LOCUS AF466143 7625 bp mRNA linear HUM 27-MAR-2002
DEFINITION Homo sapiens retinoic acid inducible in neuroblastoma cells RAINB1
mRNA, complete cds.
ACCESSION AF466143
VERSION AF466143.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7625)
AUTHORS Merrill,R.A., Plum,L.A., Kaiser,M.E. and Clagett-Dame,M.
TITLE A mammalian homolog of unc-53 is regulated by all-trans retinoic
acid in neuroblastoma cells and embryos
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (6), 3422-3427 (2002)
PUBMED 11904404
REFERENCE 2 (bases 1 to 7625)
AUTHORS Merrill,R.A., Plum,L.A., Kaiser,M.E. and Clagett-Dame,M.
TITLE Direct Submission
JOURNAL Submitted (08-JAN-2002) Biochemistry, University of Wisconsin -
Madison, 433 Babcock Dr., Madison, WI 53706, USA
FEATURES Location/Qualifiers
source 1..7625
/db_xref="H-InvDB:HIT000080324"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="11"
/cell_line="SH-SY5Y"
/cell_type="neuroblastoma"
CDS 77..7366
/note="similar to unc-53"
/codon_start=1
/product="retinoic acid inducible in neuroblastoma cells
RAINB1"
/protein_id="AAL96479.1"
/translation="MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSK
VEVSKTTYPSQIPLKSQVLQGLQEPAGEGLPLRKSGSVENGFDTQIYTDWANHYLAKS
GHKRLIRDLQQDVTDGVLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAK
GINIQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQPQKQHLSSPLPPAVSQVAGAPS
QCQAGTPQQQVPVTPQAPCQPHQPAPHQQSKAQAEMQSRLPGPTARVSAAGSEAKTRG
GSTTANNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESG
SSSTPTNCSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMK
PAPNNQKSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLT
TVGPASSSPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREKDKEKSKDLAKRA
SVTERLDLKEEPKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPK
PGMKSMPGKSPSAPAPSKEGERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGP
GGTTLNHSISSQTVSGSVGTTQTTGSNTVSVQLPQPQQQYNHPNTATVAPFLYRSQTD
TEGNVTAESSSTGVSVEPSHFTKTGQPALEELTGEDPEARRLRTVKNIADLRQNLEET
MSSLRGTQVTHSTLETTFDTNVTTEMSGRSILSLTGRPTPLSWRLGQSSPRLQAGDAP
SMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEGI
SMDAPGYMSDGDVLSKNIRTDDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNT
SLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLDVQTDA
EKHSQVERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPV
ISQTGSWRRGMTAQVGITMPRTKASAPAGALKTPGTGKTDDAKVSEKGRLSPKASQVK
RSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSGSAAGLAMITASGVTVTSRS
ATLGKIPKSSALVSRSAGRKSSMDGAQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNG
AGNRSSTSSIDSNISSKSAGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESV
ASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMK
NSVVISNPHATMTQQGNLDSPSGSGVLSSGSSSPLYSKNVDLNQSPLASSPSSAHSAP
SNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASS
KDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLR
YTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTT
VTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEE
VHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAF
EQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCK
GNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIESDSKKKKRKNWLRSSFKQAF
GKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEA
ETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSE
SQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDMLLDDTGECSARKEGGRHV
KIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQL
GLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFES
LIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFN
VDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCKYHK
CPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVR
NMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYS
IIPYLLEAVREGLQLYGRRAPWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFD
GYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILD
SSLESTL"
BASE COUNT 1923 a 2316 c 1996 g 1390 t
ORIGIN
1 acccgcgctg cctttagcgg tcgcccccgc cgccgctgcc agggacgtgc tgggaaagcc
61 caagccccgg gagaagatgc cggccatcct ggtcgcctcc aaaatgaagt cgggactgcc
121 caaacccgtg cacagcgccg cgcccatcct gcacgtgccc ccggcccggg cgggccccca
181 gccctgctac ctgaagttgg gaagcaaggt ggaggtgagc aagaccacct atcctagcca
241 gatccccctg aaatcgcagg tgctgcaggg gctgcaggag ccagcggggg aggggctccc
301 gctgcggaag agcggctcgg tggaaaacgg gttcgatacc cagatctaca cagactgggc
361 caatcattac ctagccaaat ccggccacaa gcgtctcatc agggatctcc agcaagatgt
421 gacagatggc gtcctcctgg cccagattat ccaggttgtg gcaaatgaaa agattgaaga
481 catcaatggc tgtccgaaga acagatccca aatgattgaa aacatagatg cctgcttgaa
541 tttcctggca gctaagggaa taaacatcca ggggctgtct gcagaagaga tcaggaatgg
601 aaacctcaag gccattctag gcctcttctt cagcctctcc cgatacaagc agcagcagca
661 gcagccccag aagcagcacc tctcctcacc tctgccgccc gccgtatccc aggtggccgg
721 ggccccctcc cagtgccagg ctggcacccc tcagcagcag gtgccagtca ctccccaagc
781 cccgtgccag cctcaccagc cagcgccaca tcagcagtca aaagcacaag ctgaaatgca
841 gtccagactt ccaggtccta ccgcgagggt atccgctgca ggcagcgagg ccaaaacacg
901 cggagggtca actactgcta acaaccgacg cagccagagc tttaacaact atgataaatc
961 caaaccagtc acctccccac ccccaccgcc aagcagccac gagaaagagc ctttggcaag
1021 ttcagcctcc tcccaccccg gaatgagtga caatgcacct gcttccttgg agagcggcag
1081 cagctccacc cctactaatt gcagtacctc ctcggccatc ccgcagcccg gtgcagccac
1141 caagccttgg cgcagcaaat ccctcagcgt gaagcacagt gccacggtat ccatgctctc
1201 ggtcaagcct cctgggcctg aggcccccag gcccacacct gaagccatga agccggcccc
1261 caacaatcag aagtccatgc tggaaaagct gaaacttttc aacagtaaag ggggctcaaa
1321 ggcaggtgag gggccggggt cccgggacac aagctgtgag cggctggaga ctctgcccag
1381 cttcgaagag agcgaggagc tggaggccgc cagtcgcatg ctcaccaccg tgggccctgc
1441 ttccagcagc cccaagattg cactcaaggg cattgcccag aggactttta gccgggcact
1501 gaccaacaag aagagttctc tgaaaggcaa tgagaaagag aaggagaaac aacagcggga
1561 gaaggataag gagaaaagca aggaccttgc caagagagcc tctgtgacgg agaggctgga
1621 cctcaaggag gagccaaaag aagaccccag tggagcagct gtgcccgaga tgccaaaaaa
1681 gtcctccaag attgccagct tcatccccaa aggggggaag ctcaacagtg ccaagaagga
1741 gcccatggcc ccttcccaca gtggaatacc aaaaccagga atgaagagca tgcccgggaa
1801 atccccaagt gccccagcgc cttccaagga aggggagcgg agccggagtg ggaagctgag
1861 ctcaggactc ccccagcaga agccccagct ggacggcaga cactccagtt cctcttccag
1921 cctggcgtcc tcagaaggaa aaggcccagg agggaccacc ctgaaccaca gcatcagcag
1981 ccagactgtc agtgggtctg tcgggaccac ccagaccaca ggaagcaata ccgtcagtgt
2041 tcagctacct cagccccagc agcaatacaa ccatcccaac actgccacgg ttgcaccttt
2101 cctgtacagg tctcagacgg acactgaagg gaatgttact gccgagtcaa gctcaacagg
2161 tgtgagcgtg gagcccagcc acttcaccaa gactggacag cctgctctgg aagaactcac
2221 tggggaagat cctgaggctc ggcggctgcg gacagtgaag aacatcgctg atctgcggca
2281 gaatttggag gaaaccatgt ccagtttaag gggaactcag gttacacaca gcacattgga
2341 aaccacgttt gacaccaatg tcaccacgga gatgagtggc cgtagcatac tcagcttgac
2401 agggaggccc acacctctgt cctggagact gggccagtcc agccctcggc tccaagcagg
2461 agacgccccc tcaatgggca atgggtatcc ccctcgagcc aacgccagca ggttcatcaa
2521 cactgagtca ggtcgctatg tgtactccgc ccctctgaga aggcagctgg cctcccgggg
2581 cagtagtgtc tgccacgtgg acgtctcaga caaggcagga gatgagatgg acctggaagg
2641 catcagcatg gacgcccccg gctacatgag cgatggggat gttctgagca agaacatccg
2701 gaccgatgac attacaagcg gatacatgac tgatggtgga cttggcctct atacccgtcg
2761 cctgaaccgg ctccctgatg ggatggctgt ggtacgggag accctgcaac gaaatacctc
2821 cctgggcctc ggagacgctg acagctggga cgacagcagc tccgtcagca gcggcatcag
2881 cgacaccata gacaacctca gcactgatga catcaacacc agctcctcca tcagctctta
2941 tgccaacaca cctgcctcct ctcgaaaaaa cctggatgtg cagactgatg ctgagaagca
3001 ctcacaggtg gagaggaatt ccctgtggtc tggtgatgat gtcaagaaat cagacggagg
3061 ctcagacagc ggcataaaaa tggagccagg ttccaagtgg aggcggaatc cttctgatgt
3121 gtctgacgag tccgacaaaa gcacgtcggg caagaagaat cctgtcatct cccagacagg
3181 ctcatggcgg cgaggcatga cagctcaggt gggcatcacc atgccaagga cgaaggcttc
3241 agccccggca ggcgcactga agaccccagg aactggaaaa acagacgacg caaaggtgtc
3301 tgagaaagga aggctttctc ctaaagcctc ccaggtgaag cgctccccat cagatgcagg
3361 ccggagcagt ggtgacgaat ccaaaaagcc cctccccagc agctctagga cacctactgc
3421 caatgccaac agctttgggt tcaagaagca gagtggttcc gccgccggcc tggccatgat
3481 cacagccagc ggggtgactg tcaccagcag gtcagccaca ctgggcaaaa tcccaaagtc
3541 atctgcactc gtcagtcggt ctgctggtcg gaagtcaagt atggatgggg ctcagaatca
3601 ggatgacggg tatctagccc taagctcccg gacaaacctt cagtaccgga gtttgccgag
3661 gcccagtaag tccaacagcc ggaacggggc tgggaacagg tctagcacca gcagcataga
3721 ttccaacatt agcagcaagt ccgcaggcct gccagtgccc aaactgaggg agccttccaa
3781 aacagcccta ggcagctctc taccaggtct ggtcaaccaa acagataagg agaaaggcat
3841 ctcatcagac aacgagagtg tggcttcctg taactcggtg aaagtgaatc cggcagccca
3901 gcctgtgtcc agtccggctc agaccagtct ccagcctgga gccaagtacc cagatgtggc
3961 ctctcccaca ctccgcagac tctttggtgg gaagcctacc aagcaagtgc ccatcgccac
4021 agctgaaaac atgaaaaatt cggtggtcat ctccaatcct catgccacca tgactcagca
4081 aggtaaccta gactccccgt caggcagtgg cgtcctgagc agtgggagca gcagtcctct
4141 ctacagcaag aatgtggacc tcaaccagtc tccgctagcc tccagcccca gctcagccca
4201 ctcggcccct tccaacagcc tcacctgggg caccaacgcc agcagctcct ccgcagttag
4261 caaggatggc ctgggctttc agtctgtcag cagcctccac accagctgtg agtccatcga
4321 catctccctc agcagtggag gggtccccag ccacaattct tccactggcc tcatcgcctc
4381 ctccaaggac gactccttga ctccctttgt cagaactaac agtgtgaaga ccacactgtc
4441 agaaagccct ctctcttccc ctgctgctag ccctaagttc tgcagaagta ctctgcccag
4501 gaaacaggac agtgacccgc accttgatag gaacactttg cctaagaaag gactcaggta
4561 tactcccacc tcccagcttc gcacgcaaga agatgcaaaa gaatggttac ggtcccattc
4621 tgcaggaggc cttcaggaca ccgctgccaa ttcccccttt tcctctggct ccagcgtgac
4681 ttctccctcc ggaacaagat tcaacttttc ccagcttgcg agtcccacca ctgtcaccca
4741 gatgagcttg tccaacccga ccatgctgag gactcacagc ctctccaatg ctgatgggca
4801 gtatgatcca tacactgaca gccgcttccg gaatagctcc atgtccctgg atgagaagag
4861 cagaaccatg agccgttcag gctcattccg ggatgggttt gaagaagttc atggatcctc
4921 actctccttg gtttccagca catcgtcagt ttattctaca ccagaagaaa aatgccagtc
4981 agagattcgc aagctgcggc gggaactgga tgcctcccag gagaaagttt cagctttgac
5041 cacccagctg acagcaaatg ctcaccttgt ggcagccttt gaacagagtc ttggtaacat
5101 gacaatcagg ctccagagtc tgaccatgac agctgagcag aaggactcag aactgaatga
5161 gttaagaaaa accattgagc tgctaaagaa acagaacgca gctgcccagg ctgccattaa
5221 tggagtaatt aacacacctg agctcaactg caaaggaaac ggcactgccc agtctgcaga
5281 cctccgcatc cgcaggcagc actcctcaga cagcgtctcc agcatcaaca gtgccaccag
5341 ccactccagc gtgggcagca acatagagag tgactcaaag aagaagaagc ggaagaactg
5401 gttacgcagc tccttcaagc aagctttcgg gaagaagaag tccccaaaat ctgcgtcctc
5461 tcattcagat attgaggaga tgacggattc ttctttgcct tcctcaccaa agttaccgca
5521 caatgggtcc acaggttcca ccccactgct gaggaattct cactccaact ctctaatttc
5581 agaatgcatg gatagtgaag ctgagaccgt catgcagctc cgaaatgagt taagagacaa
5641 ggagatgaag ctgacggata tccgcttaga agctctcagt tctgcccacc agctggacca
5701 gctccgggag gccatgaaca ggatgcagag tgaaatagag aagctgaaag ctgagaatga
5761 tcggctgaag tcagagtctc aaggcagtgg ctgcagccgg gctccttccc aagtgtccat
5821 ctctgcctcc ccgaggcagt ccatgggcct ctcccagcac agcttgaacc tcactgagtc
5881 aaccagcctg gacatgttgc tggatgacac tggtgaatgc tcggctcgga aggaaggagg
5941 caggcatgtt aagatagttg tcagctttca ggaggaaatg aagtggaagg aggattccag
6001 accacatctc tttcttattg gctgcattgg agttagtggc aagacgaagt gggatgtgct
6061 cgatggggtg gttagacggc tgttcaaaga atacatcatt catgtcgacc cagtgagtca
6121 gctagggctg aattcagaca gcgttcttgg ctacagcatt ggagaaatca agcgcagcaa
6181 cacttccgaa acaccggagc tgcttccttg tggctatctg gttggagaga acacgaccat
6241 ctcagtgact gtgaaagggc tcgcagaaaa cagcctggac tcactggtgt ttgagtcctt
6301 gattcccaag cccatcctgc agcgctacgt ctccctcctg atagagcacc gtcggatcat
6361 tctctctggc cccagcggca ctgggaaaac ctacctggcc aaccggctgt ctgagtatat
6421 agtgcttcga gagggacggg agttgacaga cggggttatc gccaccttta acgtggacca
6481 taagtccagc aaggaattgc gccagtacct gtccaacctt gctgaccagt gcaacagtga
6541 gaacaatgct gtggacatgc ccctcgtcat catcctggac aacctacacc acgtgagctc
6601 tctgggcgag atcttcaatg ggctgctcaa ctgcaagtac cacaaatgcc cttacataat
6661 tggcacaatg aaccaggcta cctcttcgac tcccaacctg cagcttcacc ataacttcag
6721 atgggtgctt tgtgccaacc acacggagcc tgtgaagggt ttccttggcc gattcctgag
6781 gaggaagctc atggaaacag agatcagtgg gcgggtgcgc aatatggagc tggtaaaaat
6841 cattgactgg attcccaagg tctggcatca cctcaaccgc ttcctggagg ctcacagttc
6901 ctcggacgtc accatcggcc cccggctctt cctgtcatgc cccatcgatg tggacggctc
6961 gagagtgtgg ttcaccgact tgtggaacta ttccattatc ccctatctcc tggaagccgt
7021 cagagaagga ctccagctct atggaaggcg cgccccctgg gaggatcctg ccaagtgggt
7081 gatggacaca tatccatggg cagccagccc acaacagcac gagtggcctc ccctgctgca
7141 gttacggcct gaggatgtcg gcttcgacgg ctactccatg cctcgggagg gatcgacaag
7201 caagcagatg ccccccagtg atgctgaagg tgacccgctg atgaacatgc tgatgaggct
7261 gcaggaggca gccaactact ccagccccca gagctatgac agcgactcca acagcaacag
7321 ccatcacgat gacatcttgg actcctcttt ggagtccact ctgtgacagg ggcccggagc
7381 ccagcgccct cctcttctcc tcaccgcatt ccacctgcat cccccacatc accctgaaga
7441 tgacttcctg agccagcccc cagccacagc cttagagctg cgggaacacc gagacccccc
7501 gtccttcagc ctcgacctgg gtgcaggcat cccgggccag ctgcctgcgg accgcttcct
7561 tccacagcga gaactgcact accttctgtt gtactttaat tattgttttg ccttgttgct
7621 gtgac
//