LOCUS AF479747 3368 bp mRNA linear HUM 12-AUG-2002
DEFINITION Homo sapiens PYRIN-containing APAF1-like protein 4 mRNA, complete
cds.
ACCESSION AF479747
VERSION AF479747.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3368)
AUTHORS Wang,L., Manji,G.A., Grenier,J.M., Al-Garawi,A., Merriam,S.,
Lora,J.M., Geddes,B.J., Briskin,M., DiStefano,P.S. and Bertin,J.
TITLE PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates
activation of NF-kappa B and caspase-1-dependent cytokine
processing
JOURNAL J. Biol. Chem. 277 (33), 29874-29880 (2002)
PUBMED 12019269
REFERENCE 2 (bases 1 to 3368)
AUTHORS Bertin,J.
TITLE Direct Submission
JOURNAL Submitted (01-FEB-2002) Inflammation, Millennium Pharmaceuticals
Inc., 45 Sidney Street, Cambridge, MA 02139, USA
FEATURES Location/Qualifiers
source 1..3368
/db_xref="H-InvDB:HIT000080437"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="19q13.4"
CDS 70..3054
/note="PYPAF4; PYRIN-containing nucleotide-binding
site/leucine-rich repeat family member"
/codon_start=1
/product="PYRIN-containing APAF1-like protein 4"
/protein_id="AAL87104.1"
/translation="MAASFFSDFGLMWYLEELKKEEFRKFKEHLKQMTLQLELKQIPW
TEVKKASREELANLLIKHYEEQQAWNITLRIFQKMDRKDLCMKVMRERTGYTKTYQAH
AKQKFSRLWSSKSVTEIHLYFEEEVKQEECDHLDRLFAPKETGKQPRTVIIQGPQGIG
KTTLLMKLMMAWSDNKIFRDRFLYTFYFCCRELRELPPTSLADLISREWPDPAAPITE
IVSQPERLLFVIDSFEELQGGLNEPDSDLCGDLMEKRPVQVLLSSLLRKKMLPEASLL
IAIKPVCPKELRDQVTISEIYQPRGFNESDRLVYFCCFFKDPKRAMEAFNLVRESEQL
FSICQIPLLCWILCTSLKQEMQKGKDLALTCQSTTSVYSSFVFNLFTPEGAEGPTPQT
QHQLKALCSLAAEGMWTDTFEFCEDDLRRNGVVDADIPALLGTKILLKYGERESSYVF
LHVCIQEFCAALFYLLKSHLDHPHPAVRCVQELLVANFEKARRAHWIFLGCFLTGLLN
KKEQEKLDAFFGFQLSQEIKQQIHQCLKSLGERGNPQGQVDSLAIFYCLFEMQDPAFV
KQAVNLLQEANFHIIDNVDLVVSAYCLKYCSSLRKLCFSVQNVFKKEDEHSSTSDYSL
ICWHHICSVLTTSGHLRELQVQDSTLSESTFVTWCNQLRHPSCRLQKLGINNVSFSGQ
SVLLFEVLFYQPDLKYLSFTLTKLSRDDIRSLCDALNYPAGNVKELALVNCHLSPIDC
EVLAGLLTNNKKLTYLNVSCNQLDTGVPLLCEALCSPDTVLVYLMLAFCHLSEQCCEY
ISEMLLRNKSVRYLDLSANVLKDEGLKTLCEALKHPDCCLDSLCLVKCFITAAGCEDL
ASALISNQNLKILQIGCNEIGDVGVQLLCRALTHTDCRLEILGLEECGLTSTCCKDLA
SVLTCSKTLQQLNLTLNTLDHTGVVVLCEALRHPECALQVLGLRKTDFDEETQALLTA
EEERNPNLTITDDCDTITRVEI"
BASE COUNT 900 a 803 c 828 g 837 t
ORIGIN
1 ggcacgagga tttatttatt gttcctggtc actgtctctt tgaggattgg tatctctgct
61 ccagaaaaga tggcagcctc tttcttctct gattttggtc ttatgtggta tctggaggag
121 ctcaaaaagg aggagttcag gaaatttaaa gaacatctca agcaaatgac tttgcagctt
181 gaactcaagc agattccctg gactgaggtc aaaaaagcat cccgggaaga acttgcaaac
241 ctcttgatca agcactatga agaacaacaa gcttggaaca taaccttaag aatctttcaa
301 aagatggata gaaaggatct ctgcatgaag gtcatgaggg agagaacagg atacacaaag
361 acctatcaag ctcacgcaaa gcagaaattc agccgcttat ggtccagcaa gtctgtcact
421 gagattcacc tatactttga ggaggaagtc aagcaagaag aatgtgacca tttggaccgc
481 ctttttgctc ccaaggaaac tgggaaacag ccacgtacag tgattattca aggaccacaa
541 ggaattggaa aaacgacact cctgatgaag ctgatgatgg cctggtcgga caacaagatc
601 tttcgggata ggttcctgta cacgttctat ttctgctgca gagaactgag ggagttgccg
661 ccaacgagtt tggctgactt gatttccaga gagtggcctg accccgctgc tcctataaca
721 gagatcgtgt ctcaaccgga gagactcttg ttcgtcatcg acagcttcga agagctgcag
781 ggcggcttga acgaacccga ttcggatctg tgtggtgact tgatggagaa acggccggtg
841 caggtgcttc tgagcagttt gctgaggaag aagatgctcc cggaggcctc cctgctcatc
901 gccatcaaac ccgtgtgccc gaaggagctc cgggatcagg tgacgatctc agaaatctac
961 cagccccggg gattcaacga gagtgatagg ttagtgtatt tctgctgttt cttcaaagac
1021 ccgaaaagag ccatggaagc cttcaatctt gtaagagaaa gtgaacagct gttttccata
1081 tgccaaatcc cgctcctctg ctggatcctg tgtaccagtc tgaagcaaga gatgcagaaa
1141 ggaaaagacc tggccctgac ctgccagagc actacctctg tgtactcctc tttcgtcttt
1201 aacctgttca cacctgaggg tgccgagggc ccgactccgc aaacccagca ccagctgaag
1261 gccctgtgct ccctggctgc agagggtatg tggacagaca catttgagtt ttgtgaagac
1321 gacctccgga gaaatggggt tgttgacgct gacatccctg cgctgctggg caccaagata
1381 cttctgaagt acggggagcg tgagagctcc tacgtgttcc tccacgtgtg tatccaggag
1441 ttctgtgccg ccttgttcta tttgctcaag agccaccttg atcatcctca cccagctgtg
1501 agatgtgtac aggaattgct agttgccaat tttgaaaaag caaggagagc acattggatt
1561 tttttggggt gttttctaac tggcctttta aataaaaagg aacaagaaaa actggatgcg
1621 ttttttggct tccaactgtc ccaagagata aagcagcaaa ttcaccagtg cctgaagagc
1681 ttaggggagc gtggcaatcc tcagggacag gtggattcct tggcgatatt ttactgtctc
1741 tttgaaatgc aggatcctgc ctttgtgaag caggcagtga acctcctcca agaagctaac
1801 tttcatatta ttgacaacgt ggacttggtg gtttctgcct actgcttaaa atactgctcc
1861 agcttgagga aactctgttt ttccgttcaa aatgtcttta agaaagagga tgaacacagc
1921 tctacgtcgg attacagcct catctgttgg catcacatct gctctgtgct caccaccagc
1981 gggcacctca gagagctcca ggtgcaggac agcaccctca gcgagtcgac ctttgtgacc
2041 tggtgtaacc agctgaggca tcccagctgt cgccttcaga agcttggaat aaataacgtt
2101 tccttttctg gccagagtgt tctgctcttt gaggtgctct tttatcagcc agacttgaaa
2161 tacctgagct tcaccctcac gaaactctct cgtgatgaca tcaggtccct ctgtgatgcc
2221 ttgaactacc cagcaggcaa cgtcaaagag ctagcgctgg taaattgtca cctctcaccc
2281 attgattgtg aagtccttgc tggccttcta accaacaaca agaagctgac gtatctgaat
2341 gtatcctgca accagttaga cacaggcgtg ccccttttgt gtgaagccct gtgcagccca
2401 gacacggtcc tggtatacct gatgttggct ttctgccacc tcagcgagca gtgctgcgaa
2461 tacatctctg aaatgcttct gcgtaacaag agcgtgcgct atctagacct cagtgccaat
2521 gtcctgaagg acgaaggact gaaaactctc tgcgaggcct tgaaacatcc ggactgctgc
2581 ctggattcac tgtgtttggt aaaatgtttt atcactgctg ctggctgtga agacctcgcc
2641 tctgctctca tcagcaatca aaacctgaag attctgcaaa ttgggtgcaa tgaaatcgga
2701 gatgtgggtg tgcagctgtt gtgtcgggct ctgacgcata cggattgccg cttagagatt
2761 cttgggttgg aagaatgtgg gttaacgagc acctgctgta aggatctcgc gtctgttctc
2821 acctgcagta agaccctgca gcagctcaac ctgaccttga acaccttgga ccacacaggg
2881 gtggttgtac tctgtgaggc cctgagacac ccagagtgtg ccctgcaggt gctcgggctg
2941 agaaaaactg attttgatga ggaaacccag gcacttctga cggctgagga agagagaaat
3001 cctaacctga ccatcacaga tgactgtgac acaatcacaa gggtagagat ctgattgcga
3061 ggaacctggg ctctgactcg aacacctgca aaggacaggg actgggaccg ttacttacat
3121 gacactgcac ccaggagata caaatcattg acactctgag ttgtgagatt tctggcaccc
3181 cattcataga tttgatatga tacacgtggt ttttatgtgc tctgtggcct tggatgagtc
3241 actgaaaggc cttcatggtc tctcggtctc acaaggacct cttaacccct caataaagtg
3301 ttacatttct aaacattgga aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3361 aaaaaaaa
//