LOCUS AF464765 3251 bp mRNA linear HUM 12-AUG-2002
DEFINITION Homo sapiens PYRIN-containing Apaf1-like protein 3 mRNA, complete
cds.
ACCESSION AF464765
VERSION AF464765.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3251)
AUTHORS Wang,L., Manji,G.A., Grenier,J.M., Al-Garawi,A., Merriam,S.,
Lora,J.M., Geddes,B.J., Briskin,M., DiStefano,P.S. and Bertin,J.
TITLE PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates
activation of NF-kappa B and caspase-1-dependent cytokine
processing
JOURNAL J. Biol. Chem. 277 (33), 29874-29880 (2002)
PUBMED 12019269
REFERENCE 2 (bases 1 to 3251)
AUTHORS Bertin,J.
TITLE Direct Submission
JOURNAL Submitted (31-DEC-2001) Inflammation, Millennium Pharmaceuticals
Inc, 45 Sidney Street, Cambridge, MA 02139, USA
FEATURES Location/Qualifiers
source 1..3251
/db_xref="H-InvDB:HIT000080303"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 47..2989
/note="PYPAF3; PYRIN-containing nucleotide-binding
site/leucine-rich repeat family member"
/codon_start=1
/product="PYRIN-containing Apaf1-like protein 3"
/protein_id="AAL69963.1"
/translation="MTSPQLEWTLQTLLEQLNEDELKSFKSLLWAFPLEDVLQKTPWS
EVEEADGKKLAEILVNTSSENWIRNATVNILEEMNLTELCKMAKAEMMEDGQVQEIDN
PELGDAEEDSELAKPGEKEGWRNSMEKQSLVWKNTFWQGDIDNFHDDVTLRNQRFIPF
LNPRTPRKLTPYTVVLHGPAGVGKTTLAKKCMLDWTDCNLSPTLRYAFYLSCKELSRM
GPCSFAELISKDWPELQDDIPSILAQAQRILFVVDGLDELKVPPGALIQDICGDWEKK
KPVPVLLGSLLKRKMLPRAALLVTTRPRALRDLQLLAQQPIYVRVEGFLEEDRRAYFL
RHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTG
LFLRFLCSRFPQGAQLRGALRTLSLLAAQGLWAQMSVFHREDLERLGVQESDLRLFLD
GDILRQDRVSKGCYSFIHLSFQQFLTALFYALEKEEGEDRDGHAWDIGDVQKLLSGEE
RLKNPDLIQVGHFLFGLANEKRAKELEATFGCRMSPDIKQELLQCKAHLHANKPLSVT
DLKEVLGCLYESQEEELAKVVVAPFKEISIHLTNTSEVMHCSFSLKHCQDLQKLSLQV
AKGVFLENYMDFELDIEFERCTYLTIPNWARQDLRSLRLWTDFCSLFSSNSNLKFLEV
KQSFLSDSSVRILCDHVTRSTCHLQKVEIKNVTPDTAYRDFCLAFIGKKTLTHLTLAG
HIEWERTMMLMLCDLLRNHKCNLQYLRLGGHCATPEQWAEFFYVLKANQSLKHLRLSA
NVLLDEGAMLLYKTMTRPKHFLQMLSLENCRLTEASCKDLAAVLVVSKKLTHLCLAKN
PIGDTGVKFLCEGLSYPDCKLQTLVLQQCSITKLGCRYLSEALQEACSLTNLDLSINQ
IARGLWILCQALENPNCNLKHLRLKTYETNLEIKKLLEEVKEKNPKLTIDCNASGATA
PPCCDFFC"
BASE COUNT 837 a 814 c 891 g 709 t
ORIGIN
1 ggggaagttc ttcagcctta acctaaggtc tcatactcgg agcactatga catcgcccca
61 gctagagtgg actctgcaga cccttctgga gcagctgaac gaggatgaat taaagagttt
121 caaatccctt ttatgggctt ttcccctcga agacgtgcta cagaagaccc catggtctga
181 ggtggaagag gctgatggca agaaactggc agaaattctg gtcaacacct cctcagaaaa
241 ttggataagg aatgcgactg tgaacatctt ggaagagatg aatctcacgg aattgtgtaa
301 gatggcaaag gctgagatga tggaggacgg acaggtgcaa gaaatagata atcctgagct
361 gggagatgca gaagaagact cggagttagc aaagccaggt gaaaaggaag gatggagaaa
421 ttcaatggag aaacagtctt tggtctggaa gaacaccttt tggcaaggag acattgacaa
481 tttccatgac gacgtcactc tgagaaacca acggttcatt ccattcttga atcccagaac
541 acccaggaag ctaacacctt acacggtggt gctgcacggc cccgcaggcg tggggaaaac
601 cacgctggcc aaaaagtgta tgctggactg gacagactgc aacctcagcc cgacgctcag
661 atacgcgttc tacctcagct gcaaggagct cagccgcatg ggcccctgca gttttgcaga
721 gctgatctcc aaagactggc ctgaattgca ggatgacatt ccaagcatcc tagcccaagc
781 acagagaatc ctgttcgtgg tcgatggcct tgatgagctg aaagtcccac ctggggcgct
841 gatccaggac atctgcgggg actgggagaa gaagaagccg gtgcccgtcc tcctggggag
901 tttgctgaag aggaagatgt tacccagggc agccttgctg gtcaccacgc ggcccagggc
961 actgagggac ctccagctcc tggcgcagca gccgatctac gtaagggtgg agggcttcct
1021 ggaggaggac aggagggcct atttcctgag acactttgga gacgaggacc aagccatgcg
1081 tgcctttgag ctaatgagga gcaacgcggc cctgttccag ctgggctcgg cccccgcggt
1141 gtgctggatt gtgtgcacga ctctgaagct gcagatggag aagggggagg acccggtccc
1201 cacctgcctc acccgcacgg ggctgttcct gcgtttcctc tgcagccggt tcccgcaggg
1261 cgcacagctg cggggcgcgc tgcggacgct gagcctcctg gccgcgcagg gcctgtgggc
1321 gcagatgtcc gtgttccacc gagaggacct ggaaaggctc ggggtgcagg agtccgacct
1381 ccgtctgttc ctggacggag acatcctccg ccaggacaga gtctccaaag gctgctactc
1441 cttcatccac ctcagcttcc agcagtttct cactgccctg ttctacgccc tggagaagga
1501 ggagggggag gacagggacg gccacgcctg ggacatcggg gacgtacaga agctgctttc
1561 cggagaagaa agactcaaga accccgacct gattcaagta ggacacttct tattcggcct
1621 cgctaacgag aagagagcca aggagttgga ggccactttt ggctgccgga tgtcaccgga
1681 catcaaacag gaattgctgc aatgcaaagc acatcttcat gcaaataagc ccttatccgt
1741 gaccgacctg aaggaggtct tgggctgcct gtatgagtct caggaggagg agctggcgaa
1801 ggtggtggtg gccccgttca aggaaatttc tattcacctg acaaatactt ctgaagtgat
1861 gcattgttcc ttcagcctga agcattgtca agacttgcag aaactctcac tgcaggtagc
1921 aaagggggtg ttcctggaga attacatgga ttttgaactg gacattgaat ttgaaaggtg
1981 cacttaccta accattccga actgggctcg gcaggatctt cgctctcttc gcctctggac
2041 agatttctgc tctctcttca gctcaaacag caacctcaag tttctggaag tgaaacaaag
2101 cttcctgagt gactcttctg tgcggattct ttgtgaccac gtaacccgta gcacctgtca
2161 tctgcagaaa gtggagatta aaaacgtcac ccctgacacc gcgtaccggg acttctgtct
2221 tgctttcatt gggaagaaga ccctcacgca cctgaccctg gcagggcaca tcgagtggga
2281 acgcacgatg atgctgatgc tgtgtgacct gctcagaaat cataaatgca acctgcagta
2341 cctgaggttg ggaggtcact gtgccacccc ggagcagtgg gctgaattct tctatgtcct
2401 caaagccaac cagtccctga agcacctgcg tctctcagcc aatgtgctcc tggatgaggg
2461 tgccatgttg ctgtacaaga ccatgacacg cccaaaacac ttcctgcaga tgttgtcgtt
2521 ggaaaactgt cgtcttacag aagccagttg caaggacctt gctgctgtct tggttgtcag
2581 caagaagctg acacacctgt gcttggccaa gaaccccatt ggggatacag gggtgaagtt
2641 tctgtgtgag ggcttgagtt accctgattg taaactgcag accttggtgt tacagcaatg
2701 cagcataacc aagcttggct gtagatatct ctcagaggcg ctccaagaag cctgcagcct
2761 cacaaacctg gacttgagta tcaaccagat agctcgtgga ttgtggattc tctgtcaggc
2821 attagagaat ccaaactgta acctaaaaca cctacggttg aagacctatg aaactaattt
2881 ggaaatcaag aagctgttgg aggaagtgaa agaaaagaat cccaagctga ctattgattg
2941 caatgcttcc ggggcaacgg cacctccgtg ctgtgacttt ttttgctgag cagcctggga
3001 tcgctctacg aattacacag gaagcgggat tcgggtctct aagatgtctt atgaatgcag
3061 gtcagagggt cacatgttaa cactagagtc tgtcgagagg taggatttga cactggtttt
3121 ctcactattt ttgggagatt ctgcacgagt cacgcacccc cttcacatga cgctatgtac
3181 tttctcacag ggataataaa gttagagcac tctcaaaaaa aaaaaaaaaa aaaaaaaaaa
3241 aaaaaaaaaa a
//