LOCUS AF398886 2231 bp RNA linear HUM 15-OCT-2001
DEFINITION Homo sapiens ELMO2 precursor RNA, complete cds.
ACCESSION AF398886
VERSION AF398886.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2231)
AUTHORS Gumienny,T., Brugnera,E., Tosello-Trampont,A.-C., Kinchen,J.,
Haney,L., Nishiwaki,K., Walk,S., Francis,R., Schedl,T., Qin,Y., Van
Aelst,L., Hengartner,M.O. and Ravichandran,K.S.
TITLE CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is
required for phagocytosis and cell migration
JOURNAL Cell 107 (1), 27-41 (2001)
PUBMED 11595183
REFERENCE 2 (bases 1 to 2231)
AUTHORS Brugnera,E. and Ravichandran,K.S.
TITLE Direct Submission
JOURNAL Submitted (15-JUL-2001) Beirne Carter Center for Immunology,
University of Virginia, MR4 Building, Rm 4072D, Box 801386,
Charlottesville, VA 22908-1386, USA
FEATURES Location/Qualifiers
source 1..2231
/db_xref="H-InvDB:HIT000330087"
/organism="Homo sapiens"
/mol_type="transcribed RNA"
/db_xref="taxon:9606"
/chromosome="20"
/note="obtained from EST BEO17955"
precursor_RNA <1..>2231
/note="partially processed mRNA"
mRNA join(<1..119,188..>2231)
/product="ELMO2"
CDS join(1..119,188..2231)
/codon_start=1
/product="ELMO2"
/protein_id="AAL14467.1"
/translation="MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLP
NPEYYTLRYADGPQLYITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLD
AMKELAKLSADVTFATEFINMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDH
GIVSWDMVSITFIKQIAGYVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVG
QLISHLQVSNQEIQTYAIALINALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNR
PIKTEMAHQLYVLQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAP
GSGTEKRKAMYTKDYKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIV
LENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFG
ICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEIL
RLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQER
FWYCRLALNHKVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSAL
KQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTL
LSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYHYG"
BASE COUNT 602 a 589 c 555 g 485 t
ORIGIN
1 atgccaccac cgtcagacat tgtcaaagtg gccattgagt ggccaggtgc taacgcccag
61 ctccttgaaa tcgaccagaa acggcccctg gcatccatta tcaaggaagt ttgtgatggg
121 taggttgaaa tggacctcgt tttcaacagt ggcagctccg actgaaagag cactcctaca
181 ccttgaggtg gtcgttgcca aacccagagt attataccct ccgttatgca gatggtcctc
241 agctgtacat caccgaacag actcgcagtg acattaagaa tgggacaatc ttacaactgg
301 ctatctcccc gtcccgggct gcacgccagc tgatggagag gacccagtca tccaacatgg
361 agacccggct ggatgccatg aaggagctgg ccaagctctc tgccgacgtg actttcgcta
421 ctgagttcat caacatggat ggcatcattg tgctgacaag gctcgtggaa agtggaacca
481 agctcttgtc ccactacagt gagatgctgg cattcaccct gactgccttc ctagagctca
541 tggaccatgg cattgtctcc tgggacatgg tttcaatcac ctttattaag cagattgcag
601 ggtatgtgag ccagcccatg gtggacgtgt caatccttca gaggtccctg gccatcctgg
661 agagcatggt cttgaacagc cagagtctgt accagaagat agccgaggaa atcaccgtgg
721 gacagctcat ctcacacctc caggtctcca accaggagat tcagacctac gccattgcac
781 tgattaatgc actttttctg aaggctcctg aggacaaacg acaggatatg gcaaatgcat
841 ttgcacagaa gcatctccgg tctataatcc tgaatcatgt gatccgaggg aaccgcccca
901 tcaaaactga gatggcccat cagctatatg tccttcaagt cctaaccttt aaccttctgg
961 aagaaaggat gatgaccaag atggacccca atgaccaggc tcaaagggac atcatatttg
1021 aactgaggag gattgcattt gacgcagagt ctgatcctag caatgcccct gggagtggga
1081 ccgaaaaacg caaagccatg tacacaaagg actacaaaat gctgggattt accaaccaca
1141 tcaatccagc catggacttt acccagactc ctcctggaat gctggccttg gacaacatgc
1201 tgtacttggc taaagtccac caggacacct acatccggat tgtcttggag aacagtagcc
1261 gggaagacaa acatgaatgc ccctttggcc gcagtgccat tgagctcacc aaaatgctct
1321 gtgaaatcct gcaggttggg gaactaccaa atgaaggacg caatgactac cacccgatgt
1381 tctttaccca tgaccgagcc tttgaagagc tctttggaat ctgcatccag ctgttgaaca
1441 agacctggaa ggagatgagg gcaacagcag aggacttcaa caaggttatg caagtcgtcc
1501 gagagcaaat cactcgagct ttgccctcca aacccaactc tttggatcag ttcaagagca
1561 aattgcgtag cctgagttac tctgagattc tacgactgcg ccagtctgag aggatgagtc
1621 aggatgactt ccagtccccg ccaattgtgg agctgaggga gaagatccag cccgagatcc
1681 ttgagctgat caagcagcag cgcctgaacc ggctctgtga gggcagcagc ttccgaaaga
1741 ttgggaaccg ccgaaggcaa gaacggttct ggtactgccg gttggcactg aaccacaagg
1801 tccttcacta tggtgacttg gatgacaacc cacaagggga ggtgacattt gaatccctgc
1861 aggagaaaat tcctgttgca gacattaagg ccattgtcac tgggaaagat tgtccccaca
1921 tgaaagagaa aagtgctctg aaacagaaca aggaggtgtt ggaattggcc ttctccatcc
1981 tgtatgaccc tgatgagacc ttaaacttca tcgcacctaa taaatatgag tactgcatct
2041 ggattgacgg cctcagtgcc cttctgggga aggacatgtc cagtgagctg accaagagtg
2101 acctggacac cctgctgagc atggagatga agctgcggct cctggacctg gagaacatcc
2161 agattcccga agccccaccc cccatcccca aggagcccag cagctatgac tttgtctatc
2221 actatggctg a
//