cctgagctcc gctcgccccg gcggccttgg cagcagcagc ctctacggcc
181 tcggcgcctc gcggccgcgc gtggccgtgc gctctgccta tgggggcccg gtgggcgccg
241 gcatccgcga ggtcaccatt aaccagagcc tgctggcccc gctgcggctg gacgccgacc
301 cctccctcca gcgggtgcgc caggaggaga gcgagcagat caagaccctc aacaacaagt
361 ttgcctcctt catcgacaag gtgcggtttc tggagcagca gaacaagctg ctggagacca
421 agtggacgct gctgcaggag cagaagtcgg ccaagagcag ccgcctccca gacatctttg
481 aggcccagat tgctggcctt cggggtcagc ttgaggcact gcaggtggat gggggccgcc
541 tggaggcgga gctgcggagc atgcaggatg tggtggagga cttcaagaat aagtacgaag
601 atgaaattaa ccgccgcaca gctgctgaga atgagtttgt ggtgctgaag aaggatgtgg
661 atgctgccta catgagcaag gtggagctgg aggccaaggt ggatgccctg aatgatgaga
721 tcaacttcct caggaccctc aatgagacgg agttgacaga gctgcagtcc cagatctccg
781 acacatctgt ggtgctgtcc atggacaaca gtcgctccct ggacctggac ggcatcatcg
841 ctgaggtcaa ggcacagtat gaggagatgg ccaaatgcag ccgggctgag gctgaagcct
901 ggtaccagac caagtttgag accctccagg cccaggctgg gaagcatggg gacgacctcc
961 ggaatacccg gaatgagatt tcagagatga accgggccat ccagaggctg caggctgaga
1021 tcgacaacat caagaaccag cgtgccaagt tggaggccgc cattgccgag gctgaggagc
1081 gtggggagct ggcgctcaag gatgctcgtg ccaagcagga ggagctggaa gccgccctgc
1141 agcgggccaa gcaggatatg gcacggcagc tgcgtgagta ccaggaactc atgagcgtga
1201 agctggccct ggacatcgag atcgccacct accgcaagct gctggagggc gaggagagcc
1261 ggttggctgg agatggagtg ggagccgtga atatctctgt gatgaattcc actggtggca
1321 gtagcagtgg cggtggcatt gggctgaccc tcgggggaac catgggcagc aatgccctga
1381 gcttctccag cagtgcgggt cctgggctcc tgaaggctta ttccatccgg accgcatccg
1441 ccagtcgcag gagtgcccgc gactga
//