LOCUS AF461422 2826 bp mRNA linear HUM 29-MAY-2002
DEFINITION Homo sapiens interleukin-23 receptor (IL-23R) mRNA, complete cds.
ACCESSION AF461422
VERSION AF461422.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2826)
AUTHORS Parham,C., Chirica,M., Timans,J., Vaisberg,E., Travis,M.,
Cheung,J., Pflanz,S., Zhang,R., Singh,K.P., Vega,F., To,W.,
Wagner,J., O'Farrell,A.-M., McClanahan,T., Zurawski,S., Hannum,C.,
Gorman,D., Rennick,D.M., Kastelein,R.A., de Waal Malefyt,R. and
Moore,K.W.
TITLE A receptor for the heterodimeric cytokine IL-23 is composed of
IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R
JOURNAL J. Immunol. 168 (11), 5699-5708 (2002)
PUBMED 12023369
REFERENCE 2 (bases 1 to 2826)
AUTHORS Parham,C., Chirica,M., Timans,J., Vaisberg,E., Travis,M.,
Cheung,J., Pflanz,S., Zhang,R., Singh,K.P., Vega,F., To,W.,
Wagner,J., O'Farrell,A.-M., McClanahan,T., Zurawski,S., Hannum,C.,
Gorman,D., Rennick,D.M., Kastelein,R.A., de Waal Malefyt,R. and
Moore,K.W.
TITLE Direct Submission
JOURNAL Submitted (19-DEC-2001) Immunology, DNAX Research, 901 California
Ave., Palo Alto, CA 94304, USA
FEATURES Location/Qualifiers
source 1..2826
/db_xref="H-InvDB:HIT000080220"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p31.2-1p32.1"
gene 1..2826
/gene="IL-23R"
CDS 86..1975
/gene="IL-23R"
/note="hemopoietic cytokine receptor"
/codon_start=1
/product="interleukin-23 receptor"
/protein_id="AAM44229.1"
/translation="MNQVTIQWDAVIALYILFSWCHGGITNINCSGHIWVEPATIFKM
GMNISIYCQAAIKNCQPRKLHFYKNGIKERFQITRINKTTARLWYKNFLEPHASMYCT
AECPKHFQETLICGKDISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVV
HVKSLETEEEQQYLTSSYINISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIV
IPSAAVISRAETINATVPKTIIYWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTY
VQQSEFYLEPNIKYVFQVRCQETGKRYWQPWSSPFFHKTPETVPQVTSKAFQHDTWNS
GLTVASISTGHLTSDNRGDIGLLLGMIVFAVMLSILSLIGIFNRSFRTGIKRRILLLI
PKWLYEDIPNMKNSNVVKMLQENSELMNNNSSEQVLYVDPMITEIKEIFIPEHKPTDY
KKENTGPLETRDYPQNSLFDNTTVVYIPDLNTGYKPQISNFLPEGSHLSNNNEITSLT
LKPPVDSLDSGNNPRLQKHPNFAFSVSSVNSLSNTIFLGELSLILNQGECSSPDIQNS
VEEETTMLLENDSPSETIPEQTLLPDEFVSCLGIVNEELPSINTYFPQNILESHFNRI
SLLEK"
BASE COUNT 923 a 570 c 551 g 782 t
ORIGIN
1 acaagggtgg cagcctggct ctgaagtgga attatgtgct tcaaacaggt tgaaagaggg
61 aaacagtctt ttcctgcttc cagacatgaa tcaggtcact attcaatggg atgcagtaat
121 agccctttac atactcttca gctggtgtca tggaggaatt acaaatataa actgctctgg
181 ccacatctgg gtagaaccag ccacaatttt taagatgggt atgaatatct ctatatattg
241 ccaagcagca attaagaact gccaaccaag gaaacttcat ttttataaaa atggcatcaa
301 agaaagattt caaatcacaa ggattaataa aacaacagct cggctttggt ataaaaactt
361 tctggaacca catgcttcta tgtactgcac tgctgaatgt cccaaacatt ttcaagagac
421 actgatatgt ggaaaagaca tttcttctgg atatccgcca gatattcctg atgaagtaac
481 ctgtgtcatt tatgaatatt caggcaacat gacttgcacc tggaatgctg ggaagctcac
541 ctacatagac acaaaatacg tggtacatgt gaagagttta gagacagaag aagagcaaca
601 gtatctcacc tcaagctata ttaacatctc cactgattca ttacaaggtg gcaagaagta
661 cttggtttgg gtccaagcag caaacgcact aggcatggaa gagtcaaaac aactgcaaat
721 tcacctggat gatatagtga taccttctgc agccgtcatt tccagggctg agactataaa
781 tgctacagtg cccaagacca taatttattg ggatagtcaa acaacaattg aaaaggtttc
841 ctgtgaaatg agatacaagg ctacaacaaa ccaaacttgg aatgttaaag aatttgacac
901 caattttaca tatgtgcaac agtcagaatt ctacttggag ccaaacatta agtacgtatt
961 tcaagtgaga tgtcaagaaa caggcaaaag gtactggcag ccttggagtt caccgttttt
1021 tcataaaaca cctgaaacag ttccccaggt cacatcaaaa gcattccaac atgacacatg
1081 gaattctggg ctaacagttg cttccatctc tacagggcac cttacttctg acaacagagg
1141 agacattgga cttttattgg gaatgatcgt ctttgctgtt atgttgtcaa ttctttcttt
1201 gattgggata tttaacagat cattccgaac tgggattaaa agaaggatct tattgttaat
1261 accaaagtgg ctttatgaag atattcctaa tatgaaaaac agcaatgttg tgaaaatgct
1321 acaggaaaat agtgaactta tgaataataa ttccagtgag caggtcctat atgttgatcc
1381 catgattaca gagataaaag aaatcttcat cccagaacac aagcctacag actacaagaa
1441 ggagaataca ggacccctgg agacaagaga ctacccgcaa aactcgctat tcgacaatac
1501 tacagttgta tatattcctg atctcaacac tggatataaa ccccaaattt caaattttct
1561 gcctgaggga agccatctca gcaataataa tgaaattact tccttaacac ttaaaccacc
1621 agttgattcc ttagactcag gaaataatcc caggttacaa aagcatccta attttgcttt
1681 ttctgtttca agtgtgaatt cactaagcaa cacaatattt cttggagaat taagcctcat
1741 attaaatcaa ggagaatgca gttctcctga catacaaaac tcagtagagg aggaaaccac
1801 catgcttttg gaaaatgatt cacccagtga aactattcca gaacagaccc tgcttcctga
1861 tgaatttgtc tcctgtttgg ggatcgtgaa tgaggagttg ccatctatta atacttattt
1921 tccacaaaat attttggaaa gccacttcaa taggatttca ctcttggaaa agtagagctg
1981 tgtggtcaaa atcaatatga gaaagctgcc ttgcaatctg aacttgggtt ttccctgcaa
2041 tagaaattga attctgcctc tttttgaaaa aaatgtattc acatacaaat cttcacatgg
2101 acacatgttt tcatttccct tggataaata cctaggtagg ggattgctgg gccatatgat
2161 aagcatatgt ttcagttcta ccaatcttgt ttccagagta gtgacatttc tgtgctccta
2221 ccatcaccat gtaagaattc ccgggagctc catgcctttt taattttagc cattcttctg
2281 cctcatttct taaaattaga gaattaaggt cccgaaggtg gaacatgctt catggtcaca
2341 catacaggca caaaaacagc attatgtgga cgcctcatgt attttttata gagtcaacta
2401 tttcctcttt attttccctc attgaaagat gcaaaacagc tctctattgt gtacagaaag
2461 ggtaaataat gcaaaatacc tggtagtaaa ataaatgctg aaaattttcc tttaaaatag
2521 aatcattagg ccaggcgtgg tggctcatgc ttgtaatccc agcactttgg taggctgagg
2581 tgggtggatc acctgaggtc aggagttcga gtccagcctg gccaatatgc tgaaaccctg
2641 tctctactaa aattacaaaa attagccggc catggtggca ggtgcttgta atcccagcta
2701 cttgggaggc tgaggcagga gaatcacttg aaccaggaag gcagaggttg cactgagctg
2761 agattgtgcc actgcactcc agcctgggca acaagagcaa aactctgtct ggaaaaaaaa
2821 aaaaaa
//