LOCUS AF430017 3803 bp mRNA linear HUM 26-JUL-2016
DEFINITION Homo sapiens intestinal membrane mucin MUC17 (MUC17) mRNA, partial
cds.
ACCESSION AF430017
VERSION AF430017.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3803)
AUTHORS Gum,J.R. Jr., Crawley,S.C., Hicks,J.W., Szymkowski,D.E. and
Kim,Y.S.
TITLE MUC17, a novel membrane-tethered mucin
JOURNAL Biochem. Biophys. Res. Commun. 291 (3), 466-475 (2002)
PUBMED 11855812
REFERENCE 2 (bases 1 to 3803)
AUTHORS Gum,J.R. Jr.
TITLE Direct Submission
JOURNAL Submitted (08-OCT-2001) GI Research, VAMC-SF, 4150 Clement Street,
San Francisco, CA 94121, USA
FEATURES Location/Qualifiers
source 1..3803
/db_xref="H-InvDB:HIT000079529"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="7"
/map="7q22"
gene <1..3803
/gene="MUC17"
CDS <1..3092
/gene="MUC17"
/note="expressed in large and small intestine; also
expressed in pancreatic and colon cancer cells"
/codon_start=3
/product="intestinal membrane mucin MUC17"
/protein_id="AAL89737.1"
/translation="LSTTPVASSEASTLSTSPVDTSTPVTNSSPTNSSPTTAEVTSMP
TSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTM
RMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVIT
LPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGT
TMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDS
TTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTL
EGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFS
IPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTAS
TPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELN
TPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSA
TSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEA
VTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPRTTTCFGDGCQNTASR
CKNGGTWDGLKCQCPNLYYGELCEEVVSSIDIGPPETISAQMELTVTVTSVKFTEELK
NHSSQEFQEFKQTFTEQMNIVYSGIPEYVGVNITKLRLGSVVVEHDVLLRTKYTPEYK
TVLDNATEVVKEKITKVTTQQIMINDICSDMMCFNTTGTQVQNITVTQYDPEEDCRKM
AKEYGDYFVVEYRDQKPYCISPCEPGFSVSKNCNLGKCQMSLSGPQCLCVTTETHWYS
GETCNQGTQKSLVYGLVGAGVVLMLIILVALLMLVFRSKREVKRQKYRLSQLYKWQEE
DSGPAPGTFQNIGFDICQDDDSIHLESIYSNFQPSLRHIDPETKIRIQRPQVMTTSF"
misc_feature 2001..2120
/gene="MUC17"
/note="Region: EGF-like domain"
misc_feature 2154..2471
/gene="MUC17"
/note="Region: SEA module"
misc_feature 2631..2759
/gene="MUC17"
/note="Region: EGF-like domain"
misc_feature 2778..2849
/gene="MUC17"
/note="Region: transmembrane domain"
misc_feature 2850..3089
/gene="MUC17"
/note="Region: cytoplasmic domain"
repeat_region 1..887
/gene="MUC17"
/rpt_type=dispersed
BASE COUNT 1029 a 1128 c 750 g 895 t
ORIGIN
1 ctctcagtac cacgccggtg gccagttctg aggctagcac cctttcaaca agtcctgttg
61 acaccagcac acctgtgacc aattcttctc caaccaattc atctcctaca actgctgaag
121 ttaccagcat gccaacatca actgctggtg aaggaagcac tccattaaca aatatgcctg
181 tcagcaccac accggtggcc agttctgagg ctagcaccct ttcaacaact cctgttgact
241 ccaacacttt tgttaccagt tctagtcaag ccagttcatc tccagcaact cttcaggtca
301 ccactatgcg tatgtctact ccaagtgaag gaagctcttc attaacaact atgctcctca
361 gcagcacata tgtgaccagt tctgaggcta gcacaccttc cactccttct gttgacagaa
421 gcacacctgt gaccacttct actcagagca attctactcc tacacctcct gaagttatca
481 ccctgccaat gtcaactcct agtgaagtaa gcactccatt aaccattatg cctgtcagca
541 ccacatcggt gaccatttct gaggctggca cagcttcaac acttcctgtt gacaccagca
601 cacctgtgat cacttctacc caagtcagtt catctcctgt gactcctgaa ggtaccacca
661 tgccaatctg gacgcctagt gaaggaagca ctccattaac aactatgcct gtcagcacca
721 cacgtgtgac cagctctgag ggtagcaccc tttcaacacc ttctgttgtc accagcacac
781 ctgtgaccac ttctactgaa gccatttcat cttctgcaac tcttgacagc accaccatgt
841 ctgtgtcaat gcccatggaa ataagcaccc ttgggaccac tattcttgtc agtaccacac
901 ctgttacgag gtttcctgag agtagcaccc cttccatacc atctgtttac accagcatgt
961 ctatgaccac tgcctctgaa ggcagttcat ctcctacaac tcttgaaggc accaccacca
1021 tgcctatgtc aactacgagt gaaagaagca ctttattgac aactgtcctc atcagcccta
1081 tatctgtgat gagtccttct gaggccagca cactttcaac acctcctggt gataccagca
1141 cacctttgct cacctctacc aaagccggtt cattctccat acctgctgaa gtcactacca
1201 tacgtatttc aattaccagt gaaagaagca ctccattaac aactctcctt gtcagcacca
1261 cacttccaac tagctttcct ggggccagca tagcttcgac acctcctctt gacacaagca
1321 caacttttac cccttctact gacactgcct caactcccac aattcctgta gccaccacca
1381 tatctgtatc agtgatcaca gaaggaagca cacctgggac aaccattttt attcccagca
1441 ctcctgtcac cagttctact gctgatgtct ttcctgcaac aactggtgct gtatctaccc
1501 ctgtgataac ttccactgaa ctaaacacac catcaacctc cagtagtagt accaccacat
1561 ctttttcaac tactaaggaa tttacaacac ccgcaatgac tactgcagct cccctcacat
1621 atgtgaccat gtctactgcc cccagcacac ccagaacaac cagcagaggc tgcactactt
1681 ctgcatcaac gctttctgca accagtacac ctcacacctc tacttctgtc accacccgtc
1741 ctgtgacccc ttcatcagaa tccagcaggc cgtcaacaat tacttctcac accatcccac
1801 ctacatttcc tcctgctcac tccagtacac ctccaacaac ctctgcctcc tccacgactg
1861 tgaaccctga ggctgtcacc accatgacca ccaggacaaa acccagcaca cggaccactt
1921 ccttccccac ggtgaccacc accgctgtcc ccacgaatac tacaattaag agcaacccca
1981 cctcaactcc tactgtgcca agaaccacaa catgctttgg agatgggtgc cagaatacgg
2041 cctctcgctg caagaatgga ggcacctggg atgggctcaa gtgccagtgt cccaacctct
2101 attatgggga gttgtgtgag gaggtggtca gcagcattga catagggcca ccggagacta
2161 tctctgccca aatggaactg actgtgacag tgaccagtgt gaagttcacc gaagagctaa
2221 aaaaccactc ttcccaggaa ttccaggagt tcaaacagac attcacggaa cagatgaata
2281 ttgtgtattc cgggatccct gagtatgtcg gggtgaacat cacaaagcta cgtcttggca
2341 gtgtggtggt ggagcatgac gtcctcctaa gaaccaagta cacaccagaa tacaagacag
2401 tattggacaa tgccacygaa gtagtgaaag agaaaatcac aaaagtgacc acacagcaaa
2461 taatgattaa tgatatttgc tcagacatga tgtgtttcaa caccactggc acccaagtgc
2521 aaaacattac ggtgacccag tacgaccctg aagaggactg ccggaagatg gccaaggaat
2581 atggagacta cttcgtagtg gagtaccggg accagaagcc atactgcatc agcccctgtg
2641 agcctggctt cagtgtctcc aagaactgta acctcggcaa gtgccagatg tctctaagtg
2701 gacctcagtg cctctgcgtg accacggaaa ctcactggta cagtggggag acctgtaacc
2761 agggcaccca gaagagtctg gtgtacggcc tcgtgggggc aggggtcgtg ctgatgctga
2821 tcatcctggt agctctcctg atgctcgttt tccgctccaa gagagaggtg aaacggcaaa
2881 agtacagatt gtctcagtta tacaagtggc aagaagagga cagtggacca gctcctggga
2941 ccttccaaaa cattggcttt gacatctgcc aagatgatga ttccatccac ctggagtcca
3001 tctatagtaa tttccagccc tccttgagac acatagaccc tgaaacaaag atccgaattc
3061 agaggcctca ggtaatgacg acatcatttt aaggcatgga gctgagaagt ctgggagtga
3121 ggagatccca gtccggctaa gcttggtgga gcattttccc attgagagcc ttccatggga
3181 actcaatgtt cccattgtaa gtacaggaaa caagccccgt acttaccaag gagaaagagg
3241 agagacagca gtgctgggag attctcaaat agaaacccgt ggacgctcca atgggcttgt
3301 catgatatca ggctaggctt tcctgctcat ttttcaaaga cgctccagat ttgagggtac
3361 tctgactgta acatctatca ccccattgat cgccaggatt gatttggttg atctggctga
3421 gcaggcgggt gtccccgtcc tccctcactg ccccatatgt gtccctccta aagctgcatg
3481 ctcagttgaa gaggacgaga ggacgacctt ctctgataga ggaggaccac gcttcagtca
3541 aaggcataca agtatctatc tggacttccc tgctggcact tccaaacaag ctcagagatg
3601 ttcctcccct catctgcccg ggttcagtac catggacagc gccctcgacc cgctgtttac
3661 aaccatgacc ccttggacac tggactgcat gcactttaca tatcacaaaa tgctctcata
3721 agaattattg cataccatct tcatgaaaaa cacctgtatt taaatatagg gcatttacct
3781 tttggtaaag aaaaaaaaaa aaa
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