LOCUS AF402000 7629 bp mRNA linear HUM 02-JUL-2002
DEFINITION Homo sapiens talin 2 mRNA, complete cds.
ACCESSION AF402000
VERSION AF402000.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7629)
AUTHORS Pellegrini,L.
TITLE Characterization of talin 2
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7629)
AUTHORS Pellegrini,L., Di Paolo,G. and De Camilli,P.
TITLE Direct Submission
JOURNAL Submitted (24-JUL-2001) Department of Cell Biology, Yale
University, 295 Congress Avenue, New Haven, CT 06510, USA
FEATURES Location/Qualifiers
source 1..7629
/db_xref="H-InvDB:HIT000079120"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 1..7629
/codon_start=1
/product="talin 2"
/protein_id="AAM73764.1"
/translation="MVALSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTG
QASDYGLFLSDEDPRKGIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTV
MVDDSKTVGELLVTICSRIGITNYEEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKM
EKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLY
VQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQR
GAEKRIFQAHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLG
ITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQIS
QLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQFNRTGKAEHGSV
ALPAVMRSGSSGPETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGTINTSMHA
VQQAQDDLSELDSLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAG
DPADTDYTAVGCAITTISSNLTEMSKGVKLLAALMDDEVGSGEDLLRAARTLAGAVSD
LLKAVQPTSGEPRQTVLTAAGSIGQASGDLLRQIGENETDERFQDVLMSLAKAVANAA
AMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLI
EAGKLVDRSVENCVRACQAATTDSELLKQVSAAASVVSQALHDLLQHVRQFASRGEPI
GRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDAEAEIDMENS
KKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGLRVATNAAAQNAIKK
KIVNRLEVAAKQAAAAATQTIAASQNAAVSNKNPAAQQQLVQSCKAVADHIPQLVQGV
RGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAMQLSQCAKNLA
TSLAELRTASQKAHEACGPMEIDSALNTVQTLKNELQDAKMAAVESQLKPLPGETLEK
CAQDLGSTSKAVGSSMAQLLTCAAQGNEHYTGVAARETAQALKTLAQAARGVAASTTD
PAAAHAMLDSARDVMEGSAMLIQEAKQALIAPGDAERQQRLAQVAKAVSHSLNNCVNC
LPGQKDVDVALKSIGESSKKLLVDSLPPSTKPFQEAQSELNQAAADLNQSAGEVVHAT
RGQSGEFAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQIQVIGNLKNISMASSKLLLA
AKSLSVDPGAPNAKNLLAAAARAVTESINQLITLCTQQAPGQKECDNALRELETVKGM
LDNPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALC
GLTEAAAQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNLVDPGSSPSQVL
SAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDF
SEDNRNKCRIATAPLIEAVENLTAFASNPEFVSIPAQISSEGSQAQEPILVSAKTMLE
SSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSID
GINRCIRDIEQASLAAVSQSLATRDDISVEALQEQLTSVVQEIGHLIDPIATAARGEA
AQLGHKVTQLASYFEPLILAAVGVASKILDHQQQMTVLDQTKTLAESALQMLYAAKEG
GGNPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEG
TPPEPKGTFVDYQTTVVKYSKAIAVTAQEMMTKSVTNPEELGGLASQMTSDYGHLAFQ
GQMAAATAEPEEIGFQIRTRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARAV
TEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMFATAGTLNAENSETFADH
RENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSDD
PETQVVLINAIKDVAKALSDLISATKGAASKPVDDPSMYQLKGAAKVMVTNVTSLLKT
VKAVEDEATRGTRALEATIECIKQELTVFQSKDVPEKTSSPEESIRMTKGITMATAKA
VAAGNSCRQEDVIATANLSRKAVSDMLTACKQASFHPDVSDEVRTRALRFGTECTLGY
LDLLEHVLVILQKPTPEFKQQLAAFSKRVAGAVTELIQAAEAMKGTEWVDPEDPTVIA
ETELLGAAASIEAAAKKLEQLKPRAKPKQADETLDFEEQILEAAKSIAAATSALVKSA
SAAQRELVAQGKVGSIPANAADDGQWSQGLISAARMVAAATSSLCEAANASVQGHASE
EKLISSAKQVAASTAQLLVACKVKADQDSEAMRRLQAAGNAVKRASDNLVRAAQKAAF
GKADDDDVVVKTKFVGGIAQIIAAQEEMLKKERELEEARKKLAQIRQQQYKFLPTELR
EDEG"
BASE COUNT 1975 a 2038 c 2181 g 1435 t
ORIGIN
1 atggtggccc tgtccttaaa gatttgtgtg cgccactgca acgtggtgaa gaccatgcag
61 tttgaaccat ctacagctgt gtacgatgcg tgtcgagtca ttcgggaacg ggtgcctgag
121 gcacaaactg ggcaagcttc tgactatgga ctctttcttt cggatgaaga cccgaggaaa
181 gggatttggc tggaagcggg cagaacactg gattactaca tgttgcggaa tggggatatt
241 ttggaatata aaaagaaaca gagacctcag aaaatccgga tgctggatgg atccgtgaag
301 acagtgatgg tggatgattc caagactgtg ggggagctcc tggtcactat ttgtagcaga
361 ataggaataa caaattatga agaatactcc ttaatccaag aaactattga agaaaagaaa
421 gaggaaggaa cgggcacact caaaaaagac aggacactgt tacgagatga gaggaaaatg
481 gagaagttga aggccaagct gcacacagat gatgacctaa attggctgga tcacagccga
541 acattcagag aacaaggagt agatgaaaac gaaacgttgc tgcttagacg gaagttcttt
601 tactctgatc agaatgtaga ttcgagagac cccgtgcagc tgaacttgct ttatgttcag
661 gcacgggatg acatcctgaa tggctctcac cctgtctcct tcgagaaagc ttgtgagttt
721 ggtggatttc aagcccagat acaatttgga cctcatgtgg aacataaaca caaacctgga
781 tttttagacc tgaaggaatt cctgcccaaa gaatatatca agcagagagg agctgaaaag
841 aggatctttc aggcacataa gaactgcgga gagatgagtg agatagaagc caaggtcaag
901 tacgtcaaac tcgcacggtc cctccgcaca tatggcgtgt ccttcttcct ggtgaaggag
961 aagatgaaag gcaagaacaa gctggtgcct cgcctgctgg ggatcaccaa agactcggtg
1021 atgcgcgtgg atgagaagac caaggaagtg ctgcaggagt ggcccctcac caccgtcaag
1081 cgctgggcag cctcacccaa gagcttcaca ctggattttg gggagtatca ggaaagctac
1141 tattcagtac aaaccaccga gggagagcag atatcccagc tgattgcagg ctacattgac
1201 atcatcctga aaaagaaaca aagtaaagat cgatttggac tagaaggtga tgaggagtca
1261 accatgttag aagagtccgt ttccccaaaa aagtccacca tcttgcagca gcagttcaac
1321 cggaccggga aggcagagca cggctcagtg gcgctgccgg ccgtgatgcg ctcgggctcc
1381 agcgggcctg agaccttcaa cgttggcagc atgccctcgc cacagcagca ggtcatggtt
1441 gggcagatgc accgaggcca catgccgcca ctgacttcag cccagcaggc cctgatgggg
1501 accatcaaca caagcatgca cgccgtccag caggcccagg atgatctcag tgagctcgac
1561 tcgctgccac ctctcggcca ggatatggca tctagggtat gggttcagaa caaagtcgac
1621 gaatccaaac acgaaatcca ttctcaagtt gatgctatca cggccggaac ggcttcagtt
1681 gttaacctca cagctggtga ccctgcagac actgactaca cagctgtggg atgtgcgatc
1741 accactattt cttccaacct gacggagatg tccaagggtg tgaagctatt ggccgccctc
1801 atggatgatg aggtgggcag cggggaggac ttgctcagag ctgccaggac cctcgctggg
1861 gcggtgtcag acttgctgaa agctgtgcag cctacttctg gagagcctcg acagacagtt
1921 ttgactgctg ctggcagcat cggacaagcc agtggggatc ttctgagaca gattggagag
1981 aatgagactg atgagcgatt ccaggatgtt ttaatgagtt tggccaaagc tgttgccaat
2041 gcagctgcca tgttggtact aaaggcaaag aatgttgccc aagtggccga agacactgtc
2101 ctacagaaca gggtaattgc tgctgccacc cagtgtgccc tctccacctc ccagcttgtg
2161 gcatgtgcca aggttgtgag ccccactatt agctcccctg tgtgccagga gcagctgatt
2221 gaagcaggga agctggtgga ccgctcggtg gagaactgtg tccgtgcctg ccaggcggcc
2281 actaccgata gtgagctcct gaagcaggtc agcgcagcgg ccagcgtggt cagccaggcc
2341 ctccatgatc tcctgcagca tgtgcggcag tttgccagcc gaggcgagcc catcggccgc
2401 tacgaccagg ctactgacac catcatgtgt gtcaccgaga gcatcttcag ctccatgggt
2461 gacgctggtg aaatggtgcg ccaggcgcgg gttctggccc aagccacatc agacctcgtc
2521 aatgccatga ggtcagatgc agaagccgaa atcgacatgg agaattcaaa gaagctcctg
2581 gcagcagcaa aactcttagc tgactccact gctcgcatgg tggaagctgc aaagggggct
2641 gcagccaacc cagagaatga ggaccagcag caaaggctga gagaagctgc agaaggcctc
2701 cgggtagcaa ccaacgcagc tgcccagaat gctattaaga aaaaaattgt caaccgactg
2761 gaggttgcag ccaagcaggc cgcagcggca gctacacaga ccatcgccgc ctcccagaat
2821 gcagctgttt ccaacaagaa ccctgcggcc cagcagcagc tggtccagag ttgcaaggca
2881 gtggctgatc acatccctca gctggtccag ggagtgaggg ggagccaagc tcaagctgaa
2941 gacctgagtg cccagctggc tctcatcatc tccagccaga acttcctcca gcctggaagc
3001 aagatggtgt cctctgccaa agccgcagtg cccaccgtga gtgaccaggc cgcagccatg
3061 cagctgagcc agtgtgccaa gaacctggcc accagcttgg cggagctgcg taccgcctcg
3121 cagaaggccc atgaagcttg tggtccgatg gaaatcgatt cagctctgaa tacggtgcag
3181 acgcttaaga atgaactgca ggatgccaag atggcagccg tggagagcca gctgaagcca
3241 cttccagggg aaacgctgga aaaatgtgct caggacctgg gaagcacatc caaggcggtg
3301 ggctcctcca tggcacagct gctgacctgt gctgctcaag gcaacgaaca ctacacaggg
3361 gtggctgcta gagagacggc ccaagctctg aaaacactgg cccaggccgc ccgtggagtg
3421 gctgcatcga caaccgaccc cgcggccgcc catgccatgt tagattctgc tcgagacgtg
3481 atggagggct ccgccatgct cattcaagag gccaagcagg ccctgattgc acctggagat
3541 gcagagcgtc aacaaagact ggctcaggtg gctaaagccg tctcacactc cttgaataac
3601 tgcgtaaatt gcctccctgg gcagaaggat gtggacgtgg ccttgaagag catcggggag
3661 tccagcaaga agctgcttgt ggattcgcta cctccaagca cgaagccttt ccaggaagcc
3721 cagagtgaac tgaaccaggc agcagctgat ctgaaccagt ctgctgggga agtggtccat
3781 gccacccggg gccagagtgg agagttcgct gcagcctctg gaaagttcag tgatgatttt
3841 gatgaattcc tcgatgctgg cattgagatg gctggccaag ctcagacaaa agaagaccag
3901 atccaagtga tagggaacct caagaatatc tcgatggcat ccagcaagct gctgttagct
3961 gccaagtctc tctctgtaga tccaggagct cccaatgcga aaaatctcct ggctgcagct
4021 gcaagagctg tgacagagag catcaatcaa ctcatcactc tgtgtaccca acaagctccg
4081 ggccagaaag agtgcgataa tgccctgcgg gagctcgaga ctgtgaaggg gatgttggac
4141 aatcctaatg aacctgttag tgacctctct tactttgact gcattgagag tgtgatggaa
4201 aactccaagg ttctgggtga atcgatggca gggatttcac agaatgccaa gaccggagac
4261 ctccctgcct ttggggaatg tgtggggatt gcatccaagg ctctctgtgg gctgacagag
4321 gctgcagccc aggctgcata cttggttggc atctctgatc caaacagcca ggcaggccac
4381 cagggcctgg tggaccccat ccagtttgcc agggctaacc aggccatcca gatggcatgc
4441 cagaacttgg tggaccctgg cagcagccca tcacaggtcc tgtcagccgc cacaattgtt
4501 gccaagcaca cgtcagcctt gtgtaatgcc tgccgcatcg cctcatccaa gacggccaac
4561 ccagtagcca agaggcactt cgtccagtca gccaaggaag tcgccaacag cactgccaac
4621 ctggtgaaga ccatcaaggc cctggatggg gatttctctg aagacaaccg caataagtgt
4681 cgcatcgcca ccgcaccctt gattgaagct gtggagaacc tgacagcgtt cgcctcaaac
4741 cctgagtttg tcagcattcc tgcccagatc agctccgagg gttcccaggc acaggaacca
4801 atcctggtct cagccaagac catgctggag agttcatcgt acctcattcg cactgcacgc
4861 tctctggcca tcaaccccaa agacccaccc acctggtctg tactggctgg acattcccat
4921 acagtgtccg actccatcaa gagtctcatc acttctatca gggacaaggc ccctggacag
4981 agggagtgtg attactccat cgatggcatc aaccggtgca tccgggacat cgagcaggcc
5041 tcgctggccg ccgtcagcca gagcctggcc acgagggacg acatctctgt ggaggccctg
5101 caggagcagc tgacttcggt ggtccaggaa atcggacacc ttatcgatcc catcgccaca
5161 gcggctcggg gagaagcagc tcagctggga cataaggtga cacaactggc aagctatttt
5221 gagcccttga tcttagccgc agttggtgtg gcctccaaga ttcttgatca tcagcagcag
5281 atgacggtgc tggaccagac caagactctc gcagagtctg ccttgcagat gttgtatgca
5341 gccaaagaag gtggcggaaa ccccaaggca caacacaccc atgacgccat cacagaggcc
5401 gcccagttga tgaaggaagc cgtggatgac atcatggtga cgctgaacga agctgccagt
5461 gaagtggggc tggttggggg catggtggac gccattgcag aagccatgag caagctggat
5521 gaaggcactc ctccagaacc aaagggaaca tttgtcgact atcagacgac tgtggttaaa
5581 tactccaaag ccattgcggt gacagctcag gaaatgatga ctaagtcggt tactaacccg
5641 gaggagttgg gaggactggc ttcacaaatg accagtgact atgggcacct ggctttccag
5701 ggccagatgg cagcagccac ggcggaacca gaggagatcg gattccagat tcgcactcgt
5761 gtgcaggacc tgggccacgg ctgtatcttc ctggtgcaga aggcaggggc cctccaggtc
5821 tgccccacag acagctacac caagagggag ctgatcgaat gcgcccgtgc cgtcacggaa
5881 aaggtctcct tggtgctctc ggctctccag gccgggaaca aaggaaccca ggcatgcatt
5941 acagccgcca ccgctgtgtc tgggatcatt gccgacctgg acaccaccat tatgtttgca
6001 acagcgggga cgctgaatgc agagaacagt gagaccttcg cagaccacag ggagaacatt
6061 ctcaagacgg ccaaggcctt ggtagaagac acgaaactac ttgtgtcagg agctgcgtcc
6121 actcctgaca agctggccca ggcggcccag tcctcagcag ccaccatcac ccagctcgca
6181 gaagtggtca agctgggggc agccagcctg ggctccgacg accccgagac ccaggtggtt
6241 ttgatcaatg ccatcaaaga tgtggccaag gccctttctg atctcatcag tgctaccaag
6301 ggagctgcca gcaagccagt ggacgaccct tccatgtacc agctcaaggg ggctgccaag
6361 gtgatggtga ccaatgtcac ctcgctcctc aagactgtaa aggcagtgga ggatgaggcc
6421 acccggggca ccagggcgct tgaggccaca attgaatgca taaagcagga gcttacggtg
6481 ttccagtcaa aagacgtacc tgaaaagaca tcatcacctg aagaatccat aaggatgacg
6541 aaaggcatca ccatggcaac agccaaagcc gtggcagctg ggaactcatg tagacaggag
6601 gacgtgattg ctactgccaa cctgagccgg aaagccgtgt cagatatgtt gacggcttgc
6661 aagcaagcat ccttccaccc cgatgtcagt gacgaggtga gaaccagagc cttgcgtttc
6721 gggacggagt gcacccttgg ctacttggac ctcctggagc acgtcttggt gattcttcag
6781 aaaccaaccc cagaattcaa gcagcagctg gccgctttct ccaagcgagt cgccggcgct
6841 gtgacagagc tcatccaggc ggcggaagcc atgaaaggaa cagagtgggt ggatccagaa
6901 gacccaactg tcattgcaga aacagagtta ctgggggctg cagcatccat cgaagctgct
6961 gctaagaagt tagagcaact gaagccaaga gcaaaaccaa aacaagcgga tgagaccctg
7021 gactttgagg aacagatctt ggaagctgct aaatccattg ctgctgccac aagcgccctg
7081 gtcaaatcgg cctcagcagc ccagagggag ctggtggccc aaggaaaggt gggctccatc
7141 cctgccaatg ctgcagacga cggacagtgg tcacaggggc tgatttctgc tgcccggatg
7201 gtggcggctg cgaccagcag tctctgtgag gcggccaatg cctccgttca gggacacgcc
7261 agcgaggaga agctcatctc atctgccaag caggtcgccg cttccacggc tcagctgctg
7321 gtggcctgca aggtgaaggc cgaccaggat tcagaggcca tgaggcggct acaggcggca
7381 ggaaatgctg tgaaaagagc ctcagacaat cttgtccgtg cagcccagaa ggcagctttt
7441 ggcaaagctg atgacgacga tgttgtagtg aaaaccaagt ttgtgggggg cattgctcag
7501 atcatcgccg cccaggaaga aatgctaaag aaagagcgag aactggaaga agcaaggaaa
7561 aaactggccc aaatccgcca gcagcagtat aagtttttac ccaccgagct gagggaagat
7621 gagggctaa
//