LOCUS AF411044 2645 bp mRNA linear HUM 27-DEC-2001
DEFINITION Homo sapiens DnaJ protein Tid-1 mRNA, complete cds.
ACCESSION AF411044
VERSION AF411044.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2645)
AUTHORS Sarkar,S., Pollack,B.P., Lin,K.T., Kotenko,S.V., Cook,J.R.,
Lewis,A. and Pestka,S.
TITLE hTid-1, a human DnaJ protein, modulates the interferon signaling
pathway
JOURNAL J. Biol. Chem. 276 (52), 49034-49042 (2001)
PUBMED 11679576
REFERENCE 2 (bases 1 to 2645)
AUTHORS Pollack,B.P., Lin,K.-T., Sarkar,S. and Pestka,S.
TITLE Direct Submission
JOURNAL Submitted (15-AUG-2001) Molecular Genetics and Microbiology, Robert
Wood Johnson Medical School - UMDNJ, 675 Hoes Lane, Piscataway, NJ
08854-5635, USA
FEATURES Location/Qualifiers
source 1..2645
/db_xref="H-InvDB:HIT000079221"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="16"
/map="16p13.3"
CDS 45..1406
/function="can bind Janus kinase 2 (Jak2), Hsp70/Hsc70 and
interferon gamma receptor 2 chain (IFN-gammaR2 chain);
overexpression inhibits interferon gamma signaling"
/note="hTid-1; similar to the Drosophila melanogaster
tumor suppressor gene lethal (2) tumorous imaginal discs"
/codon_start=1
/product="DnaJ protein Tid-1"
/protein_id="AAL35323.1"
/translation="MAARCSTRWLLVVVGTPRLPAISGRGARPPREGVVGAWLSRKLS
VPAFASSLTSCGPRALLTLRPGVSLTGTKHYPFICTASFHTSAPLAKEDYYQILGVPR
NASQKEIKKAYYQLAKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDEVKRKQYDAYGSA
GFDPGASGSQHSYWKGGPTVDPEELFRKIFGEFSSSSFGDFQTVFDQPQEYFMELTFN
QAAKGVNKEFTVNIMDTCERCNGKGNEPGTKVQHCHYCGGSGMETINTGPFVMRSTCR
RCGGRGSIIISPCVVCRGAGQAKQKKRVMIPVPAGVEDGQTVRMPVGKREIFITFRVQ
KSPVFRRDGADIHSDLFISIAQALLGGTARAQGLYETINVTIPPGTQTDQKIRMGGKG
IPRINSYGYGDHYIHIKIRVPKRLTSRQQSLILSYAEDETDVEGTVNGVTLTSSGKRS
TGN"
variation 251..267
/replace="tacaggaacaaaacata"
BASE COUNT 654 a 682 c 724 g 585 t
ORIGIN
1 ggccattacc aatcgcgaaa ccggcgcagt gtccccgggc caagatggct gcgcggtgct
61 ccacacgctg gttgctggtg gttgtgggga ccccgcggct gccggctata tcgggtagag
121 gggcccggcc gcccagggag ggcgtggtgg gggcatggct gagccgcaag ctgagcgtcc
181 ccgcctttgc gtcttccctg acctcttgcg gcccccgagc gctgctgaca ttgagacctg
241 gtgtcagcct cacaggaaca aaacattacc ctttcatttg tactgcctcc ttccacacga
301 gtgccccttt ggccaaagaa gattattatc agatattagg agtgcctcga aatgccagcc
361 agaaagagat caagaaagcc tattatcagc ttgccaagaa gtatcaccct gacacaaata
421 aggatgatcc caaagccaag gagaagttct cccagctggc agaagcctat gaggttttga
481 gtgatgaggt gaagaggaag cagtacgatg cctacggctc tgcaggcttc gatcctgggg
541 ccagcggctc ccagcatagc tactggaagg gaggccccac tgtggacccc gaggagctgt
601 tcaggaagat ctttggcgag ttctcatcct cttcatttgg agatttccag accgtgtttg
661 atcagcctca ggaatacttc atggagttga cattcaatca agctgcaaag ggggtcaaca
721 aggagttcac cgtgaacatc atggacacgt gtgagcgctg caacggcaag gggaacgagc
781 ccggcaccaa ggtgcagcat tgccactact gtggcggctc cggcatggaa accatcaaca
841 caggcccttt tgtgatgcgt tccacgtgta ggagatgtgg tggccgcggc tccatcatca
901 tatcgccctg tgtggtctgc aggggagcag gacaagccaa gcagaaaaag cgagtgatga
961 tccctgtgcc tgcaggagtc gaggatggcc agaccgtgag gatgcctgtg ggaaaaaggg
1021 aaattttcat tacgttcagg gtgcagaaaa gccctgtgtt ccggagggac ggcgcagaca
1081 tccactccga cctctttatt tctatagctc aggctcttct tgggggaaca gccagagccc
1141 agggcctgta cgagacgatc aacgtgacga tcccccctgg gactcagaca gaccagaaga
1201 ttcggatggg tgggaaaggc atcccccgga ttaacagcta cggctacgga gaccactaca
1261 tccacatcaa gatacgagtt ccaaagaggc taacgagccg gcagcagagc ctgatcctga
1321 gctacgccga ggacgagaca gatgtggagg ggacggtgaa cggcgtcacc ctcaccagct
1381 ctggaaaaag atccactgga aactaggccg ggaagcagca gcccctccaa gggccagggc
1441 acctgggaga cgggaggatt ccagaacagc agcactgagc tcccacccgc agagcctctg
1501 gacggccttg gcaacagcaa aatcatggga caacacctct ctccacggaa aggtcacagt
1561 ggacagcccg ggcagtagga tgcagcccca gaggctggtg gcagtttcct gtccattggt
1621 aggtgacggc ccctggctca ggcagaggga gatggttaga ctcttgcagg gctaaaactc
1681 taatttggaa ttgaatattg tggatatctt agttaaaggc catgcttaca gcttagaaat
1741 gaagccttaa gctgcatcaa gttacgaagt gattaatttc cttctcagca aacctccggg
1801 aggttccaga atgagttctt cctgacaggt tgtcttcact gggagcgtgg ggcccccagg
1861 ccccaccagc accgtcctcc cctaatgagg ggccctgccg aggcatcagc tgctctgctc
1921 agttagtttt tattcccggg gtaccaagca gctgcacagt cggtgcctgg gaggcacgta
1981 gaggcccaga gagtccctgg gggttctgct ctgaccgtgt gggtggtgat ccttgtcagg
2041 atgtacagtc cttgctccca ccccatccag gatggccgcc tgtccctgac tattgagtcc
2101 tgttgttgta agccaggcat ggagggctcc tgcccttctg ctgagccaca gcccattgca
2161 gcactgtgct ggccagactt cagctgcctt gggaactgaa gccctgccac tgttgctagt
2221 caggggcttg ggttctccca cttacactgt tgacatctat tttctgaagt gtgtttaaat
2281 tattcagtgc taatcattgt tttttccttt gtaaatgttg attcagaaaa ggaaagcaca
2341 ggctaagcag ttgaaggttc cccaccattc agtgagagca gaacccccat tccccagcct
2401 ctgctggtag catgtcgcag tttccatgtg tttcaggatc ttcgggctgt cgttagacag
2461 gttaatgaag aacacttctc aacagtttcc tttttgtttt cctttataat tcactaaaat
2521 aaagcatcta ttagtgtctg atttaggaat gtaaaatgat tctgtattaa tgtaaataag
2581 attatctatt gcaaaaagat atttcaaacc taaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2641 aaaaa
//