LOCUS AF410459 5883 bp mRNA linear HUM 02-MAR-2002
DEFINITION Homo sapiens CD109 (CD109) mRNA, complete cds.
ACCESSION AF410459
VERSION AF410459.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5883)
AUTHORS Lin,M., Sutherland,D.R., Horsfall,W., Totty,N., Yeo,E., Nayar,R.,
Wu,X.F. and Schuh,A.C.
TITLE Cell surface antigen CD109 is a novel member of the alpha(2)
macroglobulin/C3, C4, C5 family of thioester-containing proteins
JOURNAL Blood 99 (5), 1683-1691 (2002)
PUBMED 11861284
REFERENCE 2 (bases 1 to 5883)
AUTHORS Lin,M., Sutherland,D.R., Horsfall,W., Totty,N., Yeo,E., Nayar,R.,
Wu,X.-F. and Schuh,A.C.
TITLE Direct Submission
JOURNAL Submitted (14-AUG-2001) Medicine, University of Toronto, 1 King's
College Circle, Room 7366, Toronto, Ontario M5S 1A8, Canada
FEATURES Location/Qualifiers
source 1..5883
/db_xref="H-InvDB:HIT000079211"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="K1"
gene 1..5883
/gene="CD109"
5'UTR 1..112
/gene="CD109"
CDS 113..4450
/gene="CD109"
/note="associated with the Gov alloantigen system"
/codon_start=1
/product="CD109"
/protein_id="AAL84159.1"
/translation="MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTI
GVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEIY
ELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPY
KTSLNILIKDPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQS
FQVSEYVLPKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGK
KKNITKTFKINGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGI
SRNVSTNVFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVIT
VTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGS
KSSMAVHSLFKSPSKTYIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQLVA
VGKQNSTMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKV
KAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLG
MFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSLGS
SPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPV
ELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNE
INATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPTASDAVTQMILVKAEGI
EKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASL
IRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDG
SFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDP
GRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFSRGISDNYT
LALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSLDIEVAA
YALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTN
IQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPMAVNISANGFGFAICQLNVVYN
VKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALMEVNL
LSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDAS
VSIVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHHSSVIFIFCFK
LLYFMELWL"
3'UTR 4451..5883
/gene="CD109"
misc_feature 4748
/gene="CD109"
/note="alternative polyA site found on clone K1"
BASE COUNT 1697 a 1173 c 1241 g 1772 t
ORIGIN
1 ctaaactcga attaagaggg aaaaaaaatc agggaggagg tggcaagcca caccccacgg
61 tgcccgcgaa cttccccggc agcggactgt agcccaggca gacgccgtcg agatgcaggg
121 cccaccgctc ctgaccgccg cccacctcct ctgcgtgtgc accgccgcgc tggccgtggc
181 tcccgggcct cggtttctgg tgacagcccc agggatcatc aggcccggag gaaatgtgac
241 tattggggtg gagcttctgg aacactgccc ttcacaggtg actgtgaagg cggagctgct
301 caagacagca tcaaacctca ctgtctctgt cctggaagca gaaggagtct ttgaaaaagg
361 ctcttttaag acacttactc ttccatcact acctctgaac agtgcagatg agatttatga
421 gctacgtgta accggacgta cccaggatga gattttattc tctaatagta cccgcttatc
481 atttgagacc aagagaatat ctgtcttcat tcaaacagac aaggccttat acaagccaaa
541 gcaagaagtg aagtttcgca ttgttacact cttctcagat tttaagcctt acaaaacctc
601 tttaaacatt ctcattaagg accccaaatc aaatttgatc caacagtggt tgtcacaaca
661 aagtgatctt ggagtcattt ccaaaacttt tcagctatct tcccatccaa tacttggtga
721 ctggtctatt caagttcaag tgaatgacca gacatattat caatcatttc aggtttcaga
781 atatgtatta ccaaaatttg aagtgacttt gcagacacca ttatattgtt ctatgaattc
841 taagcattta aatggtacca tcacggcaaa gtatacatat gggaagccag tgaaaggaga
901 cgtaacgctt acatttttac ctttatcctt ttggggaaag aagaaaaata ttacaaaaac
961 atttaagata aatggatctg caaacttctc ttttaatgat gaagagatga aaaatgtaat
1021 ggattcttca aatggacttt ctgaatacct ggatctatct tcccctggac cagtagaaat
1081 tttaaccaca gtgacagaat cagttacagg tatttcaaga aatgtaagca ctaatgtgtt
1141 cttcaagcaa catgattaca tcattgagtt ttttgattat actactgtct tgaagccatc
1201 tctcaacttc acagccactg tgaaggtaac tcgtgctgat ggcaaccaac tgactcttga
1261 agaaagaaga aataatgtag tcataacagt gacacagaga aactatactg agtactggag
1321 cggatctaac agtggaaatc agaaaatgga agctgttcag aaaataaatt atactgtccc
1381 ccaaagtgga acttttaaga ttgaattccc aatcctggag gattccagtg agctacagtt
1441 gaaggcctat ttccttggta gtaaaagtag catggcagtt catagtctgt ttaagtctcc
1501 tagtaagaca tacatccaac taaaaacaag agatgaaaat ataaaggtgg gatcgccttt
1561 tgagttggtg gttagtggca acaaacgatt gaaggagtta agctatatgg tagtatccag
1621 gggacagttg gtggctgtag gaaaacaaaa ttcaacaatg ttctctttaa caccagaaaa
1681 ttcttggact ccaaaagcct gtgtaattgt gtattatatt gaagatgatg gggaaattat
1741 aagtgatgtt ctaaaaattc ctgttcagct tgtttttaaa aataagataa agctatattg
1801 gagtaaagtg aaagctgaac catctgagaa agtctctctt aggatctctg tgacacagcc
1861 tgactccata gttgggattg tagctgttga caaaagtgtg aatctgatga atgcctctaa
1921 tgatattaca atggaaaatg tggtccatga gttggaactt tataacacag gatattattt
1981 aggcatgttc atgaattctt ttgcagtctt tcaggaatgt ggactctggg tattgacaga
2041 tgcaaacctc acgaaggatt atattgatgg tgtttatgac aatgcagaat atgctgagag
2101 gtttatggag gaaaatgaag gacatattgt agatattcat gacttttctt tgggtagcag
2161 tccacatgtc cgaaagcatt ttccagagac ttggatttgg ctagacacca acatgggtta
2221 caggatttac caagaatttg aagtaactgt acctgattct atcacttctt gggtggctac
2281 tggttttgtg atctctgagg acctgggtct tggactaaca actactccag tggagctcca
2341 agccttccaa ccatttttca tttttttgaa tcttccctac tctgttatca gaggtgaaga
2401 atttgctttg gaaataacta tattcaatta tttgaaagat gccactgagg ttaaggtaat
2461 cattgagaaa agtgacaaat ttgatattct aatgacttca aatgaaataa atgccacagg
2521 ccaccagcag acccttctgg ttcccagtga ggatggggca actgttcttt ttcccatcag
2581 gccaacacat ctgggagaaa ttcctatcac agtcacagct ctttcaccca ctgcttctga
2641 tgctgtcacc cagatgattt tagtaaaggc tgaaggaata gaaaaatcat attcacaatc
2701 catcttatta gacttgactg acaataggct acagagtacc ctgaaaactt tgagtttctc
2761 atttcctcct aatacagtga ctggcagtga aagagttcag atcactgcaa ttggagatgt
2821 tcttggtcct tccatcaatg gcttagcctc attgattcgg atgccttatg gctgtggtga
2881 acagaacatg ataaattttg ctccaaatat ttacattttg gattatctga ctaaaaagaa
2941 acaactgaca gataatttga aagaaaaagc tctttcattt atgaggcaag gttaccagag
3001 agaacttctc tatcagaggg aagatggctc tttcagtgct tttgggaatt atgacccttc
3061 tgggagcact tggttgtcag cttttgtttt aagatgtttc cttgaagccg atccttacat
3121 agatattgat cagaatgtgt tacacagaac atacacttgg cttaaaggac atcagaaatc
3181 caacggtgaa ttttgggatc caggaagagt gattcatagt gagcttcaag gtggcaataa
3241 aagtccagta acacttacag cctatattgt aacttctctc ctgggatata gaaagtatca
3301 gcctaacatt gatgtgcaag agtctatcca ttttttggag tctgaattca gtagaggaat
3361 ttcagacaat tatactctag cccttataac ttatgcattg tcatcagtgg ggagtcctaa
3421 agcgaaggaa gctttgaata tgctgacttg gagagcagaa caagaaggtg gcatgcaatt
3481 ctgggtgtca tcagagtcca aactttctga ctcctggcag ccacgctccc tggatattga
3541 agttgcagcc tatgcactgc tctcacactt cttacaattt cagacttctg agggaatccc
3601 aattatgagg tggctaagca ggcaaagaaa tagcttgggt ggttttgcat ctactcagga
3661 taccactgtg gctttaaagg ctctgtctga atttgcagcc ctaatgaata cagaaaggac
3721 aaatatccaa gtgaccgtga cggggcctag ctcaccaagt cctgtaaagt ttctgattga
3781 cacacacaac cgcttactcc ttcagacagc agagcttgct gtggtacagc caatggcagt
3841 taatatttcc gcaaatggtt ttggatttgc tatttgtcag ctcaatgttg tatataatgt
3901 gaaggcttct gggtcttcta gaagacgaag atctatccaa aatcaagaag cctttgattt
3961 agatgttgct gtaaaagaaa ataaagatga tctcaatcat gtggatttga atgtgtgtac
4021 aagcttttcg ggcccgggta ggagtggcat ggctcttatg gaagttaacc tattaagtgg
4081 ctttatggtg ccttcagaag caatttctct gagcgagaca gtgaagaaag tggaatatga
4141 tcatggaaaa ctcaacctct atttagattc tgtaaatgaa acccagtttt gtgttaatat
4201 tcctgctgtg agaaacttta aagtttcaaa tacccaagat gcttcagtgt ccatagtgga
4261 ttactatgag ccaaggagac aggcggtgag aagttacaac tctgaagtga agctgtcctc
4321 ctgtgacctt tgcagtgatg tccagggctg ccgtccttgt gaggatggag cttcaggctc
4381 ccatcatcac tcttcagtca tttttatttt ctgtttcaag cttctgtact ttatggaact
4441 ttggctgtga tttattttta aaggactctg tgtaacacta acatttccag tagtcacatg
4501 tgattgtttt gttttcgtag aagaatactg cttctatttt gaaaaaagag ttttttttct
4561 ttctatgggg ttgcagggat ggtgtacaac aggtcctagc atgtatagct gcatagattt
4621 cttcacctga tctttgtgtg gaagatcaga atgaatgcag ttgtgtgtct atattttccc
4681 ctcacaaaat cttttagaat ttttttggag gtgtttgttt tctccagaat aaaggtatta
4741 ctttagaaat aggtattctc ctcattttgt gaaagaaatg aacctagatt cttaagcatt
4801 attacacatc catgtttgct taaagatgga tttccctggg aatgggagaa aacagccagc
4861 aggaggagct tcatctgttc ccttcccacc tccaacctag ccctactgcc caccccaccc
4921 caacccaccc catgcccagt ggtctcagta gatacttctt aactggaaat tctttctttt
4981 cagaatctag gtggtgaatt ttttttaagt ggcacggtct ttttctgctt gaaatctgat
5041 cacacccccc agccattgcc ctccctctct ttttcctctg tagagaaatg tgaggggcag
5101 tacatttact gtgcttttca caccatctca gaggttgagg agcatactga aaattgccct
5161 ggggggtgct gggtgtgctg tctccttccc acatcctcag ccccacacca gctctatttc
5221 aggggtgaga gtcagagagc actgcaatat gtgcttcatg ggatttcgat tcgaagatcc
5281 tagaccaggg agacactgtg agccagggat acaacaaaat actaggtaag tcactgcaga
5341 ccgacctccc tgcagtttgg gaaagaagct gggtttgtgg agaatcagag catcttgaca
5401 tgactgctga cctaaagatc cctggcattg gccagggatc ctgtggaacc tcttctagtt
5461 caggggtgtg agcattagac tgccagttgt ctagtgacat ctgatgcttg ctgtgaactt
5521 ttaagatccc cgaatcctga gcacctcaat ctttaattgc cctgtattcc gaagggtaat
5581 ataatttatc tggatggaaa ttttaaagat gaatccccct tttttctttt cttctctctt
5641 ttctttcctt ctccctttct tctttgcctt ctaaatatac tgaaatgatt tagatatgtg
5701 tcaacaatta atgatctttt attcaatcta agaaatggtt tagtttttct ctttagctct
5761 atggcatttc actcaagtgg acaggggaaa aagtaattgc catgggctcc aaagaatttg
5821 ctttatgttt ttagctattt aaaaataaat ccatcaaaaa taaagtatgc aaatgtatct
5881 ttt
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