LOCUS AF497516 3266 bp mRNA linear HUM 13-AUG-2002
DEFINITION Homo sapiens adenylate cyclase type IV (ADCY4) mRNA, complete cds.
ACCESSION AF497516
VERSION AF497516.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3266)
AUTHORS Ludwig,M.G. and Seuwen,K.
TITLE Characterization of the human adenylyl cyclase gene family: cDNA,
gene structure, and tissue distribution of the nine isoforms
JOURNAL J. Recept. Signal Transduct. Res. 22 (1-4), 79-110 (2002)
PUBMED 12503609
REFERENCE 2 (bases 1 to 3266)
AUTHORS Ludwig,M.G. and Seuwen,K.
TITLE Direct Submission
JOURNAL Submitted (29-MAR-2002) Novartis Pharma AG, Klybeckstrasse, Basel
4002, Switzerland
FEATURES Location/Qualifiers
source 1..3266
/db_xref="H-InvDB:HIT000080824"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="14"
/map="14q11"
/tissue_type="spleen"
gene 1..3266
/gene="ADCY4"
CDS 7..3240
/gene="ADCY4"
/EC_number="4.6.1.1"
/codon_start=1
/product="adenylate cyclase type IV"
/protein_id="AAM94373.1"
/translation="MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLGIVLCALAAL
LAVAWASGRELTSDPSFLTTVLCALGGFSLLLGLASREQRLQRWTRPLSGLVWVALLA
LGHAFLFTGGVVSAWDQVSYFLFVIFTAYAMLPLGMRDAAVAGLASSLSHLLVLGLYL
GPQPDSRPALLPQLAANAVLFLCGNVAGVYHKALMERALRATFREALSSLHSRRRLDT
EKKHQEHLLLSILPAYLAREMKAEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLY
ADIVGFTRLASECSPKELVLMLNELFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSL
PDHAINCVRMGLDMCRAIRKLRAATGVDINMRVGVHSGSVLCGVIGLQKWQYDVWSHD
VTLANHMEAGGVPGRVHITGATLALLAGAYAVEDAGMEHRDPYLRELGEPTYLVIDPR
AEEEDEKGTAGGLLSSLEGLKMRPSLLMTRYLESWGAAKPFAHLSHGDSPVSTSTPLP
EKTLASFSTQWSLDRSRTPRGLDDELDTGDAKFFQVIEQLNSQKQWKQSKDFNPLTLY
FREKEMEKEYRLSAIPAFKYYEACTFLVFLSNFIIQMLVTNRPPALAITYSITFLLFL
LILFVCFSEDLMRCVLKGPKMLHWLPALSGLVATRPGLRIALGTATILLVFAMAITSL
FFFPTSSDCPFQAPNVSSMISNLSWELPGSLPLISVPYSMHCCTLGFLSCSLFLHMSF
ELKLLLLLLWLAASCSLFLHSHAWLSECLIVRLYLGPLDSRPGVLKEPKLMGAISFFI
FFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRLLLENVLPAHVAPQFIG
QNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLRLLNEIIADFDELLS
KPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQDAERSCSHLGTMVEFAVALGSKLDV
INKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTE
ETAWALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRTGPPSATLG"
BASE COUNT 639 a 1015 c 914 g 698 t
ORIGIN
1 gagatcatgg cccgcctctt cagcccccgg ccgcccccca gcgaagacct cttctacgag
61 acctactaca gcctgagcca gcagtacccg ctgctgctgc tgctgctggg gatcgtgctc
121 tgtgcgctcg cggcgctgct cgcagtggcc tgggccagcg gcagggagct gacctcagac
181 ccgagcttcc tgaccactgt gctgtgcgcg ctgggcggct tctcgctgct gctgggcctc
241 gcttcccggg agcagcgact gcagcgctgg acgcgtcccc tgtccggctt ggtatgggtc
301 gcgctgctag cgctaggcca cgccttcctg ttcaccgggg gcgtggtgag cgcctgggac
361 caggtgtcct attttctctt cgtcatcttc acggcgtatg ccatgctgcc cttgggcatg
421 cgggacgccg ccgtcgcggg cctcgcctcc tcactctcgc atctgctggt cctcgggctg
481 tatcttgggc cacagccgga ctcacggcct gcactgctgc cgcagttggc agcaaacgca
541 gtgctgttcc tgtgcgggaa cgtggcagga gtgtaccaca aggcgctgat ggagcgcgcc
601 ctgcgggcca cgttccggga ggcactcagc tccctgcact cacgccggcg gctggacacc
661 gagaagaagc accaggaaca ccttctcttg tccatccttc ctgcctacct ggcccgagag
721 atgaaggcag agatcatggc acggctgcag gcaggacagg ggtcacggcc agagagcact
781 aacaatttcc acagcctcta tgtcaagagg caccagggag tcagcgtgct gtatgctgac
841 atcgtgggct tcacgcggct ggccagcgag tgttccccta aggagctggt gctcatgctc
901 aatgagctct ttggcaagtt cgaccagatt gccaaggagc atgaatgcat gcggatcaag
961 atcctggggg actgttacta ctgtgtctct gggctgccac tctcactgcc agaccatgcc
1021 atcaactgcg tgcgcatggg cctggacatg tgccgggcca tcaggaaact gcgggcagcc
1081 actggcgtgg acatcaacat gcgtgtgggc gtgcactcag gcagcgtact gtgtggagtc
1141 atcgggctgc agaagtggca gtacgacgtt tggtcacatg atgtcacact ggctaaccac
1201 atggaggcag gcggtgtacc agggcgagtg cacatcacag gggctaccct ggccctgctg
1261 gcaggggctt atgctgtgga ggacgcaggc atggagcatc gggaccccta ccttcgggag
1321 ctaggggagc ctacctatct ggtcatcgat ccacgggcag aggaggagga tgagaagggc
1381 actgcaggag gcttgctgtc ctcgcttgag ggcctcaaga tgcgtccatc actgctgatg
1441 acccgttacc tggagtcctg gggcgcagcc aagccttttg cccacctgag ccacggagac
1501 agccctgtgt ccacctccac ccctctcccg gagaagaccc tggcttcctt cagcacccag
1561 tggagcctgg atcggagccg taccccccgg ggactagatg atgaactgga caccggggat
1621 gccaagttct tccaggtcat tgagcagctc aactcgcaga aacagtggaa gcagtcgaag
1681 gacttcaacc cactgacact gtacttcaga gagaaggaga tggagaaaga gtaccgactc
1741 tctgcaatcc ccgccttcaa atactatgaa gcctgcacct tcctggtttt tctctccaac
1801 ttcatcatcc agatgctagt gacaaacagg cccccagctc tggccatcac gtatagcatc
1861 accttcctcc tcttcctcct catccttttt gtctgcttct cagaggacct gatgaggtgt
1921 gtcctgaaag gccccaagat gctgcactgg ctgcctgcac tgtctggcct ggtggccaca
1981 cgaccaggac tgagaatagc cttgggcacc gccaccatcc tccttgtctt tgccatggcc
2041 attaccagcc tgttcttctt cccaacatca tcagactgcc ctttccaagc tcccaatgtg
2101 tcctccatga tttccaacct ctcctgggag ctccctgggt ctctgcctct catcagtgtc
2161 ccatactcca tgcactgctg cacgctgggc ttcctctcct gctccctctt tctgcacatg
2221 agcttcgagc tgaagctgct gctgctcctg ctgtggctgg cggcatcctg ctccctcttc
2281 ctgcactccc atgcctggct gtcggaatgc ctcatcgtcc gcctctatct gggccccttg
2341 gactccaggc ccggagtgct gaaggagccc aaactgatgg gtgctatctc cttcttcatc
2401 ttcttcttca ccctccttgt cctggctcgc cagaatgagt actactgccg cctggacttc
2461 ctgtggaaga agaagctgag gcaggagagg gaggagacag agacgatgga gaacctgact
2521 cggctgctct tggagaacgt gctccctgca cacgtggccc cccagttcat tggccagaac
2581 cggcgcaacg aggatctcta ccaccagtcc tatgaatgcg tttgtgtcct cttcgcctca
2641 gtcccagact tcaaggagtt ctactctgaa tccaacatca atcatgaggg cctagagtgt
2701 ctgaggctgc tcaatgagat aattgctgat tttgatgagc tgctctccaa gcccaagttc
2761 agtggggtgg agaagatcaa gaccatcggc agcacctaca tggcagccac aggcttaaat
2821 gccacctctg gacaggatgc acaacaggat gctgaacgga gctgcagcca ccttggcact
2881 atggtggaat ttgccgtggc cctggggtct aagctggacg tcatcaacaa gcattcattc
2941 aacaacttcc gcctgcgagt ggggttgaac catggacccg tagtagctgg agttattggg
3001 gcccagaagc cgcaatatga catttggggc aacacagtga acgtggccag ccgcatggag
3061 agtacaggag tccttggcaa aatccaagtg actgaggaga cagcatgggc cctacagtcc
3121 ctgggctaca cctgctacag ccggggtgtc atcaaggtga aaggcaaagg gcagctctgc
3181 acctacttcc tgaacacaga cttgacacga actggacctc cttcagctac cctaggctga
3241 gattgcactc gccttctaag aacctc
//