LOCUS AF391554 5479 bp mRNA linear HUM 01-JAN-2003
DEFINITION Homo sapiens myosin IIIB variant MYO3B.1 (MYO3B) mRNA, complete
cds, alternatively spliced.
ACCESSION AF391554
VERSION AF391554.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5479)
AUTHORS Dose,A.C. and Burnside,B.
TITLE A new class III myosin expressed in retina is a potential candidate
for either ARRP or Bardet-Biedl syndrome
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 5479)
AUTHORS Dose,A.C.
TITLE Direct Submission
JOURNAL Submitted (17-APR-2001) MCB, UC Berkeley, LSA-335/3200, Berkeley,
CA 94720-3200, USA
FEATURES Location/Qualifiers
source 1..5479
/db_xref="H-InvDB:HIT000078842"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2q31.1-q31.2"
gene 1..5479
/gene="MYO3B"
CDS 144..3899
/gene="MYO3B"
/note="alternatively spliced; from mRNA missing exon 28;
expressed in retina and kidney"
/codon_start=1
/product="myosin IIIB variant MYO3B.1"
/protein_id="AAO13799.1"
/translation="MKHLYGLFHYNPMMLGLESLPDPTDTWEIIETIGKGTYGKVYKV
TNKRDGSLAAVKILDPVSDMDEEIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQL
WLVLELCNGGSVTELVKGLLRCGQRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGN
NILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCD
VWSLGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTLLHPEKWCEEFNHFISQCLIK
DFERRPSVTHLLDHPFIKGVHGKVLFLQKQLAKVLQDQKHQNPVAKTRHERMHTRRPY
HVEDAEKYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIY
SPQFSRLYHGVKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIV
QHLTFLGKANNQTLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMG
ARISEYLLEKSRVIKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETG
RVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQH
QTDKSEVPNAEALQNAASVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDA
MSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCIN
IANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEE
SRFPQATDQTLVDKFEDNLRCKYFWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTL
PADVVVVLRTSENMLLQQLFSIPLTKTGNLAQTRARITVASSSLPPHFSAGKAKVDTL
EVIRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRER
VLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILEK
SRLDHWVLGKTKVFLKYYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRYKKVREKRE
KGAIAIQSGDTSNQSSGPHSPVAAGTRGSAEVQDCSEPGDHKVLRGSVHRRSHSQAES
NNGRTQTSSNSPAVTEKNGHSQAQSSPKGCDIFAGHANKHSVSGTDLLSSRICHPAPD
QQGLSLWGAPQKPAFPHYGCNFYGFRKWSCTEASNTSPTMSAAQNAE"
BASE COUNT 1545 a 1257 c 1238 g 1439 t
ORIGIN
1 ctagatcgaa agtcctttgg taatgatgtg tcatacattc tagtcatcaa agacaccatt
61 ttctgggcct gaagtgttct gctggttttt ggaggaatga gaatccaatc tctcataagc
121 cggattcaga aaataggtca tcgatgaaac atctgtatgg attatttcac tataatccta
181 tgatgcttgg acttgaatca cttccagatc ccacagacac ctgggaaatt atagagacca
241 ttggtaaagg cacctatggc aaagtctaca aggtaactaa caagagagat gggagcctgg
301 ctgcagtgaa aattctggat ccagtcagtg atatggatga agaaattgag gcagaataca
361 acattttgca gttccttcct aatcatccca atgttgtaaa gttttatggg atgttttaca
421 aagcggatca ctgtgtaggg ggacagctgt ggctggtcct ggagctgtgt aatgggggct
481 cagtcactga gcttgtcaaa ggtctactca gatgtggcca gcggttggat gaagcaatga
541 tctcatacat cttgtacggg gccctcttgg gccttcagca tttgcacaac aaccgaatca
601 tccaccgtga tgtgaagggg aataacattc ttctgacaac agaaggagga gttaagctcg
661 ttgactttgg tgtttcagct caactcacca gtacacgtct gcggagaaac acatctgttg
721 gcaccccatt ctggatggcc cctgaggtca ttgcctgtga gcagcagtat gactcttcct
781 atgacgctcg ctgtgacgtc tggtccttgg ggatcacagc tattgaactg ggggatggag
841 accctcccct ctttgacatg catcctgtga aaacactctt taagattcca agaaatcctc
901 cacctacttt acttcatcca gaaaaatggt gtgaagaatt caaccacttt atttcacagt
961 gtcttattaa ggattttgaa aggcgacctt ccgtcacaca tctccttgac cacccattta
1021 ttaaaggagt acatggaaaa gttctgtttc tgcaaaaaca gctggccaag gttctccaag
1081 accagaagca tcaaaatcct gttgctaaaa ccaggcatga gaggatgcat accagaagac
1141 cttatcatgt ggaagatgct gaaaaatact gccttgagga tgatttggtc aacctagagg
1201 ttctggatga ggatacaatt atccatcagt tgcagaaacg ttatgcagac ttgctaattt
1261 acacatatgt tggagacatc ttaattgcct taaacccctt ccagaatcta agcatatact
1321 ctccacagtt ttccagactt tatcatgggg tgaaacgcgc ctccaatccc ccccacatat
1381 ttgcatcagc agatgctgct taccagtgca tggttactct cagcaaagac cagtgcattg
1441 tcatcagcgg agagagtggc tctgggaaga cagaaagcgc ccacctgatt gttcaacatt
1501 tgactttctt gggaaaggcc aataatcaga ccttgagaga gaaaattcta caagtcaact
1561 ccctggtgga agcctttggg aactcatgca ctgccatcaa tgacaactcg agccgttttg
1621 gaaaatatct ggaaatgatg tttacaccaa ctggagttgt gatgggggca agaatctctg
1681 aatatctcct ggaaaaatcc agagttataa aacaggcagc gagagagaaa aattttcata
1741 tattttacta tatttatgct ggtcttcatc accaaaagaa gctttctgat ttcagacttc
1801 ctgaggaaaa acctcctagg tacatagctg atgaaactgg aagggtgatg cacgacataa
1861 cttccaagga gtcttacaga agacaattcg aagcaattca gcattgcttc aggattatag
1921 ggttcacgga caaagaggtg cactcagtgt acagaatttt ggctgggatt ttgaatattg
1981 ggaacattga gttcgcagct atttcctctc aacatcagac tgataaaagt gaggtgccca
2041 atgctgaagc tttgcaaaat gctgcctctg ttctgtgcat tagccctgaa gagctccagg
2101 aggccctcac ctcccactgt gtggtcaccc ggggcgagac catcatccgt gccaacactg
2161 tagacagggc tgcggacgtt cgagacgcca tgtccaaagc cctgtatggg aggctcttca
2221 gctggattgt gaatcgcatt aatacactcc tgcagccaga cgaaaacata tgtagtgcag
2281 gaggtggaat gaatgtgggg atcttggata tctttggatt cgagaatttt cagagaaatt
2341 catttgagca gctctgcata aacatcgcca atgagcaaat ccagtactat ttcaatcagc
2401 atgtttttgc tcttgagcag atggaatatc agaatgaagg cattgatgct gtacccgtgg
2461 aatatgagga caaccgcccg ctcttggaca tgttcctcca gaaacccctg ggactgcttg
2521 cacttttgga tgaggaaagt cggtttcccc aagcaactga ccagaccctg gttgataaat
2581 ttgaagataa tctacgatgc aaatacttct ggaggcccaa aggagtggaa ctgtgctttg
2641 gcattcagca ttatgctgga aaggtattat atgatgcttc tggggttctt gagaaaaata
2701 gagacactct ccctgccgat gtggttgtgg tcctgagaac gtcagaaaac atgcttcttc
2761 agcagctctt ctcaatccct ctgaccaaaa caggtaattt ggcccagaca agagctagga
2821 taacagtggc ctcaagttct ttgcctccac atttcagtgc tgggaaagcc aaggtggaca
2881 ctctggaggt gatacggcat ccggaagaaa ccaccaacat gaagaggcaa actgtggctt
2941 cttacttccg gtattctctg atggacctgc tctccaaaat ggtggttgga cagccccact
3001 ttgtgcgctg cattaaaccc aatgatgacc gagaggccct gcagttctct cgagagaggg
3061 tgctggccca gctccgctcc acagggattc tggagacagt cagcatccgc cgccagggct
3121 attcccaccg catccttttt gaagaatttg tgaaaaggta ttattacttg gcattcacag
3181 cacatcaaac acctcttgct agcaaagaga gctgtgtggc tatcttggaa aagtccagat
3241 tagatcactg ggtgctggga aaaacaaagg tttttctcaa atattaccat gttgagcaat
3301 taaatttgct gcttcgagaa gtcataggca gagtggttgt gctgcaggca tataccaagg
3361 ggtggcttgg agccaggaga tacaaaaagg tcagagagaa gagagagaag ggagccattg
3421 ccatccagtc aggggacact tcaaaccaaa gcagtgggcc acattccccc gtcgcagcag
3481 gtacgagggg aagtgccgag gttcaagact gcagcgagcc tggtgaccat aaagttctca
3541 ggggctctgt acatcgtagg agccattcac aagcagaatc caacaatggc cgtacacaga
3601 cttcaagcaa ctctcctgct gtcacagaga aaaatgggca ttcacaagcc cagagttctc
3661 caaaagggtg cgatatcttc gcaggacatg caaacaagca ctcggtttct gggactgatt
3721 tgctgtcttc tcggatatgc catcctgctc cagatcagca aggattgagt ctctggggag
3781 cccctcaaaa gcctgccttt ccacattacg gatgtaactt ttatgggttc agaaaatggt
3841 cttgcacaga agcatcgaac acctcgccga cgatgtcagc agcccaaaat gctgagtagc
3901 cctgaggaca ccatgtacta taaccagtta aatggaactc tagaatatca agggagcaag
3961 aggaagccaa gaaaacttgg ccaaatcaaa gtacttgatg gggaagatga atattacaaa
4021 tctctgtcac cagtggactg tatccctgag gagaacaact cagcccaccc ttcctttttt
4081 tcttcatcct caaaaggaga ctcttttgct caacattaaa ttgtgcttcc taaccctaaa
4141 tctgtccaga gtaggaacat tcatggtaat cgactgtctg tcattgcgta agaaagcact
4201 gatatggggt cagcttcttt ggacatatgg tccatgcctg aaccttactg aaccacttgc
4261 agattccaaa acatcttatc ctatcctcta ccactctccc acatgtgttg tgcagcctga
4321 gctgggcgct gccttccttt ctcatcccat ggggccctgt gggacactga gaacaccttt
4381 acaatagttt aaacagtcat tcatgccccc agtgtctagg aagataacag ccagtctcac
4441 cccagtctaa tcatggaccc tgataatatt gcttgatttt tcctatcaag ttacttttca
4501 atccattcag aatctgcccc agtggagacc caggagttcc tttcctgcac tcttctccat
4561 cctcccacct ttgctgggct tttctatcac tcccacctcc cccagagtca gggctccatt
4621 gctgagtgcc ccatcctgga ggattggccc caagatctcc tagaacagga taattgcctg
4681 tgtttaggca gataggccta aatctttcag attctttcta caaggcaaat aacccctctc
4741 ttgttaatta tgatgctgag aaagcctctg tctctttatt tcaccttgcc aagacaccca
4801 cactactttg gtgatgaaaa gaaaggaatg agagggaaag tttggacctg tcactttggt
4861 gacagggaaa gtccaggtca ctttattctg taactctcca ttcactggtc aaataactcc
4921 atgaggctat cagtggctac agtggaagga cctgatcttg tccatctttg tgtgcacaga
4981 gcctagcaca gggcttggta gagggtatat ctagtgaatg gagaatacat ggagaaactt
5041 aactaagtta cacaagcata tctgacagga atgttacctt caattgtatg ttacatatga
5101 ttagtcactt ttcatacact ataacctctg atttttcact caagtttggg ctgattatat
5161 tgtaatgatg ttagataata ctcaacatga ttcagtatga caaacttttt tgagcaccta
5221 ctttatataa aacatgacaa attgcagtgt gatgtaatca aaaacaaaga agccctataa
5281 gaccatttct ctagaacaga tgttcttaat atttttctta ctctaaaata tgtggtagat
5341 agtatgcaag aaaagccggg tgcggtggct caggcctgta atcccagcac tttgggaggc
5401 caagatgggc ggatcatgaa gtcaggagtt cgagaccagc ctgaccaaca tggtgaaacc
5461 ccgtctctac taaaaaaaa
//