LOCUS       AF490936                 339 bp    mRNA    linear   HUM 24-JUL-2016
DEFINITION  Homo sapiens isolate M-MAR-K4 nonfunctional immunoglobulin mRNA,
            partial sequence.
ACCESSION   AF490936
VERSION     AF490936.2
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Abraham,R.S., Geyer,S.M., Price-Troska,T.L., Allmer,C., Kyle,R.A.,
            Gertz,M.A. and Fonseca,R.
  TITLE     Immunoglobulin light chain variable (V) region genes influence
            clinical presentation and outcome in light chain-associated
            amyloidosis (AL)
  JOURNAL   Blood 101 (10), 3801-3808 (2003)
   PUBMED   12515719
REFERENCE   2  (bases 1 to 339)
  AUTHORS   Abraham,R.S., Price-Troska,T.L. and Fonseca,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-MAR-2002) Clinical Biochemistry and Immunology, Mayo
            Clinic, 200 1 St. SW, Rochester, MN 55905, USA
REFERENCE   3  (bases 1 to 339)
  AUTHORS   Abraham,R.S., Price-Troska,T.L. and Fonseca,R.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-MAR-2003) Clinical Biochemistry and Immunology, Mayo
            Clinic, 200 1 St. SW, Rochester, MN 55905, USA
  REMARK    Nucleotide sequence updated by database staff
COMMENT     On Mar 28, 2003 this sequence version replaced AF490936.1.
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /isolate="M-MAR-K4"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /tissue_type="bone marrow"
                     /note="from patient with primary amyloidosis"
     misc_feature    <1..>339
                     /note="nonfunctional immunoglobulin light chain due to
                     frameshift caused by rearrangement; VK4 family"
BASE COUNT           78 a           95 c           83 g           81 t
ORIGIN      
        1 ccctgggtgt gtctctgggc gagagggccc ctcaactgca agtccagcca gagtgtttta
       61 tacagctcca acagnaagaa ctacttagct tggtaccagc agaaaccagg gcagtctcct
      121 aaactactca tttactcggc atctacccgg gagtccgggg tccctgaccg attccgtggc
      181 agcgggtctg ggacagattt cactctcacc atcaccagcc tgcaggctga agatgtggca
      241 gtttattact gncagcaaca ttatagcact ccattcactt tcggccctgg gaccacagtg
      301 gatatcaagc gaactgtggc tgcaccatgt gttttttaa
//