LOCUS AF490936 339 bp mRNA linear HUM 24-JUL-2016 DEFINITION Homo sapiens isolate M-MAR-K4 nonfunctional immunoglobulin mRNA, partial sequence. ACCESSION AF490936 VERSION AF490936.2 KEYWORDS . SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 339) AUTHORS Abraham,R.S., Geyer,S.M., Price-Troska,T.L., Allmer,C., Kyle,R.A., Gertz,M.A. and Fonseca,R. TITLE Immunoglobulin light chain variable (V) region genes influence clinical presentation and outcome in light chain-associated amyloidosis (AL) JOURNAL Blood 101 (10), 3801-3808 (2003) PUBMED 12515719 REFERENCE 2 (bases 1 to 339) AUTHORS Abraham,R.S., Price-Troska,T.L. and Fonseca,R. TITLE Direct Submission JOURNAL Submitted (08-MAR-2002) Clinical Biochemistry and Immunology, Mayo Clinic, 200 1 St. SW, Rochester, MN 55905, USA REFERENCE 3 (bases 1 to 339) AUTHORS Abraham,R.S., Price-Troska,T.L. and Fonseca,R. TITLE Direct Submission JOURNAL Submitted (28-MAR-2003) Clinical Biochemistry and Immunology, Mayo Clinic, 200 1 St. SW, Rochester, MN 55905, USA REMARK Nucleotide sequence updated by database staff COMMENT On Mar 28, 2003 this sequence version replaced AF490936.1. FEATURES Location/Qualifiers source 1..339 /organism="Homo sapiens" /mol_type="mRNA" /isolate="M-MAR-K4" /db_xref="taxon:9606" /chromosome="2" /tissue_type="bone marrow" /note="from patient with primary amyloidosis" misc_feature <1..>339 /note="nonfunctional immunoglobulin light chain due to frameshift caused by rearrangement; VK4 family" BASE COUNT 78 a 95 c 83 g 81 t ORIGIN 1 ccctgggtgt gtctctgggc gagagggccc ctcaactgca agtccagcca gagtgtttta 61 tacagctcca acagnaagaa ctacttagct tggtaccagc agaaaccagg gcagtctcct 121 aaactactca tttactcggc atctacccgg gagtccgggg tccctgaccg attccgtggc 181 agcgggtctg ggacagattt cactctcacc atcaccagcc tgcaggctga agatgtggca 241 gtttattact gncagcaaca ttatagcact ccattcactt tcggccctgg gaccacagtg 301 gatatcaagc gaactgtggc tgcaccatgt gttttttaa //