LOCUS AF385399 2402 bp mRNA linear HUM 07-MAY-2002
DEFINITION Homo sapiens potassium channel TREK2 splice variant b mRNA,
complete cds.
ACCESSION AF385399
VERSION AF385399.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2402)
AUTHORS Gu,W., Schlichthorl,G., Hirsch,J.R., Engels,H., Karschin,C.,
Karschin,A., Derst,C., Steinlein,O.K. and Daut,J.
TITLE Expression pattern and functional characteristics of two novel
splice variants of the two-pore-domain potassium channel TREK-2
JOURNAL J. Physiol. (Lond.) 539 (Pt 3), 657-668 (2002)
PUBMED 11897838
REFERENCE 2 (bases 1 to 2402)
AUTHORS Gu,W. and Steinlein,O.K.
TITLE Direct Submission
JOURNAL Submitted (25-MAY-2001) Lab EEG, Inst. of Humangenetics,
Wilhelmstr. 31, Bonn 53111, Germany
FEATURES Location/Qualifiers
source 1..2402
/db_xref="H-InvDB:HIT000078730"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="14"
/map="14q31-q32"
CDS 124..1755
/note="KCNK10"
/codon_start=1
/product="potassium channel TREK2 splice variant b"
/protein_id="AAL95705.1"
/translation="MEDGFKGDRTEGCRSDSVAVPAAAPVCQPKSATNGQPPAPAPTP
TPRLSISSRATVVARMEGTSQGGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPF
ESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLG
SAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKS
IARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVV
VTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKT
KEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAH
SLDMLSPEKRSVFAALDTGRFKASSQESINNRPNNLRLKGPEQLNKHGQGASEDNIIN
KFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYSLDEEKKEEETEKMCNSDNSSTAM
LTDCIQQHAELENGMIPTDTKDREPGNNSLLEDRN"
BASE COUNT 617 a 569 c 667 g 549 t
ORIGIN
1 gcaaggcatg gagcctgcac tttactctga atgttggtgg cgccttcaga gcattgttag
61 caaggggtcc atgtgatcac actgacactt gagagagtga cacaccatgt acatggttgg
121 tatatggagg atggatttaa gggggacagg actgaaggct gtcgcagtga ttcagtggcc
181 gttcccgcag cagcaccggt gtgccagccc aagagcgcca ctaacgggca acccccggct
241 ccggctccga ctccaactcc gcgcctgtcc atttcctccc gagccacagt ggtagccagg
301 atggaaggca cctcccaagg gggcttgcag accgtcatga agtggaagac ggtggttgcc
361 atctttgtgg ttgtggtggt ctaccttgtc actggcggtc ttgtcttccg ggcattggag
421 cagccctttg agagcagcca gaagaatacc atcgccttgg agaaggcgga attcctgcgg
481 gatcatgtct gtgtgagccc ccaggagctg gagacgttga tccagcatgc tcttgatgct
541 gacaatgcgg gagtcagtcc aataggaaac tcttccaaca acagcagcca ctgggacctc
601 ggcagtgcct ttttctttgc tggaactgtc attacgacca tagggtatgg gaatattgct
661 ccgagcactg aaggaggcaa aatcttttgt attttatatg ccatctttgg aattccactc
721 tttggtttct tattggctgg aattggagac caacttggaa ccatctttgg gaaaagcatt
781 gcaagagtgg agaaggtctt tcgaaaaaag caagtgagtc agaccaagat ccgggtcatc
841 tcaaccatcc tgttcatctt ggccggctgc attgtgtttg tgacgatccc tgctgtcatc
901 tttaagtaca tcgagggctg gacggccttg gagtccattt actttgtggt ggtcactctg
961 accacggtgg gctttggtga ttttgtggca gggggaaacg ctggcatcaa ttatcgggag
1021 tggtataagc ccctagtgtg gttttggatc cttgttggcc ttgcctactt tgcagctgtc
1081 ctcagtatga tcggagattg gctacgggtt ctgtccaaaa agacaaaaga agaggtgggt
1141 gaaatcaagg cccatgcggc agagtggaag gccaatgtca cggctgagtt ccgggagaca
1201 cggcgaaggc tcagcgtgga gatccacgat aagctgcagc gggcggccac catccgcagc
1261 atggagcgcc ggcggctggg cctggaccag cgggcccact cactggacat gctgtccccc
1321 gagaagcgct ctgtctttgc tgccctggac accggccgct tcaaggcctc atcccaggag
1381 agcatcaaca accggcccaa caacctgcgc ctgaaggggc cggagcagct gaacaagcat
1441 gggcagggtg cgtccgagga caacatcatc aacaagttcg ggtccacctc cagactcacc
1501 aagaggaaaa acaaggacct caaaaagacc ttgcccgagg acgttcagaa aatctacaag
1561 accttccgga attactccct ggacgaggag aagaaagagg aggagacgga aaagatgtgt
1621 aactcagaca actccagcac agccatgctg acggactgta tccagcagca cgctgagttg
1681 gagaacggaa tgatacccac ggacaccaaa gaccgggagc cggggaacaa ctcattactt
1741 gaagacagaa actaaatgtg aaggacattg gtcttggact gagcgttgtg tgtgtgtgtg
1801 tgtgtgtttt taatattcac actgagacat gtgccttaaa cagacttttt agtccaaaat
1861 tacatagcat tgaagaatat atttcactgt gccataaaca actgaaagct tgctctgcca
1921 aaaggaatca gagaacaaga acttcatttc agatagcaaa cgcaggacac accaagagtg
1981 tccgtgcacg tagccggttc tggccgtaca tgttaagggc atttcagtgg cagtgctgta
2041 cccctgggca gtgctacctg ggcacacacg tagacaaggg cagctattcc ttagaccagc
2101 ctcctgaaag aaacaggtgt gtctttttag tggagtcgta gtaatatgtg cacacacaga
2161 aggggacctg attgggtggg agctggttat gtgtaactag cgttggagtt gacattttgg
2221 catgtgctct gagcttgaat tttgatacca accattcagt gcatcatacc tagtctttct
2281 atgctccaaa tgaatgtctg tggggacctg agagcacctg gaatttgttg gaagcagatc
2341 agagcacacg tacgaaaagg tgcaattgct tttctcatga caaaaaaaaa aaaaaaaaaa
2401 aa
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