LOCUS AF410771 10184 bp DNA linear HUM 27-AUG-2001
DEFINITION Homo sapiens C1q-related factor (CRF) gene, complete cds.
ACCESSION AF410771
VERSION AF410771.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 10184)
AUTHORS Rieder,M.J., Carrington,D.P., Chung,M.-W., Lee,K.L., Poel,C.L.,
Yi,Q. and Nickerson,D.A.
TITLE Direct Submission
JOURNAL Submitted (13-AUG-2001) Molecular Biotechnology, University of
Washington, 1705 NE Pacific, Seattle, WA 98195, USA
COMMENT To cite this work please use: SeattleSNPs. NHLBI Program for
Genomic Applications, UW-FHCRC, Seattle, WA (URL:
http://pga.mbt.washington.edu).
FEATURES Location/Qualifiers
source 1..10184
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
variation 131
/frequency="0.39"
/replace="g"
variation 207
/frequency="0.01"
/replace="t"
misc_feature 1235..2125
/note="Region not scanned for variation"
gene <1682..10054
/gene="CRF"
mRNA join(<1682..2291,9381..10054)
/gene="CRF"
/product="C1q-related factor"
CDS join(1695..2291,9381..9560)
/gene="CRF"
/codon_start=1
/product="C1q-related factor"
/protein_id="AAK95248.1"
/translation="MLLVLVVLIPVLVSSGGPEGHYEMLGTCRMVCDPYPARGPGAGA
RTDGGDALSEQSGAPPPSTLVQGPQGKPGRTGKPGPPGPPGDPGPPGPVGPPGEKGEP
GKPGPPGLPGAGGSGAISTATYTTVPRVAFYAGLKNPHEGYEVLKFDDVVTNLGNNYD
AASGKFTCNIPGTYFFTYHVLMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASN
SVILHLDAGDEVFIKLDGGKAHGGNSNKYSTFSGFIIYSD"
variation 2431
/gene="CRF"
/frequency="0.17"
/replace="t"
variation 2435
/gene="CRF"
/frequency="0.01"
/replace="g"
variation 3729
/gene="CRF"
/frequency="0.01"
/replace="a"
variation 3758
/gene="CRF"
/frequency="0.16"
/replace="g"
variation 3923
/gene="CRF"
/frequency="0.01"
/replace="a"
variation 4101
/gene="CRF"
/frequency="0.03"
/replace="c"
variation 4133
/gene="CRF"
/frequency="0.02"
/replace="t"
variation 4151
/gene="CRF"
/frequency="0.01"
/replace="t"
repeat_region 4296..4431
/gene="CRF"
/rpt_family="AluSx"
/rpt_type=dispersed
repeat_region 4432..4733
/gene="CRF"
/rpt_family="AluY"
/rpt_type=dispersed
variation 4495
/gene="CRF"
/frequency="0.30"
/replace="t"
repeat_region 4734..4914
/gene="CRF"
/rpt_family="AluSx"
/rpt_type=dispersed
variation 4924
/gene="CRF"
/frequency="0.31"
/replace="g"
variation 5097
/gene="CRF"
/frequency="0.03"
/replace="t"
variation 5162
/gene="CRF"
/frequency="0.32"
/replace="g"
variation 5310
/gene="CRF"
/frequency="0.31"
/replace="a"
variation 5347
/gene="CRF"
/frequency="0.06"
/replace="g"
repeat_region 6023..6322
/gene="CRF"
/rpt_family="AluSx"
/rpt_type=dispersed
variation 6079
/gene="CRF"
/frequency="0.02"
/replace="t"
variation 6117
/gene="CRF"
/frequency="0.02"
/replace="c"
variation 6158
/gene="CRF"
/frequency="0.33"
/replace="c"
variation 6339
/gene="CRF"
/frequency="0.03"
/replace="g"
repeat_region 6395..6456
/gene="CRF"
/rpt_family="L2"
/rpt_type=dispersed
variation 6544
/gene="CRF"
/frequency="0.03"
/replace="a"
variation 6558
/gene="CRF"
/frequency="0.37"
/replace="t"
variation 6702
/gene="CRF"
/frequency="0.03"
/replace="t"
variation 6735
/gene="CRF"
/frequency="0.19"
/replace="g"
variation 6761
/gene="CRF"
/frequency="0.01"
/replace="t"
variation 6888
/gene="CRF"
/frequency="0.04"
/replace=""
variation 6960
/gene="CRF"
/frequency="0.01"
/replace="c"
variation 7022
/gene="CRF"
/frequency="0.37"
/replace="t"
variation 7168
/gene="CRF"
/frequency="0.01"
/replace="c"
variation 7398
/gene="CRF"
/frequency="0.32"
/replace="t"
variation 7471
/gene="CRF"
/frequency="0.12"
/replace="g"
variation 7518
/gene="CRF"
/frequency="0.24"
/replace="g"
repeat_region 7838..8143
/gene="CRF"
/rpt_family="AluYb9"
/rpt_type=dispersed
repeat_region 8144..8428
/gene="CRF"
/rpt_family="AluSx"
/rpt_type=dispersed
variation 8169
/gene="CRF"
/frequency="0.04"
/replace="t"
variation 8251
/gene="CRF"
/frequency="0.17"
/replace="t"
variation 8907
/gene="CRF"
/frequency="0.13"
/replace="a"
variation 9199
/gene="CRF"
/frequency="0.06"
/replace="g"
variation 9280..9291
/gene="CRF"
/frequency="0.10"
/replace=""
variation 9925
/gene="CRF"
/frequency="0.36"
/replace="c"
variation 9975
/gene="CRF"
/frequency="0.01"
/replace="c"
variation 10059
/frequency="0.11"
/replace="a"
BASE COUNT 2150 a 2972 c 2959 g 2103 t
ORIGIN
1 gatgtccctg tgtccttcta ctcccagccc tggatgaggt gagcgacctc aaccttgggt
61 agggaaggcc agggaatcat tttgcccatg gtgaagggtc aacagggaga gtgtgagccg
121 gcggggggta cctctcggga gaggagaggc tgggatgtca ttctttagca gccggccagt
181 cgcctccgaa tggctgaatc ctccccggtg ggccggataa aggagggcga aggaggagcg
241 gtggagcagc ccgacctggg cctcagataa tgtgacaaat attttgatgg aagcagacac
301 gtttcggttt atgcaaccta aacactttgc tgcacttgag gaagaggaga gcctcccaca
361 gcctgatggg gagaagagtt agggggcggc ggaggaggct ggggagtgag ggaggaggag
421 ctgaggggct ggatgagatc cacccctcat cctggaggct ggaaaagggg gttacccctc
481 agggacgtat ttgcatctgt cagcatggag aaataacgtg gggtgcccac ctttttagga
541 tccccttttc tccctggtct agaggcagaa gtaaagggat tgagcagagg gagatggaag
601 aaaagggccc aggaaaaagc agcctggcca cagttcggtg aggaaggggc agaggcgagg
661 aggggttgga agctcctgcc ccacctcggg ggagacgggt cccggaacag tcagatccag
721 aaaggaggag gcggctgccg tctggctccg ctgggccccc ggacaggcat tcatccgata
781 tctggatctc ccagacgggt ggtctgcgag gcctgagtgc caaatggtcc cctccgtatc
841 ctcttcttcg cttcataacc ccctttctca tcctaccttc cagctccccg ctccgtcctc
901 ccctcaatcg ctctttgtcc cctgcagacc tgggcgctat cccctcgctt ccgccccctg
961 cgggtcttgg cccgtcgcga ccccagtccc tctgttttcc tggtgaccga ccctcgaagc
1021 ctctcctctc ccgatcccct cggagctctc tagctctccc tgtggccctc tctccctttc
1081 gcattttggt ccctactctc cccttccctt ggagcgcctc tcgggtctct cggaccccgg
1141 cccccacccc atttccgaat ctcggtctcc gcgtactcag tctcttcttt cctctccctg
1201 ctcccgcccg gggtctccgc ggccccgccc ccttatgccc cgcccacctc gaggcgcccg
1261 cggcccaatt aggcgccggc cccgcccgca gccccacccc tagagagccc agagccgcgc
1321 ggagctggcg gggcggggcc cggccgaggg ggcggtggcc cggctcaagg aggcgggagg
1381 agtcaggcgg gaggctgcag gcgggaggcg ggaggcggga ggcggcggcc gcggcgctca
1441 gtccggcagc gcagcaggag ggaggcgcga ggcaggagcc ggcggctggg ctccgcagcg
1501 cagccagcgc agcgcggcgc cccgggcccg gccccatgcc cgcagccccg ccggaccgtc
1561 cttgagcgcg ggcgcctagc ccgcgccccc tgcccgccgg caccattgcc ccgacggcgc
1621 ggccgggcgg cccggcgctc cccaggctcc gcgcgggccg aaagacgctg ctagcggccg
1681 ccgcgggtgt ggtgatgctg ctggtgctgg tggtgctcat ccccgtgctg gtgagctcgg
1741 gcggcccgga aggccactat gagatgctgg gcacctgccg catggtgtgc gacccctacc
1801 ccgcgcgggg ccccggcgcc ggcgcgcgga ccgacggcgg cgacgccctg agcgagcaga
1861 gcggcgcgcc cccgccttcc acgctggtgc agggccccca ggggaagccg ggccgcaccg
1921 gcaagcccgg ccctccgggg cctcccgggg acccaggtcc tcccggccct gtggggccgc
1981 cgggggagaa gggtgagcca ggcaagccgg gccctccggg gctgccgggc gcggggggca
2041 gcggcgccat cagcactgcc acctacacca cggtgccgcg cgtggccttc tacgccggcc
2101 tcaagaaccc ccacgagggt tacgaggtac tcaagtttga cgacgtggtc accaacctag
2161 gcaacaacta cgacgcggcc agcggcaagt ttacgtgcaa cattcccggc acctactttt
2221 tcacctacca tgtcctcatg cgcggcggcg acggcaccag tatgtgggca gacctctgca
2281 agaatggcca ggtgggccag gcgggggcat ggggctgggc tgggcccagg gcacccaggg
2341 agcccggggc aaatgggtac ctgatcggag ttggcggggg cgccaggcgg acgcaggtgg
2401 agatcccacc ccacagcggc cccgcttggt catcacgtgt ggggatggtc ggagccagcg
2461 gacatcgccg atcctcagtt cctgggttcc cgctccaaga cagacgctgc tgggcaccgt
2521 ctggaacgct actggaaatg cgggaaatga acccaactag tcagagcgca gggctcccag
2581 gtgcacggac ttgcccttgg gggcttgccc cttgggaagt ggattcgggc cgacagcagt
2641 gggcgataag gggagggcaa ggatgggctc tggcgtatgg aacagggaga agcagcatcc
2701 gcgcccgcgg gcgcctaggc gcgtggccat gggcgcgagc ggagaaggct ggctgcagga
2761 aatgtttggg gcacaaaggc aaagggagcc cggtgcttac agccctggct gcagtgcctc
2821 ccctgccctg gagaagggac cattgggcga atctgacacc ctttgcaaaa tccgggagtt
2881 ggggagctgt ttcccactgt agcagagctt ccccaaaaag aaggcagtct ggggggcggg
2941 ggagtttttc ctcctgaggc ggggaggggg tggggggtgg ggggtggtgg aagagatgga
3001 aactccccct cctcttggtc tcccagctcc agcccctcct gactctggag tgtgtggggt
3061 cctctccatt ctccgtcccc atctcagacg ctgcagctgg aaagcactga gtgtgtcggg
3121 gactctggta ccgggactcg catgtgcgtg tagctctcct tggaatggcc gaccccagga
3181 ccagcctcca cccagccccg ccctggggtg acaattttag ccagctctct tgataccacc
3241 tcccttccca gtgctctcac tcgtggtggc ctgtgacctg ggggtgtggt caggctgagc
3301 attctcttcg aagaagggga ccactggtca gaactaaagc tgagctagtg gaagttgaga
3361 aggaatctct cacgattaag atacaagacc ttgttggaac ccttcccaca gcagcactgc
3421 cctgaggctc tgccagcctg cgggtctgca agtcttaggg gcagagacag gggcaggcag
3481 ggaaagtgag cagatagcct gccaggtgct tataagtcag cccttcttct ctttcctctg
3541 cctggctgct gccccgccaa caccttttct ctggtttctg cctctcccct gcctctttct
3601 tctattttgc tgtttcttgt ccatctctct cctgtgtctg ccttttccat ctctccctgg
3661 gtttctggcc tctcctcccc ggatctaacc ccactcttct ctattccttg tatgtctctc
3721 tttcccacgt gtgtctatca gacatccccg tgtctctcct ctttgtcctt ggttcctgac
3781 caaatgggag gccccagtat ccagcaaagg ctcattctgc agacagcccc atgattcccc
3841 ctattaatca ccaataaggg atgcagcaat gtcaccttca tcaatggaat gtcttccttt
3901 cccaaagaag tttgggctga cacagagctg aggtttcagg ggattggcag cttgcctgga
3961 tagggaggca gtcattgggc cacaggttgg ccctagaccc tgcaccacct caggaagtcc
4021 cagcaggtcc ccagagatga ggcaacaaga ggccccggag atgctatgtg cttagaatgg
4081 ggaacttgct tcagtcactg ggaggtaaaa ccatctcaaa agctcctttt ccctccagca
4141 ggggcagggt gttgacagag tctgatgaag gggtgctcac tggagatggg accacaggct
4201 agtaggaaaa aaggaggtgg ctttaactag gggtttcaaa ggcccagcac tttaatagtt
4261 attcagacca gccccctcaa aagaaaaaca ggagaggctg ggcctggtgg ctcacgtctg
4321 taatcccagc actttgggag gctgaggcag atggatcaac tgaggtcagg ggtttgagat
4381 catcctggcc aacacagcga aacaccatct ctattaaaaa tacaaacatt aggccaggca
4441 cggtggctca cgcctgtaat cccagcactt tgggaggccg aggcaagtgg atcacgaggt
4501 caggagatca agaccatcct ggctaacacg gtgaaacccc atctctacta aaaatacaaa
4561 aaattagctg ggcgtggtgg caggcacctg tagtcccagc tacttgggag gctaaggcgg
4621 gagaatggcg tgaacccggg aggcggagct tgcagtgagc tgagatcgcg ccactgcact
4681 acagcctggg tgacagagcg agactccgtc tcaaaaaaaa aaaaaaatac aaacattagc
4741 tgggcgtgat ggtgcatacc tgtaatccca gttagtcagg aggctgaggc aagagaataa
4801 cttgaaccca ggaggcagag gttgcaatga ggtgagatct cgccactgta ctctagcctg
4861 ggcaacagag tgagactctg tctcaaaaaa aaaagaaaag aaaagaaaag aaaagataaa
4921 aacaaaaaga aaagaaaacc aggagaaata gtggggcccg tagccccctc tcccatgtcc
4981 tttatgactt cttccaaatt gcccaagaga ctcatttgat ctcactagcc atcccacttg
5041 ttagttttga gcccctacta ggagccagat ttgaggcttt gtaggagttc agtccacttg
5101 ccctccaaga cctcatggcc tatgcagggg gaacattcat aacatacaac cacacgcccc
5161 aacgaatact gtgttaaagg tgggctggga gcccagctga tgactttggt ccccaaatgt
5221 gttggctggg agggagtgct tcagtagggc ctaccctggt gcagaccaac ctgatgcagg
5281 gggagaagat ggtgaacctt ggtctgcaag gtgaggagat accacaaggg agaatataaa
5341 aggtcaagtg taggggaaag ccagctcaga ggtggacaag gacatttaaa taagcagaga
5401 aaaaaatggc aggaccagac aatgtatggg aacaaaagag agaagcttgt atctcttgtg
5461 acttcagaac caggggccac cctgagcact gcgcttttcc ttcctggctt cctgcctgta
5521 gagaggcttc cagaatttct ttagggaggc agagctgaat ctgggctctg cctcctctcc
5581 gggcaagttc gggatgggga gcaccacctt catgcctggc actgaggctc cctctgtcct
5641 tatctgaggc ccactggccc cagtccttag gggtagcctt gcatcagcac ccctgatggc
5701 accaagtcct ggccattagg atgcaaggag cctggggaaa ggactctggg ttggcagtgg
5761 ggccctgggt gtggtgagtt gcctgcagct gcctccaaga tccacagttc aggtgggttg
5821 gagaggacac aaaattaata aactgggcag ggggctttgt gaggatgtgc cagggcctgt
5881 ggtcagggtg ctgcttatcc agggtaggag gctgtgggga ggtgagtatc accaatgggc
5941 caggggtttg acaacagaat ctgagtgtgg cgagaggtgc tggcatatat aaattgaagg
6001 tggtggtata aagacctaag aaggctgtgc acagtggctc acgcctgtaa tcccagcact
6061 ttgggaggct gaggcgggcg gatcaccaga ggtcaggagt tcgagaccag cctgtctaac
6121 atggtgaaac cctgtctcta ctaaaaatac aaaaaaatat agccgggtgt ggtggtgggt
6181 gcctgtaatt ccagttactc gggaggctga ggtaggagaa tcacttgaac ctgggaagtg
6241 gaagttgcag tgagccaaga tcgcaccact gcactccatc ctgggtgaca gagcaagact
6301 ctgtctcaaa aaagaaaaaa gacctaagga gatcagcctc tcccctggtg gtggcagatg
6361 gccccctggc tatcctttct ggcccctaat acctttcaca acacagagca cagtgcctgg
6421 cacagtggga atgcagttaa tgtatgtatg aaaatgcaag tgtcccccat gggccaggct
6481 ggctccccta tgggagccac atctgtacac ccaagacccc agcattgatc tgagggcagg
6541 aacgtgtttc ctggatgccc tctcacccag ttcccttggt cagaccattg cctcagtttc
6601 ccctcctggc agcccttgag gagctgatta tacagcgctc cctcataaca aggcccaaac
6661 ctgctttcct gcttccttgg caacctcatt tccccacact tccccttgga ccccaggagg
6721 agctgcaggc ctcaactgtc tccagtcagg cagagaattg ggacccctgg gttccattct
6781 tggatccccc accatctaag gatggaaggg cataaattct ctctgcctcc atggataatt
6841 aggataatta cggcaacaat catggtgatg aataaataat aaacataagc ataacagttc
6901 tgatgcagtc acatcaccag gagattcctg atgacagatg actctgttcc aatggatttg
6961 gctattaagg agcacactgt tttaatgagt taaggctaaa ttaatctggg caataaaaat
7021 aattgttatt agtagtaatt tattagcaaa gataatgaaa tgcatgtgta ataataaata
7081 ttaccaggat tagggctcag ggaacaatac agaagttggc tgtttgcttt cagctcttcc
7141 ctaataactc aaagccccat caagatctaa tgtttttttt tctttatcat caaaagactt
7201 ttacagaggt ggcagtggtg aggcaaagtc ttctcatcca ttttctagac agagaaactg
7261 agctccttgg cagacagcat ctcccccttc atttattccc tcccaccttt aactagacca
7321 gttttcccag ctaagcacac aaagagtttc ttctcaggtt gggaagaaga ggttgaggga
7381 aaagaagggg ctggagaagg gctttaaagg gaggccctca tgcaaatatg tcgggtcctc
7441 ttcattgcag catcgcggct gagtcagcag ctctggcaca gctgacctgc agtgctgcct
7501 ccagcccagg agagaggatg ggcccctccc ctaatttggc ttggttctac ccagacttca
7561 gccctgggag ttgggatggt aagctgcctt cagtgaaggg acaggataga gaggggccgt
7621 ggagaaacct ggctgagaga actccactca gtgcagcctc cccacaccac aagccacagt
7681 cctggagagg gcgcttctct tccatgtctc tacccaggat accctggaga ggccccgatc
7741 ctcaaactca ggacttatgt ttccatacct gttagctgaa tgtctgtaga tcattcgttc
7801 accaccacac aatctctctc tctctctctc tctctctttt tttttttttt tttttgagac
7861 ggagtctcgc tctgtcgccc aggccggact gcggactgca gtggcgcaat ctcggctcac
7921 tgcaagctcc gcttcccggg ttcacgccat tctcctgcct cagcctcccc agtagctggg
7981 actacaggcg cccgccaccg cgcccggcta attttttgta tttttagtag agacggggtt
8041 tcaccttgtt agccaggatg gtctcgatct cctgacctca tgatccaccc gcctcggcct
8101 cccaaagtgc tgggattaca ggcgtgagcc accgcgcctg gccttttttt ttttttgaga
8161 ctgagtctca ctatgtcgcc caggctggag cgcagtggca tgatctcggc tcactgcagc
8221 ctccatttcc caggttcaag tgattctcct gcctcagcct ccccaggagc tgggattaca
8281 ggcgtgccac tatgcctagc taatttttgt atttttagta gagatggggg tctcaccata
8341 ttggccaggc tgttctcgaa ctcctgacct caaatgatcc acctgcctgg gcctcccaaa
8401 gtgctgggat cacaggcatg agccaccgta tgcagccacc acacaatctc ttatgattat
8461 agtcagagcc cccaaaagtg acggcaggct ccaagcccaa atgctggtgc tcccttgacc
8521 cattatcctg cctgtccctc cccatccccc atcaaggcag ggaccagcaa ggatgtcaca
8581 tcagactgag aatcccagag ggaagtaagg cctggattcc cttcttccca cccagttcct
8641 ttctaccacc ctgaggtgag acaggaggag ctacaatcct ctttgggtgg gtagtgacag
8701 gtacatagct acagctccat ggaggctggc acccaggccc cttctaaact ctgggagggg
8761 aaagcattac caggccttct gtctcactgc tgcagcagga gagactctgg aatgcacttc
8821 agaccaaaga cctggccctg gttccagggt ggttgctgac tggcagcctg gcattggtcc
8881 agctgcctga cctgtggggc caaggtgtgc ccttgtgtcc atccactgac ataagatcca
8941 gcgggtgtgg ctgaaacgat ggcatcatta tgaaagcaga gaggaaggaa tgatgagagt
9001 agggaaggcc ctccattccc tggaggtcca gagaattcct ctttgcaagg acaggcttcc
9061 aggcttcctg gaggtattga ggttctcagc cagctggagg gaaagcccta taagagttaa
9121 ggaggaagac tctgccttga ctcccaattc aggcccagat cagacctgcc ctagaaatcc
9181 agggatcctc tctgcccctt tcctgaaaca agtcctgtat gattggaagg gggcggggga
9241 gggggagcgt ggcagggatg aggcgaggct ggaggccagg tttctgggtc tgctgatcct
9301 cccccacggg actgcctcac ctccctccct tctcatcctc tctctcctct cgccctccct
9361 cccgtgtccc ccacccgcag gtgcgggcca gtgctattgc ccaggacgcg gaccagaact
9421 acgactacgc cagcaacagc gtgatcctgc acctggacgc cggcgacgag gtcttcatca
9481 agctggatgg aggcaaagca cacggcggca acagcaacaa atacagcacg ttctctggct
9541 tcatcatcta ctccgactga gctccccacg tctccctcca cccacgtccc tcacccgccg
9601 gggtcccctc cgggcggggc agacgatgac tcgcccctcg cccacccgct cgctgcccgg
9661 ccctccccgg ctatgacgcc cccggcccgt gctcaacacc gcctgggcca cagctaggcc
9721 ctcccaccgg ctcgctgcag agccgggccc agcgcgccct gtccccgtgc cagggaaccg
9781 gggttgaccg cccccgccca gcccgcgcta tatatttgta caataggact gtttactgcc
9841 cacctccgcc tgccagccca ccccagcctg gggagaggtc gcggcggcgg gtttgcttcc
9901 tgcgctctga gatgagctgc cctcggctcc ctccggggtg gcgcgcccgg gggagggggg
9961 agttgggggc tggatagctt cccagcaccc tcagagcccc cgcccggctg tgccccgtct
10021 gaccaaagtt ataataaaaa cattttcacc ccgcaggggt ttcagtctgt gccctgggga
10081 gggctgcggg aggcgacggt ggaccgtgcc ctcctccaga ttaggaaggg gtctggtgga
10141 agtttctagg ggaaaccagg tgccagagcc agagctactc caag
//