LOCUS AF494409 1729 bp mRNA linear HUM 29-JAN-2003
DEFINITION Homo sapiens pantothenate kinase 2 mRNA, complete cds.
ACCESSION AF494409
VERSION AF494409.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1729)
AUTHORS Hortnagel,K., Prokisch,H. and Meitinger,T.
TITLE An isoform of hPANK2, deficient in pantothenate kinase-associated
neurodegeneration, localizes to mitochondria
JOURNAL Hum. Mol. Genet. 12 (3), 321-327 (2003)
PUBMED 12554685
REFERENCE 2 (bases 1 to 1729)
AUTHORS Hoertnagel,K.
TITLE Complete coding sequence of human pantothenate kinase 2
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 1729)
AUTHORS Hoertnagel,K.
TITLE Direct Submission
JOURNAL Submitted (23-MAR-2002) Institute of Human Genetics, GSF Research
Center for Environment and Health, Ingolstaedter Landstrasse 1,
Neuherberg 85764, Germany
FEATURES Location/Qualifiers
source 1..1729
/db_xref="H-InvDB:HIT000080802"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="20"
/map="20p13-p12.3"
/tissue_type="brain"
CDS 7..1719
/note="PANK2"
/codon_start=1
/product="pantothenate kinase 2"
/protein_id="AAN32907.1"
/translation="MRRLGPFHPRVHWAAPPSLSSGLHRLLFLRGTRIPSSTTLSPPR
HDSLSLDGGTVNPPRVREPTGREAFGPSPASSDWLPARWRNGRGGRPRARLCSGWTAA
EEARRNPTLGGLLGRQRLLLRMGAGRLGAPMERHGRASATSVSSAGEQAAGDPEGRRQ
EPLRRRASSASVPAVGASAEGTRRDRLGSYSGPTSVSRQRVESLRKKRPLFPWFGLDI
GGTLVKLVYFEPKDITAEEEEEEVESLKSIRKYLTSNVAYGSTGIRDVHLELKDLTLC
GRKGNLHFIRFPTHDMPAFIQMGRDKNFSSLHTVFCATGGGAYKFEQDFLTIGDLQLC
KLDELDCLIKGILYIDSVGFNGRSQCYYFENPADSEKCQKLPFDLKNPYPLLLVNIGS
GVSILAVYSKDNYKRVTGTSLGGGTFFGLCCLLTGCTTFEEALEMASRGDSTKVDKLV
RDIYGGDYERFGLPGWAVASSFGNMMSKEKREAVSKEDLARATLITITNNIGSIARMC
ALNENINQVVFVGNFLRINTIAMRLLAYALDYWSKGQLKALFSEHEGYFGAVGALLEL
LKIP"
BASE COUNT 380 a 436 c 507 g 406 t
ORIGIN
1 gggtggatga ggaggctcgg gcccttccac ccacgcgtcc attgggcggc gccgccatca
61 ctctcttctg ggctacaccg ccttctcttc ctccgcggaa cccggatccc ctcctccacc
121 accctctccc cgccccgtca cgatagcctc tcattggacg gaggcacggt caatcctcct
181 cgagttaggg agccgactgg acgcgaggcc tttgggccgt ccccagcctc gtcggattgg
241 cttcctgcgc gttggcgcaa cggaagaggc ggccggccga gggcgcgcct ctgctctggc
301 tggaccgccg cggaggaggc gagaaggaat ccgacgctgg ggggcttgct cgggcggcag
361 cgactgctgc tgcggatggg agcgggccgg ctcggcgcgc ccatggagcg ccacggcagg
421 gcttccgcca cctccgtctc gtcggctggg gagcaggcgg ccggggaccc cgaagggcgg
481 cggcaggagc cactgcggcg ccgggcgagc agcgcgtcgg tgcccgcggt cggggcctcg
541 gctgagggca cgaggcggga tcgactgggc tcttacagcg gccccacctc ggtctcccgc
601 cagcgcgtcg aaagcctgag gaaaaagcgg ccgctttttc catggtttgg actggatatc
661 ggtggaactc tggtcaagct ggtatatttt gaacccaaag acatcactgc tgaagaagaa
721 gaggaagagg tggaaagtct taaaagtatt cggaagtacc tgacctccaa tgtggcttat
781 gggtctacag gcattcggga cgtgcacctc gagctgaagg acctgactct gtgtggacgc
841 aaaggcaatc tgcactttat acgctttccc actcatgaca tgcctgcttt tattcaaatg
901 ggcagagata aaaacttctc gagtctccac actgtctttt gtgccactgg aggtggagcg
961 tacaaatttg agcaggattt tctcacaata ggtgatcttc agctttgcaa actggatgaa
1021 ctagattgct tgatcaaagg aattttatac attgactcag tcggattcaa tggacggtca
1081 cagtgctatt actttgaaaa ccctgctgat tctgaaaagt gtcagaagtt accatttgat
1141 ttgaaaaatc cgtatcctct gcttctggtg aacattggct caggggttag catcttagca
1201 gtatattcca aagataatta caaacgggtc acaggtacta gtcttggagg aggaactttt
1261 tttggtctct gctgtcttct tactggctgt accacttttg aagaagctct tgaaatggca
1321 tctcgtggag atagcaccaa agtggataaa ctagtacgag atatttatgg aggggactat
1381 gagaggtttg gactgccagg ctgggctgtg gcttcaagct ttggaaacat gatgagcaag
1441 gagaagcgag aggctgtcag taaagaggac ctggccagag cgactttgat caccatcacc
1501 aacaacattg gctcaatagc aagaatgtgt gcccttaatg aaaacattaa ccaggtggta
1561 tttgttggaa atttcttgag aattaatacg atcgccatgc ggcttttggc atatgctttg
1621 gattattggt ccaaggggca gttgaaagca cttttttcgg aacacgaggg ttattttgga
1681 gctgttggag cactccttga gctgttgaag atcccgtgat cattacctg
//