LOCUS AF423307 4875 bp mRNA linear HUM 22-OCT-2002
DEFINITION Homo sapiens ATP-binding cassette sub-family A member 9 (ABCA9)
mRNA, complete cds.
ACCESSION AF423307
VERSION AF423307.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4875)
AUTHORS Piehler,A., Kaminski,W.E., Wenzel,J.J., Langmann,T. and Schmitz,G.
TITLE Molecular structure of a novel cholesterol-responsive A subclass
ABC transporter, ABCA9
JOURNAL Biochem. Biophys. Res. Commun. 295 (2), 408-416 (2002)
PUBMED 12150964
REFERENCE 2 (bases 1 to 4875)
AUTHORS Kaminski,W.E. and Piehler,A.
TITLE Direct Submission
JOURNAL Submitted (25-SEP-2001) Institute for Clinical Chemistry and
Laboratory Medicine, University of Regensburg Medical School, FJS
Allee 11, Regensburg 93042, Germany
FEATURES Location/Qualifiers
source 1..4875
/db_xref="H-InvDB:HIT000079419"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
/map="17q24.2"
gene 1..4875
/gene="ABCA9"
CDS 1..4875
/gene="ABCA9"
/note="ABC transporter"
/codon_start=1
/product="ATP-binding cassette sub-family A member 9"
/protein_id="AAN32751.1"
/translation="MSKRRMSVGQQTWALLCKNCLKKWRMKRQTLLEWLFSFLLVLFL
YLFFSNLHQVHDTPQMSSMDLGRVDSFNDTNYVIAFAPESKTTQEIMNKVASAPFLKG
RTIMGWPDEKSMDELDLNYSIDAVRVIFTDTFSYHLKFSWGHRIPMMKEHRDHSAHCQ
AVNEKMKCEGSEFWEKGFVAFQAAINAAIIEIATNHSVMEQLMSVTGVHMKILPFVAQ
GGVATDFFIFFCIISFSTFIYYVSVNVTQERQYITSLMTMMGLRESAFWLSWGLMYAG
FILIMATLMALIVKSAQIVVLTGFVMVFTLFLLYGLSLITLAFLMSVLIKKPFLTGLV
VFLLIVFWGILGFPALYTRLPAFLEWTLCLLSPFAFTVGMAQLIHLDYDVNSNAHLDS
SQNPYLIIATLFMLVFDTLLYLVLTLYFDKILPAEYGHRCSPLFFLKSCFWFQHGRAN
HVVLENETDSDPTPNDCFEPVSPEFCGKEAIRIKNLKKEYAGKCERVEALKGVVFDIY
EGQITALLGHSGAGKTTLLNILSGLSVPTSGSVTVYNHTLSRMADIENISKFTGFCPQ
SNVQFGFLTVKENLRLFAKIKGILPHEVEKEVQRVVQELEMENIQDILAQNLSGGQNR
KLTFGIAILGDPQVLLLDEPTAGLDPLSRHRIWNLLKEGKSDRVILFSTQFIDEADIL
ADRKVFISNGKLKCAGSSLFLKKKWGIGYHLSLHLNERCDPESITSLVKQHISDAKLT
AQSEEKLVYILPLERTNKFPELYRDLDRCSNQGIEDYGVSITTLNEVFLKLEGKSTID
ESDIGIWGQLQTDGAKDIGSLVELEQVLSSFHETRKTISGVALWRQQVCAIAKVRFLK
LKKERKSLWTILLLFGISFIPQLLEHLFYESYQKSYPWELSPNTYFLSPGQQPQDPLT
HLLVINKTGSTIDNFLHSLRRQNIAIEVDAFGTRNGTDDPSYNGAIIVSGDEKDHRFS
IACNTKRLNCFPVLLDVISNGLLGIFNSSEHIQTDRSTFFEEHMDYEYGYRSNTFFWI
PMAASFTPYIAMSSIGDYKKKAHSQLRISGLYPSAYWFGQALVDVSLYFLILLLMQIM
DYIFSPEEIIFIIQNLLIQILCSIGYVSSLVFLTYVISFIFRNGRKNSGIWSFFFLIV
VIFSIVATDLNEYGFLGLFFGTMLIPPFTLIGSLFIFSEISPDSMDYLGASESEIVYL
ALLIPYLHFLIFLFILRCLEMNCRKKLMRKDPVFRISPRSNAIFPNPEEPEGEEEDIQ
MERMRTVNAMAVRDFDETPVIIASCLRKEYAGKKKNCFSKRKKKIATRNVSFCVKKGE
VIGLLGHNGAGKSTTIKMITGDTKPTAGQVILKGSGGGEPLGFLGYCPQENALWPNLT
VRQHLEVYAAVKGLRKGDAMIAITRLVDALKLQDQLKAPVKTLSEGIKRKLCFVLSIL
GNPSVVLLDEPSTGMDPEGQQQMWQVIRATFRNTERGALLTTHYMAEAEAVCDRVAIM
VSGRLRCIGSIQHLKSKFGKDYLLEMKLKNLAQMEPLHAEILRLFPQAAQQERFSSLM
VYKLPVEDVRPLSQAFFKLEIVKQSFDLEEYSLSQSTLEQVFLELSKEQELGDLEEDF
DPSVKWKLLLQEEP"
BASE COUNT 1396 a 964 c 1096 g 1419 t
ORIGIN
1 atgagcaaga gacgcatgag cgtgggtcag caaacatggg ctcttctctg caagaactgt
61 ctcaaaaaat ggagaatgaa aagacagacc ttgttggaat ggctcttttc atttcttctg
121 gtactgtttc tgtacctatt tttctccaat ttacatcaag ttcatgacac tcctcaaatg
181 tcttcaatgg atctgggacg tgtagatagt tttaatgata ctaattatgt tattgcattt
241 gcacctgaat ccaaaactac ccaagagata atgaacaaag tggcttcagc cccattccta
301 aaaggaagaa caatcatggg gtggcctgat gaaaaaagca tggatgaatt ggatttgaac
361 tattcaatag acgcagtgag agtcatcttt actgatacct tctcctacca tttgaagttt
421 tcttggggac atagaatccc catgatgaaa gagcacagag accattcagc tcactgtcaa
481 gcagtgaatg aaaaaatgaa gtgtgaaggt tcagagttct gggagaaagg ctttgtagct
541 tttcaagctg ccattaatgc tgctatcata gaaatcgcaa caaatcattc agtgatggaa
601 cagctgatgt cagttactgg tgtacatatg aagatattac cttttgttgc ccaaggagga
661 gttgcaactg attttttcat tttcttttgc attatttctt tttctacatt tatatactat
721 gtatcagtca atgttacaca agaaagacaa tacattacgt cattgatgac aatgatggga
781 ctccgagagt cagcattctg gctttcctgg ggtttgatgt atgctggctt catccttatc
841 atggccactt taatggctct tattgtaaaa tctgcacaaa ttgtcgtcct gactggtttt
901 gtgatggtct tcaccctctt tctcctctat ggcctgtctt tgataacttt agctttcctg
961 atgagtgtgt tgataaagaa acctttcctt acgggcttgg ttgtgtttct ccttattgtc
1021 ttttggggga tcctgggatt cccagcattg tatacacgtc ttcctgcatt tttggaatgg
1081 actttgtgtc ttcttagccc ctttgccttc actgttggga tggcccagct tatacatttg
1141 gactatgatg tgaattctaa tgcccacttg gattcttcac aaaatccata cctcataata
1201 gctactcttt tcatgttggt ttttgacacc cttctgtatt tggtattgac attatatttt
1261 gacaaaattt tgcccgctga atatggacat cgatgttctc ccttgttttt cctgaaatcc
1321 tgtttttggt ttcaacacgg aagggctaat catgtggtcc ttgagaatga aacagattct
1381 gatcctacac ctaatgactg ttttgaacca gtgtctccag aattctgtgg gaaagaagcc
1441 atcagaatca aaaatcttaa aaaagaatat gcagggaagt gtgagagagt agaagctttg
1501 aaaggtgtgg tgtttgacat atatgaaggc cagatcactg ccctccttgg tcacagtgga
1561 gctggaaaaa ctaccctgtt aaacatactt agtgggttgt cagttccaac atcaggttca
1621 gtcactgtct ataatcacac actttcaaga atggctgata tagaaaatat cagcaagttc
1681 actggatttt gtccacaatc caatgtgcaa tttggatttc tcactgtgaa agaaaacctc
1741 aggctgtttg ctaaaataaa agggattttg ccacatgaag tggagaaaga ggtacaacga
1801 gttgtacagg aattagaaat ggaaaatatt caagacatcc ttgctcaaaa cttaagtggt
1861 ggacaaaata ggaaactaac ttttgggatt gccattttag gagatcctca agttttgcta
1921 ttggatgaac cgactgctgg attggatcct ctttcaaggc accgaatatg gaatctcctg
1981 aaagagggga aatcagacag agtaattctc ttcagcaccc agtttataga tgaggctgac
2041 attctggcgg acaggaaggt gttcatatcc aatgggaagc tgaagtgtgc aggctcttct
2101 ctgttcctta agaagaaatg gggcataggc taccatttaa gtttgcatct gaatgaaagg
2161 tgtgatccag agagtataac atcactggtt aagcagcaca tctctgatgc caaattgaca
2221 gcacaaagtg aagaaaaact tgtatatatt ttgcctttgg aaaggacaaa caaatttcca
2281 gaactttaca gggatcttga tagatgttct aaccaaggca ttgaggatta tggtgtttcc
2341 ataacaactt tgaatgaggt gtttctgaaa ttagaaggaa aatcaactat tgatgaatca
2401 gatattggaa tttggggaca attacaaact gatggggcaa aagatatagg aagccttgtt
2461 gagctggaac aagttttgtc ttccttccac gaaacaagga aaacaatcag tggcgtggcg
2521 ctctggaggc agcaggtctg tgcaatagca aaagttcgct tcctaaagtt aaagaaagaa
2581 agaaaaagcc tgtggactat attattgctt tttggtatta gctttatccc tcaacttttg
2641 gaacatctat tctacgagtc atatcagaaa agttacccgt gggaactgtc tccaaataca
2701 tacttcctct caccaggaca acaaccacag gatcctctga cccatttact ggtcatcaat
2761 aagacagggt caaccattga taacttttta cattcactga ggcgacagaa catagctata
2821 gaagtggatg cctttggaac tagaaatggc acagatgacc catcttacaa tggtgctatc
2881 attgtgtcag gtgatgaaaa ggatcacaga ttttcaatag catgtaatac aaaacggctg
2941 aattgctttc ctgtcctcct ggatgtcatt agcaatggac tacttggaat ttttaattcg
3001 tcagaacaca ttcagactga cagaagcaca ttttttgaag agcatatgga ttatgagtat
3061 gggtaccgaa gtaacacctt cttctggata ccgatggcag cctctttcac tccatacatt
3121 gcaatgagca gcattggtga ctacaaaaaa aaagctcatt cccagctacg gatttcaggc
3181 ctctaccctt ctgcatactg gtttggccaa gcactggtgg atgtttccct gtactttttg
3241 atcctcctgc taatgcaaat aatggattat atttttagcc cagaggagat tatatttata
3301 attcaaaacc tgttaattca aatcctgtgt agtattggct atgtctcatc tcttgttttc
3361 ttgacatatg tgatttcatt catttttcgc aatgggagaa aaaatagtgg catttggtca
3421 tttttcttct taattgtggt catcttctcg atagttgcta ctgatctaaa tgaatatgga
3481 tttctagggc tattttttgg caccatgtta atacctccct tcacattgat tggctctcta
3541 ttcatttttt ctgagatttc tcctgattcc atggattact taggagcttc agaatctgaa
3601 attgtatacc tggcactgct aataccttac cttcattttc tcatttttct tttcattctg
3661 cgatgcctag aaatgaactg caggaagaaa ctaatgagaa aggatcctgt gttcagaatt
3721 tctccaagaa gcaacgctat ttttccaaac ccagaagagc ctgaaggaga ggaggaagat
3781 atccagatgg aaagaatgag aacagtgaat gctatggctg tgcgagactt tgatgagaca
3841 cccgtcatca ttgccagctg tctacggaag gaatatgcag gcaaaaagaa aaattgcttt
3901 tctaaaagga agaaaaaaat tgccacaaga aatgtctctt tttgtgttaa aaaaggtgaa
3961 gttataggac tgttaggaca caatggagct ggtaaaagta caactattaa gatgataact
4021 ggagacacaa aaccaactgc aggacaggtg attttgaaag ggagcggtgg aggggaaccc
4081 ctgggcttcc tggggtactg ccctcaggag aatgcgctgt ggcccaacct gacagtgagg
4141 cagcacctgg aggtgtacgc tgccgtgaaa ggtctcagga aaggggacgc aatgatcgcc
4201 atcacacggt tagtggatgc gctcaagctg caggaccagc tgaaggctcc cgtgaagacc
4261 ttgtcagagg gaataaagcg aaagctgtgc tttgtgctga gcatcctggg gaacccgtca
4321 gtggtgcttc tggatgagcc gtcgaccggg atggaccccg aggggcagca gcaaatgtgg
4381 caggtgattc gggccacctt tagaaacacg gagaggggcg ccctcctgac cacccactac
4441 atggcagagg ctgaggcggt gtgtgaccga gtggccatca tggtgtcagg aaggctgaga
4501 tgtattggtt ccatccaaca cctgaaaagc aaatttggca aagactacct gctggagatg
4561 aagctgaaga acctggcaca aatggagccc ctccatgcag agatcctgag gcttttcccc
4621 caggctgctc agcaggaaag gttctcctcc ctgatggtct ataagttgcc tgttgaggat
4681 gtgcgacctt tatcacaggc tttcttcaaa ttagagatag ttaaacagag tttcgacctg
4741 gaggagtaca gcctctcaca gtctaccctg gagcaggttt tcctggagct ctccaaggag
4801 caggagctgg gtgatcttga agaggacttt gatccctcgg tgaagtggaa actcctcctg
4861 caggaagagc cttaa
//