LOCUS AF411226 3611 bp mRNA linear HUM 15-NOV-2006
DEFINITION Homo sapiens astrocyte elevated gene-1 AEG1 mRNA, complete cds.
ACCESSION AF411226
VERSION AF411226.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3611)
AUTHORS Lee,S.G., Su,Z.Z., Emdad,L., Sarkar,D. and Fisher,P.B.
TITLE Astrocyte elevated gene-1 (AEG-1) is a target gene of oncogenic
Ha-ras requiring phosphatidylinositol 3-kinase and c-Myc
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 103 (46), 17390-17395 (2006)
PUBMED 17088530
REFERENCE 2 (bases 1 to 3611)
AUTHORS Kang,D.-C., Su,Z. and Fisher,P.B.
TITLE Astrocyte elevated gene-1(AEG-1), a putative membrane-attached
GTPase induced by HIV infection in astrocyte
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 3611)
AUTHORS Kang,D.-C., Su,Z. and Fisher,P.B.
TITLE Direct Submission
JOURNAL Submitted (17-AUG-2001) Urology, Columbia University, P&S, 630 West
168th Street, New York, NY 10032, USA
FEATURES Location/Qualifiers
source 1..3611
/db_xref="H-InvDB:HIT000079233"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="8"
/map="8q23"
/cell_type="astrocyte"
/dev_stage="fetal"
CDS 220..1968
/note="putative membrane-bound GTPase"
/codon_start=1
/product="astrocyte elevated gene-1 AEG1"
/protein_id="AAO65771.1"
/translation="MAARSWQDELAQQAEEGSARLREMLSVGLGFLRTELGLDLGLEP
KRYPGWVILVGTGALGLLLLFLLGYGWAAACAGARKKRRSPPRKREEAAAVPAAAPDD
LALLKNLRSEEQKKKNRKKLSEKPKPNGRTVEVAEGEAVRTPQSVTAKQPPEIDKKNE
KSKKNKKKSKSDAKAVQNSSRHDGKEVDEGAWETKISHREKRQQRKRDKVLTDSGSLD
STIPGIENTITVTTEQLTTASFPVGSKKNKGDSHLNVQVSNFKSGKGDSTLQVSSGLN
ENLTVNGGGWNEKSVKLSSQISAGEEKWNSVSPASAGKRKTEPSAWSQDTGDANTNGK
DWGRSWSDRSIFSGIGSTAEPVSQSTTSDYQWDVSRNQPYIDDEWSGLNGLSSADPNS
DWNAPAEEWGNWVDEERASLLKSQEPIPDDQKVSDDDKEKGEGALPTGKSKKKKKKKK
KQGEDNSTAQDTEELEKEIREDLPVNTSKTRPKQEKAFSLKTISTSDPAEVLVKNSQP
IKTLPPATSTEPSVILSKSDSDKSSSQVPPILQETDKSKSNTKQNSVPPSQTKSETSW
ESPKQIKKKKKARRET"
misc_feature 412..444
/note="prokaryotic membrane lipoprotein lipid attachment
site; other site"
misc_feature 1522..1545
/note="ATP/GTP-binding site motif A"
BASE COUNT 1123 a 722 c 804 g 962 t
ORIGIN
1 tcctggcggc ggcggagtga ggctgacagc ggggaacctg ggagacccct ccgccctccc
61 cgcggtggca gcggccgatc cccggctccg gcgcgaggga cggccgcgat gcgctcggcc
121 tgaggttacc cggcccggcc cttcctcgct tccctcgact attccactgc gtctccgcgc
181 cccggcgtca tcctgcgagt ccctctgacg ggagggaaga tggctgcacg gagctggcag
241 gacgagctgg cccagcaggc cgaggagggc tcggcccggc tgcgggaaat gctctcggtc
301 ggcctaggct ttctgcgcac cgagctgggc ctcgacctgg ggctggagcc gaaacggtac
361 cccggctggg tgatcctggt gggcactggc gcgctcgggc tgctgctgct gtttctgctg
421 ggctacggct gggccgcggc ttgcgccggc gcccgcaaaa agcggaggag cccgccccgc
481 aagcgggagg aggcggcggc cgtgccggcc gcggcccccg acgacctggc cttgctgaag
541 aatctccgga gcgaggaaca gaagaagaag aaccggaaga aactgtccga gaagcccaaa
601 ccaaatgggc ggactgttga agtggctgag ggtgaagctg ttcgaacacc tcaaagtgta
661 acagcaaagc agccaccaga gattgacaag aaaaatgaaa agtcaaagaa aaataagaag
721 aaatcaaagt cagatgctaa agcagtgcaa aacagttcac gccatgatgg aaaggaagtt
781 gatgaaggag cctgggaaac taaaattagt cacagagaga aacgacagca gcgtaaacgt
841 gataaggtgc tgactgattc tggttcattg gattcaacta tccctgggat agaaaatacc
901 atcacagtta ccaccgagca acttacaacc gcatcatttc ctgttggttc caagaagaat
961 aaaggtgatt ctcatctaaa tgttcaagtt agcaacttta aatctggaaa aggagattct
1021 acacttcagg tttcttcagg attgaatgaa aacctcactg tcaatggagg aggctggaat
1081 gaaaagtctg taaaactctc ctcacagatc agtgcaggtg aggagaagtg gaactccgtt
1141 tcacctgctt ctgcaggaaa gaggaaaact gagccatctg cctggagtca agacactgga
1201 gatgctaata caaatggaaa agactgggga aggagttgga gtgaccgttc aatattttct
1261 ggcattgggt ctactgctga gccagtttct cagtctacca cttctgatta tcagtgggat
1321 gttagccgta atcaacccta tatcgatgat gaatggtctg ggttaaatgg tctgtcttct
1381 gctgatccca actctgattg gaatgcacca gcagaagagt ggggcaattg ggtagacgaa
1441 gaaagagctt cacttctaaa gtcccaggaa ccaattcctg atgatcaaaa ggtctcagat
1501 gatgataaag aaaagggaga gggagctctt ccaactggga aatccaaaaa gaaaaaaaag
1561 aaaaagaaga agcaaggtga agataactct actgcacagg acacagaaga attagaaaaa
1621 gagattagag aagaccttcc agtgaatacc tctaaaaccc gtccaaaaca ggaaaaagct
1681 ttttccttga agaccataag cactagtgat ccagccgaag tactcgtcaa aaatagccag
1741 cctatcaaga ctcttccacc tgctacttct accgagccat ctgtaatctt atcaaaaagt
1801 gattctgaca agagctcttc ccaagtgccg ccaatactac aagagacaga taaatccaag
1861 tcaaatacca agcaaaatag tgtgcctcct tcacagacca agtctgaaac tagctgggaa
1921 tctcccaaac aaataaaaaa gaagaaaaaa gccagacgag aaacgtgaaa ttttttttcc
1981 tgaattggac atgtgtttgc aaacacttgt cttgaagatt atgctgttta tgcaataatt
2041 tgtgaacatg tacagagttt tatataaatt taaaccaatt tttaaaacaa aactgcggac
2101 accaccataa aaatggaatc aaaagaaagt taatttatga aattaagagg tcagcagaat
2161 atactcagtg atggaagaca cttgggaaag tctttttaat agaacaagaa cgatcttaat
2221 ttaagaatat tatcctggtt taacaacagt gccctgttta caacagattg tgccctatct
2281 catctgcagc cgaggaataa aggattctga ttagaaagag ggttgcctac agattagtaa
2341 gcaattcctt ggatcttatg cacagaactt gtaccatttg aatctgtttt atgcttaaat
2401 caaagtgctt tgatcaaatg cataacctgc catatcttta catatttgtt ggtagcaatt
2461 tgtattaaag aaatcacaag tgcaaataaa aagtcattta tcatttgttt aactaaactg
2521 tcatggttta gtttacaatt tttaaaaagt tcttaaaata ctgaaaatgc agttgacact
2581 tgtgtatggc ttatgaagtt atttttgata gtcttacatt acttgaattg ttcaaagtac
2641 agtatatttt aaattaagaa aagtgaacta tatgtatttg ttttatacat ttaaggctta
2701 gactcataaa taatgctatt gtttatgatt tgaaaacttt caggcaaaat ccaatttaca
2761 tttttccctt ccctagcaat tacttttttc cagcttcaac tcttcttagt tactaatact
2821 ttgttgactt taaaaatgaa atcattcaca aacttttggt atatgatgga gaatgaaaaa
2881 ctagagtcag acagctttaa ttgacattgt caacacctcc agttatcagg aatacatttt
2941 tttactgcct taacctgtag tgcgtagaat atgcatcaat ttcttgaagg agattcatgt
3001 ttttataaga attttcatgt aattattgca attgtggtca aataaggaac gtttcctgct
3061 tgaaattata ttgatttaaa tgatgtgtga gatgtttcac cattttcagg cactgtgtaa
3121 ttctattgta ataaactggc aggtatcttt gtaactataa atagtgcatg ctcagccatg
3181 tacactgtaa atagccttta ccaaacgtgt ttgacaagga ccataattaa catcacttag
3241 tgaattgtga taaagaaaaa aaagccatga tttattcgat gtgattggct tgtttttatg
3301 tggcgccaag aacgaacctg tttaacagct gtaaccaatg gtactgatct atccatccaa
3361 tgttgtcatt atatttgact gtggttcaac agtattgcgt tgtcagacta ggaaagctaa
3421 acgaacaaaa tggttttagt tttgctgaag actggcctta ttaatggaca gctttcctaa
3481 caagagatta ttaactttta tcaggtgtta acatctgttt caggaacatg gcagtatgtt
3541 tacatgtcag aagttttgtt taattctatg gtatttctaa attgacttgt ttaaataaat
3601 tcagcaaatg g
//