LOCUS AF427340 3071 bp mRNA linear HUM 31-AUG-2005
DEFINITION Homo sapiens putative DEAD/DEXH helicase DDX32 mRNA, complete cds,
alternatively spliced.
ACCESSION AF427340
VERSION AF427340.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3071)
AUTHORS Abdelhaleem,M.
TITLE The novel helicase homologue DDX32 is down-regulated in acute
lymphoblastic leukemia
JOURNAL Leuk. Res. 26 (10), 945-954 (2002)
PUBMED 12163057
REFERENCE 2 (bases 1 to 3071)
AUTHORS Abdelhaleem,M.M.
TITLE Direct Submission
JOURNAL Submitted (03-OCT-2001) Hematopathology, Pediatric Laboratory
Medicine, Hospital for Sick Children, 555 University Avenue,
Toronto, Ontario M5G 1X8, Canada
FEATURES Location/Qualifiers
source 1..3071
/db_xref="H-InvDB:HIT000079491"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
/map="10q26"
CDS 493..2724
/note="alternatively spliced"
/codon_start=1
/product="putative DEAD/DEXH helicase DDX32"
/protein_id="AAL26550.1"
/translation="MEEEGLECPNSSSEKRYFPESLDSSDGDEEEVLACEDLELNPFD
GLPYSSRYYKLLKEREDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEY
CLSIHYQHGGVICTQVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTNETILRY
CTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSS
PHLISKLNSYYGNVPVIEVKNKHPVEVVYLSEAQKDSFESILRLIFEIHHSGEKGDIV
VFLACEQDIEKVCETVYQGSNLNPDLGELVVVPLYPKEKCSLFKPLDETEKRCQVYQR
RVVLTTSSGEFLIWSNSVRFVIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQIL
GSSSSGKFFCLYTEEFASKDMTPLKPAEMQEANLTSMVLFMKRIDIAGLGHCDFMNRP
APESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLT
IAAMVTAPNCFSHVPHGAEEAALTCWKTFLHPEGDHFTLISIYKAYQDTTLNSSSEYC
VEKWCRDYFLNCSALRMADVIRAELLEIIKRIELPYAEPAFGSKENTLNIKKALLSGY
FMQIARDVDGSGNYLMLTHKQVAQLHPLSGYSITKKMPEWVLFHKFSISENNYIRITS
EISPELFMQLVPQYYFSNLPPSESKDILQQVVDHLSPVSTMNKEQQMCETCPETEQRC
TLQ"
misc_feature 493..2721
/note="Region: Preny group binding site; CAAX box"
misc_feature 928..1701
/note="Region: DEAD/DEXH domain"
BASE COUNT 923 a 616 c 670 g 862 t
ORIGIN
1 gaggcagaga gcacgaggcc cagtgcagaa tcattttctg aaccagccag gaaataccgg
61 aacccaccaa actttaaaca ccagcctaaa ttattcctgt tcttttaagc aggcagcaga
121 aatgacagaa acccgttaac agaaaaaaaa aaaataatgc ttttcatttg aactcctgtg
181 cattttcttt ttaacttata tgtgttccta attttcctta ctctttttgt ttgtttgttt
241 cttagtgtgg tttattgaca atcatttaca atgccgaaga gtgctgtagt gagccagcac
301 agtgggtaac acagcaacgg agaacagatg caggtttgag gaatttaact tgctaaaacc
361 ttgaactgaa gtcttagaga ttggaacata cgggtttgta taaataggct tttaagccct
421 gtttgcaatg ggttactgat aggagaaact tgcttgtgga atgtcagctg cgtgagctca
481 ctgtcagaca agatggaaga agaagggctg gagtgtccaa actcttcctc tgaaaaacgc
541 tattttcctg aatccctgga ttccagcgat ggggatgagg aagaggtttt ggcctgtgag
601 gatttggaac ttaacccctt tgatggattg ccatattcat cacgttatta taaacttctg
661 aaagaaagag aagatcttcc tatatggaaa gaaaaatact cctttatgga gaacctgctt
721 caaaatcaaa tcgtgattgt ttcaggagat gctaaatgtg gtaagagcgc tcaggttcct
781 cagtggtgtg ctgaatattg tctttccatc cactaccagc acgggggcgt gatatgcaca
841 caggtccaca agcagactgt ggtccagctc gccctgcggg tggcggatga aatggatgtt
901 aacattggtc atgaggttgg ctacgtgatc cctttcgaga actgctgtac caacgaaaca
961 atcctgaggt attgtactga tgatatgctg caaagagaaa tgatgtccaa tccttttttg
1021 ggtagctatg gggtcatcat cttagatgat attcatgaaa gaagcattgc aactgatgtg
1081 ttacttggac ttcttaaaga tgttttacta gcaagaccag aactgaagct cataattaac
1141 tcctcacctc acctgatcag caaactcaat tcttattatg gaaacgtgcc tgtcatagaa
1201 gtgaaaaata aacaccctgt ggaggttgtg taccttagtg aggctcaaaa ggattctttt
1261 gagtctattt tacgccttat ctttgaaatt caccactcgg gtgagaaagg tgacattgta
1321 gtctttctgg cctgtgaaca agatattgag aaagtctgtg aaactgtcta tcaaggatct
1381 aacctaaacc cagatcttgg agaactggtg gttgttcctt tgtatccaaa agagaaatgt
1441 tcattgttca agccactcga tgaaacagaa aaaagatgcc aagtttatca aagaagagtg
1501 gtgttaacta ctagctctgg agagtttttg atctggagca actcagtcag atttgttatc
1561 gatgtgggtg tggaaagaag aaaggtgtac aacccgagaa taagagcaaa ctcgctcgtc
1621 atgcagccca tcagccagag ccaggcagag atacgcaagc agattcttgg ctcatcttct
1681 tcaggaaaat ttttctgcct gtacactgaa gaatttgcct ccaaagacat gacgccactg
1741 aagccagcag aaatgcagga agccaaccta acaagcatgg tgctttttat gaagaggata
1801 gacattgcgg gcctaggcca ctgtgacttc atgaacagac cagcaccaga aagtttgatg
1861 caggcattgg aagacttaga ttatctggca gcactggata atgatggaaa tctttctgaa
1921 tttggaatca tcatgtcaga gtttcctctt gatccacaac tctcgaagtc tatcttagcg
1981 tcctgtgaat ttgactgtgt agatgaagtg ctaacaatcg cagccatggt aacagctcca
2041 aattgctttt cacatgtgcc acatggagct gaagaggctg ccttgacttg ttggaagaca
2101 tttttacatc ccgaaggaga tcactttacc ctcatcagca tttacaaggc ttaccaagac
2161 acaactctga attctagcag tgagtactgt gtggaaaagt ggtgtcgtga ttacttcctc
2221 aactgttcag cactcagaat ggcagatgtt attcgagctg aactcttaga aattatcaag
2281 cgaatcgagc ttccctatgc agaacctgct tttggctcca aggaaaacac tctaaacata
2341 aagaaagctc ttctgtccgg ttactttatg cagattgctc gggatgttga tggatcaggt
2401 aactacttaa tgctgacaca taagcaggtt gctcagctgc atcccctgtc tggttactca
2461 atcaccaaga agatgccaga gtgggtcctc ttccataaat tcagcatttc tgagaacaac
2521 tacatcagga ttacctcaga aatctctcct gaactattta tgcagctggt accacaatac
2581 tatttcagta atctgcctcc tagtgaaagt aaggacattc tacagcaagt agtggatcac
2641 ctatcccctg tgtcaacaat gaataaggaa cagcaaatgt gtgagacgtg ccctgaaact
2701 gaacagagat gcactctcca gtgactcccc agcaaacaca aggtgcagca gggtcccaaa
2761 ggtagctgga tggctgaact gctggatatg ggagatacat gacgcgaaga cggatttcac
2821 atccacagga cggtcttgaa gaaaataaca ctgtgtatat tattttaaaa taaaaaatag
2881 aagtttttat tgagttcttt aaattactac tccatgcttt tcttcttctt ggaaaagttt
2941 ttaaatcaac cactcataat ttgaccaaaa ttttaaaaaa ctggtatttt gtaaatgtgt
3001 cagagacaca tgggacagaa ccctactttt tgtagaggaa cttaatctga ataaagtctg
3061 agtttttcag t
//