LOCUS AF378756 6702 bp mRNA linear HUM 07-OCT-2001
DEFINITION Homo sapiens tumor endothelial marker 6 (TEM6) mRNA, complete cds.
ACCESSION AF378756
VERSION AF378756.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6702)
AUTHORS Carson-Walter,E.B., Watkins,D.N., Nanda,A., Vogelstein,B.,
Kinzler,K.W. and St Croix,B.
TITLE Cell surface tumor endothelial markers are conserved in mice and
humans
JOURNAL Cancer Res. 61 (18), 6649-6655 (2001)
PUBMED 11559528
REFERENCE 2 (bases 1 to 6702)
AUTHORS Carson-Walter,E.B., Vogelstein,B., Kinzler,K.W. and St. Croix,B.
TITLE Direct Submission
JOURNAL Submitted (10-MAY-2001) Oncology, Johns Hopkins University, 1650
Orleans Street, Baltimore, MD 21231, USA
FEATURES Location/Qualifiers
source 1..6702
/db_xref="H-InvDB:HIT000078600"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..6702
/gene="TEM6"
CDS 93..3710
/gene="TEM6"
/codon_start=1
/product="tumor endothelial marker 6"
/protein_id="AAL11993.1"
/translation="MVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASK
DDRFPDYGKVELVFSATPEKIQGSEHLYNDHGVIVDYNTTDPLIRWDSYENLSADGEV
LHTQGPVDGSLYAKVRKKSSSDPGIPGGPQAIPATNSPDHSDHTLSVSSDSGHSTASA
RTDKTEERLAPGTRRGLSAQEKAELDQLLSGFGLEDPGSSLKEMTDARSKYSGTRHVV
PAQVHVNGDAALKDRETDILDDEMPHHDLHSVDSLGTLSSSEGPQSAHLGPFTCHKSS
QNSLLSDGFGSNVGEDPQGTLVPDLGLGMDGPYERERTFGSREPKQPQPLLRKPSVSA
QMQAYGQSSYSTQTWVRQQQMVVAHQYSFAPDGEARLVSRCPADNPGLVQAQPRVPLT
PTRGTSSRVAVQRGVGSGPHPPDTQQPSPSKAFKPRFPGDQVVNGAGPELSTGPSPGS
PTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGSQANGSVSPDSVGGGLRASSRLPD
TGEGPSRATGRQGSSAEQPLGGRLRKLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNL
PPFPSPADVKETMTPGYPQDLDIIDGRILSSKESMCSTPAFPVSPETPYVKTALRHPP
FSPPEPPLSSPASQHKGGREPRSCPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQ
AFASSCTISSNGPGQRRESSSSAERQWVESSPKPMVSLLGSGRPTGSPLSAEFSGTRK
DSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPPSSQAFLGFGTAPVGSGLPPEEDLG
ALLANSHGASPTPSIPLTATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQGVTLPGQP
PLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAASPLPDS
PGDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKEPGSFIVRDSHSFRGAYGLAMKV
ATPPPSVLQLNKKAGDLANELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSIT
PLALPCKLLIPERDPLEEIAESSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQ
AIQKALSITLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVNSVIFCALDPQ
DRKWIKDGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPKK
V"
BASE COUNT 1564 a 1880 c 1817 g 1441 t
ORIGIN
1 ccccgactag cccgacagtc cccgactagc ccgacagccc cagcaggatc tgcatcgtca
61 tcgagccggc ccagcttctg aagggagatg tcatggtgaa atgctaccac aagaaatacc
121 gctcggccac ccgtgacgtc attttccgcc tgcagtttca cactggggct gtgcagggct
181 acgggctggt gtttgggaag gaggatctgg acaatgccag caaagatgac cgttttcctg
241 actatgggaa ggttgaatta gtcttctctg ccacgcctga gaagattcaa gggtccgaac
301 acttgtacaa cgaccacggt gtgattgtgg actacaacac aacagaccca ctgatacgct
361 gggactcgta cgagaacctc agtgcagatg gagaagtgct acacacgcag ggccctgtcg
421 atggcagcct ttacgcgaag gtgaggaaga aaagctcctc ggatcctggc atcccaggtg
481 gcccccaggc aatcccggcc accaacagcc cagaccacag tgaccacacc ttgtctgtca
541 gcagtgactc cggccactct acagcctctg ccaggacgga taagacggaa gagcgcctgg
601 ccccaggaac caggaggggc ctgagtgccc aggagaaggc agagttggac cagctgctca
661 gtggctttgg cctggaagat cctggaagct ccctcaagga aatgactgat gctcgaagca
721 agtacagtgg gacccgccac gtggtgccag cccaggttca cgtgaatgga gacgctgctc
781 tgaaggatcg ggagacagac attctggatg acgagatgcc ccaccacgac ctgcacagtg
841 tggacagcct tgggaccctg tcctcctcgg aagggcctca gtcggcccac ctgggtccct
901 tcacctgcca caagagcagc cagaactcac tcctatctga cggttttggc agcaacgttg
961 gtgaagatcc gcagggcacc ctcgttccgg acctgggcct tggcatggac ggcccctatg
1021 agcgggagcg gacttttggg agtcgagagc ccaagcagcc ccagcccctg ctgagaaagc
1081 cctcagtgtc cgcccagatg caggcctatg ggcagagcag ctactccaca cagacctggg
1141 tgcgccagca gcagatggtt gtagctcacc agtatagctt cgccccagat ggggaggccc
1201 ggctggtgag ccgctgccct gcagacaatc ctggcctcgt ccaggcccag cccagagtgc
1261 cactcacccc cacccgaggg accagcagta gggtggctgt ccagaggggt gtaggcagtg
1321 ggccacatcc ccctgacaca cagcagccct ctcccagcaa agcgttcaaa cccaggtttc
1381 caggagacca ggttgtgaat ggagccggcc cagagctgag cacaggcccc tccccaggct
1441 cgcccaccct ggacatcgac cagtccatcg agcagctcaa caggctgatc ctggagctgg
1501 atcccacctt cgagcccatc cctacccaca tgaacgccct cggtagccag gccaatggct
1561 ctgtgtctcc agacagcgtg ggaggtgggc tccgggcaag cagcaggctg cctgacacag
1621 gagagggccc cagcagggcc accgggcggc aaggctcctc tgctgaacag cccctgggcg
1681 ggagactcag gaagctgagc ctggggcagt acgacaacga tgctgggggg cagctgccct
1741 tctccaaatg tgcatgggga aaggctggtg tggactatgc cccaaacctg ccgccattcc
1801 cctcaccagc ggacgtcaaa gagacgatga cccctggcta tccccaggac ctcgatatta
1861 tcgatggcag aattttaagt agcaaggagt ccatgtgttc aactccagca tttcctgtgt
1921 ctccagagac accgtatgtg aaaacagcgc tgcgccatcc tccgttcagc ccacctgagc
1981 ccccgctgag cagcccagcc agtcagcaca aaggaggacg tgaaccacga agctgccctg
2041 agacgctcac tcacgctgtg gggatgtcag agagccccat cggacccaaa tccacgatgc
2101 tccgggctga tgcgtcctcg acgccctcct ttcagcaggc ttttgcttct tcctgcacca
2161 tttccagcaa cggccctggg cagaggagag agagctcctc ttctgcagaa cgccagtggg
2221 tggagagcag ccccaagccc atggtttccc tgctggggag cggccggccc accggaagtc
2281 ccctcagcgc tgagttctcc ggtaccagga aggactcccc agtgctgtcc tgcttcccgc
2341 cgtcagagct ccaggctcct ttccacagcc atgagctgtc cctagcagag ccaccggact
2401 ccctggcgcc tcccagcagc caggccttcc tgggcttcgg caccgcccca gtgggaagtg
2461 gccttccgcc cgaggaggac ctgggggcct tgctggccaa ttctcatgga gcgtcaccga
2521 cccccagcat cccgctgaca gcgacagggg ctgccgacaa tggcttcctg tcccacaact
2581 ttctcacggt ggcgcctgga cacagcagcc accacagtcc aggcctgcag ggccagggtg
2641 tgaccctgcc cgggcagcca cccctccctg agaagaagcg ggcctcggag ggggatcgtt
2701 ctttgggctc agtctctccc tcctccagtg gcttctccag cccgcacagc gggagcacca
2761 tcagtatccc cttcccaaat gtccttcccg acttttccaa ggcttcagaa gcggcctcac
2821 ctctgccaga tagtccaggt gataaacttg tgatcgtgaa atttgttcaa gacacttcca
2881 agttctggta caaggcggat atttcaagag aacaagccat cgccatgttg aaggacaagg
2941 agccgggctc attcattgtt cgagacagcc attccttccg aggggcctat ggcctggcca
3001 tgaaggtggc cacgccccca ccttcagtcc tgcagctgaa caagaaagct ggagatttgg
3061 ccaatgaact cgtccggcac tttttgatcg agtgtacccc gaagggagtg cggttgaaag
3121 ggtgctcgaa tgaaccatat ttcgggagcc tgacggcctt ggtgtgccag cattccatca
3181 cgcccttggc cttgccgtgc aagctgctta tcccagagag agatccattg gaggaaatag
3241 cagaaagttc tccccagacg gcagccaatt cagcagctga gctgttgaag cagggggcag
3301 cctgcaacgt gtggtacttg aactctgtgg agatggagtc cctcaccggc caccaggcga
3361 tccagaaggc cctgagcatc accctggtcc aggagcctcc acctgtgtcc acagttgtgc
3421 acttcaaggt gtcagcccag ggcatcaccc tgacagacaa tcagaggaag ctcttcttcc
3481 ggaggcatta ccccgtgaac agtgtgattt tctgtgcctt ggacccacaa gacaggaagt
3541 ggatcaaaga tggcccttcc tcaaaagtct ttggatttgt ggcccggaag cagggcagtg
3601 ccacggataa tgtgtgccac ctgtttgcag agcatgaccc tgagcagcct gccagtgcca
3661 ttgtcaactt cgtatcaaag gtcatgattg gttccccaaa gaaggtctga gaactcccct
3721 ccctccctgg acccaccgat gcctctcgaa gccctggaga cagccgttgg gtgagggtgg
3781 ggcccccact ttttaccaaa ctagtaaacc tgacattcca ggcccatgag gggaaagagg
3841 atcttccagc tctgcaaaaa caagaacaaa caacatcacc gtgaattggc ctttcctgaa
3901 agtgacttat ctgacacatc tctgtagcca catgcttttt gggtagaaga agctgggcat
3961 gggtgcaccc caccccctag ggtccccatg ggaaagggac atgcaaggaa acagcacaga
4021 acacgaggtg gtccccatgt ccctggcaca ctagcattcc gggggatgag gaatccccag
4081 cccttgaggc agaggtgccg agtgactgcc atgcttcgcc cgtccgcatg ggcgcttctg
4141 tccagctgca cccgaggccg ggggtttccc tcacctcggt cttcccaaga tggagatgct
4201 aacgaaactg agaagggggc gtatgtttga cgaaggtttg tgcaagtcag gcccttctgg
4261 aacacagcag ggcctacaac gaggggcctt tgcgatgggc tgtgaggatg ggggtggtgg
4321 gaagaattgg ccacgttaga gaccccatgc caccccacca tggtgagtgc tctgtgcctc
4381 ctgctcacct gtggtgagct gggcgagctg ggcgagctgg gcgagctggg ctggggagag
4441 cctgtgagga ccgagaggag aaatgagaag aaggaacaaa aatattattt ctatgtaatt
4501 tatattttac ttatgccaaa ttatttatga taatttgcca ttgctatact gtaccagtgt
4561 caaatgctgc agcctgccaa gctgtgattt tgtgaggctt gtccctatgt aggatgcacc
4621 gcaggcccct ggccactgaa agagtgtgca gtggactgtg ggtctcccat atgcggtgcc
4681 gcccaaaggt ggctttgcct caagcaacct accctgatgt tttactcatt ggaatgtttt
4741 tccccgattg tggatgactt cttttctgat ggagagagtc caggagggat ggaaaactcc
4801 tggatttaag ctcagcatcc cccacatggg cttttcgatc atcttcaggc ctgaagctgc
4861 acgacctgaa gttcgcctgc atttatcagc cctctttgtg ctgctccttg ccaccttggg
4921 gttcctgctg gggaccatgt gtggttgtgg catgtgtgag cagaagggag gatgaggaaa
4981 aagagaagaa accccggtac tgacaagctg tttttgagtg ccactgtttg ccatcatcta
5041 agccactgaa tcaagtgtat ttcaggctta tttcaacatt ccaatgccct ggttttcctg
5101 cttgaatctg ttcgtggtca aaggtttggg ggaatttgtg accctggaac atccccagag
5161 tgaaagatgg agctgggcca catcagaata aggccttggc cccatcctct cacagcctag
5221 gtgctctgca ggcatgctga ctgtcctgat tgcgatccag cccgaaattc cctcctctgc
5281 tttcaaaagt caaatccccc attcttaggc cacactggtg tcacaagctc ctgtcaggga
5341 gctggggttt gggaatgtgc tttgtgaact ctgctttaaa gtgaggggcc gaggaaaact
5401 tagaaacagg cagagttgga agcagccaaa tcacagtggg tgttgtgtgt gtgtgcgtgt
5461 gtgcatgcgt gcgtgtatgc gtgtgtgaaa gcaggtggac cattccactt tttagctcct
5521 attgatgcac caaaccaagt gcctcatttc tgtgccaaat gtttgccttg gtcgttgtgg
5581 acctccttct ctaacttgcg gtggcatgac tgtcaggagg tgctggcatt ttcagcagat
5641 cctcatgtgt tgaccctgat gtctttagca gaggcctcta gcatctcggt ttttcatcca
5701 ctgcaggaat gtggccacag ggagcagagg tttgtacttt ccccaagagg tcctcatcct
5761 gagacggtct ctacccatgt ttaacccaaa gagtgcaggc caggttcctt atccttctga
5821 tgaaggatga gagagctcat ttagaagtca gagcaaacta gggtctcagt attgagaaac
5881 gcagcctgcc agggaatcac agagacatcg gggtgcccgc gatggccctc atgaagccat
5941 gcctcgacgg cattcaggaa gccctgcaaa cgtgcttttt gaactcattg gccaggtgtg
6001 atttttacac aaggtaaacg tggtcaaggg catcggggaa tttgctccaa gcagatagct
6061 ccctctgagg aaccaaagga agcaagtttc cacgatttct gaagagctgg tataggaagt
6121 ttctttcttc cttttgtgtt acatgtgcat taaacagaac aagctgtgtg tcatcacaga
6181 ttgtactgtg ggctcagaaa ccgtgagaga gcccccaccg tggacaccgg ctctagggcc
6241 acaggaaaag gaacgtttcc aggcattttg tctccagggc tcccgctgga caggcacgta
6301 ctgccctggg gagtaaatgc ggagagttca cgaactgtgc ccaacgcatg ttatagccag
6361 ggtcctacta actactcagt aaaagaacgt attgttgtat tcctccagtg ttaagctata
6421 gccatgttaa aagtcactgt gcatttattc tcagcatcaa ataccttgta acgtcttctc
6481 tgccttgtta gtgcatattt ttacttttct gatactgtaa agaatatatc cagtatgtaa
6541 atgaatgttc tataaatctt ttgtatagtc attttctctg ctccttaaat atcatctcta
6601 ttcagagtat aataaaatta tgaacttggt aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
6661 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//