LOCUS AF428263 3410 bp mRNA linear HUM 11-JAN-2002
DEFINITION Homo sapiens endothelin converting enzyme-2A (ECE2) mRNA, complete
cds; alternatively spliced.
ACCESSION AF428263
VERSION AF428263.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3410)
AUTHORS Lorenzo,M.N., Khan,R.Y., Wang,Y., Tai,S.C., Chan,G.C., Cheung,A.H.
and Marsden,P.A.
TITLE Human endothelin converting enzyme-2 (ECE2): characterization of
mRNA species and chromosomal localization
JOURNAL Biochim. Biophys. Acta 1522 (1), 46-52 (2001)
PUBMED 11718899
REFERENCE 2 (bases 1 to 3410)
AUTHORS Lorenzo,M.-N., Khan,R.Y., Wang,Y., Tai,S.C., Chan,G.C., Cheung,A.H.
and Marsden,P.A.
TITLE Direct Submission
JOURNAL Submitted (05-OCT-2001) Medicine, University of Toronto, 1 King's
College Circle Rm. 7358, Toronto, Ontario M5S1A8, Canada
FEATURES Location/Qualifiers
source 1..3410
/db_xref="H-InvDB:HIT000079522"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..3410
/gene="ECE2"
CDS 255..2618
/gene="ECE2"
/note="ECE-2A; alternatively spliced isoform ECE-2B
deposited in GenBank Accession Number AF192531"
/codon_start=1
/product="endothelin converting enzyme-2A"
/protein_id="AAL30386.1"
/translation="MQARHAHVPQLRWETMDVRKLDFPSASFDVVLEKGTLDALLAGE
RDPWTVSSEGVHTVDQVLSEVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVA
LGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGR
SRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLR
DLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQS
GLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANI
TVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYL
QQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQ
TCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQ
AAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQL
RKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGH
ELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTL
GENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESS
HEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW"
BASE COUNT 727 a 968 c 993 g 722 t
ORIGIN
1 agttaccgga gcggaactgc gggtaccgcg aagtcgagta ctgggatcag cgctaccaag
61 gcgcagccga ttctgccccc tacgattggt tcggggactt ctcctccttc cgtgccctcc
121 tagagccgga gctgcggccc gaggaccgta tccttgtgct aggttgcggg aacagtgccc
181 tgagctacga gctgttcctc ggaggcttcc ctaatgtgac cagtgtggac tactcatcag
241 tcgtggtggc tgccatgcag gctcgccatg cccatgtgcc gcagctgcgc tgggagacca
301 tggatgtgcg gaagctggac ttccccagtg cttcttttga tgtggtgctc gagaagggca
361 cgctggatgc cctgctggct ggggaacgag atccctggac cgtgtcctct gaaggtgtcc
421 acactgtgga ccaggtgttg agtgaggtgg gattccagaa ggggacaaga cagctgttag
481 gctcacgcac gcagctggag ctggtcttag caggtgcctc tctactgctg gctgcactgc
541 ttctgggctg ccttgtggcc ctaggggtcc agtaccacag agacccatcc cacagcacct
601 gccttacaga ggcctgcatt cgagtggctg gaaaaatcct ggagtccctg gaccgagggg
661 tgagcccctg tgaggacttt taccagttct cctgtggggg ctggattcgg aggaaccccc
721 tgcccgatgg gcgttctcgc tggaacacct tcaacagcct ctgggaccaa aaccaggcca
781 tactgaagca cctgcttgaa aacaccacct tcaactccag cagtgaagct gagcagaaga
841 cacagcgctt ctacctatct tgcctacagg tggagcgcat tgaggagctg ggagcccagc
901 cactgagaga cctcattgag aagattggtg gttggaacat tacggggccc tgggaccagg
961 acaactttat ggaggtgttg aaggcagtag cagggaccta cagggccacc ccattcttca
1021 ccgtctacat cagtgctgac tctaagagtt ccaacagcaa tgttatccag gtggaccagt
1081 ctgggctctt tctgccctct cgggattact acttaaacag aactgccaat gagaaagtgc
1141 tcactgccta tctggattac atggaggaac tggggatgct gctgggtggg cggcccacct
1201 ccacgaggga gcagatgcag caggtgctgg agttggagat acagctggcc aacatcacag
1261 tgccccagga ccagcggcgc gacgaggaga agatctacca caagatgagc atttcggagc
1321 tgcaggctct ggcgccctcc atggactggc ttgagttcct gtctttcttg ctgtcaccat
1381 tggagttgag tgactctgag cctgtggtgg tgtatgggat ggattatttg cagcaggtgt
1441 cagagctcat caaccgcacg gaaccaagca tcctgaacaa ttacctgatc tggaacctgg
1501 tgcaaaagac aacctcaagc ctggaccgac gctttgagtc tgcacaagag aagctgctgg
1561 agaccctcta tggcactaag aagtcctgtg tgccgaggtg gcagacctgc atctccaaca
1621 cggatgacgc ccttggcttt gctttggggt ccctcttcgt gaaggccacg tttgaccggc
1681 aaagcaaaga aattgcagag gggatgatca gcgaaatccg gaccgcattt gaggaggccc
1741 tgggacagct ggtttggatg gatgagaaga cccgccaggc agccaaggag aaagcagatg
1801 ccatctatga tatgattggt ttcccagact ttatcctgga gcccaaagag ctggatgatg
1861 tttatgacgg gtacgaaatt tctgaagatt ctttcttcca aaacatgttg aatttgtaca
1921 acttctctgc caaggttatg gctgaccagc tccgcaagcc tcccagccga gaccagtgga
1981 gcatgacccc ccagacagtg aatgcctact accttccaac taagaatgag atcgtcttcc
2041 ccgctggcat cctgcaggcc cccttctatg cccgcaacca ccccaaggcc ctgaacttcg
2101 gtggcatcgg tgtggtcatg ggccatgagt tgacgcatgc ctttgatgac caagggcgcg
2161 agtatgacaa agaagggaac ctgcggccct ggtggcagaa tgagtccctg gcagccttcc
2221 ggaaccacac ggcctgcatg gaggaacagt acaatcaata ccaggtcaat ggggagaggc
2281 tcaacggccg ccagacgctg ggggagaaca ttgctgacaa cggggggctg aaggctgcct
2341 acaatgctta caaagcatgg ctgagaaagc atggggagga gcagcaactg ccagccgtgg
2401 ggctcaccaa ccaccagctc ttcttcgtgg gatttgccca ggtgtggtgc tcggtccgca
2461 caccagagag ctctcacgag gggctggtga ccgaccccca cagccctgcc cgcttccgcg
2521 tgctgggcac tctctccaac tcccgtgact tcctgcggca cttcggctgc cctgtcggct
2581 cccccatgaa cccagggcag ctgtgtgagg tgtggtagac ctggatcagg ggagaaatgc
2641 ccagctgtca ccagacctgg ggcagctctc ctgacaaagc tgtttgctct tgggttggga
2701 ggaagcaaat gcaagctggg ctgggtctag tccctccccc ccacaggtga catgagtaca
2761 gaccctcctc aatcaccaca ttgtgcctct gctttggggg tgcccctgcc tccagcagag
2821 cccccaccat tcactgtgac atctttccgt gtcaccctgc ctggaagagg tctgggtggg
2881 gaggccagtt cccataggaa ggagtctgcc tcttctgtcc ccaggctcac tcagcctggc
2941 ggccatgggg cctgccgtgc ctgccccact gtgacccaca ggcctgggtg gtgtacctcc
3001 tggacttctc cccaggctca ctcagtgcgc acttaggggt ggactcagct ctgtctggct
3061 caccctcacg ggctaccccc acctcaccct gtgctccttg tgccactgct cccagtgctg
3121 ctgctgacct tcactgacag ctcctagtgg aagcccaagg gcctctgaaa gcctcctgct
3181 gcccactgtt tccctgggct gagaggggaa gtgcatatgt gtagcgggta ctggttcctg
3241 tgtcttaggg cacaagcctt agcaaatgat tgattctccc tggacaaagc aggaaagcag
3301 atagagcagg gaaaaggaag aacagagttt atttttacag aaaagagggt gggagggtgt
3361 ggtcttggcc cttataggac cctgtgccaa taaacagaca tgcatccgtc
//