LOCUS AF406780 6352 bp mRNA linear HUM 17-MAY-2004
DEFINITION Homo sapiens alpha 1 type XXII collagen mRNA, complete cds.
ACCESSION AF406780
VERSION AF406780.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6352)
AUTHORS Koch,M., Schulze,J., Hansen,U., Ashwodt,T., Keene,D.R.,
Brunken,W.J., Burgeson,R.E., Bruckner,P. and Bruckner-Tuderman,L.
TITLE A novel marker of tissue junctions, collagen XXII
JOURNAL J. Biol. Chem. 279 (21), 22514-22521 (2004)
PUBMED 15016833
REFERENCE 2 (bases 1 to 6352)
AUTHORS Koch,M., Jin,W., Ashworth,T. and Burgeson,R.E.
TITLE Alpha 1 (XXII) Collagen, a New Member of the Collagen Subfamily
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 6352)
AUTHORS Koch,M., Jin,W., Ashworth,T. and Burgeson,R.E.
TITLE Direct Submission
JOURNAL Submitted (07-AUG-2001) CBRC, Mass General Hospital, 13th street
Bldg 149, Charlestown, MA 02129, USA
FEATURES Location/Qualifiers
source 1..6352
/db_xref="H-InvDB:HIT000079163"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="8"
/map="8q24.2"
/tissue_type="cartilage"
CDS 448..5328
/note="COL22A1"
/codon_start=1
/product="alpha 1 type XXII collagen"
/protein_id="AAN03620.1"
/translation="MAGLRGNAVAGLLWMLLLWSGGGGCQAQRAGCKSVHYDLVFLLD
TSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGSQEEVK
AAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQDLVLD
AAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRRLC
ENVLCPSVRVEGDRFKHTNGGTKEITGFDLMDLFSVKEILGKRENGAQSSYVRMGSFP
VVQSTEDVFPQGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYGIPQVSIRLDGENKA
VEYNAVGAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSLHIDCALVQTLPIEE
RENIDIQGKTVIGKRLYDSVPIDFDLQRIVIYCDSRHAELETCCDIPSGPCQVTVVTE
PPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVG
APGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVG
MRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGP
SGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGP
EGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFP
GKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPG
EKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSL
FTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGA
AGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDP
GAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAP
GIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGE
RGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTE
GKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPG
ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGE
PGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQ
GPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPG
KEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGE
NGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKS
SQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV
GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQC
AYFASLAARPGNVKGP"
BASE COUNT 1428 a 1729 c 2005 g 1190 t
ORIGIN
1 ggggctggcc cgaggctgcg gcgttctccc caaggaagtg tcttctccgc tttccctgtt
61 cttctgtttc tcacacactt tctatctcat tctgtaactt tcaagccttt ccttctaact
121 gtatgtattt agttacttgt tttcaagctg gttccctctc tggccccctg gcctggggaa
181 agcctccaca cttactgcgg gtcttgttta gagtctgagt ttgtgagatt atttggggca
241 gagtgggcga gtggctgaca ggtgaccccc aggaggagga ttcctggggc tggtgtcttc
301 tcccagctgc tgcttccagt gggcctgggc ccaggactgg acctccgctg gcacccctga
361 gtgcctccct gccaggccat gctgctgtag accctaacag cgtctcttcc tggccaagag
421 aagcctgtcc ccaagaacag gagagccatg gccggcctcc gagggaacgc tgtggctggc
481 ctcctctgga tgctgctgct gtggagtggg ggcggcggct gccaggctca gcgggcaggt
541 tgcaaaagtg tccactacga tctggtcttc ctcctggaca cctcctccag cgtgggcaag
601 gaggactttg agaaggtccg gcagtgggtg gccaacctgg tggacacctt cgaggtgggc
661 cccgaccgca cccgtgtggg ggtcgtgcgc tacagcgacc ggcccaccac ggccttcgag
721 ttgggactct ttggctcgca ggaggaggtc aaggcggctg cccggcgtct cgcctaccac
781 gggggcaaca ccaacacggg agacgcgctc cgctacatca cggcccgcag cttctcccca
841 cacgccggcg gccgccccag ggaccgcgcc tacaagcagg tggccatcct gctcaccgac
901 ggccgcagcc aggacctggt gctggacgcc gcggcggcag cccaccgcgc tggcatccgc
961 atctttgccg tgggcgtggg cgaggcactc aaggaggagc tggaggagat cgcctcagag
1021 cccaagtccg cccacgtctt ccacgtgtcc gacttcaatg ccatcgacaa gatccggggc
1081 aagctgcggc gccgtctttg tgaaaatgtg ctctgtccta gcgttcgtgt agaaggagat
1141 cgctttaagc acaccaatgg aggaaccaag gaaatcacag gttttgacct gatggatttg
1201 ttcagtgtga aggaaatctt ggggaagaga gagaatggag ctcagagttc ctatgtacgg
1261 atgggatcct tccctgtggt gcaaagtact gaggatgtgt tcccccaagg tttacctgat
1321 gagtacgcct ttgtcacaac cttccggttc aggaaaacct ctcggaagga agactggtat
1381 atctggcagg tcatcgacca gtacggcatc ccacaggtct ccatccggct ggatggtgaa
1441 aacaaggcag tcgagtacaa cgctgtgggt gccatgaaag atgctgtcag ggtggtcttc
1501 cgaggttctc gggtcaatga cctctttgac cgggactggc acaagatggc cctgagcatc
1561 caggcccaga acgtctccct gcacattgac tgtgcgctgg tgcagacact acccatcgag
1621 gaacgggaga acattgacat ccagggcaag actgtgattg gcaagcgcct ctacgacagt
1681 gtgcccattg actttgacct acagcggatt gtgatctatt gtgactcgag acacgcagaa
1741 ttggagactt gttgtgatat cccctcgggt ccgtgccagg tgaccgtggt gacagagcct
1801 ccacctccac ccccacccca gcggcctccc accccaggca gtgaacagat tgggtttttg
1861 aagaccatca actgctcctg cccagctgga gagaagggtg aaatgggagt tgctggcccc
1921 atggggctcc ctggtccaaa gggagacata ggagccattg ggccggttgg cgctcctgga
1981 cctaagggag agaaaggtga tgtgggcata ggaccttttg gccaagggga aaagggtgaa
2041 aagggttccc tgggcctgcc cggcccccct gggagagacg gcagcaaagg catgagaggg
2101 gagccaggag agctgggaga gccggggctg ccgggtgagg tcggcatgcg ggggccccaa
2161 ggaccacctg gactccccgg acctcctgga cgtgtcggag ctcctggtct ccaaggagaa
2221 cgaggtgaaa agggaactcg aggagaaaag ggagagcgag gcctggatgg attccctggg
2281 aagcctgggg acacaggaca gcagggcagg cccggccctt ctggtgtggc aggaccccag
2341 ggagaaaagg gtgacgtggg acctgcgggg ccacctggtg taccaggctc agtggtgcag
2401 caagagggct tgaaagggga acagggagct ccaggaccca gaggtcacca aggcgccccc
2461 ggtcctccag gagctcgggg tccaataggc ccagaaggca gggatggacc tcctggtttg
2521 caaggtctcc gagggaagaa aggtgacatg ggaccacctg gaatccctgg attgctgggg
2581 ctgcagggcc ctccaggacc ccctggtgtc ccaggccccc ctggaccggg aggttctccg
2641 ggtttgcctg gagagatcgg cttcccggga aagcctggac ctcctgggcc cacgggaccc
2701 cctggaaagg acgggccaaa tggaccacca ggtccgccag gaaccaaggg agaaccagga
2761 gaaagagggg aagatggtct gcctggaaaa ccaggccttc ggggagaaat tggggagcag
2821 ggcctggcag gccgacctgg agagaaggga gaagcaggcc tcccaggggc tccaggcttc
2881 ccaggtgtga gaggagagaa aggagaccag ggagaaaaag gtgaactggg acttccagga
2941 ctgaaaggtg accgaggtga aaagggtgaa gctggtcctg caggccctcc cgggttacct
3001 ggaactacat ccctgttcac accacatcca cggatgcccg gagaacaagg gcccaaagga
3061 gagaagggcg atccaggcct gcctggggaa ccgggactgc agggccgtcc tggagaattg
3121 gggcctcagg gacccactgg accaccgggt gccaagggac aggaaggtgc acatggggct
3181 cctggagcag ctggaaaccc cggtgctccc ggacatgtcg gtgcccccgg tcccagtggc
3241 cctccaggaa gtgtgggtgc tcccggcctc agaggcaccc cagggaaaga tggggagcgt
3301 ggtgagaagg gtgcagcggg ggaagaaggc agcccagggc cagttggtcc caggggagat
3361 cctggtgctc ctgggctccc tgggccgccc ggaaaaggga aggatggaga gccgggactc
3421 cgtggatcac ctggactccc tggaccccta ggaaccaagg ctgcttgcgg aaaagtcaga
3481 gggtcagaaa actgtgcact gggagggcaa tgtgttaagg gggatcgagg agctcctggg
3541 atccctggtt ctcctggcag ccgtggtgac ccaggcattg gggttgctgg ccctcctggc
3601 ccttccggac caccaggaga caaaggatcc ccgggatcac gaggcttacc tggattccct
3661 ggcccccagg gcccagccgg ccgggacggt gcaccaggaa atccaggaga aagagggcct
3721 cctggcaagc cgggcctctc ttcactactg tctccagggg acataaatct cttggctaag
3781 gatgtgtgca atgactgccc tcctggcccc ccaggcctcc ctggtctacc aggttttaaa
3841 ggggacaaag gtgtcccagg aaagccaggg agagaaggca cagaagggaa aaagggagag
3901 gctgggcctc caggcctacc agggccccca ggaatagctg gaccacaggg aagtcaagga
3961 gaacgtggtg cagatggtga ggttgggcag aaaggtgatc agggtcatcc tggagttcca
4021 ggtttcatgg ggcccccagg gaaccccggg ccaccagggg cagatggaat tgcaggagct
4081 gctggaccac caggaatcca agggtcacct gggaaagaag gccctcctgg cccccaaggc
4141 ccatctggat tacccggaat cccaggagaa gaaggcaaag agggcagaga tggaaagccg
4201 ggtccccctg gagagccggg caaagcagga gagccaggtc taccaggacc agagggtgcc
4261 cgaggcccac ctggcttcaa gggacacaca ggcgattctg gtgcacccgg tccccgggga
4321 gagtctggtg ccatggggct tcctggtcag gaagggttac caggaaaaga tggtgacact
4381 ggacccactg ggccacaggg tccccaagga ccaaggggcc caccgggcaa gaatggatca
4441 ccgggatctc caggagagcc tggcccttca ggaacccctg gccagaaagg aagcaaaggg
4501 gaaaatggca gcccaggact tcctggcttc ctgggtcccc gtgggcctcc gggagaacca
4561 ggagagaaag gagtcccagg caaggagggg gtccctggga agcctggaga gcctggattc
4621 aaaggagaaa ggggagatcc tgggatcaaa ggtgacaaag gacctcctgg tggaaaaggc
4681 cagcctgggg accctggaat cccaggccac aaaggccaca caggcctgat gggtccccaa
4741 ggactacctg gggagaatgg accagttgga cccccagggc ctccaggcca gccgggattt
4801 ccaggactga ggggggagtc tccatccatg gaaaccctgc gtcggcttat tcaagaagag
4861 ctggggaagc agcttgaaac cagactcgcc tacctcctgg cccagatgcc cccggcgtac
4921 atgaagtcat ctcaaggcag acctgggccc ccagggcccc ctggaaaaga tgggcttcca
4981 ggccgggccg gccccatggg ggagccaggt cgtcctgggc aggggggtct ggaaggaccc
5041 tctggaccca taggtcccaa aggtgagcga ggagccaaag gtgacccagg tgcacctgga
5101 gttggcctcc gaggcgagat gggaccccct ggaatcccag gtcaacccgg ggaacctggc
5161 tatgctaaag atggacttcc tgggatccct ggccctcaag gggagacagg accagctgga
5221 catcctggcc tcccaggacc tcccggtccc ccaggccaat gtgacccttc ccagtgtgcc
5281 tacttcgcca gccttgctgc ccggccgggt aatgtgaagg gtccctaaag gactctggaa
5341 agccagaaga ctgcagtgga tttctgaaac ttgaactcag agcccagtgg gaagccagag
5401 gtcttgaaag acttcagcca tgtgttcctt ttttttttct ttcttttatc gtttgctttt
5461 tgttttattt tcttgagaga cctcaaaatt attaaatcca acagacgctg ccggtcggtc
5521 agattattat taatattatt gttgttgtta attattatta ttatttcata tgctgatgct
5581 ttgtgagttc ttttccactc ctttaaagtt gggaaaactt gattcgtggg gcaggagatt
5641 gtttcttcat tcttctgaca gcccccatct gacgcgtaac tgcccatttt aaggaaactc
5701 ttggtgctac aaaaccctga ccagacactt ggcaaattta cctctttctt caaaagaaaa
5761 actttaagaa aatgagccaa tgggcttcat tctcagtcat gcccggagat cacccaggag
5821 aaataataca aacaccacca ctgtccagag agagtaaaga agcagaaaga gaaagaattt
5881 gcaaccatga ggaatgttcc cacctcccga cgggacgtgc atttggaaaa cacagaatca
5941 gccctcaggg tgcactccag ccacctcagt gctctaagct cacagaagtg aaataatgtc
6001 tgtgggttgg caatggcttt gtgggatcat atgtcttggc caaagatggg aaaacctatg
6061 ttgaagaggc agcccttgag tgttaatttg tcttctaaac tgtgtaaggc cccttcaagt
6121 tcctcttgtt ggtttcaatt atattaatta taaaacaagt ggatgtggtg accatccact
6181 tgtgtttccc taatgatggg cagttggcca gggcactgac cagagctggg aaatttgtat
6241 ctccaaggcg gctctgtctc tgaaataaat ggcatcaagt gcatgtgtgt atgcgacatg
6301 ccctgcctga acaggtgctc aataaatcca agtttccttc tcttgaaaaa aa
//