LOCUS AF389428 5943 bp mRNA linear HUM 17-SEP-2002
DEFINITION Homo sapiens semaphorin 6D isoform 3 (SEMA6D) mRNA, complete cds;
alternatively spliced.
ACCESSION AF389428
VERSION AF389428.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5943)
AUTHORS Qu,X., Wei,H., Zhai,Y., Que,H., Chen,Q., Tang,F., Wu,Y., Xing,G.,
Zhu,Y., Liu,S., Fan,M. and He,F.
TITLE Identification, characterization, and functional study of the two
novel human members of the semaphorin gene family
JOURNAL J. Biol. Chem. 277 (38), 35574-35585 (2002)
PUBMED 12110693
REFERENCE 2 (bases 1 to 5943)
AUTHORS Qu,X., Wei,H., Zhai,Y., Yu,Y., Tang,F. and He,F.
TITLE Homo sapiens semaphorin 6D isoform 3 (SEMA6D.3) mRNA, complete cds
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 5943)
AUTHORS Qu,X., Wei,H., Zhai,Y., Yu,Y., Tang,F. and He,F.
TITLE Direct Submission
JOURNAL Submitted (04-JUN-2001) Department of Genomics and Proteomics,
Beijing Institute of Radiation Medicine, Taiping Road 27, Beijing,
Beijing 100850, P.R. China
FEATURES Location/Qualifiers
source 1..5943
/db_xref="H-InvDB:HIT000078816"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="15"
/map="15q21.1"
/tissue_type="brain"
/dev_stage="adult"
gene 1..5943
/gene="SEMA6D"
CDS 440..3493
/gene="SEMA6D"
/note="axon guidance family member; belongs to class 6 of
semaphorin gene family; semaphorin 6D.3; alternative
spliced"
/codon_start=1
/product="semaphorin 6D isoform 3"
/protein_id="AAM69451.1"
/translation="MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVF
RGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQ
QDRENCAMKGKHKDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEI
SGLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWI
KEPHFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTS
FLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMD
DIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSF
IKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLK
VLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCII
RIPLSRCERYGSCKKSCIASRDPYCGWLSQGSCGRVTPGMLAEGYEQDTEFGNTAHLG
DCHEILPTSTTPDYKIFGGPTSGVRWEVQSGESNQMVHMNVLITCVFAAFVLGAFIAG
VAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSPKLY
SNLLTSRKELPPNGDTKSMVMDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSEKAH
GHGASRKETPQFFPSSPPPHSPLSHGHIPSAIVLPNATHDYNTSFSNSNAHKAEKKLQ
NIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLNDPNSNPKAIMGDIQMAHQNLMLDPM
GSMSEVPPKVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVPMTSLERQRGYHKNSSQ
RHSISAMPKNLNSPNGVLLSRQPSMNRGGYMPTPTGAKVDYIQGTPVSVHLQPSLSRQ
SSYTSNGTLPRTGLKRTPSLKPDVPPKPSFVPQTPSVRPLNKYTY"
BASE COUNT 1714 a 1361 c 1232 g 1636 t
ORIGIN
1 gcggccgctt cccaccgtcc ctctcccctt actggcagag cgcgctgcgg gcggactccc
61 gggcccggag cagcccaccg gccaccccac cgcccacccg gctcccggtg tctcctcccg
121 gccgctctac ccagcaactt tccgtgcttt gttccccgac tggaaatgct ttacggaagc
181 gtcttggaca gggtctccgc caggcgacaa gagctcggtg ctgagatgtg ttacgttctc
241 atctccccat caattatgga tggaaacaaa taaggaagag tcaattttgc tgagcccctt
301 ctccggcaac gagaggcgtt ctgcagccgg gagggagccg ccgctcgcgc cggcagccgc
361 tggcaggggc atggtgagga ggaaggtagc tcagtggcat ttctgagcag gggccaccct
421 gacttcacct tggcccacca tgagggtctt cctgctttgt gcctacatac tgctgctgat
481 ggtttcccag ttgagggcag tcagctttcc tgaagatgat gaacccctta atactgtcga
541 ctatcactat tcaaggcaat atccggtttt tagaggacgc ccttcaggca atgaatcgca
601 gcacaggctg gactttcagc tgatgttgaa aattcgagac acactttata ttgctggcag
661 ggatcaagtt tatacagtaa acttaaatga aatgcccaaa acagaagtaa tacccaacaa
721 gaaactgaca tggcgatcaa gacaacagga tcgagaaaac tgtgctatga aaggcaagca
781 taaagatgaa tgccacaact ttatcaaagt atttgttcca agaaacgatg agatggtttt
841 tgtttgtggt accaatgcat tcaatcccat gtgtagatac tacaggttga gtaccttaga
901 atatgatggg gaagaaatta gtggcctggc aagatgccca tttgatgcca gacaaaccaa
961 tgttgccctc tttgctgatg ggaagctgta ttctgccaca gtggctgact tcttggccag
1021 cgatgccgtt atttatcgaa gcatgggtga tggatctgcc cttcgcacaa taaaatatga
1081 ttccaaatgg ataaaagagc cacactttct tcatgccata gaatatggaa actatgtcta
1141 tttcttcttt cgagaaatcg ctgtcgaaca taataattta ggcaaggctg tgtattcccg
1201 cgtggcccgc atatgtaaaa acgacatggg tggttcccag cgggtcctgg agaaacactg
1261 gacttcattt ctaaaggctc ggctgaactg ttctgtccct ggagattcgt ttttctactt
1321 tgatgttctg cagtctatta cagacataat acaaatcaat ggcatcccca ctgtggtcgg
1381 ggtgtttacc acgcagctca atagcatccc tggttctgct gtctgtgcat ttagcatgga
1441 tgacattgaa aaagtattca aaggacggtt taaggaacag aaaactccag attctgtttg
1501 gacagcagtt cccgaagaca aagtgccaaa gccaaggcct ggctgttgtg caaaacacgg
1561 ccttgccgaa gcttataaaa cctccatcga tttcccggat gaaactctgt cattcatcaa
1621 atctcatccc ctgatggact ctgccgttcc acccattgcc gatgagccct ggttcacaaa
1681 gactcgggtc aggtacagac tgacggccat ctcagtggac cattcagccg gaccctacca
1741 gaactacaca gtcatctttg ttggctctga agctggcatg gtacttaaag ttctggcaaa
1801 gaccagtcct ttctctttga acgacagcgt attactggaa gagattgaag cctacaacca
1861 tgcaaagtgc agtgctgaga atgaggaaga caaaaaggtc atctcattac agttggataa
1921 agatcaccac gctttatatg tggcgttctc tagctgcatt atccgcatcc ccctcagtcg
1981 ctgtgagcgt tatggatcat gtaaaaagtc ttgtattgca tctcgtgacc cgtattgtgg
2041 ctggttaagc cagggatcct gtggtagagt gaccccaggg atgcttgctg aaggatatga
2101 acaagacaca gaattcggca acacagctca tctaggggac tgccatgaaa ttttgcctac
2161 ttcaactaca ccagattaca aaatatttgg cggtccaaca tctggtgtac gatgggaagt
2221 ccagtctgga gagtccaacc agatggtcca catgaatgtc ctcatcacct gtgtctttgc
2281 tgcttttgtt ttgggggcat tcattgcagg tgtggcagta tactgctatc gagacatgtt
2341 tgttcggaaa aacagaaaga tccataaaga tgcagagtcc gcccagtcat gcacagactc
2401 cagtggaagt tttgccaaac tgaatggtct ctttgacagc cctgtcaagg aataccaaca
2461 gaatattgat tctcctaaac tgtatagtaa cctgctaacc agtcggaaag agctaccacc
2521 caatggagat actaaatcca tggtaatgga ccatcgaggg caacctccag agttggctgc
2581 tcttcctact cctgagtcta cacccgtgct tcaccagaag accctgcagg ccatgaagag
2641 ccactcagaa aaggcccatg gccatggagc ttcaaggaaa gaaacccctc agttttttcc
2701 gtctagtccg ccacctcatt ccccattaag tcatgggcat atccccagtg ccattgttct
2761 tccaaatgct acccatgact acaacacgtc tttctcaaac tccaatgctc acaaagctga
2821 aaagaagctt caaaacattg atcaccctct cacaaagtca tccagtaaga gagatcaccg
2881 gcgttctgtt gattccagaa ataccctcaa tgatctcctg aagcatctga atgacccaaa
2941 tagtaacccc aaagccatca tgggagacat ccagatggca caccagaact taatgctgga
3001 tcccatggga tcgatgtctg aggtcccacc taaagtccct aaccgggagg catcgctata
3061 ctcccctcct tcaactctcc ccagaaatag cccaaccaag cgagtggatg tccccaccac
3121 tcctggagtc ccaatgactt ctctggaaag acaaagaggt tatcacaaaa attcctccca
3181 gaggcactct atatctgcta tgcctaaaaa cttaaactca ccaaatggtg ttttgttatc
3241 cagacagcct agtatgaacc gtggaggata tatgcccacc cccactgggg cgaaggtgga
3301 ctatattcag ggaacaccag tgagtgttca tctgcagcct tccctctcca gacagagcag
3361 ctacaccagt aatggcactc ttcctaggac gggactaaag aggacgccgt ccttaaaacc
3421 tgacgtgcca ccaaagcctt cctttgttcc tcaaacccca tctgtcagac cactgaacaa
3481 atacacatac taggcctcaa gtgtgctatt cccatgtggc tttatcctgt ccgtgttgtt
3541 gagaggatga tgttgtaagg gtaccttaaa acaagagact cgcttgtatt ttaagagaac
3601 caagtggcca aagaaactct ttctaacttt ggcaacatca gaacttgcca catgtagcta
3661 ctgcagcaag gcttctgtgt acttgcctga aaacaaagga aggtgctggt cattccattt
3721 cttttgtttg aagctaaaga gatgtgtagc tcacaggggc taccttacca gtataaagag
3781 ctgataacag tactcagaag aatctgtgaa caaatacttg aaaatgggtt caatgtagac
3841 tgccattatg tgtggtcttc ccattaaatg tgaacatttt aatatgtatg cattcacctt
3901 gcctcttgca caaatgtcaa aaaaaagatg gtaatatctc aaagaaatga acttgtagat
3961 taccaagcag tttgctaaaa attcaatctt tgacccaagc tgtagcattt ttttttcatg
4021 tgtggcatct ttttcatgcc accaacaaac ttgttgtgtg tgtgcgtgtg tgtgtgtgtg
4081 tgtgtgtgtg tgtgtgtgtg ttctgtaccc actaggattt gtttaggtgc ccattgcatc
4141 tttttgtgct atggagttgt ttacattaag catgaccgaa cgagagacaa tactatttcc
4201 cacaggagtc cattgggttc agctttgaaa gaggaataga atcgaggctc ctttgaccat
4261 caaaatgatg aactttactt atgtggtacc caatgccaga atgtaagagt tgcaagtgat
4321 tttgtgctgc tattcattaa aacttgtatt ccagtcttgc cagcttaagg agatcaagat
4381 attaagaggt atccttgatt tattttccag tattcagtag taaaattttc ctgtccactg
4441 tgaatcaaag cctgagtcac tctatttaac cttggacaca ctaataaggt tttattttga
4501 ttgtgttcgt ttcccccccc ccaatagtaa aatttctcct cctttaactc ctcctacccc
4561 ccaaggtaag aaacaaaaaa caaacaaaca aacaaaaata gaagacaaaa gaaagacata
4621 tgaaaggaat tgtaattggc ttaacagaaa cagtctgtaa aaacctaaca gtggtgcaat
4681 catgttgtct gtgttgtgtt atgtgagaat tttctcctaa gtcatgcagg taatgacaat
4741 atactgtaaa taccacatgt gagtttacct gaatctgtgc attttgtgcc ttattcatga
4801 gaatgataga agtactaaaa tctgtcaagt gttttcagta tagcacatta tttactgagt
4861 gccagttgta aatgtttttc aaccagcacc taaaaagact cttttcaaaa aatcacagaa
4921 acaacctagg acaattattt gttacataat ccgacctcat agcagcatta cattctttgc
4981 cgtgataaac attccactcc tgctttccta aggatgaaac agtgataatg tgaactcaaa
5041 tgaggtttcc tgggtaatgt gacacctgca gaaactatag agcgtcattt atacgtagtt
5101 tggcagaaac cacttacggc tgatgatgcg caaccctgct gactgtttca gttaatatgc
5161 tgcacaccac acacttgttt agtgaaccaa atctagaaag taccaaggca gaggtatgct
5221 cctgctgtaa tcaggcaaat gagttcaact ggatttcttt tgacaatact gttggtacct
5281 attacttggg ggaggacatg ttgcagaaga ccagatcatt tttatacaga atgtgaaata
5341 ctgatacagt tattcttttt tttaaagaac attgttttat aaagaacgtg atttccagtg
5401 atctctggaa gcgctaaagc taaaatttct gttcttgaaa cacttcagct ttgcaactaa
5461 aatattacag attaataata aattaaacca accaatgata aacactactc agtccaccaa
5521 caacaaacgt gtttgaattc accttaccaa tattaatccc agcgtgtgta aaacagaaca
5581 gtaactctat gtgaccccag ataacatttt gtaacattgt gcttccttgt agtttgtaat
5641 gtgagttcaa tcagtattta tgttgaaatt tctaacatta aatctagtct ctatcctgtt
5701 aatttaattt ttaaatgctt tatccatttg tgcaaaggta aacgcagatt gtatcttttt
5761 taatggtacg gcataaaaag taaccctcaa gtgaagtgtc tctatactgt tttatagagt
5821 actttaacat gaatagatac cttgtaaact tgtattgtgg atgtgtaaat aatatgtact
5881 ttgggttttt aacaccgcat gtaaagtcaa aataaaatat acaaatcatt ataaaaaaaa
5941 aaa
//