LOCUS AF480461 3884 bp mRNA linear HUM 15-APR-2002
DEFINITION Homo sapiens mixed lineage kinase-related kinase MRK-alpha mRNA,
complete cds.
ACCESSION AF480461
VERSION AF480461.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3884)
AUTHORS Gross,E.A., Callow,M.G., Waldbaum,L., Thomas,S. and Ruggieri,R.
TITLE MRK, a mixed lineage kinase-related molecule that plays a role in
gamma-radiation-induced cell cycle arrest
JOURNAL J. Biol. Chem. 277 (16), 13873-13882 (2002)
PUBMED 11836244
REFERENCE 2 (bases 1 to 3884)
AUTHORS Gross,E.A., Callow,M.G. and Ruggieri,R.
TITLE Direct Submission
JOURNAL Submitted (04-FEB-2002) North Shore-Long Island Jewish Research
Institute, 350 Community Drive, Manhasset, NY 11030, USA
FEATURES Location/Qualifiers
source 1..3884
/db_xref="H-InvDB:HIT000080454"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2q31"
CDS 196..2598
/codon_start=1
/product="mixed lineage kinase-related kinase MRK-alpha"
/protein_id="AAL85891.1"
/translation="MSSLGASFVQIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAV
KKLLKIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEM
DMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNH
TTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLV
VEKNERLTIPSSCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSF
LHNKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLPSF
EIGAWTEDDVYCWVQQLVRKGDSSAEMSVYASLFKENNITGKRLLLLEEEDLKDMGIV
SKGHIIHFKSAIEKLTHDYINLFHFPPLIKDSGGEPEENEEKIVNLELVFGFHLKPGT
GPQDCKWKMYMEMDGDEIAITYIKDVTFNTNLPDAEILKMTKPPFVMEKWIVGIAKSQ
TVECTVTYESDVRTPKSTKHVHLIQWSRTKPQDEVKAVQLAIQTLFTNSDGNPGSRSD
SSADCQWLDTLRMRQIASNTSLQRSQSNPILGSPFFSHFDGQDSYAAAVRRPQVPIKY
QQITPVNQSRSSSPTQYGLTKNFSSLHLNSRDSGFSSGNTDTSSERGRYSDRSRNKYG
RGSISLNSSPRGRYSGKSQHSTPSRGRYPGKFYRVSQSALNPHQSPDFKRSPRDLHQP
NTIPGMPLHPETDSRASEEDSKVSEGGWTKVEYRKKPHRPSPAKTNKERARGDHRGWR
NF"
BASE COUNT 1192 a 799 c 868 g 1025 t
ORIGIN
1 cttcctcatt ggcgccgtgc agagaggcgg aatgttcaac tcctaactgc ggcggaaacg
61 tgggagccgc gcgggccgct gtcgtcccaa cccccgccgc cctcgtcgcg cgcggggcct
121 ccgcgccccc ggctgctgct cacgccccgc ccgggagcca gattttgtgg aagtataata
181 ctttgtcatt atgagatgtc gtctctcggt gcctcctttg tgcaaattaa atttgatgac
241 ttgcagtttt ttgaaaactg cggtggagga agttttggga gtgtttatcg agccaaatgg
301 atatcacagg acaaggaggt ggctgtaaag aagctcctca aaatagagaa agaggcagaa
361 atactcagtg tcctcagtca cagaaacatc atccagtttt atggagtaat tcttgaacct
421 cccaactatg gcattgtcac agaatatgct tctctgggat cactctatga ttacattaac
481 agtaacagaa gtgaggagat ggatatggat cacattatga cctgggccac tgatgtagcc
541 aaaggaatgc attatttaca tatggaggct cctgtcaagg tgattcacag agacctcaag
601 tcaagaaacg ttgttatagc tgctgatgga gtactgaaga tctgtgactt tggtgcctct
661 cggttccata accatacaac acacatgtcc ttggttggaa ctttcccatg gatggctcca
721 gaagttatcc agagtctccc tgtgtcagaa acttgtgaca catattccta tggtgtggtt
781 ctctgggaga tgctaacaag ggaggtcccc tttaaaggtt tggaaggatt acaagtagct
841 tggcttgtag tggaaaaaaa cgagagatta accattccaa gcagttgccc cagaagtttt
901 gctgaactgt tacatcagtg ttgggaagct gatgccaaga aacggccatc attcaagcaa
961 atcatttcaa tcctggagtc catgtcaaat gacacgagcc ttcctgacaa gtgtaactca
1021 ttcctacaca acaaggcgga gtggaggtgc gaaattgagg caactcttga gaggctaaag
1081 aaactagagc gtgatctcag ctttaaggag caggagctta aagaacgaga aagacgttta
1141 aagatgtggg agcaaaagct gacagagcag tccaacaccc cgctgctgcc ttcctttgag
1201 attggtgcat ggacggaaga cgatgtgtat tgttgggttc agcagctcgt cagaaaaggt
1261 gactcttcag cagagatgag tgtatatgca agcttgttta aagaaaacaa cattacaggg
1321 aagcggctgc tgctgctgga ggaagaagac ctgaaagaca tgggcattgt ctccaagggg
1381 catatcattc acttcaagtc agccattgag aaattaaccc atgattacat aaatttgttt
1441 cacttcccac cactaattaa ggactcagga ggtgaacctg aagaaaatga ggaaaaaata
1501 gtgaacctgg aactggtttt tggttttcac ttgaaaccag gaactggccc acaggattgt
1561 aagtggaaaa tgtatatgga gatggatggg gatgaaattg caataaccta cataaaagat
1621 gtgacattca acactaacct acctgatgcg gagattttaa agatgacaaa gccaccattt
1681 gtaatggaga agtggattgt aggaatagca aaaagtcaga ctgtggagtg cactgtcaca
1741 tatgagagtg atgttagaac tccaaaaagc actaaacatg tccatttgat tcagtggagt
1801 agaacaaaac ctcaggatga agtgaaagca gtccaacttg ccattcagac attattcacc
1861 aattcagatg gcaaccctgg aagcaggtcc gactcaagtg ctgattgcca gtggttagat
1921 actctgagga tgcggcagat tgcatccaac acttctttac agcgttccca gagcaatcct
1981 attctggggt caccgttctt ctcacacttt gatggccagg attcctacgc tgctgctgtg
2041 agacggcccc aggtgcccat taagtatcaa cagattacac ctgtgaacca gtccagaagc
2101 tcgtctccta ctcagtatgg actgaccaaa aacttctctt ccctacatct caactctagg
2161 gacagtggct tttccagtgg caatactgac acctcttcag agaggggtcg atactcagac
2221 agaagcagga acaaatatgg acgtggtagt atatcactca attcttctcc tagaggaaga
2281 tacagtggaa agagtcagca ttccactcct tcaagaggaa gataccctgg aaagttctac
2341 agggtttctc agtcagcact caatcctcac cagtcgcctg acttcaagag aagccccagg
2401 gacctccacc aacccaacac cataccaggg atgcctttgc accctgagac tgactcaaga
2461 gccagtgaag aggacagcaa agtcagcgaa gggggctgga caaaagtgga ataccggaaa
2521 aagccccaca ggccatctcc cgccaaaacc aataaagaga gagccagagg ggaccaccgt
2581 ggatggagaa acttttgatg aattgaacta catagctttt ctaagcaggt taaaaaaaaa
2641 aaaaaaaaaa gaaatgtaat ggtttttgat aatatgatcc cttcagattg aattaacgaa
2701 aagacaacac ttccagtttt tggattggga aataccttct aattgagact atagccaaac
2761 cagggccaaa attatggata ttggtcaccc agtgatcata actaggcttg aaaatcacta
2821 cacatatttt ctgccttgag tgaacatttt tagaggaaag gttatgccat ctttttaccc
2881 taaccactga tattctggtt agcagggcca ggacaagggg aaggaaaatg aggtcaacaa
2941 aaaaatcaaa tttttaggaa aagataagat gaatgttact gatttttcct tttggctgag
3001 gctgcaatat ggcctggcaa ggcactgtta ctgatcttgt ctttaacatt ttgatatttt
3061 gttcatcata atttttgcat ttattttttt aaatattgca ttaaaatatc atttagcttg
3121 attatcgagt tttttggttt gaggtttttt gttgcttctt ttttcttttc tttctttccc
3181 cctctttttt ttggatgtcc ccttaaattt tgtgcccaag gcaggtacct cactcatctc
3241 atccttggct cagccctgct ggttagtatt tagtatttat tttagtaaga tatttgtgtc
3301 tgtatgatgg tcagagttga actgatctgg cttgtcattt ttcagtaata aaaaaagtta
3361 ctgaatttaa ttgttgaata tgatgcatat ctcattcatt acgatttatc agaaaccaaa
3421 gatttaaatt gcctagattt gtggttcttt ctcttcctaa gttcccagcg actgctttca
3481 aatactattt tctaaatttc accaaaggag caaagaggat aaaacaacgc tccataaagg
3541 cctcttggga tgtcagaaat ctaaaatcta aaagaaaaca gacacagagc aagacaataa
3601 catcacaagc taaaagccag agaaatttaa aattaccaac atccttgttg gagtaagaca
3661 gtaaatatca gccttgcagc aagacagctc tgagcagctg tgggcaaaga ggtaaaccag
3721 tgggggtgca aggagactgt ctgcagctta gggcagaaat ggggggatcc aacttgtgaa
3781 atgcttcatg ttttacaaac caaaaagtcg ggtagcaaca aacttattgt atgtcaaatc
3841 aataaatgtt actttcaata tccaaaaaaa aaaaaaaaaa aaaa
//