LOCUS AF466375 1732 bp mRNA linear HUM 08-JUL-2002
DEFINITION Homo sapiens sphingolipid delta 4 desaturase protein DES1 mRNA,
complete cds.
ACCESSION AF466375
VERSION AF466375.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1732)
AUTHORS Ternes,P., Franke,S., Zahringer,U., Sperling,P. and Heinz,E.
TITLE Identification and characterization of a sphingolipid delta
4-desaturase family
JOURNAL J. Biol. Chem. 277 (28), 25512-25518 (2002)
PUBMED 11937514
REFERENCE 2 (bases 1 to 1732)
AUTHORS Ternes,P., Franke,S., Zaehringer,U., Sperling,P. and Heinz,E.
TITLE Direct Submission
JOURNAL Submitted (08-JAN-2002) Institut fuer Allgemeine Botanik,
Universitaet Hamburg, Ohnhorststr. 18, D-22609 Hamburg, Germany
FEATURES Location/Qualifiers
source 1..1732
/db_xref="H-InvDB:HIT000080335"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:2578328"
/sex="male"
/tissue_type="lung"
/dev_stage="fetal; 14 wk post-conception"
CDS 81..1052
/note="dihydroceramide desaturase; MLD protein"
/codon_start=1
/product="sphingolipid delta 4 desaturase protein DES1"
/protein_id="AAM12531.1"
/translation="MGSRVSREDFEWVYTDQPHADRRREILAKYPEIKSLMKPDPNLI
WIIIMMVLTQLGAFYIVKDLDWKWVIFGAYAFGSCINHSMTLAIHEIAHNAAFGNCKA
MWNRWFGMFANLPIGIPYSISFKRYHMDHHRYLGADGVDVDIPTDFEGWFFCTAFRKF
IWVILQPLFYAFRPLFINPKPITYLEVINTVAQVTFDILIYYFLGIKSLVYMLAASLL
GLGLHPISGHFIAEHYMFLKGHETYSYYGPLNLLTFNVGYHNEHHDFPNIPGKSLPLV
RKIAAEYYDNLPHYNSWIKVLYDFVMDDTISPYSRMKRHQKGEMVLE"
BASE COUNT 479 a 384 c 381 g 488 t
ORIGIN
1 gccgccgccg ccgccgccac ctctgagcag ccggctggga gcgagagccg acagctagtc
61 tgcaagccac cgctgtcgcc atggggagcc gcgtctcgcg ggaagacttc gagtgggtct
121 acaccgacca gccgcacgcc gaccggcgcc gggagatcct ggcaaagtat ccagagataa
181 agtccttgat gaaacctgat cccaatttga tatggattat aattatgatg gttctcaccc
241 agttgggtgc attttacata gtaaaagact tggactggaa atgggtcata tttggggcct
301 atgcgtttgg cagttgcatt aaccactcaa tgactctggc tattcatgag attgcccaca
361 atgctgcctt tggcaactgc aaagcaatgt ggaatcgctg gtttggaatg tttgctaatc
421 ttcctattgg gattccatat tcaatttcct ttaagaggta tcacatggat catcatcggt
481 accttggagc tgatggcgtc gatgtagata ttcctaccga ttttgagggc tggttcttct
541 gtaccgcttt cagaaagttt atatgggtta ttcttcagcc tctcttttat gcctttcgac
601 ctctgttcat caaccccaaa ccaattacgt atctggaagt tatcaatacc gtggcacagg
661 tcacttttga cattttaatt tattactttt tgggaattaa atccttagtc tacatgttgg
721 cagcatcttt acttggcctg ggtttgcacc caatttctgg acattttata gctgagcatt
781 acatgttctt aaagggtcat gaaacttact catattatgg gcctctgaat ttacttacct
841 tcaatgtggg ttatcataat gaacatcatg atttccccaa cattcctgga aaaagtcttc
901 cactggtgag gaaaatagca gctgaatact atgacaacct ccctcactac aattcctgga
961 taaaagtact gtatgatttt gtgatggatg atacaataag tccctactca agaatgaaga
1021 ggcaccaaaa aggagagatg gtgctggagt aaatatcatt agtgccaaag ggattcttct
1081 ccaaaacttt agatgataaa atggaatttt tgcattatta aacttgagac cagtgatgct
1141 cagaagctcc cctggcacaa tttcagagta agagctcggt gataccaaga agtgaatctg
1201 gcttttaaac agtcagcctg actctgtact gctcagtttc actcacagga aacttgtgac
1261 ttgtgtatta tcgtcattga ggatgtttca ctcatgtctg tcattttata agcatatcat
1321 ttaaaaagct tctaaaaagc tatttcgcca ggcacggtgg ctcatgccta taatcccagc
1381 actttgggag gccaaggtgg gtggatcacc tgaggtcagg agttcgagac cagcctggcc
1441 aacacggtga aaccccatct ctactaaaaa tgcaaaaatt agccgggcgt ggcggcacat
1501 gcctgtaatc ccagctacat gggaggctga ggtgggagaa ttgcttgaac ccaggaggcg
1561 gaggcagagg ctgcagtgac ccaagattgt gccactgcac tccaccctgg gcaacagagc
1621 aagaccccat ctcaaaaata aataaatata tataaaaaat aaaaagctat ttctagttta
1681 tttcactata aagttttgct ttattaaaaa gctaataaac agctattaat cc
//