LOCUS AF480466 7130 bp mRNA linear HUM 22-OCT-2002
DEFINITION Homo sapiens Rho-GTPase activating protein 10 (ARHGAP10) mRNA,
complete cds.
ACCESSION AF480466
VERSION AF480466.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7130)
AUTHORS Basseres,D.S., Tizzei,E.V., Duarte,A.A., Costa,F.F. and Saad,S.T.
TITLE ARHGAP10, a novel human gene coding for a potentially cytoskeletal
Rho-GTPase activating protein
JOURNAL Biochem. Biophys. Res. Commun. 294 (3), 579-585 (2002)
PUBMED 12056806
REFERENCE 2 (bases 1 to 7130)
AUTHORS Basseres,D.S., Tizzei,E.V., Costa,F.F. and Saad,S.T.O.
TITLE Direct Submission
JOURNAL Submitted (04-FEB-2002) Hematology and Hemotherapy Center, State
University of Campinas, Rua Carlos Chagas 480, Campinas, SP
13083-970, Brazil
FEATURES Location/Qualifiers
source 1..7130
/db_xref="H-InvDB:HIT000080456"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
/map="10p12.32"
/tissue_type="brain"
gene 1..7130
/gene="ARHGAP10"
CDS 438..6311
/gene="ARHGAP10"
/codon_start=1
/product="Rho-GTPase activating protein 10"
/protein_id="AAM22955.1"
/translation="MATRRTGLSEGDGDKLKACEVSKNKDGKEQSETVSLSEDETFSW
PGPKTVTLKRTSQGFGFTLRHFIVYPPESAIQFSYKDEENGNRGGKQRNRLEPMDTIF
VKQVKEGGPAFEAGLCTGDRIIKVNGESVIGKTYSQVIALIQNSDTTLELSVMPKDED
ILQVLQFTKDVTALAYSQDAYLKGNEAYSGNARNIPEPPPICYPWLPSAPSAMAQPVE
ISPPDSSLSKQQTSTPVLTQPGRAYRMEIQVPPSPTDVAKSNTAVCVCNESVRTVIVP
SEKVVDLLSNRNNHTGPSHRTEEVRYGVNEQTSLKTVSRTTSPPLSIPTTHLIHQPAG
SRSLEPSGILLKSGNYSGHSDGISSSRSQAVEAPSVSVNHYSPNSHQHIDWKNYKTYK
EYIDNRRLHIGCRTIQERLDSLRAASQSTTDYNQVVPNRTTLQGRRRSTSHDRVPQSV
QIRQRSVSQERLEDSVLMKYCPRSASQGALTSPSVSFSNHRTRSWDYIEGQDETLENV
NSGTPIPDSNGEKKQTYKWSGFTEQDDRRGICERPRQQEIHKSFRGSNFTVAPSVVNS
DNRRMSGRGVGSVSQFKKIPPDLKTLQSNRNFQTTCGMSLPRGISQDRSPLVKVRSNS
LKAPSTHVTKPSFSQKSFVSIKDQRPVNHLHQNSLLNQQTWVRTDSAPDQQVETGKSP
SLSGASAKPAPQSSENAGTSDLELPVSQRSQDLSLQEAETEQSDTLDNKEAVILREKP
PSGRQTPQPLRHQSYILAVNDQETGSDTTCWLPNDARREVHIKRMEERKASSTSPPGD
SLASIPFIDEPTSPSIDHDIAHIPASAVISASTSQVPSIATVPPCLTTSAPLIRRQLS
HDHESVGPPSLDAQPNSKTERSKSYDEGLDDYREDAKLSFKHVPSLKGIKIADSQKSS
EDSGSRKDSSSEVFSDAAKEGWLHFRPLVTDKGKRVGGSIRPWKQMYVVLRGHSLYLY
KDKREQTTPSEEEQPISVNACLIDISYSETKRKNVFRLTTSDCECLFQAEDRDDMLAW
IKTIQESSNLNEEDTGVTNRDLISRRIKEYNNLMSKAEQLPKTPRQSLSIRQTLLGAK
SEPKTQSPHSPKEESERKLLSKDDTSPPKDKGTWRKGIPSIMRKTFEKKPTATGTFGV
RLDDCPPAHTNRYIPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMAD
IDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLI
HDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHM
PDQYKIVETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIGRTGVSP
GDVSDSATSDSTKSKGSWGSGKDQYSRELLVSSIFAAASRKRKKPKEKAQPSSSEDEL
DNVFFKKENVEQCHNDTKEESKKESETLGRKQKIIIAKENSTRKDPSTTKDEKISLGK
ESTPSEEPSPPHNSKHNKSPTLSCRFAILKESPRSLLAQKSSHLEETGSDSGTLLSTS
SQASLARFSMKKSTSPETKHSEFLANVSTITSDYSTTSSATYLTSLDSSRLSPEVQSV
AESKGDEADDERSELISEGRPVETDSESEFPVFPTALTSERLFRGKLQEVTKSSRRNS
EGSELSCTEGSLTSSLDSRRQLFSSHKLIECDTLSRKKSARFKSDSGSLGDAKNEKEA
PSLTKVFDVMKKGKSTGSLLTPTRGESEKQEPTWKTKIADRLKLRPRAPADDMFGAGN
HKVNAETAKRKSIRRRHTLGGHRDATEISVLNFWKVHEQSGERESELSAVNRLKPKCS
AQDLSISDWLARERLRTSTSDLSRGEIGDPQTENPSTREIATTDTPLSLHCNTGSSSS
TLASTNRPLLSIPPQSPDQINGESFQNVSKNASSAANAQPHKLSETPGTKAEFHPCL"
BASE COUNT 2291 a 1609 c 1524 g 1706 t
ORIGIN
1 cgctgtcccg gagccggcca gccccgtgcg gatccactcg ccccgcttcc tctggatctc
61 tctaggagct gacactcgaa ccttcacgac ccattcggat ttttccagga ctcaggagtg
121 gcactgggaa gaaggggacc gctttctgca attggcctcg acactggctg ccaagaagac
181 ctgtcgcctt tgtttttaag tctccagaaa tggaagaaga aggcgaagtc agttgaagtc
241 acgagaaatc agcgaggcat ttgaaggcgc ttcctgaaaa cctttattcc ctggcacgtt
301 gtctgtttca acagccctgc ccctcctcgg agcctgcttg tggaattctt ccccttcggg
361 tgtgtggtgg cattccccgc cacgtccaat gtggactcca aaggatttgt cccttctttg
421 tcatttgaaa tgaaatgatg gccacgcgtc ggactggtct gtctgaggga gatggtgaca
481 agctcaaggc ctgcgaggtc tcaaaaaata aagatggaaa agaacaaagt gaaactgtat
541 cactgtctga agatgaaaca ttctcctggc caggtcccaa aacagttacg ttgaaaagaa
601 catctcaagg ctttggtttt acattaagac attttattgt ttatccccca gagtctgcaa
661 ttcaattttc atataaggat gaagaaaatg gaaacagagg aggaaaacaa agaaaccgct
721 tggaaccaat ggataccata tttgttaagc aagttaaaga aggaggacct gcttttgaag
781 ctggattatg tacaggtgac cgaattataa aagtcaatgg agaaagtgtt attggcaaaa
841 cctattccca agtaattgct ttaattcaaa acagtgatac aacattggaa cttagtgtta
901 tgccaaaaga tgaagacatt ctccaagtgc tacagtttac aaaggatgtc acagcactgg
961 catattctca agatgcctac ctgaaaggca acgaagctta tagcggcaat gcccgcaata
1021 tacctgaacc tccaccaatc tgctatccct ggctgccatc tgccccatca gccatggcac
1081 agccagttga aatatctcct cctgactcat cattgagcaa acagcaaacc agtacaccag
1141 tactgacaca acctggtagg gcctatagaa tggaaataca agtgcctcca tcaccaacag
1201 atgttgcaaa atcaaacaca gcagtgtgtg tttgcaatga aagtgtaagg actgtcattg
1261 tgccttctga gaaggttgta gatttgttat ccaatagaaa caaccataca ggtccttcac
1321 atagaactga agaagtgagg tatggcgtga atgagcagac ctctttaaaa acagtgtcaa
1381 gaaccacatc accaccatta tcaattccca ccactcatct aattcatcag cctgcaggct
1441 ccagatcact ggaaccttct ggaattttac ttaagtctgg aaattacagt ggacattctg
1501 atggaatctc aagcagcaga tctcaagctg tggaggctcc ctctgtatct gttaatcact
1561 attcgccaaa ttcccatcag cacatagact ggaaaaacta taaaacttac aaagagtata
1621 ttgataacag acgattgcac ataggttgtc ggacaataca agaaagatta gatagtttaa
1681 gagcagcatc tcaaagcacg acagattata accaggtcgt ccccaaccgc actactttgc
1741 agggacgacg tcgaagcacc tctcatgatc gagtgcccca gtctgtccag atacggcaac
1801 gcagtgtgtc ccaagaaaga ctggaagatt ctgtgctaat gaagtattgt ccaagaagtg
1861 catctcaagg agcactgacg tctccatctg ttagttttag taatcataga actcgttcat
1921 gggattatat tgagggacag gatgaaacct tagaaaatgt caattctgga actccaatac
1981 ctgattccaa tggagagaaa aaacagactt acaagtggag tgggtttact gaacaggatg
2041 atagacgagg tatttgtgaa agacctaggc agcaagaaat tcataaatct tttcgaggtt
2101 ccaattttac tgtggctcca agcgttgtta attctgataa caggcgaatg agtggtagag
2161 gagtgggatc tgtgtcgcag tttaaaaaaa ttccaccaga tctaaaaaca ttgcagtcaa
2221 acagaaattt tcagactact tgtggaatgt cactgcctcg gggtatttca caagacaggt
2281 cacctcttgt gaaagtccga agtaattctc tgaaagctcc ttccacgcat gtcacaaaac
2341 catcatttag ccagaaatca tttgtttcta tcaaagacca aagaccagta aatcacttgc
2401 atcagaacag tctgttgaat cagcagacat gggtaaggac tgacagtgcc cccgatcagc
2461 aagtggagac tgggaaatcc ccctctttat ctggagcctc tgccaagcct gcccctcagt
2521 cgagtgaaaa cgctggtact tcagatttag aactacctgt cagtcaaagg agtcaagatt
2581 taagtttaca agaggctgaa actgagcaat cagatacttt agataataaa gaagctgtca
2641 tcctaaggga aaaacctcca tctggacgcc agacaccgca gcctttaagg catcagtctt
2701 acatcttggc agtaaatgac caggagaccg ggtcagacac tacctgctgg ctgcccaatg
2761 atgcacgtcg agaggtccac ataaaaagaa tggaggaaag aaaagcctcg agtaccagtc
2821 cgcctggcga ttctttggct tccatcccat ttatagatga accaactagc cctagcattg
2881 atcatgatat tgcacatatc cctgcctctg ctgttatatc agcctctacc tctcaggtcc
2941 cctccatagc aacagttcct ccttgcctca caacttcagc tccattaatt cgccgtcagc
3001 tctcacatga ccacgaatct gttggccctc ctagcctgga tgctcagccc aactcaaaga
3061 cagaaagatc aaaatcatat gatgagggtc tggatgatta cagagaagat gcaaaattgt
3121 cctttaagca cgtacctagt ctgaagggaa tcaagatcgc agacagccaa aagtcatcag
3181 aagactctgg gtccagaaaa gattcttcct cagaggtctt cagtgatgct gccaaggaag
3241 ggtggcttca tttccgaccc cttgtcaccg ataagggcaa gcgagttggt ggaagtattc
3301 ggccatggaa acagatgtat gttgtccttc ggggtcattc actttacctg tacaaagata
3361 aaagagagca gacgactccg tctgaggaag agcagcccat cagtgttaat gcttgcttga
3421 tagacatctc ttacagtgag accaagagga aaaatgtgtt tcgactcacc acgtccgact
3481 gtgaatgcct gtttcaggct gaagacagag atgatatgct agcttggatc aagacgatcc
3541 aggagagcag caacctaaac gaagaggaca ctggagtcac taacagggat ctaattagtc
3601 gaagaataaa agaatacaac aatctgatga gcaaagcaga acagttgcca aaaacacctc
3661 gccagagtct cagcatcagg caaactttgc ttggtgctaa atcagagcca aagactcaaa
3721 gcccacactc tccgaaggaa gagtcggaaa ggaaacttct cagtaaagat gataccagtc
3781 ccccaaaaga caaaggcaca tggagaaaag gcattccaag tatcatgaga aagacatttg
3841 agaaaaagcc aactgctaca ggaactttcg gcgtccgact agatgactgc ccaccagctc
3901 atactaatcg gtatattcca ttaatagttg acatatgttg caaattagtt gaagaaagag
3961 gtcttgaata tacaggtatt tatagagttc ctggaaataa tgcagccatc tcaagtatgc
4021 aagaagaact caacaaggga atggctgata ttgatataca agatgataaa tggcgagatt
4081 tgaatgtgat aagcagttta ctaaaatcct tcttcagaaa actccctgag cctctcttca
4141 caaatgataa atatgctgat tttattgaag ccaatcgtaa agaagatcct ctagatcgtc
4201 tgaaaacatt aaaaagacta attcacgatt tgcctgaaca tcattatgaa acacttaagt
4261 tcctttcagc tcatctgaag acagtggcag aaaattcaga aaaaaataag atggaaccaa
4321 gaaacctagc aatagtgttt ggtcccaccc ttgttcgaac atcagaagac aacatgaccc
4381 acatggtcac ccacatgcct gaccagtaca agattgtaga aacgctcatc cagcaccatg
4441 actggttttt cacagaagaa ggtgctgaag agcctcttac aacagtgcag gaggaaagca
4501 cagtagactc ccagccagtg ccaaacatag atcatttact caccaacatt ggaaggacag
4561 gagtctcccc aggagatgta tcagattcag ctactagtga ctcaacaaaa tctaagggtt
4621 cttggggatc tggaaaggat cagtatagca gggaactgct tgtgtcctcc atctttgcag
4681 ctgctagtcg caagaggaag aagccgaaag aaaaagcaca gcctagcagc tcagaagatg
4741 aactggacaa tgtatttttt aagaaagaaa atgtggaaca gtgtcacaat gatactaaag
4801 aggagtccaa aaaagaaagt gagacactgg gcagaaaaca gaagatcatc attgccaaag
4861 aaaacagcac taggaaagac cccagcacga caaaagatga aaagatatca ctaggaaaag
4921 agagcacgcc ttctgaagaa ccctcaccac cacacaactc aaaacacaac aagtcaccaa
4981 ctctcagctg tcgctttgcc atcctgaaag agagccccag gtcacttctg gcacagaagt
5041 cctcccacct tgaagagaca ggctctgact ctggcacttt gctcagcacg tcttcccagg
5101 cctccctggc aaggttttcc atgaagaaat caaccagtcc agaaacgaaa catagcgagt
5161 ttttggccaa cgtcagcacc atcacctcag attattccac cacatcgtct gctacatact
5221 tgactagcct ggactccagt cgactgagcc ctgaggtgca atccgtggca gagagcaagg
5281 gggacgaggc agatgacgag agaagcgaac tcatcagtga agggcggcct gtggaaaccg
5341 acagcgagag cgagtttccc gtgttcccca cagccttgac ttcagagagg cttttccgag
5401 gaaaactgca agaagtgact aagagcagcc ggagaaattc tgaaggaagt gaattaagtt
5461 gcaccgaggg aagtttaaca tcaagtttag atagccggag acagctcttc agttcccata
5521 aactcatcga atgtgatact ctttccagga aaaaatcagc tagattcaag tcagatagtg
5581 gaagtctagg agatgccaag aatgagaaag aagcaccttc gttaactaaa gtgtttgatg
5641 ttatgaaaaa aggaaagtca actgggagtt tactgacacc caccagaggc gaatccgaaa
5701 aacaggaacc cacatggaaa acgaaaatag cagatcggtt aaaactgaga cccagagccc
5761 ctgcggatga catgtttgga gcagggaatc acaaagtgaa tgccgagact gctaaaagga
5821 aaagcatccg gcgcagacat acactaggag ggcacagaga tgctaccgaa atcagcgttt
5881 tgaatttttg gaaagtgcat gagcagagcg gggagagaga atctgaactt tcagctgtaa
5941 accggttaaa accaaaatgc tcagcccagg acctttccat ctcagactgg ctggccaggg
6001 aacgcctacg caccagtacc tctgacctta gcagaggaga aatcggagat ccccagacag
6061 agaacccaag cacacgagaa atagccacga ccgacacacc tttgtctctt cattgcaaca
6121 caggcagttc ttccagcacc ttggcttcaa caaacaggcc ccttctttcc ataccaccac
6181 agtcacctga ccaaataaac ggagaaagct tccagaacgt gagcaaaaat gctagttctg
6241 cagcgaatgc ccaacctcat aaactgtctg aaaccccagg cactaaagca gagtttcatc
6301 cctgtcttta aactgggggt atgtccactc tagcaagtaa aaaaactact gttacacgtt
6361 ccagtaactc tgtcaatatt ttcttgtatc agaattgtta ttatgcaggg ggcccccccc
6421 ccccttcatt tgggctggtt tcatcatttt gcactgtgaa atagctttac agtgcattac
6481 tacagccaga agaacatata tatatatata tatttaaaaa tatatcggat agttgtatac
6541 aaatgagcaa ggtatttgtt gcaacttact acatagcata tacccaaaat cactgaagaa
6601 aatcgctggc atcagtgtgc agcaaatttg ttcttttggt ttcatcacta acaaaagtgc
6661 ctcatcataa aaatacagtt ggtttttagg gtgccatatt gttaaaatta gataacttac
6721 ttacattgaa taaacgaatg cgttttattg gtaacagata tcattacatt taccagtttt
6781 aacacaggtg gatacagaac ttcccccaaa agtttttttt ttctttagtc attccaggtg
6841 gatctgagtt ttatattcaa acttttaata cagtttttga gttttgtgtg acttgaattt
6901 ttaatctttc tgtaaaatac gtaacttaaa tgaacatatt aaatgtgtat cttttcttca
6961 gataccagat ttgatataat gttgtaacat aggtgtgtag atagtggatc ctggatggaa
7021 ctggcttctt tatcgagaag aatataattc tgcatgagga cttaatgaat ccaaacctgt
7081 gtcatgcctg tgtgcatacc caattaaaca ctggaaataa aaaaaaaaaa
//