LOCUS AF387507 3421 bp mRNA linear HUM 01-JUL-2001
DEFINITION Homo sapiens PIWI protein mRNA, complete cds.
ACCESSION AF387507
VERSION AF387507.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3421)
AUTHORS Sha,J.H.
TITLE Cloning and identification of human piwi protein related to testis
development
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 3421)
AUTHORS Sha,J.H., Li,J.M. and Zhou,Z.M.
TITLE Direct Submission
JOURNAL Submitted (30-MAY-2001) Key Lab of Reproductive Medicine, Nanjing
Medical University, 140 Han Zhong Road, Nanjing Medical University,
Jiangsu 210029, China
FEATURES Location/Qualifiers
source 1..3421
/db_xref="H-InvDB:HIT000078759"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="testis"
/dev_stage="adult"
CDS 64..2649
/note="higher expression in adult testis than 6 month old
embryo testis"
/codon_start=1
/product="PIWI protein"
/protein_id="AAK69348.1"
/translation="MTGRARARARGRARGQETAQLVGSTASQQPGYIQPRPQPPPAEG
ELFGRGRQRGTAGGTAKSQGLQISAGFQELSLAERGGRRRDFHDLGVNTRQNLDHVKE
SKTGSSGIIVRLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGKC
HAFDGTILFLPKRLQQKVTEVFSKTRNGEDVRITITLTNELPPTSPTCLQFYNIIFRR
LLKIMNLQQIGRNYYNPNDPIDIPSHRLVIWPGFTTSILQYENSIMLCTDVSHKVLRS
ETVLDFMFNFYHQTEEHKFQEQVSKELIGLVVLTKYNNKTYRVDDIDWDQNPKSTFKK
ADGSEVSFLEYYRKQYNQEITDLKQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGL
TDKMRNDFNVMKDLAVHTRLTPEQRQREVGRLIDYIHKNDNVQRELRDWGLSFDSNLL
SFSGRILQTEKIHQGGKTFDYNPQFADWSKETRGAPLISVKPLDNWLLIYTRRNYEAA
NSLIQNLFKVTPAMGMQMRKAIMIEVDDRTEAYLRVLQQKVTADTQIVVCLLSSNRKD
KYDAIKKYLCTDCPTPSQCVVARTLGKQQTVMAIATKIALQMNCKMGGELWRVDIPLK
LVMIVGIDCYHDMTAGRRSIAGFVASINEGMTRWFSRCIFQDRGQELVDGLKVCLQAA
LRAWNSCNEYMPSRIIVYRDGVGDGQLKTLVNYEVPQFLDCLKSIGRGYNPRLTVIVV
KKRVNTRFFAQSGGRLQNPLPGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIY
DNSGLKPDHIQRLTYKLCHIYYNWPGVIRVPAPCQYAHKLAFLVGQSIHREPNLSLSN
RLYYL"
regulatory 3354..3359
/regulatory_class="polyA_signal_sequence"
BASE COUNT 1071 a 661 c 767 g 922 t
ORIGIN
1 gggggggctg aggtgcaagg accaggacta gggcgagggc agcggtccaa gaaatagaaa
61 acaatgactg ggagagcccg agccagagcc agaggaaggg cccgcggtca ggagacagcg
121 cagctggtgg gctccactgc cagtcagcaa cctggttata ttcagcctag gcctcagccg
181 ccaccagcag agggggaatt atttggccgt ggacggcaga gaggaacagc aggaggaaca
241 gccaagtcac aaggactcca gatatctgct ggatttcagg agttatcgtt agcagagaga
301 ggaggtcgtc gtagagattt tcatgatctt ggtgtgaata caaggcagaa cctagaccat
361 gttaaagaat caaaaacagg ttcttcaggc attatagtaa ggttaagcac taaccatttc
421 cggctgacat cccgtcccca gtgggcctta tatcagtatc acattgacta taacccactg
481 atggaagcca gaagactccg ttcagctctt ctttttcaac acgaagatct aattggaaag
541 tgccatgctt ttgatggaac gatattattt ttacctaaaa gactacagca aaaggttact
601 gaagttttta gtaagacccg gaatggagag gatgtgagga taacgatcac tttaacaaat
661 gaacttccac ctacatcacc aacttgtttg cagttctata atattatttt caggaggctt
721 ttgaaaatca tgaatttgca acaaattgga cgaaattatt ataacccaaa tgacccaatt
781 gatattccaa gtcacaggtt ggtgatttgg cctggcttca ctacttccat ccttcagtat
841 gaaaacagca tcatgctctg cactgacgtt agccataaag tccttcgaag tgagactgtt
901 ttggatttca tgttcaactt ttatcatcag acagaagaac ataaatttca agaacaagtt
961 tccaaagaac taataggttt agttgttctt accaagtata acaataagac atacagagtg
1021 gatgatattg actgggacca gaatcccaag agcaccttta agaaagccga cggctctgaa
1081 gtcagcttct tagaatacta caggaagcaa tacaaccaag agatcaccga cttgaagcag
1141 cctgtcttgg tcagccagcc caagagaagg cggggccctg gggggacact gccagggcct
1201 gccatgctca ttcctgagct ctgctatctt acaggtctaa ctgataaaat gcgtaatgat
1261 tttaacgtga tgaaagactt agccgttcat acaagactaa ctccagagca aaggcagcgt
1321 gaagtgggac gactcattga ttacattcat aaaaacgata atgttcaaag ggagcttcga
1381 gactggggtt tgagctttga ttccaactta ctgtccttct caggaagaat tttgcaaaca
1441 gaaaagattc accaaggtgg aaaaacattt gattacaatc cacaatttgc agattggtcc
1501 aaagaaacaa gaggtgcacc attaattagt gttaagccac tagataactg gctgttgatc
1561 tatacgcgaa gaaattatga agcagccaat tcattgatac aaaatctatt taaagttaca
1621 ccagccatgg gcatgcaaat gagaaaagca ataatgattg aagtggatga cagaactgaa
1681 gcctacttaa gagtcttaca gcaaaaggtc acagcagaca cccagatagt tgtctgtctg
1741 ttgtcaagta atcggaagga caaatacgat gctattaaaa aatacctgtg tacagattgc
1801 cctaccccaa gtcagtgtgt ggtggcccga accttaggca aacagcaaac tgtcatggcc
1861 attgctacaa agattgccct acagatgaac tgcaagatgg gaggagagct ctggagggtg
1921 gacatccccc tgaagctcgt gatgatcgtt ggcatcgatt gttaccatga catgacagct
1981 gggcggaggt caatcgcagg atttgttgcc agcatcaatg aagggatgac ccgctggttc
2041 tcacgctgca tatttcagga tagaggacag gagctggtag atgggctcaa agtctgcctg
2101 caagcggctc tgagggcttg gaatagctgc aatgagtaca tgcccagccg gatcatcgtg
2161 taccgcgatg gcgtaggaga cggccagctg aaaacactgg tgaactacga agtgccacag
2221 tttttggatt gtctaaaatc cattggtaga ggttacaacc ctagactaac ggtaattgtg
2281 gtgaagaaaa gagtgaacac cagatttttt gctcagtctg gaggaagact tcagaatcca
2341 cttcctggaa cagttattga tgtagaggtt accagaccag aatggtatga cttttttatc
2401 gtgagccagg ctgtgagaag tggtagtgtt tctcccacac attacaatgt catctatgac
2461 aacagcggcc tgaagccaga ccacatacag cgcttgacct acaagctgtg ccacatctat
2521 tacaactggc caggtgtcat tcgtgttcct gctccttgcc agtacgccca caagctggct
2581 tttcttgttg gccagagtat tcacagagag ccaaatctgt cactgtcaaa ccgcctttac
2641 tacctctaac ctgcagaaga cgatgcagcc gcttttcttt ttgaaatgac tttgggattt
2701 ttttaagctt ttatttactt tttttttaac tgttatcttt ctggatgaaa cttgggaagg
2761 ggattaggag atctagcatt ttatttctag cattgctatt caccggcttc cttattttat
2821 atgtaaaaat taagatttta tattttatct tcttgtttct catagatatt ttgtgagcat
2881 ttttttgttt attttgaaga aatgtggata agatacttgg tagtatgaaa cagactctct
2941 gagagtattt gaaatgtgtt tggagattta cttaaacgta ctttcaggag tgagcaagtc
3001 ctacttataa acctatatta actttatttt tgagatacct gttttgaatt taaaggagat
3061 aagaggcgta aagtaggatg ctcactacaa ccataggtgg ggtttcagct catatcttaa
3121 agataaaagg tactattata taacctatac acaagataca ggagaaaata tgcttgattt
3181 ttatttggca ggggggctag gttgtatggg agtaaaaaaa aacattgaaa atttttaaat
3241 tgtccaaaga aacattttaa gactctttaa caaaaaaggc catgagtaaa tctctatatt
3301 aacattacta tttattttgt tttggaactg ggacatgatt ctatttgtta taaaataaaa
3361 ttgatgtgat tgtcacctta aaaaaaaaaa aaaccaaaaa aaaaaaaaaa aaaaaaaaaa
3421 a
//