LOCUS AF389427 5886 bp mRNA linear HUM 17-SEP-2002
DEFINITION Homo sapiens semaphorin 6D isoform 2 (SEMA6D) mRNA, complete cds;
alternatively spliced.
ACCESSION AF389427
VERSION AF389427.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5886)
AUTHORS Qu,X., Wei,H., Zhai,Y., Que,H., Chen,Q., Tang,F., Wu,Y., Xing,G.,
Zhu,Y., Liu,S., Fan,M. and He,F.
TITLE Identification, characterization, and functional study of the two
novel human members of the semaphorin gene family
JOURNAL J. Biol. Chem. 277 (38), 35574-35585 (2002)
PUBMED 12110693
REFERENCE 2 (bases 1 to 5886)
AUTHORS Qu,X., Zhai,Y., Wei,H., Yu,Y., Tang,F. and He,F.
TITLE Homo sapiens semaphorin 6D isoform 2 (SEMA6D.2) mRNA, complete cds
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 5886)
AUTHORS Qu,X., Zhai,Y., Wei,H., Yu,Y., Tang,F. and He,F.
TITLE Direct Submission
JOURNAL Submitted (04-JUN-2001) Department of Genomics and Proteomics,
Beijing Institute of Radiation Medicine, Taiping Road 27, Beijing,
Beijing 100850, P.R. China
FEATURES Location/Qualifiers
source 1..5886
/db_xref="H-InvDB:HIT000078815"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="15"
/map="15q21.1"
/tissue_type="brain"
/dev_stage="adult"
gene 1..5886
/gene="SEMA6D"
CDS 440..3436
/gene="SEMA6D"
/note="axon guidance family member; belongs to class 6 of
semaphorin gene family; semaphorin 6D.2; alternative
spliced"
/codon_start=1
/product="semaphorin 6D isoform 2"
/protein_id="AAM69450.1"
/translation="MRVFLLCAYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVF
RGRPSGNESQHRLDFQLMLKIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQ
QDRENCAMKGKHKDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEI
SGLARCPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWI
KEPHFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTS
FLKARLNCSVPGDSFFYFDVLQSITDIIQINGIPTVVGVFTTQLNSIPGSAVCAFSMD
DIEKVFKGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSF
IKSHPLMDSAVPPIADEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLK
VLAKTSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCII
RIPLSRCERYGSCKKSCIASRDPYCGWLSQGSCGRVTPGMLAEGYEQDTEFGNTAHLG
DCHGVRWEVQSGESNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHK
DAESAQSCTDSSGSFAKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDTKSM
VMDHRGQPPELAALPTPESTPVLHQKTLQAMKSHSEKAHGHGASRKETPQFFPSSPPP
HSPLSHGHIPSAIVLPNATHDYNTSFSNSNAHKAEKKLQNIDHPLTKSSSKRDHRRSV
DSRNTLNDLLKHLNDPNSNPKAIMGDIQMAHQNLMLDPMGSMSEVPPKVPNREASLYS
PPSTLPRNSPTKRVDVPTTPGVPMTSLERQRGYHKNSSQRHSISAMPKNLNSPNGVLL
SRQPSMNRGGYMPTPTGAKVDYIQGTPVSVHLQPSLSRQSSYTSNGTLPRTGLKRTPS
LKPDVPPKPSFVPQTPSVRPLNKYTY"
BASE COUNT 1695 a 1347 c 1225 g 1619 t
ORIGIN
1 gcggccgctt cccaccgtcc ctctcccctt actggcagag cgcgctgcgg gcggactccc
61 gggcccggag cagcccaccg gccaccccac cgcccacccg gctcccggtg tctcctcccg
121 gccgctctac ccagcaactt tccgtgcttt gttccccgac tggaaatgct ttacggaagc
181 gtcttggaca gggtctccgc caggcgacaa gagctcggtg ctgagatgtg ttacgttctc
241 atctccccat caattatgga tggaaacaaa taaggaagag tcaattttgc tgagcccctt
301 ctccggcaac gagaggcgtt ctgcagccgg gagggagccg ccgctcgcgc cggcagccgc
361 tggcaggggc atggtgagga ggaaggtagc tcagtggcat ttctgagcag gggccaccct
421 gacttcacct tggcccacca tgagggtctt cctgctttgt gcctacatac tgctgctgat
481 ggtttcccag ttgagggcag tcagctttcc tgaagatgat gaacccctta atactgtcga
541 ctatcactat tcaaggcaat atccggtttt tagaggacgc ccttcaggca atgaatcgca
601 gcacaggctg gactttcagc tgatgttgaa aattcgagac acactttata ttgctggcag
661 ggatcaagtt tatacagtaa acttaaatga aatgcccaaa acagaagtaa tacccaacaa
721 gaaactgaca tggcgatcaa gacaacagga tcgagaaaac tgtgctatga aaggcaagca
781 taaagatgaa tgccacaact ttatcaaagt atttgttcca agaaacgatg agatggtttt
841 tgtttgtggt accaatgcat tcaatcccat gtgtagatac tacaggttga gtaccttaga
901 atatgatggg gaagaaatta gtggcctggc aagatgccca tttgatgcca gacaaaccaa
961 tgttgccctc tttgctgatg ggaagctgta ttctgccaca gtggctgact tcttggccag
1021 cgatgccgtt atttatcgaa gcatgggtga tggatctgcc cttcgcacaa taaaatatga
1081 ttccaaatgg ataaaagagc cacactttct tcatgccata gaatatggaa actatgtcta
1141 tttcttcttt cgagaaatcg ctgtcgaaca taataattta ggcaaggctg tgtattcccg
1201 cgtggcccgc atatgtaaaa acgacatggg tggttcccag cgggtcctgg agaaacactg
1261 gacttcattt ctaaaggctc ggctgaactg ttctgtccct ggagattcgt ttttctactt
1321 tgatgttctg cagtctatta cagacataat acaaatcaat ggcatcccca ctgtggtcgg
1381 ggtgtttacc acgcagctca atagcatccc tggttctgct gtctgtgcat ttagcatgga
1441 tgacattgaa aaagtattca aaggacggtt taaggaacag aaaactccag attctgtttg
1501 gacagcagtt cccgaagaca aagtgccaaa gccaaggcct ggctgttgtg caaaacacgg
1561 ccttgccgaa gcttataaaa cctccatcga tttcccggat gaaactctgt cattcatcaa
1621 atctcatccc ctgatggact ctgccgttcc acccattgcc gatgagccct ggttcacaaa
1681 gactcgggtc aggtacagac tgacggccat ctcagtggac cattcagccg gaccctacca
1741 gaactacaca gtcatctttg ttggctctga agctggcatg gtacttaaag ttctggcaaa
1801 gaccagtcct ttctctttga acgacagcgt attactggaa gagattgaag cctacaacca
1861 tgcaaagtgc agtgctgaga atgaggaaga caaaaaggtc atctcattac agttggataa
1921 agatcaccac gctttatatg tggcgttctc tagctgcatt atccgcatcc ccctcagtcg
1981 ctgtgagcgt tatggatcat gtaaaaagtc ttgtattgca tctcgtgacc cgtattgtgg
2041 ctggttaagc cagggatcct gtggtagagt gaccccaggg atgcttgctg aaggatatga
2101 acaagacaca gaattcggca acacagctca tctaggggac tgccatggtg tacgatggga
2161 agtccagtct ggagagtcca accagatggt ccacatgaat gtcctcatca cctgtgtctt
2221 tgctgctttt gttttggggg cattcattgc aggtgtggca gtatactgct atcgagacat
2281 gtttgttcgg aaaaacagaa agatccataa agatgcagag tccgcccagt catgcacaga
2341 ctccagtgga agttttgcca aactgaatgg tctctttgac agccctgtca aggaatacca
2401 acagaatatt gattctccta aactgtatag taacctgcta accagtcgga aagagctacc
2461 acccaatgga gatactaaat ccatggtaat ggaccatcga gggcaacctc cagagttggc
2521 tgctcttcct actcctgagt ctacacccgt gcttcaccag aagaccctgc aggccatgaa
2581 gagccactca gaaaaggccc atggccatgg agcttcaagg aaagaaaccc ctcagttttt
2641 tccgtctagt ccgccacctc attccccatt aagtcatggg catatcccca gtgccattgt
2701 tcttccaaat gctacccatg actacaacac gtctttctca aactccaatg ctcacaaagc
2761 tgaaaagaag cttcaaaaca ttgatcaccc tctcacaaag tcatccagta agagagatca
2821 ccggcgttct gttgattcca gaaataccct caatgatctc ctgaagcatc tgaatgaccc
2881 aaatagtaac cccaaagcca tcatgggaga catccagatg gcacaccaga acttaatgct
2941 ggatcccatg ggatcgatgt ctgaggtccc acctaaagtc cctaaccggg aggcatcgct
3001 atactcccct ccttcaactc tccccagaaa tagcccaacc aagcgagtgg atgtccccac
3061 cactcctgga gtcccaatga cttctctgga aagacaaaga ggttatcaca aaaattcctc
3121 ccagaggcac tctatatctg ctatgcctaa aaacttaaac tcaccaaatg gtgttttgtt
3181 atccagacag cctagtatga accgtggagg atatatgccc acccccactg gggcgaaggt
3241 ggactatatt cagggaacac cagtgagtgt tcatctgcag ccttccctct ccagacagag
3301 cagctacacc agtaatggca ctcttcctag gacgggacta aagaggacgc cgtccttaaa
3361 acctgacgtg ccaccaaagc cttcctttgt tcctcaaacc ccatctgtca gaccactgaa
3421 caaatacaca tactaggcct caagtgtgct attcccatgt ggctttatcc tgtccgtgtt
3481 gttgagagga tgatgttgta agggtacctt aaaacaagag actcgcttgt attttaagag
3541 aaccaagtgg ccaaagaaac tctttctaac tttggcaaca tcagaacttg ccacatgtag
3601 ctactgcagc aaggcttctg tgtacttgcc tgaaaacaaa ggaaggtgct ggtcattcca
3661 tttcttttgt ttgaagctaa agagatgtgt agctcacagg ggctacctta ccagtataaa
3721 gagctgataa cagtactcag aagaatctgt gaacaaatac ttgaaaatgg gttcaatgta
3781 gactgccatt atgtgtggtc ttcccattaa atgtgaacat tttaatatgt atgcattcac
3841 cttgcctctt gcacaaatgt caaaaaaaag atggtaatat ctcaaagaaa tgaacttgta
3901 gattaccaag cagtttgcta aaaattcaat ctttgaccca agctgtagca tttttttttc
3961 atgtgtggca tctttttcat gccaccaaca aacttgttgt gtgtgtgcgt gtgtgtgtgt
4021 gtgtgtgtgt gtgtgtgtgt gtgttctgta cccactagga tttgtttagg tgcccattgc
4081 atctttttgt gctatggagt tgtttacatt aagcatgacc gaacgagaga caatactatt
4141 tcccacagga gtccattggg ttcagctttg aaagaggaat agaatcgagg ctcctttgac
4201 catcaaaatg atgaacttta cttatgtggt acccaatgcc agaatgtaag agttgcaagt
4261 gattttgtgc tgctattcat taaaacttgt attccagtct tgccagctta aggagatcaa
4321 gatattaaga ggtatccttg atttattttc cagtattcag tagtaaaatt ttcctgtcca
4381 ctgtgaatca aagcctgagt cactctattt aaccttggac acactaataa ggttttattt
4441 tgattgtgtt cgtttccccc cccccaatag taaaatttct cctcctttaa ctcctcctac
4501 cccccaaggt aagaaacaaa aaacaaacaa acaaacaaaa atagaagaca aaagaaagac
4561 atatgaaagg aattgtaatt ggcttaacag aaacagtctg taaaaaccta acagtggtgc
4621 aatcatgttg tctgtgttgt gttatgtgag aattttctcc taagtcatgc aggtaatgac
4681 aatatactgt aaataccaca tgtgagttta cctgaatctg tgcattttgt gccttattca
4741 tgagaatgat agaagtacta aaatctgtca agtgttttca gtatagcaca ttatttactg
4801 agtgccagtt gtaaatgttt ttcaaccagc acctaaaaag actcttttca aaaaatcaca
4861 gaaacaacct aggacaatta tttgttacat aatccgacct catagcagca ttacattctt
4921 tgccgtgata aacattccac tcctgctttc ctaaggatga aacagtgata atgtgaactc
4981 aaatgaggtt tcctgggtaa tgtgacacct gcagaaacta tagagcgtca tttatacgta
5041 gtttggcaga aaccacttac ggctgatgat gcgcaaccct gctgactgtt tcagttaata
5101 tgctgcacac cacacacttg tttagtgaac caaatctaga aagtaccaag gcagaggtat
5161 gctcctgctg taatcaggca aatgagttca actggatttc ttttgacaat actgttggta
5221 cctattactt gggggaggac atgttgcaga agaccagatc atttttatac agaatgtgaa
5281 atactgatac agttattctt ttttttaaag aacattgttt tataaagaac gtgatttcca
5341 gtgatctctg gaagcgctaa agctaaaatt tctgttcttg aaacacttca gctttgcaac
5401 taaaatatta cagattaata ataaattaaa ccaaccaatg ataaacacta ctcagtccac
5461 caacaacaaa cgtgtttgaa ttcaccttac caatattaat cccagcgtgt gtaaaacaga
5521 acagtaactc tatgtgaccc cagataacat tttgtaacat tgtgcttcct tgtagtttgt
5581 aatgtgagtt caatcagtat ttatgttgaa atttctaaca ttaaatctag tctctatcct
5641 gttaatttaa tttttaaatg ctttatccat ttgtgcaaag gtaaacgcag attgtatctt
5701 ttttaatggt acggcataaa aagtaaccct caagtgaagt gtctctatac tgttttatag
5761 agtactttaa catgaataga taccttgtaa acttgtattg tggatgtgta aataatatgt
5821 actttgggtt tttaacaccg catgtaaagt caaaataaaa tatacaaatc attataaaaa
5881 aaaaaa
//