LOCUS AF407333 2343 bp mRNA linear HUM 12-OCT-2001
DEFINITION Homo sapiens sperm ion channel mRNA, complete cds.
ACCESSION AF407333
VERSION AF407333.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2343)
AUTHORS Ren,D., Navarro,B., Perez,G., Jackson,A.C., Hsu,S., Shi,Q.,
Tilly,J.L. and Clapham,D.E.
TITLE A sperm ion channel required for sperm motility and male fertility
JOURNAL Nature 413 (6856), 603-609 (2001)
PUBMED 11595941
REFERENCE 2 (bases 1 to 2343)
AUTHORS Ren,D. and Clapham,D.E.
TITLE Direct Submission
JOURNAL Submitted (08-AUG-2001) Cardiology, Children's Hospital, 320
Longwood Ave, Boston, MA 02115, USA
FEATURES Location/Qualifiers
source 1..2343
/db_xref="H-InvDB:HIT000079169"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="sperm"
CDS 1..2343
/note="CatSper"
/codon_start=1
/product="sperm ion channel"
/protein_id="AAL14105.1"
/translation="MDQNSVPEKAQNEADTNNADRFFRSHSSPPHHRPGHSRALHHYE
LHHHGVPHQRGESHHPPEFQDFHDQALSSHVHQSHHHSEARNHGRAHGPTGFGLAPSQ
GAVPSHRSYGEDYHDELQRDGRRHHDGSQYGGFHQQSDSHYHRGSHHGRPQYLGENLS
HYSSGVPHHGEASHHGGSYLPHGPNPYSESFHHSEASHLSGLQHDESQHHQVPHRGWP
HHHQVHHHGRSRHHEAHQHGKSPHHGETISPHSSVGSYQRGISDYHSEYHQGDHHPSE
YHHGDHPHHTQHHYHQTHRHRDYHQHQDHHGAYHSSYLHGDYVQSTSQLSIPHTSRSL
IHDAPGPAASRTGVFPYHVAHPRGSAHSMTRSSSTIRSRVTQMSKKVHTQDISTKHSE
DWGKEEGQFQKRKTGRLQRTRKKGHSTNLFQWLWEKLTFLIQGFREMIRNLTQSLAFE
TFIFFVVCLNTVMLVAQTFAEVEIRGEWYFMALDSIFFCIYVVEALLKIIALGLSYFF
DFWNNLDFFIMAMAVLDFLLMQTHSFAIYHQSLFRILKVFKSLRALRAIRVLRRLSFL
TSVQEVTGTLGQSLPSIAAILILMFTCLFLFSAVLRALFRKSDPKRFQNIFTTIFTLF
TLLTLDDWSLIYMDSRAQGAWYIIPILIIYIIIQYFIFLNLVITVLVDSFQTALFKGL
EKAKQERAARIQEKLLEDSLTELRAAEPKEVASEGTMLKRLIEKKFGTMTEKQQELLF
HYLQLVASVEQEQQKFRSQAAVIDEIVDTTFEAGEEDFRN"
BASE COUNT 541 a 792 c 533 g 477 t
ORIGIN
1 atggatcaaa actcagtgcc tgaaaaggct cagaatgagg cagacaccaa taacgcagat
61 aggttctttc gctctcactc atcaccccca caccacaggc caggccacag cagagctctc
121 caccattacg agttgcacca tcacggcgtg ccccaccaac gtggtgaatc tcaccaccct
181 ccggagttcc aagacttcca cgaccaagcc ttgtcctccc atgtccacca atctcaccac
241 cacagcgagg cacggaatca cggcagagcc catggcccca caggctttgg tctggctccc
301 tctcaaggcg ccgtcccctc ccaccgttcc tacggtgagg actaccatga tgagctccaa
361 cgtgatggca ggaggcatca tgatgggtcc caatacggtg ggttccatca gcagagtgac
421 tcccattacc atagggggtc tcaccatggc agaccccaat atctcggtga gaatttatcc
481 cactattcct ctggcgtgcc ccaccacggt gaggcttccc accatggtgg gtcctacctc
541 ccccatggac ccaatcccta cagtgagtcc ttccaccaca gcgaggcttc ccaccttagc
601 gggctccaac acgatgagtc ccagcatcac caagtccccc accgtggctg gccccaccat
661 caccaagtcc accaccatgg caggtcccgt catcatgaag cccaccagca tggaaagtct
721 cctcatcacg gagagaccat ttcccctcat tcctctgtgg ggtcctacca gcgtgggata
781 tctgactatc acagcgagta ccaccaaggt gatcaccacc ccagtgagta ccaccatggc
841 gaccatcccc accacacaca gcaccactac caccagaccc accggcaccg agactaccat
901 cagcaccaag accaccacgg cgcgtatcat tccagttacc tccatggcga ctacgtccag
961 agcacttccc aactctctat cccacacaca tcccggagcc tgattcacga tgcccccggc
1021 cctgctgctt ctcgtacagg agtcttcccc tatcacgtag cacacccacg gggctcggct
1081 cacagcatga ctcggtcctc cagcacaatc cgctcacgtg tcacccagat gtccaaaaaa
1141 gtccataccc aggatatctc caccaaacat tcagaagact ggggcaaaga agaagggcaa
1201 tttcagaaac gcaaaaccgg caggctccag cggacccgca agaagggaca ctctaccaat
1261 ctcttccagt ggctgtggga aaagctaacc ttcctcattc agggcttccg ggaaatgatc
1321 cggaacctga cccaatcctt ggcctttgaa actttcatct tcttcgttgt ctgcctcaac
1381 accgtcatgc tggtggccca gaccttcgct gaagtcgaga tccggggcga gtggtacttc
1441 atggccttgg actccatatt cttctgcatc tacgtggtgg aagccctgct caagatcatc
1501 gccctgggcc tctcgtactt ctttgacttc tggaacaatt tggacttctt cattatggcc
1561 atggccgtgc tggacttctt gctgatgcag acccactcct tcgccatcta ccaccaaagc
1621 ctcttccgga tcctcaaggt cttcaagagc ctgcgggccc tgagggcaat ccgggtcctg
1681 cggaggctca gcttcctgac cagcgtccag gaagtgacag ggaccctggg ccagtccttg
1741 ccgtccatcg cagccatcct catcctcatg tttacctgcc tcttcctctt ctccgcggtc
1801 ctccgggcac tgttccgcaa atctgacccc aagcgcttcc agaacatctt caccaccatc
1861 ttcaccctct tcaccttgct cacgctggat gactggtccc tcatctacat ggacagccgt
1921 gcccagggcg cctggtacat cattcccatc ctcataattt acatcatcat ccagtacttc
1981 atcttcctca acctggtgat tactgtcctg gtggatagct tccagacggc gctgttcaaa
2041 ggccttgaga aagcgaagca ggagagggcc gcccggatcc aagagaagct gctggaagac
2101 tcactgacgg agctcagagc tgcagagccc aaagaggtgg cgagtgaagg caccatgctg
2161 aagcggctca tcgagaaaaa gtttgggacc atgactgaga agcagcagga gctcctgttc
2221 cattacctgc agctggtggc aagcgtggag caggagcagc agaagttccg ctcccaggca
2281 gccgtcatcg atgagattgt ggacaccaca tttgaggctg gagaagagga cttcaggaat
2341 tga
//