LOCUS AF411122 3290 bp mRNA linear HUM 19-FEB-2002
DEFINITION Homo sapiens importin 4 mRNA, complete cds.
ACCESSION AF411122
VERSION AF411122.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3290)
AUTHORS Jakel,S., Mingot,J.M., Schwarzmaier,P., Hartmann,E. and Gorlich,D.
TITLE Importins fulfil a dual function as nuclear import receptors and
cytoplasmic chaperones for exposed basic domains
JOURNAL EMBO J. 21 (3), 377-386 (2002)
PUBMED 11823430
REFERENCE 2 (bases 1 to 3290)
AUTHORS Schwarzmaier,P., Hartmann,E. and Goerlich,D.
TITLE Direct Submission
JOURNAL Submitted (16-AUG-2001) Institut fuer Biologie, Universitaet
Luebeck, Ratzeburger Allee 160, Luebeck 23538, Germany
FEATURES Location/Qualifiers
source 1..3290
/db_xref="H-InvDB:HIT000079227"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 3..3248
/note="nuclear import receptor"
/codon_start=1
/product="importin 4"
/protein_id="AAL78660.1"
/translation="MESAGLEQLLRELLLPDTERIRRATEQLQIVLRAPAALPALCDL
LASAADPQIRQFAAVLTRRRLNTRWRRLAAEQRESLKSLILTALQRETEHCVSLSLAQ
LSATIFRKEGLEAWPQLLQLLQHSTHSPHSPEREMGLLLLSVVVTSRPEAFQPHHREL
LRLLNETLGEVGSPGLLFYSLRTLTTMAPYLSTEDVPLARMLVPKLIMAMQTLIPIDE
AKACEALEALDELLESEVPVITPYLSEVLTFCLEVARNVALGNAIRIRILCCLTFLVK
VKSKALLKNRLLPPLLHTLFPIVAAEPPPGQLDPEDQDSEEEELEIELMGETPKHFAV
QVVDMLALHLPPEKLCPQLMPMLEEALRSESPYQRKAGLLVLAVLSDGAGDHIRQRLL
PPLLQIVCKGLEDPSQVVRNAALFALGQFSENLQPHISSYSREVMPLLLAYLKSVPLG
HTHHLAKACYALENFVENLGPKVQPYLPELMECMLQLLRNPSSPRAKELAVSALGAIA
TAAQVSLLPYFPAIMEHLREFLLTGREDLQPVQIQSLETLGVLARAVGEPMRPLAEEC
CQLGLGLCDQVDDADLRRCTYSLFAALSGLMGEGLAPHLEQITTLMLLSLRSTEGIVP
QYDGSSSFLLFDDESDGEEEEELMDEDVEEEDDSEISGYSVENAFFDEKEDTCAAVGE
ISVNTSVAFLPYMESVFEEVFKLLECPHLNVRKAAHEALGQFCCALHKACQSCPSEPN
TAALQAALARVVPSYMQAVNRERERQVVMAVLEALTGVLRSCGTLTLKPPGRLAELCG
VLKAVLQRKTACQDTDEEEEEEDDDQAEYDAMLLEHAGEAIPALAAAAGGDSFAPFFA
GFLPLLVCKTKQGCTVAEKSFAVGTLAETIQGLGAASAQFVSRLLPVLLSTAQEADPE
VRSNAIFGMGVLAEHGGHPAQEHFPKLLGLLFPLLARERHDRVRDNICGALARLLMAS
PTRKPEPQVLAALLHALPLKEDLEEWVTIGRLFSFLYQSSPDQVIDVAPELLRICSLI
LADNKIPPDTKAALLLLLTFLAKQHTDSFQAALGSLPVDKAQELQAVLGLS"
BASE COUNT 647 a 987 c 984 g 672 t
ORIGIN
1 ccatggagtc agccgggcta gagcagctcc tacgggagct gctgctaccg gacaccgagc
61 gcatccgtcg ggccacggaa cagctccaga tcgttcttcg ggcccccgcc gctttgccgg
121 ctctctgcga cctgctagcc tcggcggccg acccccagat ccgccagttt gcggccgtgc
181 tgacccgcag acgactgaac acccgctggc gacggctggc ggcggagcaa cgggagagcc
241 tcaagtccct gatcctgacg gccctgcaga gagaaacaga gcactgtgtg agcctcagcc
301 tggcccagct ctcagccacc atttttcgaa aggaaggctt ggaggcctgg ccacagcttt
361 tgcagctgct tcagcacagt acccacagcc cccacagccc agagagagag atggggcttt
421 tgctgctaag tgtggtggtg acctcccggc ccgaggcctt ccaaccccac caccgggagc
481 ttcttcggct tctgaatgag actcttggtg aggtgggctc tcctgggctg ctcttctact
541 ccctgcgcac tctgaccacc atggctccct acctcagcac tgaagatgtg cctctcgctc
601 ggatgttggt gcccaagctg atcatggcca tgcagactct gatccccata gatgaggcaa
661 aggcctgtga ggcccttgag gctttggatg aactgttgga gtcagaggtg ccggtcatca
721 ccccctacct ctctgaagtc ctcacattct gcctggaggt agctagaaat gtggccctgg
781 gcaatgcgat acgcatacgt attctctgct gcctcacttt cttggtcaaa gtcaagagca
841 aggccttact gaagaatcgt ctcctgccac ccttgctgca cacccttttc cccattgtgg
901 ctgctgagcc cccaccaggc cagttggatc ccgaggacca ggattcagaa gaggaagagt
961 tggagattga gctgatgggg gagactccca agcatttcgc tgtacaagtt gtggacatgc
1021 tggcactaca cctgcccccc gagaagctct gtccccagct gatgcccatg ttggaagagg
1081 ctttgcggag cgagagccca taccagcgca aagctggact cctggtgctg gccgtgctgt
1141 ctgacggagc tggcgaccac atcaggcaga gactgctgcc cccactgctg cagattgtgt
1201 gcaagggcct ggaggacccc tcgcaagttg tacgcaatgc tgcgctgttt gccctgggcc
1261 agttctcaga aaacctacag ccccatatca gcagctattc aagggaggta atgccactgc
1321 tcctcgccta cttgaagtcg gtgcctcttg gacacacaca ccacctagcc aaggcctgct
1381 atgccctgga gaattttgtg gagaacctag ggcccaaggt gcagccctac cttccggagc
1441 ttatggaatg catgctgcag cttctgagga accccagcag tccccgggcc aaggagctgg
1501 ctgtgagcgc cctgggagcc attgctacgg ctgcccaggt ctcgctgctg ccctacttcc
1561 ctgccatcat ggagcacctg cgggaattcc tgttaacagg ccgtgaggac cttcagcctg
1621 tgcagatcca gagcctggag acactggggg tgctggcacg agcagtgggg gagcccatga
1681 ggccgctggc tgaggaatgc tgccagctgg gtctgggcct ctgcgaccag gtagacgacg
1741 ctgacttgcg gcgctgcacg tacagcctat ttgcagcctt atcgggtctg atgggtgagg
1801 gcctggcgcc ccacttggaa cagatcacca cgctcatgct gctgtcactg cgttccaccg
1861 agggcattgt gcctcagtat gacgggagca gctccttcct tctgtttgac gatgagagtg
1921 atggggaaga agaggaggag ctcatggatg aggatgtgga agaagaggat gactcagaga
1981 tctcagggta cagcgtggag aatgccttct tcgatgagaa ggaagacacc tgtgctgccg
2041 tgggggagat ctctgtgaac accagtgtgg ccttccttcc atacatggaa agtgtctttg
2101 aagaagtatt taaactgctg gagtgccctc acctgaatgt gcggaaggca gcccatgagg
2161 ctctgggtca gttttgctgt gcactgcaca aggcctgtca aagctgcccc tcggaaccca
2221 acactgctgc tttgcaggct gccctggccc gagtcgtgcc atcctacatg caggcagtga
2281 acagggagcg ggaacgccag gtggtgatgg ccgtgctgga ggccctgaca ggggtgctcc
2341 gcagctgtgg gaccctcaca ctgaagcccc ctgggcgcct cgctgagctc tgtggcgtgc
2401 tcaaggctgt gctgcagagg aagacagcct gtcaggatac tgacgaggag gaggaagagg
2461 aagatgatga tcaggctgaa tacgacgcca tgttgctgga gcacgctgga gaggccatcc
2521 ctgccctggc agccgcggct gggggagact cctttgcccc attctttgcc ggtttcctgc
2581 cattattggt gtgcaagaca aaacagggct gcacagtggc agagaagtcc tttgcagtgg
2641 ggaccttggc agagactatt cagggcctgg gtgctgcctc agcccagttt gtgtctcggc
2701 tgctccctgt gctgttgagc accgcccaag aggcagaccc cgaggtgcga agcaatgcca
2761 tcttcgggat gggcgtgctg gcagagcatg ggggccaccc tgcccaggaa cacttcccca
2821 agctgctggg gctccttttt cccctcctgg cgcgggagcg acatgatcgt gtccgtgaca
2881 acatctgtgg ggcacttgcc cgcctgttga tggccagtcc caccaggaaa ccagagcccc
2941 aggtgctggc tgccctactg catgccctgc cactgaagga ggacttggag gagtgggtca
3001 ccattgggcg cctcttcagc ttcctgtacc agagcagccc tgaccaggtt atagatgtgg
3061 ctcccgagct tctgcgtatc tgcagcctca ttctggctga caacaagatc ccaccagaca
3121 ccaaggccgc actgttgctg ctcctgacgt tcctggccaa acagcacacc gacagctttc
3181 aagcagctct gggctcactg cctgttgaca aggctcagga gctccaggct gtactgggcc
3241 tctcctagac tgcaggctgc agccagtcca gagagaatag agcctgccca
//