LOCUS AF480262 1342 bp mRNA linear HUM 09-SEP-2002
DEFINITION Homo sapiens mitochondrial thioredoxin mRNA, complete cds; nuclear
gene for mitochondrial product.
ACCESSION AF480262
VERSION AF480262.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1342)
AUTHORS Chen,Y., Cai,J., Murphy,T.J. and Jones,D.P.
TITLE Overexpressed human mitochondrial thioredoxin confers resistance to
oxidant-induced apoptosis in human osteosarcoma cells
JOURNAL J. Biol. Chem. 277 (36), 33242-33248 (2002)
PUBMED 12032145
REFERENCE 2 (bases 1 to 1342)
AUTHORS Chen,Y., Cai,J. and Jones,D.P.
TITLE Direct Submission
JOURNAL Submitted (01-FEB-2002) Department of Biochemistry, Emory
University, 1510 Clifton Road, Atlanta, GA 30322, USA
FEATURES Location/Qualifiers
source 1..1342
/db_xref="H-InvDB:HIT000080447"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="22"
/cell_line="143B osteosarcoma"
CDS 78..578
/note="mtTrx; Trx2"
/codon_start=1
/product="mitochondrial thioredoxin"
/protein_id="AAN05576.1"
/translation="MAQRLLLRRFLASVISRKPSQGQWPPLTSRALQTPQCSPGGLTV
TPNPARTIYTTRISLTTFNIQDGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEK
MVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAF
LKKLIG"
BASE COUNT 294 a 387 c 366 g 295 t
ORIGIN
1 gaggaagtga cgacaggcgt gcccttgaca ggcagggagg gctaggctgt gcatccctcc
61 gctcgcattg cagggagatg gctcagcgac ttcttctgag gaggttcctg gcctctgtca
121 tctccaggaa gccctctcag ggtcagtggc cacccctcac ttccagagcc ctgcagaccc
181 cacaatgcag tcctggtggc ctgactgtaa cacccaaccc agcccggaca atatacacca
241 cgaggatctc cttgacaacc tttaatatcc aggatggacc tgactttcaa gaccgagtgg
301 tcaacagtga gacaccagtg gttgtggatt tccacgcaca gtggtgtgga ccctgcaaga
361 tcctggggcc gaggttagag aagatggtgg ccaagcagca cgggaaggtg gtgatggcca
421 aggtggatat tgatgaccac acagacctcg ccattgagta tgaggtgtca gcggtgccca
481 ctgtgctggc catgaagaat ggggacgtgg tggacaagtt tgtgggcatc aaggatgagg
541 atcagttgga ggccttcctg aagaagctga ttggctgaca agcagggatg agtcctggtt
601 cccttgcccg cgtgggaccc caatagaact cagcccttcc atgccagccc ttcctgctgc
661 ctccctcctg tctggctcct ggggcccatg cttagagccc aggctccagc cctgagtgct
721 tccgagctgg cggactgccc aggggccatc agaggatggt ggtgctgctg ctgatccggg
781 gaccgctgtc ttccctccca tacgcctttc atccctcctt ctagggccta tggcagttct
841 cccaggatgt gtggcgagag cctgggccag cccacagcgt tcctagtcag gcagccacac
901 cttggtcctc atcttggtcc cttccaatct gaaacctcgt gcctggctcg tctgccacct
961 acatttctct ttccagctgc tgttttgtaa aaagaaaaag aaaaaagaag cccaaactag
1021 tgagagtaat atctaattat ctcatttttt gtaggtctgt gataaagaac ttagtcatcc
1081 cttccacctc ctactgtgaa gaacagaccc tgggtcccac actgaaatcc cctctagtca
1141 cccattccca ccccccaggg agctgcctcc caggcagggg gtgcagaaaa tgattgatgg
1201 gctggggaac cctggagagc ctcgactccg gaagtctcaa ggtgcctcct cctctcctta
1261 gctggcccgt tggttttctg agcagggggc tgaactgtga acaagtcaga caaataaagc
1321 aagggtctgc accatgaaaa aa
//