LOCUS AF384048 2659 bp DNA linear HUM 23-OCT-2001
DEFINITION Homo sapiens interferon kappa precursor gene, complete cds.
ACCESSION AF384048
VERSION AF384048.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2659)
AUTHORS LaFleur,D.W., Nardelli,B., Tsareva,T., Mather,D., Feng,P.,
Semenuk,M., Taylor,K., Buergin,M., Chinchilla,D., Roshke,V.,
Chen,G., Ruben,S.M., Pitha,P.M., Coleman,T.A. and Moore,P.A.
TITLE Interferon-kappa, a novel type I interferon expressed in human
keratinocytes
JOURNAL J. Biol. Chem. 276 (43), 39765-39771 (2001)
PUBMED 11514542
REFERENCE 2 (bases 1 to 2659)
AUTHORS LaFleur,D.W. and Moore,P.A.
TITLE Direct Submission
JOURNAL Submitted (22-MAY-2001) Preclinical Discovery, Human Genome
Sciences, Inc., 9410 Key West Avenue, Rockville, MD 20850, USA
FEATURES Location/Qualifiers
source 1..2659
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/chromosome="9"
/map="9p21.2"
regulatory 424..428
/regulatory_class="TATA_box"
mRNA join(478..1125,2169..2659)
/product="interferon kappa precursor"
CDS 501..1124
/codon_start=1
/product="interferon kappa precursor"
/protein_id="AAK63835.1"
/translation="MSTKPDMIQKCLWLEILMGIFIAGTLSLDCNLLNVHLRRVTWQN
LRHLSSMSNSFPVECLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFSQHT
FKYWKERHLKQIQIGLDQQAEYLNQCLEEDENENEDMKEMKENEMKPSEARVPQLSSL
ELRRYFHRIDNFLKEKKYSDCAWEIVRVEIRRCLYYFYKFTALFRRK"
regulatory 2631..2636
/regulatory_class="polyA_signal_sequence"
BASE COUNT 837 a 523 c 514 g 785 t
ORIGIN
1 cacagtcatt tggtcaatgt ctatgattaa ctcaatgaga caggatgttt ggctatagca
61 ccaggtacaa aaaatatatt ttcatgaagg atcactccct cttatgtaat agatttgggt
121 gagtgagtga gtgagtgagt gcatggactc acagcttttg gctttctgaa ataccctgca
181 tcagtcttgt tatgatgatt ccttagtgct gggatggatc atccaggcat ttaaggtaac
241 acgatggtaa ttctttgctc atttttcagg gaaaaaaaaa agttatcact tccaaagtcg
301 gcatagtcac ccgaagtaaa aaaaaaaaaa aaaaagcctc agaggcaaag gaaaggggcc
361 gcaaccttgg ttaactgtga aatgacgaat gagaaaactc ctcctgctgg agatattcag
421 gtatataaag gcacatgaag gaaaactcaa aacatcattg tcatatacac atcttctgga
481 ttttttagct tgcaaaaaaa atgagcacca aacctgatat gattcaaaag tgtttgtggc
541 ttgagatcct tatgggtata ttcattgctg gcaccctatc cctggactgt aacttactga
601 acgttcacct gagaagagtc acctggcaaa atctgagaca tctgagtagt atgagcaatt
661 catttcctgt agaatgtcta cgagaaaaca tagcttttga gttgccccaa gagtttctgc
721 aatacaccca acctatgaag agggacatca agaaggcctt ctatgaaatg tccctacagg
781 ccttcaacat cttcagccaa cacaccttca aatattggaa agagagacac ctcaaacaaa
841 tccaaatagg acttgatcag caagcagagt acctgaacca atgcttggag gaagacgaga
901 atgaaaatga agacatgaaa gaaatgaaag agaatgagat gaaaccctca gaagccaggg
961 tcccccagct gagcagcctg gaactgagga gatatttcca caggatagac aatttcctga
1021 aagaaaagaa atacagtgac tgtgcctggg agattgtccg agtggaaatc agaagatgtt
1081 tgtattactt ttacaaattt acagctctat tcaggaggaa ataaggtata tttttggaat
1141 taaaattcct tttccctccg aaatctcttt ctccttctcc tcctccatct tctttttaag
1201 gattgttgtg ctgtcctgta agcctgtcct cagttggact ggtagcctcg gaacatcagg
1261 gacactcacc tctctaagga gaggtagtgc caaccatcct cagggtgacc aagagtctcc
1321 ttagaaagtc tttaagacat ttttaaagga ataagattcc ctctccgtct tcttctattc
1381 tctcttcctc ttttctgtgg ccattttgaa agagctttgc tatatatacc acctgtggac
1441 ttcaccaaga caatggctag aggataggga gcagagaatg ttgcaaagtg gtaacatttc
1501 aatgacttaa ctgttttgct gccaaggttg cttatcctat gaaaattcag cacattaaaa
1561 gagcttatac atgctcccta gagtcaatac tcttgcattt tccccctcct gctcgggggg
1621 aaaaaggttg acatttctgg cccatttcct tctcagcttg gtttgtttga attgatgctt
1681 gtggaatggt atttcattac tttaagagtg aagatccata gtgaaattgg atggatggtt
1741 gaattagacg accattaagc tttcatttaa cctttgagag tctgtgattc taatgtagca
1801 cactcttcat tcctgatgta tattgtttga ttcctacatc taaaggcatg gaaaatgctg
1861 tgaaagtatg gtacagaatc tgtcttttac tgtttttcat gtgcctgaaa taaaatgtcc
1921 agagtcataa tatggaacaa ttttacatta gattttccta gttagaagac tacattctgt
1981 gagttaattt aactagctat tccaataata catagtactt taatatcttt tatcttttta
2041 aaagttactt tgcagccaga ctacctagat tatttacttt tctagcacgg cccttcatct
2101 atattaattc accacctagc tgacatggat tttctcttcc tctcgcacct ctatctaccc
2161 catttcagaa tcatctacct tcaagcaaga attaacagag attgtggcta cgcaaatgca
2221 ccaaaaaagg gtgaaatata tctgaaatgt acctggttct gcccttggaa gccacttcct
2281 gctcatgcca ctaacagcat gctgccaaac tgttcagatt caagattatt ccaagcgcag
2341 ggcccaaatg ttatagccaa agaaagtctt atgataaaag tgaggcaaat ttcagccaag
2401 aagttagaag agatgtttaa aagaacaaga acaaattgtg gatcatggta tatgcaggct
2461 atcagcagaa ggatcagaca ataaaatgag ttagtgcaaa ccatttagta aaaataacta
2521 tcagcagagt tgttccagat taaaaatagt actacaagct tgtaaaggag ttaggacatg
2581 caagctactg agcataaaat atatacttgc tatttttcat gactttctct aataaagtct
2641 ttgctgttct ctctaataa
//