LOCUS AF391556 5448 bp mRNA linear HUM 01-JAN-2003
DEFINITION Homo sapiens myosin IIIB variant MYO3B.3 (MYO3B) mRNA, complete
cds, alternatively spliced.
ACCESSION AF391556
VERSION AF391556.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5448)
AUTHORS Dose,A.C.
TITLE A new class III myosin expressed in retina is a potential candidate
for ARRP and Bardet-Biedl syndrome
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 5448)
AUTHORS Dose,A.C.
TITLE Direct Submission
JOURNAL Submitted (17-APR-2001) MCB, UC Berkeley, LSA-335/3200, Berkeley,
CA 94720-3200, USA
FEATURES Location/Qualifiers
source 1..5448
/db_xref="H-InvDB:HIT000078844"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2q31.1-q31.2"
gene 1..5448
/gene="MYO3B"
CDS 144..4088
/gene="MYO3B"
/note="alternatively spliced; from mRNA missing exons 28
and 33; expressed in retina and kidney"
/codon_start=1
/product="myosin IIIB variant MYO3B.3"
/protein_id="AAO13801.1"
/translation="MKHLYGLFHYNPMMLGLESLPDPTDTWEIIETIGKGTYGKVYKV
TNKRDGSLAAVKILDPVSDMDEEIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQL
WLVLELCNGGSVTELVKGLLRCGQRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGN
NILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCD
VWSLGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTLLHPEKWCEEFNHFISQCLIK
DFERRPSVTHLLDHPFIKGVHGKVLFLQKQLAKVLQDQKHQNPVAKTRHERMHTRRPY
HVEDAEKYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIY
SPQFSRLYHGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIV
QHLTFLGKANNQTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMG
ARISEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETG
RVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQH
QTDKSEVPNAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDA
MSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCIN
IANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEE
SRFPQATDQTLVDKFEDNLRCKYFWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTL
PADVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTL
EVIRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRER
VLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILEK
SRLDHWVLGKTKVFLKYYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRYKKVREKRE
KGAIAIQSGDTSNQSSGPHSPVAAGTRGSAEVQDCSEPGDHKVLRGSVHRRSHSQAES
NNGRTQTSSNSPAVTEKNGHSQAQSSPKGCDIFAGHANKHSVSGTDLLSSRICHPAPD
QQGLSLWGAPQKPGSENGLAQKHRTPRRRCQQPKMLSSPEDTMYYNQLNGTLEYQGSK
RKPRKLGQIKVLDGEDEYYKSLSPVDCIPEENNSAHPSFFSSSSKGDSFAQH"
BASE COUNT 1538 a 1250 c 1233 g 1427 t
ORIGIN
1 ctagatcgaa agtcctttgg taatgatgtg tcatacattc tagtcatcaa agacaccatt
61 ttctgggcct gaagtgttct gctggttttt ggaggaatga gaatccaatc tctcataagc
121 cggattcaga aaataggtca tcgatgaaac atctgtatgg attatttcac tataatccta
181 tgatgcttgg acttgaatca cttccagatc ccacagacac ctgggaaatt atagagacca
241 ttggtaaagg cacctatggc aaagtctaca aggtaactaa caagagagat gggagcctgg
301 ctgcagtgaa aattctggat ccagtcagtg atatggatga agaaattgag gcagaataca
361 acattttgca gttccttcct aatcatccca atgttgtaaa gttttatggg atgttttaca
421 aagcggatca ctgtgtaggg ggacagctgt ggctggtcct ggagctgtgt aatgggggct
481 cagtcactga gcttgtcaaa ggtctactca gatgtggcca gcggttggat gaagcaatga
541 tctcatacat cttgtacggg gccctcttgg gccttcagca tttgcacaac aaccgaatca
601 tccaccgtga tgtgaagggg aataacattc ttctgacaac agaaggagga gttaagctcg
661 ttgactttgg tgtttcagct caactcacca gtacacgtct gcggagaaac acatctgttg
721 gcaccccatt ctggatggcc cctgaggtca ttgcctgtga gcagcagtat gactcttcct
781 atgacgctcg ctgtgacgtc tggtccttgg ggatcacagc tattgaactg ggggatggag
841 accctcccct ctttgacatg catcctgtga aaacactctt taagattcca agaaatcctc
901 cacctacttt acttcatcca gaaaaatggt gtgaagaatt caaccacttt atttcacagt
961 gtcttattaa ggattttgaa aggcgacctt ccgtcacaca tctccttgac cacccattta
1021 ttaaaggagt acatggaaaa gttctgtttc tgcaaaaaca gctggccaag gttctccaag
1081 accagaagca tcaaaatcct gttgctaaaa ccaggcatga gaggatgcat accagaagac
1141 cttatcatgt ggaagatgct gaaaaatact gccttgagga tgatttggtc aacctagagg
1201 ttctggatga ggatacaatt atccatcagt tgcagaaacg ttatgcagac ttgctaattt
1261 acacatatgt tggagacatc ttaattgcct taaacccctt ccagaatcta agcatatact
1321 ctccacagtt ttccagactt tatcatgggg tgaaacgcgc ctccaatccc ccccacatat
1381 ttgcatcagc agatgctgct taccagtgca tggttactct cagcaaagac cagtgcattg
1441 tcatcagcgg agagagtggc tctgggaaga cagaaagcgc ccacctgatt gttcaacatt
1501 tgactttctt gggaaaggcc aataatcaga ccttgagaga gaaaattcta caagtcaact
1561 ccctggtgga agcctttggg aactcatgca ctgccatcaa tgacaactcg agccgttttg
1621 gaaaatatct ggaaatgatg tttacaccaa ctggagttgt gatgggggca agaatctctg
1681 aatatctcct ggaaaaatcc agagttataa aacaggcagc gagagagaaa aattttcata
1741 tattttacta tatttatgct ggtcttcatc accaaaagaa gctttctgat ttcagacttc
1801 ctgaggaaaa acctcctagg tacatagctg atgaaactgg aagggtgatg cacgacataa
1861 cttccaagga gtcttacaga agacaattcg aagcaattca gcattgcttc aggattatag
1921 ggttcacgga caaagaggtg cactcagtgt acagaatttt ggctgggatt ttgaatattg
1981 ggaacattga gttcgcagct atttcctctc aacatcagac tgataaaagt gaggtgccca
2041 atgctgaagc tttgcaaaat gctgcctctg ttctgtgcat tagccctgaa gagctccagg
2101 aggccctcac ctcccactgt gtggtcaccc ggggcgagac catcatccgt gccaacactg
2161 tagacagggc tgcggacgtt cgagacgcca tgtccaaagc cctgtatggg aggctcttca
2221 gctggattgt gaatcgcatt aatacactcc tgcagccaga cgaaaacata tgtagtgcag
2281 gaggtggaat gaatgtgggg atcttggata tctttggatt cgagaatttt cagagaaatt
2341 catttgagca gctctgcata aacatcgcca atgagcaaat ccagtactat ttcaatcagc
2401 atgtttttgc tcttgagcag atggaatatc agaatgaagg cattgatgct gtacccgtgg
2461 aatatgagga caaccgcccg ctcttggaca tgttcctcca gaaacccctg ggactgcttg
2521 cacttttgga tgaggaaagt cggtttcccc aagcaactga ccagaccctg gttgataaat
2581 ttgaagataa tctacgatgc aaatacttct ggaggcccaa aggagtggaa ctgtgctttg
2641 gcattcagca ttatgctgga aaggtattat atgatgcttc tggggttctt gagaaaaata
2701 gagacactct ccctgccgat gtggttgtgg tcctgagaac gtcagaaaac atgcttcttc
2761 agcagctctt ctcaatccct ctgaccaaaa caggtaattt ggcccagaca agagctagga
2821 taacagtggc ctcaagttct ttgcctccac atttcagtgc tgggaaagcc aaggtggaca
2881 ctctggaggt gatacggcat ccggaagaaa ccaccaacat gaagaggcaa actgtggctt
2941 cttacttccg gtattctctg atggacctgc tctccaaaat ggtggttgga cagccccact
3001 ttgtgcgctg cattaaaccc aatgatgacc gagaggccct gcagttctct cgagagaggg
3061 tgctggccca gctccgctcc acagggattc tggagacagt cagcatccgc cgccagggct
3121 attcccaccg catccttttt gaagaatttg tgaaaaggta ttattacttg gcattcacag
3181 cacatcaaac acctcttgct agcaaagaga gctgtgtggc tatcttggaa aagtccagat
3241 tagatcactg ggtgctggga aaaacaaagg tttttctcaa atattaccat gttgagcaat
3301 taaatttgct gcttcgagaa gtcataggca gagtggttgt gctgcaggca tataccaagg
3361 ggtggcttgg agccaggaga tacaaaaagg tcagagagaa gagagagaag ggagccattg
3421 ccatccagtc aggggacact tcaaaccaaa gcagtgggcc acattccccc gtcgcagcag
3481 gtacgagggg aagtgccgag gttcaagact gcagcgagcc tggtgaccat aaagttctca
3541 ggggctctgt acatcgtagg agccattcac aagcagaatc caacaatggc cgtacacaga
3601 cttcaagcaa ctctcctgct gtcacagaga aaaatgggca ttcacaagcc cagagttctc
3661 caaaagggtg cgatatcttc gcaggacatg caaacaagca ctcggtttct gggactgatt
3721 tgctgtcttc tcggatatgc catcctgctc cagatcagca aggattgagt ctctggggag
3781 cccctcaaaa gcctggttca gaaaatggtc ttgcacagaa gcatcgaaca cctcgccgac
3841 gatgtcagca gcccaaaatg ctgagtagcc ctgaggacac catgtactat aaccagttaa
3901 atggaactct agaatatcaa gggagcaaga ggaagccaag aaaacttggc caaatcaaag
3961 tacttgatgg ggaagatgaa tattacaaat ctctgtcacc agtggactgt atccctgagg
4021 agaacaactc agcccaccct tccttttttt cttcatcctc aaaaggagac tcttttgctc
4081 aacattaaat tgtgcttcct aaccctaaat ctgtccagag taggaacatt catggtaatc
4141 gactgtctgt cattgcgtaa gaaagcactg atatggggtc agcttctttg gacatatggt
4201 ccatgcctga accttactga accacttgca gattccaaaa catcttatcc tatcctctac
4261 cactctccca catgtgttgt gcagcctgag ctgggcgctg ccttcctttc tcatcccatg
4321 gggccctgtg ggacactgag aacaccttta caatagttta aacagtcatt catgccccca
4381 gtgtctagga agataacagc cagtctcacc ccagtctaat catggaccct gataatattg
4441 cttgattttt cctatcaagt tacttttcaa tccattcaga atctgcccca gtggagaccc
4501 aggagttcct ttcctgcact cttctccatc ctcccacctt tgctgggctt ttctatcact
4561 cccacctccc ccagagtcag ggctccattg ctgagtgccc catcctggag gattggcccc
4621 aagatctcct agaacaggat aattgcctgt gtttaggcag ataggcctaa atctttcaga
4681 ttctttctac aaggcaaata acccctctct tgttaattat gatgctgaga aagcctctgt
4741 ctctttattt caccttgcca agacacccac actactttgg tgatgaaaag aaaggaatga
4801 gagggaaagt ttggacctgt cactttggtg acagggaaag tccaggtcac tttattctgt
4861 aactctccat tcactggtca aataactcca tgaggctatc agtggctaca gtggaaggac
4921 ctgatcttgt ccatctttgt gtgcacagag cctagcacag ggcttggtag agggtatatc
4981 tagtgaatgg agaatacatg gagaaactta actaagttac acaagcatat ctgacaggaa
5041 tgttaccttc aattgtatgt tacatatgat tagtcacttt tcatacacta taacctctga
5101 tttttcactc aagtttgggc tgattatatt gtaatgatgt tagataatac tcaacatgat
5161 tcagtatgac aaactttttt gagcacctac tttatataaa acatgacaaa ttgcagtgtg
5221 atgtaatcaa aaacaaagaa gccctataag accatttctc tagaacagat gttcttaata
5281 tttttcttac tctaaaatat gtggtagata gtatgcaaga aaagccgggt gcggtggctc
5341 aggcctgtaa tcccagcact ttgggaggcc aagatgggcg gatcatgaag tcaggagttc
5401 gagaccagcc tgaccaacat ggtgaaaccc cgtctctact aaaaaaaa
//