LOCUS AF442151 2853 bp mRNA linear HUM 21-DEC-2001
DEFINITION Homo sapiens viperin mRNA, complete cds.
ACCESSION AF442151
VERSION AF442151.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2853)
AUTHORS Chin,K.C. and Cresswell,P.
TITLE Inaugural Article: Viperin (cig5), an IFN-inducible antiviral
protein directly induced by human cytomegalovirus
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 98 (26), 15125-15130 (2001)
PUBMED 11752458
REFERENCE 2 (bases 1 to 2853)
AUTHORS Chin,K.C. and Cresswell,P.
TITLE Direct Submission
JOURNAL Submitted (31-OCT-2001) Immunobiology, Yale University, 310 Cedar
St., New Haven, CT 06511, USA
FEATURES Location/Qualifiers
source 1..2853
/db_xref="H-InvDB:HIT000079730"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 25..1110
/note="CIG5; virus inhibitory protein; endoplasmic
reticulum-associated, interferon induced; inhibits human
cytomegalovirus replication"
/codon_start=1
/product="viperin"
/protein_id="AAL50053.1"
/translation="MWVLTPAAFAGKLLSVFRQPLSSLWRSLVPLFCWLRATFWLLAT
KRRKQQLVLRGPDETKEEEEDPPLPTTPTSVNYHFTRQCNYKCGFCFHTAKTSFVLPL
EEAKRGLLLLKEAGMEKINFSGGEPFLQDRGEYLGKLVRFCKVELRLPSVSIVSNGSL
IRERWFQNYGEYLDILAISCDSFDEEVNVLIGRGQGKKNHVENLQKLRRWCRDYRVAF
KINSVINRFNVEEDMTEQIKALNPVRWKVFQCLLIEGENCGEDALREAERFVIGDEEF
ERFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCRKGRKDPSKSILDVGVEEAIK
FSGFDEKMFLKRGGKYIWSKADLKLDW"
BASE COUNT 854 a 537 c 653 g 809 t
ORIGIN
1 gctctgctcc aggcatctgc cacaatgtgg gtgcttacac ctgctgcttt tgctgggaag
61 ctcttgagtg tgttcaggca acctctgagc tctctgtgga ggagcctggt cccgctgttc
121 tgctggctga gggcaacctt ctggctgcta gctaccaaga ggagaaagca gcagctggtc
181 ctgagagggc cagatgagac caaagaggag gaagaggacc ctcctctgcc caccacccca
241 accagcgtca actatcactt cactcgccag tgcaactaca aatgcggctt ctgtttccac
301 acagccaaaa catcctttgt gctgcccctt gaggaagcaa agagaggatt gcttttgctt
361 aaggaagctg gtatggagaa gatcaacttt tcaggtggag agccatttct tcaagaccgg
421 ggagaatacc tgggcaagtt ggtgaggttc tgcaaagtag agttgcggct gcccagcgtg
481 agcatcgtga gcaatggaag cctgatccgg gagaggtggt tccagaatta tggtgagtat
541 ttggacattc tcgctatctc ctgtgacagc tttgacgagg aagtcaatgt ccttattggc
601 cgtggccaag gaaagaagaa ccatgtggaa aaccttcaaa agctgaggag gtggtgtagg
661 gattatagag tcgctttcaa gataaattct gtcattaatc gtttcaacgt ggaagaggac
721 atgacggaac agatcaaagc actaaaccct gtccgctgga aagtgttcca gtgcctctta
781 attgagggtg agaattgtgg agaagatgct ctaagagaag cagaaagatt tgttattggt
841 gatgaagaat ttgaaagatt cttggagcgc cacaaagaag tgtcctgctt ggtgcctgaa
901 tctaaccaga agatgaaaga ctcctacctt attctggatg aatatatgcg ctttctgaac
961 tgtagaaagg gacggaagga cccttccaag tccatcctgg atgttggtgt agaagaagct
1021 ataaaattca gtggatttga tgaaaagatg tttctgaagc gaggaggaaa atacatatgg
1081 agtaaggctg atctgaagct ggattggtag agcggaaagt ggaacgagac ttcaacacac
1141 cagtgggaaa actcctagag taactgccat tgtctgcaat actatcccgt tggtatttcc
1201 cagtggctga aaacctgatt ttctgctgca cgtggcatct gattacctgt ggtcactgaa
1261 cacacgaata acttggatag caaatcctga gacaatggaa aaccattaac tttacttcat
1321 tggcttataa ccttgttgtt attgaaacag cacttctgtt tttgagtttg ttttagctaa
1381 aaagaaggaa tacacacagg aataatgacc ccaaaaatgc ttagataagg cccctataca
1441 caggacctga catttagctc aatgatgcgt ttgtaagaaa taagctctag tgatatctgt
1501 gggggcaaaa tttaatttgg atttgatttt ttaaaacaat gtttactgcg atttctatat
1561 ttccattttg aaactatttc ttgttccagg tttgttcatt tgacagagtc agtatttttt
1621 gccaaatatc cagataacca gttttcacat ctgagacatt acaaagtatc tgcctcaatt
1681 atttctgctg gttataatgc tttttttttt ttgcctttat gccattgcag tcttgtactt
1741 tttactgtga tgtacagaaa tagtcaacag atgtttccaa gaacatatga tatgataatc
1801 ctaccaattt tcaagaagtc tctagaaaga gataacacat ggaaagacgg cgtggtgcag
1861 cccagcccac ggtgcctgtt ccatgaatgc tggctaccta tgtgtgtggt acctgttgtg
1921 tccctttctc ttcaaagatc cctgagcaaa acaaagatac gctttccatt tgatgatgga
1981 gttgacatgg aggcagtgct tgcattgctt tgttcgccta tcatctggcc acatgaggct
2041 gtcaagcaaa agaataggag tgtagttgag tagctggttg gccctacatt tctgagaagt
2101 gacgttacac tgggttggca taagatatcc taaaatcacg ctggaacctt gggcaaggaa
2161 gaatgtgagc aagagtagag agagtgcctg gatttcatgt cagtgaagcc atgtcaccat
2221 atcatatttt tgaatgaact ctgagtcagt tgaaataggg taccatctag gtcagtttaa
2281 gaagagtcag ctcagagaaa gcaagcataa gggaaaatgt cacgtaaact agatcaggga
2341 acaaaatcct ctccttgtgg aaatatccca tgcagtttgt tgatacaact tagtatctta
2401 ttgcctaaaa aaaaatttct tatcattgtt tcaaaaaagc aaaatcatgg aaaatttttg
2461 ttgtccaggc aaataaaagg tcattttaat ttaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2521 aaaaggccaa ggaaaaaaaa tattcctact taaattttaa gtctataatt caatttaaat
2581 atgtgtgtgt ctcatccagg ataggatagg ttgtcttcta ttttccattt tacctattta
2641 ctttttttgt aagaaaagag aagaatgaat tctaaagatg ttccccatgg gttttgattg
2701 tgtctaagct atgatgacct tcatataatc agcataaaca taaaacaaat tttttactta
2761 acatgagtgc actttactaa tcctcatggc acagtggctc acgcctgtaa tcccagcact
2821 tggggaggac aatgtggggt ggatcacgag gtc
//