LOCUS AF380181 8395 bp mRNA linear HUM 22-NOV-2001
DEFINITION Homo sapiens SON DNA binding protein isoform C (SON) mRNA, complete
cds, alternatively spliced.
ACCESSION AF380181
VERSION AF380181.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 8395)
AUTHORS Reymond,A., Friedli,M., Henrichsen,C.N., Chapot,F., Deutsch,S.,
Ucla,C., Rossier,C., Lyle,R., Guipponi,M. and Antonarakis,S.E.
TITLE From PREDs and open reading frames to cDNA isolation: revisiting
the human chromosome 21 transcription map
JOURNAL Genomics 78 (1-2), 46-54 (2001)
PUBMED 11707072
REFERENCE 2 (bases 1 to 8395)
AUTHORS Reymond,A., Deutsch,S. and Antonarakis,S.E.
TITLE Direct Submission
JOURNAL Submitted (12-MAY-2001) Division of Medical Genetics, University of
Geneva Medical School, CMU, 1, Av. Michel Servet, Geneva, GE 1211,
Switzerland
FEATURES Location/Qualifiers
source 1..8395
/db_xref="H-InvDB:HIT000078629"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="21"
/map="21q22.11"
gene 1..8395
/gene="SON"
CDS 30..7007
/gene="SON"
/note="alternatively spliced"
/codon_start=1
/product="SON DNA binding protein isoform C"
/protein_id="AAL34499.1"
/translation="MATNIEQIFRSFVVSKFREIQQELSSGRNEGQLNGETNTPIEGN
QAGDAAASARSLPNEEIVQKIEEVLSGVLDTELRYKPDLKEGSRKSRCVSVQTDPTDE
IPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDSFLKFDS
EPSAVALELPTRAFGPSETNESPAVVLEPPVVSMEVSEPHILETLKPATKTAELSVVS
TSVISEQSEQSVAVMPEPSMTKILDSFAAAPVPTTTLVLKSSEPVVTMSVEYQMKSVL
KSVESTSPEPSKIMLVEPPVAKVLEPSETLVVSSETPTEVYPEPSTSTTMDFPESSAI
EALRLPEQPVDVPSEIADSSMTRPQELPELPKTTALELQESSVASAMELPGPPATSMP
ELQGPPVTPVLELPGPSATPVPELPGPLSTPVPELPGPPATAVPELPGPSVTPVPQLS
QELPGLPAPSMGLEPPQEVPEPSVMAQELPGLPLVTAAVELPEQPAVTVAMELTEQPV
TTTELEQPVGMTTVEHPGHPEVTTATGLLGQPEATMVLELPGQPVATTALELPGQPSV
TGVPELPGLPSATRALELSGQPVATGALELPGPLMAAGALEFSGQSGAAGALELLGQP
LATGVLELPGQPGAPELPGQPVATVALEISVQSVVTTSELSTMTVSQSLEVPSTTALE
SYNTVAQELPTTLVGETSVTVGVDPLMAPESHILASNTMETHILASNTMDSQMLASNT
MDSQMLASNTMDSQMLASSTMDSQMLATSSMDSQMLATSSMDSQMLATSTMDSQMLAT
SSMDSQMLATSSMDSQMLATSSMDSQMLATSSMDSQMLATSTMDSQMLATSTMDSQML
ATSSMDSQMLASGTMDSQMLASGTMDAQMLASGTMDAQMLASSTQDSAMLGSKSPDPY
RLAQDPYRLAQDPYRLGHDPYRLGHDAYRLGQDPYRLGHDPYRLTPDPYRMSPRPYRI
APRSYRIAPRPYRLAPRPLMLASRRSMMMSYAAERSMMSSYERSMMSYERSMMSPMAE
RSMMSAYERSMMSAYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMADRSMMSMGA
DRSMMSSYSAADRSMMSSYSAADRSMMSSYTADRSMMSMAADSYTDSYTDTYTEAYMV
PPLPPEEPPTMPPLPPEEPPMTPPLPPEEPPEGPALPTEQSALTAENTWPTEVPSLPS
EESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPEPESSITLT
PVESAVVAEEHEVVPERPVTCMVSETPAMSAEPTVLASEPPVMSETAETFDSMRASGH
VASEVSTSLLVPAVTTPVLAESILEPPAMAAPESSAMAVLESSAVTVLESSTVTVLES
STVTVLEPSVVTVPEPPVVAEPDYVTIPVPVVSALEPSVPVLEPAVSVLQPSMIVSEP
SVSVQESTVTVSEPAVTVSEQTQVIPTEVAIESTPMILESSIMSSHVMKGINLSSGDQ
NLAPEIGMQEIALHSGEEPHAEEHLKGDFYESEHGINIDLNINNHLIAKEMEHNTVCA
AGTSPVGEIGEEKILPTSETKQRTVLDTYPGVSEADAGETLSSTGPFALEPDATGTSK
GIEFTTASTLSLVNKYDVDLSLTTQDTEHDMVISTSPSGGSEADIEGPLPAKDIHLDL
PSNNNLVSKDTEEPLPVKESDQTLAALLSPKESSGGEKEVPPPPKETLPDSGFSANIE
DINEADLVRPLLPKDMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSS
EEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSE
SRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSK
SRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSR
TPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVR
LRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRLTDLDKAQLLEIAKANAAAMCAKAG
VPLPPNLKPAPPPTIEEKVAKKSGGATIEELTEKCKQIAQSKEDDDVIVNKPHVSDEE
EEEPPFYHHPFKLSEPKPIFFNLNIAAAKPTPPKSQVTLTKEFPVSSGSQHRKKEADS
VYGEWVPVEKNGEENKDDDNVFSSNLPSEPVDISTAMSERALAQKRLSENAFDLEAMS
MLNRAQERIDAWAQLNSIPGQFTGSTGVQVLTQEQLANTGAQAWIKKGQILVAVFLPR
SVPAVLFTTLLLPRPRISS"
BASE COUNT 2396 a 1930 c 2014 g 2055 t
ORIGIN
1 ggaggagttg agagaacgga gcggacgcca tggcgaccaa catcgagcag atttttaggt
61 ctttcgtggt cagtaaattc cgggaaattc aacaggagct ttccagtgga aggaatgaag
121 gccagctgaa tggtgaaaca aatacaccca ttgaaggaaa ccaggcgggt gatgcagctg
181 cctctgccag gagtctacca aatgaagaaa tagtgcagaa gatagaggaa gtactttctg
241 gggtcttaga tacagaacta cgatataagc cagacttgaa agagggctcc agaaaaagta
301 gatgcgtatc tgtacaaaca gatcctactg atgaaattcc cactaaaaag tcaaagaagc
361 ataaaaagca caaaaacaaa aagaagaaaa agaagaaaga aaaggaaaaa aaatataaaa
421 gacagccaga agaatctgag tcaaagacga aatctcatga tgatgggaac atagatttag
481 aatctgattc ctttttaaag tttgattctg aaccttcagc tgtggcgctg gagcttccta
541 caagagcatt tggcccatct gagaccaatg aatcccctgc agttgtgcta gaacctcctg
601 tagtatcaat ggaggtatca gagccacaca tcttagaaac tctgaagcca gctacaaaaa
661 ctgcagaact gtcagttgta tctacatcag taatctcaga gcagtcagag cagtctgtgg
721 cagtaatgcc agaaccatcc atgacaaaga ttctggattc ctttgcagca gcaccagtgc
781 ctactacaac actggtgttg aagtcatctg agccagttgt aacaatgtca gtggagtatc
841 agatgaagtc tgtgctgaaa tctgtggaga gcacatctcc agagccatca aagatcatgt
901 tggtagagcc cccagtagca aaagtgttag agccttcaga aacccttgtg gtatcatcag
961 agacacctac tgaggtgtac cctgagccaa gcacatcaac aacaatggat tttccagagt
1021 catctgcaat tgaagcgcta agattgccag agcagcctgt agacgtacca tcggagattg
1081 cagattcatc catgacaaga ccgcaggagt tgccggagct gcctaagacc acagcgttgg
1141 agctgcagga gtcgtcggtg gcctcagcga tggagttgcc ggggccacct gcgacctcca
1201 tgccggagtt gcaggggccc cctgtgactc cagtgctgga gttacctggg ccctctgcta
1261 ccccggtgcc agagttgcca gggccccttt ctaccccagt gcctgagttg ccagggcccc
1321 ctgcgacagc agtgcctgag ttgccagggc cctctgtgac accagtgcca cagttgtcgc
1381 aggaattgcc agggcttcca gcaccatcca tggggttgga gccaccacag gaggtaccag
1441 agccatctgt gatggcacag gagttgccag ggctgccttt ggtgacagca gcagtagagt
1501 tgccagagca gcctgcggta acagtagcaa tggagttgac cgaacaacct gtgacgacga
1561 cagagttgga gcagcctgtg gggatgacaa cggtggaaca tcctgggcat cctgaggtga
1621 caacggcaac agggttgctg gggcagcctg aggcaacgat ggtgctggag ttgccaggac
1681 agccagtggc aacgacagcg ctggagttgc cggggcagcc ttcggtgact ggggtgccag
1741 agttgccagg gctgccttcg gcaactaggg cactggagtt gtcggggcag cctgtggcaa
1801 ctggggcact agagttgcct gggccgctca tggcagctgg ggcactggag ttctcggggc
1861 agtctggggc agctggagca ctggagcttt tggggcagcc tctggcaaca ggggtgctgg
1921 agttgccagg gcagcctggg gcgccagagt tgcctgggca gcctgtggca actgtggcgc
1981 tggagatctc tgttcagtct gtggtgacaa catcggagct gtcaacgatg accgtgtcgc
2041 agtccctgga ggtgccctcg acgacagcgc tggaatccta taatacggta gcacaggagc
2101 tgcctactac attagtgggg gagacttctg taacagtagg agtggatccc ttgatggccc
2161 cagaatccca tatattagct tctaacacca tggagaccca tatattagca tccaacacca
2221 tggactccca aatgctagcg tccaacacca tggactccca gatgctagca tccaacacca
2281 tggactccca gatgttagcg tctagcacca tggactccca gatgttagca actagctcca
2341 tggactccca gatgttagca actagctcca tggactccca gatgttagca actagcacta
2401 tggactccca gatgttagca accagttcca tggactccca gatgttagca accagctcca
2461 tggactccca gatgttagca accagctcca tggactccca gatgttagca accagctcca
2521 tggactccca gatgttagca accagcacca tggattctca gatgttagca accagcacca
2581 tggactccca gatgttagca actagctcaa tggattccca gatgttagca tctggcacta
2641 tggactctca aatgttagct tctggcacca tggatgctca gatgttagcg tctggtacca
2701 tggatgccca gatgttagcg tctagtaccc aagattctgc tatgttgggt tcaaaatctc
2761 ctgatcccta taggttagct caggatcctt acaggttagc tcaggatccc tataggttgg
2821 gccatgaccc ctatagatta ggtcatgatg cttacaggtt aggacaagac ccttatagat
2881 taggccatga tccctacaga ctaactcctg atccctatag gatgtcacct agaccctaca
2941 ggatagcacc caggtcctat agaatagcac ccaggccata taggttagca cctagacccc
3001 tgatgttagc atctagacgt tctatgatga tgtcctatgc tgcagaacgt tccatgatgt
3061 catcttacga acgctctatg atgtcttatg agcggtctat gatgtcccct atggctgaac
3121 gctctatgat gtcagcctac gagcgctcta tgatgtcagc ctacgagcgc tctatgatgt
3181 cccctatggc tgagcgctct atgatgtcag cttatgaacg ctccatgatg tcagcttatg
3241 aacgctccat gatgtcccca atggctgatc gatctatgat gtccatgggt gctgaccggt
3301 ctatgatgtc gtcatactct gctgctgacc ggtctatgat gtcatcgtac tctgcagctg
3361 accgatctat gatgtcatct tatactgctg atcgttcaat gatgtctatg gctgctgatt
3421 cttacaccga ttcttacact gacacatata cagaggcata tatggtgcca cctttgcctc
3481 ctgaagagcc cccaacaatg ccaccgttgc cacctgagga gccaccaatg acaccaccat
3541 tgcctcctga ggaaccacca gagggtccag cattgcccac tgagcagtca gcattaacag
3601 ctgaaaatac ttggcctaca gaggtgccat cattaccatc tgaagagtct gtatcgcagc
3661 ctgagcctcc tgtgagtcaa agtgagattt cggagccttc agcagtgcct actgattatt
3721 cagtgtcagc atcagatccc tcagttttag tatcagaggc tgctgtgact gttccagaac
3781 caccaccaga gccagaatct tcaattacgt taacacctgt agagtctgca gtagtagcag
3841 aagaacatga agttgttcca gagagaccag tgacttgtat ggtatctgaa actcccgcca
3901 tgtcagctga accaactgtg ttagcatcag agcctcctgt tatgtcagag acagcagaaa
3961 catttgattc catgagagcc tcaggacatg ttgcctcaga agtatctaca tccttgttgg
4021 ttccagcagt aactactcca gtgctggcag agagcattct ggagccgcca gccatggctg
4081 ccccagagtc ttcagctatg gctgtcctgg agtcttcggc tgtgaccgtc ctggagtctt
4141 cgactgtgac tgtcctggag tcttcgactg taactgtcct ggagccttcg gttgtgactg
4201 tcccggagcc tcctgttgtg gctgagccag actatgttac cattcctgtg ccagttgttt
4261 ctgcgctgga gccttctgtg cctgttctgg aaccagcggt gtcagtcctt caaccttcta
4321 tgattgtttc agaaccatct gtttctgtcc aggaatcgac tgtgacagtt tcagagcctg
4381 ctgtcacagt ctcagagcag actcaagtaa taccaactga ggtggctata gagtccacac
4441 caatgatact ggaatctagt atcatgtcat cacatgttat gaaaggaatt aatctatcct
4501 ctggtgatca aaatcttgct ccagagattg gcatgcagga gattgcattg cattcaggtg
4561 aagaaccaca tgctgaggaa cacctgaaag gtgactttta cgaaagtgaa catggtataa
4621 atatagacct taatataaat aatcatttaa ttgctaaaga gatggaacat aatacagtgt
4681 gtgctgctgg tactagtcct gttggggaaa ttggtgaaga gaaaattttg cccaccagtg
4741 agactaaaca gcgcacagta ttggatacct accctggtgt tagtgaagct gatgcaggag
4801 aaactctatc ttctactggt ccttttgctc tggaacctga tgcaacagga actagtaagg
4861 gtattgaatt taccacagca tctactctca gtttagttaa taaatatgat gttgatttat
4921 ctttaactac tcaagatact gaacatgaca tggtaatttc caccagtcct agtggtggta
4981 gtgaagctga cattgaaggg cctttgcctg ctaaagatat tcatcttgat ttaccatcta
5041 ataataacct tgttagtaag gatacagaag aaccattacc tgtaaaagag agtgaccaga
5101 cattagcagc tctgctcagc cctaaagaaa gtagtggagg agaaaaagaa gtacctcccc
5161 ctcctaaaga gacactgcct gattcaggat tttctgccaa tattgaggat attaatgaag
5221 cagatttagt gagaccgtta cttcctaagg acatggaacg tcttacaagc cttagagctg
5281 gcattgaagg acctttactt gcaagtgatg ttggacgtga cagatctgct gccagcccgg
5341 ttgtaagtag tatgccagaa agagcttcag agtcttcttc agaggaaaaa gatgattatg
5401 aaatttttgt aaaagttaag gacactcacg aaaaaagcaa gaaaaataag aaccgtgata
5461 agggggagaa agagaagaaa agagactctt cattaagatc tcgaagtaag cgttccaaat
5521 cttctgaaca caaatcacgc aagcgtacca gtgaatctcg ttctagggca agaaagagat
5581 catctaagtc caagtctcat cgctctcaga cacgttcacg gtcacgttca agacgcagga
5641 ggagaagcag cagatcaaga tcaaagtcta gaggaagaag atctgtatca aaagagaagc
5701 gcaaaagatc tccaaagcac agatccaagt ctagggaaag aaaaagaaaa agatcaagct
5761 ccagggataa ccgaaagaca gttagagctc gaagtcgaac cccaagtcgt cggagtcgga
5821 gtcatactcc aagtcgtcga cgaaggtcta gatctgtggg tagaagaagg agctttagca
5881 tttccccaag ccgccgcagc cgcaccccca gccgccgcag ccgcaccccc agccgccgca
5941 gccgcacccc cagccgccgc agccgcaccc ccagccgccg gagccgcacc cctagccgtc
6001 ggagccgcac cccaagccgc cggagaagat caaggtctgt ggtaagaaga cgaagcttca
6061 gtatctcacc agtcagatta aggcgatcaa gaacaccctt aagaagaagg tttagcagat
6121 ctcccatccg tcgtaaaaga tccaggtctt ctgaacgagg cagatcaccc aaacgtctga
6181 cagatttgga taaggctcaa ttacttgaaa tagccaaagc taatgcagct gccatgtgtg
6241 ctaaggctgg tgtcccttta ccaccaaacc taaagcctgc acctccacct actatagaag
6301 agaaagttgc taaaaagtca ggaggagcta ctatagaaga actaactgag aaatgtaaac
6361 agatcgcaca gagtaaagaa gatgatgatg taatagtgaa taaacctcat gtttcggatg
6421 aagaggaaga agaacctcct ttttatcatc atccctttaa actcagtgaa cccaaaccta
6481 tttttttcaa tctgaatatt gctgcagcaa aaccaactcc accaaaaagc caggtaacat
6541 taacaaaaga attccctgta tcatctggat ctcaacatcg gaaaaaagaa gcggatagtg
6601 tttatggaga atgggttcct gtggagaaaa atggtgaaga aaacaaagat gatgataatg
6661 ttttcagcag caatttgccc tcagagcctg tggacatctc tacagcaatg agtgaacggg
6721 cacttgctca gaaaagactc agtgagaatg catttgatct tgaagccatg agcatgttaa
6781 atagagctca ggaaaggatt gatgcctggg ctcagctgaa ctctattcct ggccagttca
6841 caggaagtac aggagtacag gttttgacac aagaacagtt ggccaatact ggtgcccaag
6901 cctggattaa aaagggccaa atccttgtag ctgtcttctt gccccggtca gtgccagccg
6961 tactattcac aacactgctg ctaccgaggc ctaggatcag ttcttaagag cagccccggt
7021 aactggagga atgggagccg ttttgatgag aaaaatgggc tggagagaag gagaaggatt
7081 aggaaaaaac aaagaaggca ataaggaacc catcctagtt gattttaaga cagaccgaaa
7141 aggtcttgtt gcagtaggag aaagagcaca aaagaggtct gggaacttct ctgctgcaat
7201 gaaagatctg tcaggcaaac atcctgtgtc tgctttgatg gagatctgta ataaaagaag
7261 gtggcaacca cctgaatttc tattggtcca tgatagtggc cctgatcatc gcaaacattt
7321 tctctttagg gtattgataa atggaagcgc ttaccagccc agctttgcca gccctaataa
7381 gaagcatgct aaagccacag cagctactgt ggttcttcaa gcaatgggcc ttgtaccaaa
7441 ggacctcatg gctaatgcca cttgcttcag gagtgcctca cgtagataga ttgaggtttt
7501 ataataatca tttcagaatt ttactctgca tcacaatgta tttcctcttt aatgttgtaa
7561 atatttggca atttaagaca ttgtgtaaaa agcaatctgt aaaaacatct ccaggctttg
7621 atttttgtac catggaaatt gtatttaacc atacagggtt ttggtatgtt tatattgttt
7681 accttagtga tgtatttgtt taagtggcta acatccaaac gactgtttga aggcatcaga
7741 gtaatcttca gtgtggaatg ttaaataacg cttttatact gtattttgta ctatgatgta
7801 actccccttc cttatggcta ggctactgta acacttgcct gtaatcagtg aagggctgtg
7861 caccttgtac tatttcacaa tgggttctgc tggacagata atgggccagt gttattgagg
7921 tgatcaagat ctgttccaca gggctaatgc caccatctcc cctcaaaatt ttgtagaggt
7981 tctaaaaaga aagtggtatg ttgtgtgatg atcagcacta agtcctgcat tcctgttaaa
8041 gccacttggg tcataagaag ggagtaaaaa atgaagtctg actagaattc tattgcagag
8101 gccaagtaca tttagtatgg cattgagttg tgatatagtt ttactttgat gtgcattttg
8161 aatttcagct acacctagat agacgtaaaa tgataattaa aatgctgtaa ccaacttatc
8221 taataaaatt ggcaaccagc cactattttg ttgactatga gaaagttaaa agtttatgtt
8281 aatttttagg gtctgataga atatttcatg tgtattacag tggtattcat atgctatgtc
8341 tctaaacttt attttcaaaa gcttaaggcc caaatacaaa cttctctgga ataaa
//