LOCUS AF425231 9646 bp mRNA linear HUM 28-MAR-2002
DEFINITION Homo sapiens chromodomain helicase DNA binding protein 5 (CHD5)
mRNA, complete cds.
ACCESSION AF425231
VERSION AF425231.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 9646)
AUTHORS Thompson,P.M., Gotoh,T., White,P.S. and Brodeur,G.M.
TITLE CHD5, a New Member of the Chromodomain Gene Family, is
Preferentially Expressed in the Nervous System
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 9646)
AUTHORS Thompson,P.M., Gotoh,T., White,P.S. and Brodeur,G.M.
TITLE Direct Submission
JOURNAL Submitted (27-SEP-2001) Oncology, Children's Hospital of
Philadelphia, 3615 Civic Center Blvd., Philadelphia, PA 19104-4318,
USA
FEATURES Location/Qualifiers
source 1..9646
/db_xref="H-InvDB:HIT000079429"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p36.3"
gene 1..9646
/gene="CHD5"
CDS 101..5965
/gene="CHD5"
/codon_start=1
/product="chromodomain helicase DNA binding protein 5"
/protein_id="AAL98962.1"
/translation="MRGPVGTEEELPRLFAEEMENEDEMSEEEDGGLEAFDDFFPVEP
VSLPKKKKPKKLKENKCKGKRKKKEGSNDELSENEEDLEEKSESEGSDYSPNKKKKKK
LKDKKEKKAKRKKKDEDEDDNDDGCLKEPKSSGQLMAEWGLDDVDYLFSEEDYHTLTN
YKAFSQFLRPLIAKKNPKIPMSKMMTVLGAKWREFSANNPFKGSSAAAAAAAVAAAVE
TVTISPPLAVSPPQVPQPVPIRKAKTKEGKGPGVRKKIKGSKDGKKKGKGKKTAGLKF
RFGGISNKRKKGSSSEEDEREESDFDSASIHSASVRSECSAALGKKSKRRRKKKRIDD
GDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHCEKEGI
QWEPKDDDDEEEEGGCEEEEDDHMEFCRVCKDGGELLCCDACPSSYHLHCLNPPLPEI
PNGEWLCPRCTCPPLKGKVQRILHWRWTEPPAPFMVGLPGPDVEPSLPPPKPLEGIPE
REFFVKWAGLSYWHCSWVKELQLELYHTVMYRNYQRKNDMDEPPPFDYGSGDEDGKSE
KRKNKDPLYAKMEERFYRYGIKPEWMMIHRILNHSFDKKGDVHYLIKWKDLPYDQCTW
EIDDIDIPYYDNLKQAYWGHRELMLGEDTRLPKRLLKKGKKLRDDKQEKPPDTPIVDP
TVKFDKQPWYIDSTGGTLHPYQLEGLNWLRFSWAQGTDTILADEMGLGKTVQTIVFLY
SLYKEGHSKGPYLVSAPLSTIINWEREFEMWAPDFYVVTYTGDKESRSVIRENEFSFE
DNAIRSGKKVFRMKKEVQIKFHVLLTSYELITIDQAILGSIEWACLVVDEAHRLKNNQ
SKFFRVLNSYKIDYKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKE
DQIKKLHDLLGPHMLRRLKADVFKNMPAKTELIVRVELSQMQKKYYKFILTRNFEALN
SKGGGNQVSLLNIMMDLKKCCNHPYLFPVAAVEAPVLPNGSYDGSSLVKSSGKLMLLQ
KMLKKLRDEGHRVLIFSQMTKMLDLLEDFLEYEGYKYERIDGGITGGLRQEAIDRFNA
PGAQQFCFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIY
RFVTRASVEERITQVAKRKMMLTHLVVRPGLGSKSGSMTKQELDDILKFGTEELFKDD
VEGMMSQGQRPVTPIPDVQSSKGGNLAASAKKKHGSTPPGDNKDVEDSSVIHYDDAAI
SKLLDRNQDATDDTELQNMNEYLSSFKVAQYVVREEDGVEEVEREIIKQEENVDPDYW
EKLLRHHYEQQQEDLARNLGKGKRIRKQVNYNDASQEDQEWQDELSDNQSEYSIGSED
EDEDFEERPEGQSGRRQSRRQLKSDRDKPLPPLLARVGGNIEVLGFNARQRKAFLNAI
MRWGMPPQDAFNSHWLVRDLRGKSEKEFRAYVSLFMRHLCEPGADGAETFADGVPREG
LSRQHVLTRIGVMSLVRKKVQEFEHVNGKYSTPDLIPEGPEGKKSGEVISSDPNTPVP
ASPAHLLPAPLGLPDKMEAQLGYMDEKDPGAQKPRQPLEVQALPAALDRVESEDKHES
PASKERAREERPEETEKAPPSPEQLPREEVLPEKEKILDKLELSLIHSRGDSSELRPD
DTKAEEKEPIETQQNGDKEEDDEGKKEDKKGKFKFMFNIADGGFTELHTLWQNEERAA
VSSGKIYDIWHRRHDYWLLAGIVTHGYARWQDIQNDPRYMILNEPFKSEVHKGNYLEM
KNKFLARRFKLLEQALVIEEQLRRAAYLNMTQDPNHPAMALNARLAEVECLAESHQHL
SKESLAGNKPANAVLHKVLNQLEELLSDMKADVTRLPSMLSRIPPVAARLQMSERSIL
SRLTNRAGDPTIQQGAFGSSQMYSNNFGPNFRGPGPGGIVNYNQMPLGPYVTDI"
BASE COUNT 2076 a 2789 c 3013 g 1768 t
ORIGIN
1 tcgcccgccg cgcgcgccgg tccggcagcg cacgggttaa ggctggcacc gcgcccggcg
61 ggaggggggg cgcccacctc ccctcctccc cgcgccgggc atgcggggcc cagtgggcac
121 cgaggaggag ctgccgcggc tgttcgccga ggagatggag aatgaggacg agatgtcaga
181 agaagaagat ggtggtcttg aagccttcga tgactttttc cctgtggagc ccgtgagcct
241 tcctaagaag aagaaaccca agaagctcaa ggaaaacaag tgtaaaggga agcggaagaa
301 gaaagagggg agcaatgatg agctatcaga gaatgaagag gatctggaag agaagtcgga
361 gagtgaaggc agtgactact ccccgaataa aaagaagaag aagaaactca aggacaagaa
421 ggagaaaaaa gccaagcgaa aaaagaagga tgaggatgag gatgataatg atgatggatg
481 cttaaaggag cccaagtcct cggggcagct catggccgag tggggcctgg acgacgtgga
541 ctacctgttc tcggaggagg attaccacac gctgaccaac tacaaggcct tcagccagtt
601 cctcaggcca ctcattgcca agaagaaccc gaagatcccc atgtccaaaa tgatgaccgt
661 cctgggtgcc aagtggcggg agttcagcgc caacaacccc ttcaagggca gctccgcggc
721 agcagcggcg gcggcggtgg ctgcggctgt agagacggtc accatctccc ctccgctagc
781 cgtcagcccc ccgcaggtgc cccagcctgt gcctatccgc aaggccaaga ccaaggaggg
841 caaagggcct ggagtgagga agaagatcaa aggctccaaa gatgggaaga aaaagggcaa
901 agggaaaaag acggccgggc tcaagttccg cttcgggggg atcagcaaca agaggaagaa
961 aggctcctcg agtgaagaag atgagaggga ggagtcggac ttcgacagcg ccagcatcca
1021 cagtgcctcc gtgcgctccg aatgctctgc agccctgggc aagaagagca agaggaggcg
1081 caagaagaag aggattgatg atggtgacgg ctatgagaca gaccaccagg attactgtga
1141 ggtgtgccag cagggtgggg agatcatcct gtgcgacacc tgcccgaggg cctaccatct
1201 cgtatgcctg gacccagagc tggagaaggc tcccgagggc aagtggagct gcccccactg
1261 tgagaaggag gggatccagt gggagccgaa ggacgacgac gatgaagagg aggagggcgg
1321 ctgcgaggag gaggaggacg accacatgga gttctgccgc gtgtgcaagg acgggggcga
1381 gctgctctgc tgcgacgcct gcccctcctc ctaccacctg cattgcctca acccgccgct
1441 gcccgagatc ccaaacggtg aatggctctg cccgcgctgt acttgccccc cactgaaggg
1501 caaagtccag cggattctac actggaggtg gacggagccc cctgccccct tcatggtggg
1561 gctgccgggg cctgacgtgg agcccagcct ccctccacct aagcccctgg agggcatccc
1621 tgagagagag ttctttgtca agtgggcagg gctgtcctac tggcattgct cctgggtgaa
1681 ggagctacag ctggagctgt accacacggt gatgtatcgc aactaccaaa gaaagaacga
1741 catggatgag ccgcccccct ttgactacgg ctctggggat gaagacggca agagcgagaa
1801 gaggaagaac aaggaccccc tctatgccaa gatggaggag cgcttctacc gctatggcat
1861 caagccagag tggatgatga ttcaccgaat cctgaaccat agctttgaca agaaggggga
1921 tgtgcactac ctgatcaagt ggaaagacct gccctacgac cagtgcacct gggagatcga
1981 tgacatcgac atcccctact acgacaacct caagcaggcc tactggggcc acagggagct
2041 gatgctggga gaagacacca ggctgcccaa gaggctgctc aagaagggca agaagctgag
2101 ggacgacaag caggagaagc cgccggacac gcccattgtg gaccccacgg tcaagttcga
2161 caagcagcca tggtacatcg actccacagg cggcacactg cacccgtacc agctggaggg
2221 cctcaactgg ctgcgcttct cttgggccca gggcactgac accatcctgg ccgatgagat
2281 gggtctgggc aagacggtgc agaccatcgt gttcctttac tccctctaca aggagggcca
2341 ctccaaaggg ccctacctgg ttagcgcgcc cctctccacc atcatcaact gggaacgcga
2401 gtttgagatg tgggcgcccg acttctacgt ggtcacctac acgggggaca aggagagccg
2461 ctcggtgatt cgggagaacg agttttcctt tgaggacaac gccattcgga gtgggaagaa
2521 ggtattccgt atgaagaaag aagtgcagat caaattccac gtgctgctca cctcctatga
2581 gctcatcacc attgaccagg ccatcctggg ctccatcgag tgggcctgcc tggtggtaga
2641 tgaggcccac cgcctcaaga acaaccagtc caagtttttt agggtcttaa acagctacaa
2701 gattgattac aagctgctgc tgacagggac cccccttcag aacaacctgg aggagctgtt
2761 ccatctcctc aacttcctga ctccagagag gttcaacaac ctggagggct tcctggagga
2821 gtttgctgac atctccaagg aagaccagat caagaagctg catgacctgc tggggccgca
2881 catgctcagg cggctcaagg ctgacgtgtt caagaacatg ccggccaaga ccgagctcat
2941 tgtccgggtg gagctgagcc agatgcagaa gaagtactac aagttcatcc tcacacggaa
3001 ctttgaggca ctgaactcca aggggggcgg gaaccaagta tcgctgctca acatcatgat
3061 ggacctgaaa aagtgctgca accaccccta cctcttccct gtggctgccg tggaggcccc
3121 tgtcttgccc aatggctcct acgatggaag ctccctggtc aagtcttcag ggaagctcat
3181 gctgctacag aagatgctga agaaactgcg ggatgagggg caccgtgtgc tcatcttctc
3241 ccagatgacc aagatgctgg acctcctgga ggacttcctg gagtacgaag gctacaagta
3301 tgagcggatt gatggtggca tcaccggggg cctccggcag gaggcaatcg acagattcaa
3361 tgcccccggg gcccagcagt tctgcttcct cctctcaacc cgggcaggtg gtctgggcat
3421 caacctggcc acggcggaca ctgtcatcat ctacgactcg gactggaacc cgcacaatga
3481 catccaggcc ttcagccgcg cccaccgcat cggccagaac aagaaggtga tgatctaccg
3541 cttcgtgact cgggcctcgg tggaggagcg catcacgcag gtggccaagc gcaagatgat
3601 gctcacccac ctggtggtgc ggcccggcct cggctccaag tcggggtcca tgaccaagca
3661 ggagctggac gacatcctca agttcggcac ggaggaactc ttcaaggacg acgtggaggg
3721 catgatgtct cagggccaga ggccggtcac acccatccct gatgtccagt cctccaaagg
3781 ggggaacttg gccgccagtg caaagaagaa gcacggtagc accccgccag gtgacaacaa
3841 ggacgtggag gacagcagtg tgatccacta tgacgatgcg gccatctcca agctgctgga
3901 ccggaaccag gacgctacag atgacacgga gctacagaac atgaacgagt acctgagctc
3961 cttcaaggtg gcgcagtacg tggtgcgcga ggaggacggc gtggaggagg tggagcggga
4021 aatcatcaag caggaggaga acgtggaccc cgactactgg gagaagctgc tgcggcacca
4081 ctatgagcag cagcaggagg acctggcccg caacctgggc aagggcaagc gcatccgcaa
4141 gcaggtcaac tacaacgatg cctcccagga ggaccaggag tggcaggatg agctctctga
4201 taaccagtca gaatattcca ttggctctga ggatgaggat gaggactttg aagagaggcc
4261 ggaagggcag agtggacgac gacaatcccg gaggcagctg aagagtgaca gggacaagcc
4321 cctgcccccg cttctcgccc gagttggtgg caacatcgag gtgctgggct tcaatgcccg
4381 acagcggaag gcctttctga acgccatcat gcgctggggc atgcccccgc aggacgcctt
4441 caactcccac tggctggtgc gggaccttcg agggaagagc gagaaggagt ttagagccta
4501 tgtgtccctc ttcatgcggc acctgtgtga gccgggggcg gatggtgcag agaccttcgc
4561 agacggcgtg ccccgggagg gcctctccag gcagcacgtg ctgacccgca tcggggtcat
4621 gtcactagtt aggaagaagg ttcaggagtt tgagcatgtc aacgggaagt acagcacccc
4681 agacttgatc cctgaggggc ccgaggggaa gaagtcgggc gaggtgatct cctcggaccc
4741 caacacacca gtgcccgcca gccctgccca cctcctgcca gccccgctgg gcctgccaga
4801 caaaatggaa gcccagctgg gctacatgga tgagaaagac cccggggcac agaagccaag
4861 gcagcccctg gaagtccagg cccttccagc cgccttggat agagtggaga gtgaggacaa
4921 gcacgagagc ccagccagca aggagagagc ccgagaggag cggccagagg agacggagaa
4981 ggccccgccc tccccggagc agctgccgag agaggaggtg cttcctgaga aggagaagat
5041 cctggacaag ctggagctga gcttgatcca cagcagaggg gacagttccg aactcaggcc
5101 agatgacacc aaggctgagg agaaggagcc cattgaaaca cagcaaaatg gtgacaaaga
5161 ggaagatgac gaggggaaga aggaggacaa gaaggggaaa ttcaagttca tgttcaacat
5221 cgcggacggg ggcttcacgg agttgcacac gctgtggcag aacgaggagc gggctgctgt
5281 atcctctggg aaaatctacg acatctggca ccggcgccat gactactggc tgctggcggg
5341 catcgtgacg cacggctacg cccgctggca ggacatccag aatgacccac ggtacatgat
5401 cctcaacgag cccttcaagt ctgaggtcca caagggcaac tacctggaga tgaagaacaa
5461 gttcctggcc cgcaggttta agctgctgga gcaggcgttg gtcattgagg agcagctccg
5521 gagggccgcg tacctgaaca tgacgcagga ccccaaccac cccgccatgg ccctcaacgc
5581 ccgcctggct gaagtggagt gcctcgccga gagccaccag cacctgtcca aggagtccct
5641 tgctgggaac aagcctgcca atgccgtcct gcacaaggtc ctgaaccagc tggaggagct
5701 gctgagcgac atgaaggccg acgtgacccg gctgccatcc atgctgtccc gcatcccccc
5761 ggtggccgcc cggctgcaga tgtcggagcg cagcatcctg agccgcctga ccaaccgcgc
5821 cggggacccc accatccagc agggcgcttt cggctcctcc cagatgtaca gcaacaactt
5881 tgggcccaac ttccggggcc ctggaccggg agggattgtc aactacaacc agatgcccct
5941 ggggccctat gtgaccgata tctagccgtc ctcgagactt ccctgtgttg cagcgctcat
6001 ttccagctga gccacgcctg ccgggccacc tgcccgaccc acatgggaga gaaaagctgc
6061 caccttttta ggagccagcg ccaccttggg acaaaaaggg aaacctagta atgccatcac
6121 atggaggacg aggcccagct cagctgggcc agagcccaga agtgccacct catcataatt
6181 caagtgttct tccacacagc gttgccccca caaccacgcc ggacgtgccc cctcgccacc
6241 ttttccagac gacttcttag aagagatttc atttatttgt acatcttttg cactttccta
6301 ttgaagactt gaacacgttt gtcttgataa aagttggatg acgtatggaa gattcgaacc
6361 tgcagcactg atgtctcttt accgatgggt tccagaccca aggtagtcct ggcactgccc
6421 tgtggactca gcccagctgg ggaggacatg gcgcccggtg ccctaggagc cctcagtgtc
6481 ccctacctga cctgtctgca cctgtgtgac agccccttct gatttggccc cctgcccgct
6541 tggagcctcc cagcaccaga cagggcaggt ttggggagcc gctgtcgagc cctatggtga
6601 gaccctggct gacatttccc ctccttcctg ccaaggctgg aggccgccag gtgtttgctc
6661 tctccttgtg gggaggtgga tcctctgcca gcaggtgtct gtccccggcc cagcgcatct
6721 tgaaggccct ggactctgtt accagtgggg ggcctgtggc cccggctctt cacagcaggc
6781 agaagcgtat gatcccaggg agggtgggct gggggggggc cagcacttgc ctcggagcca
6841 ctgctgcgtt gggtttgcct tctgccagag gtgtggttaa gggcagtgat agctgcgccc
6901 cagcaaggag ggtcatgggc cctgagctgg cccaggagac cctggccctg ccctgtgccc
6961 tgggatgcct accctgccca cctccggagg tggaaccggg ctgcccctgg gggcctggac
7021 ttgtcccatt cccctgtccc tggaaaggcc ttcccggggg ctttttgcct gaggctgcac
7081 tcttggaagg tgtggggaga gttctgcctg gagggggact ggacccagtg ccctctgcag
7141 acccctccca gccgcagcac caagggcttg ctgccttgtt tcctgccagg agcgccctga
7201 catcccaaaa ccatcttccc acatgtgggt tgttggaatc ccacccactc ccccggaccc
7261 tgcccctcca agttggggac ggagatgggg agcaggtcag gccctcccta ggcctgtttg
7321 tgtgtgatcc ttctcctggc cccaggtcga cctggaaggc gtttctgagt cttgtactgg
7381 gaccttccca gggaaggtgc cttggggtgc agaatcctgg gaatgttagg aaagggctgc
7441 gtgaaaaacc cagctgggcc tggggtggag gtgcacacgg gctggggctc agctccttgg
7501 agagggcctg cctgggactg agggggccag ggctgggtca ggattcacca gcttgtgttg
7561 cagacactgg agcaattgcc tggccctccc taagccctat atgcctcact cataatgagg
7621 ctgtctctga accccggagg gcgggaccta caagtccttc ctcttggcgc attcccacac
7681 tccagtctgg atccaggtct gcaaggccag cccgaccctg acactgcacg tgggcgtagt
7741 ggggagcacc ctggagtgga gatgattgtc agcgggctca catgttatgg ttcatccaca
7801 tgcgtgttgt gtgctctgcg gtgcctcctg gcaaagggtc ctggctcggg tcagaagctc
7861 actcccgtgc cctcgtcccc aaacaagcag tggcaagcac tggggttggc cctcgttggg
7921 agcagtgccc accttccttg gcccacagca gataggtccc gagcagcagg actggaggcc
7981 tgtggcggtc agggcagggg tctgtgtctc caccccaagg gctgatggtc cctcccctgt
8041 gcgccttcct ctcaggcagg cttgctctgt cccttcctct ctgcttccct cccaggcctc
8101 gccagggctc ccttctcctc tgcctggtta gactcgggca cccaggaaag cctggccagg
8161 gctcctttgg gcctgggccc cctgcactgc ctggtccaga aggggtggtg ctgtccgtgg
8221 ccagcacccc ggggcccggg aggggtgggc tactagagtc agagcgggtt tggggctgac
8281 cagtttggga gaggagaaaa gatctgagaa tgtccttctt ggtttgtcag tcatctctgc
8341 caaaagtggt gatggtggtg tccgtatgtt tggcgtcttt gggctgggtt tggtttttgc
8401 tgctggtaga atcagggtcc tcgggcatga acgcgagccc aaagtgccag tctgcgattg
8461 gaaatttcca gccactttaa gccagtgctg agtagggctt ctgcagagcc atgtttgagc
8521 caaggtcttg gaaggcattg ccccatgggc tcaggtgact cggggtggag tgagcacgtc
8581 tgcagggccc tctcatacac gcctgaggca gaagcagcgt cccccgtgaa agccaccttc
8641 cgaagctcct gcgttttttg caaacttggc ttcccccagg ggcaggctgg actttccctg
8701 ccccctatga ttgaagtcct cctgcttttg ggggctgcct tcccagagtc ccccgggtgc
8761 tcccctgccg aggtcaggag ctgaccaagc cttggcccgg tgacacctgc agccctcact
8821 cctgtcatcc caggacactt gaggcccaag gaggtggagt ggagagtggg ctcgggtaca
8881 tgggagccag aagccagatg gacttggtca agtgttggtc acttggagcc tccagtgtgc
8941 gtcagggtct gtgggcaggg gacagggcgt gggtgggggc cgaggctggc acgcccctct
9001 gccctcaccg tcttggtgac ctggcctcgg cccctccccc aagtctcttc tgtgcaaggc
9061 ccgcctcggc ctcggcagct ggttcctgtc ccgttttctg tgtctgaaag tttacaggtt
9121 gtggtgcatc agcccaaact cactggcgtt gtgttttttt tttctttaat tttcagattt
9181 tttttttaaa caaagtattt ttttaggtgc gataacccag aaagggcccg ttgggtgtgt
9241 gtgtgtgtcc tgaactcctc aagcagcgat tggagcccaa gcacccctgg agaggaaggg
9301 agggtcccca ctggcccgtg gggtctgagt tcaggggtgt ggagggagca gactccaccg
9361 gcccaggccc agctaagagg gggccgaccc ctttccccag gcacagcccc aggctggcaa
9421 agggagggcc ctgggctggg tgcagggcgc gccaggagtc ccagccaggg tggccccggc
9481 gggggcgggt ccagctttgg aagccaggct cccctgtgag ccgtggcttg tctggtcttc
9541 gcccacggga ggctggacag aggctgtagc caacacaatc acctttactt tgtactctgt
9601 gtgtatgttt tggttttctg tgttttaata aatcctttgg gaaagg
//