LOCUS AF376803 5454 bp mRNA linear HUM 14-MAY-2003
DEFINITION Homo sapiens neuroligin X mRNA, complete cds.
ACCESSION AF376803
VERSION AF376803.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5454)
AUTHORS Jamain,S., Quach,H., Betancur,C., Rastam,M., Colineaux,C.,
Gillberg,I.C., Soderstrom,H., Giros,B., Leboyer,M., Gillberg,C.,
Bourgeron,T., Gillberg,C., Rastam,M., Gillberg,C., Nyden,A.,
Soderstrom,H., Leboyer,M., Betancur,C., Philippe,A., Giros,B.,
Colineaux,C., Cohen,D., Chabane,N., Mouren-Simeoni,M.C., Brice,A.,
Sponheim,E., Spurkland,I., Skjeldal,O.H., Coleman,M., Pearl,P.L.,
Cohen,I.L., Tsiouris,J., Zappella,M., Menchetti,G., Pompella,A.,
Aschauer,H. and Van Maldergem,L.
TITLE Mutations of the X-linked genes encoding neuroligins NLGN3 and
NLGN4 are associated with autism
JOURNAL Nat. Genet. 34 (1), 27-29 (2003)
PUBMED 12669065
REFERENCE 2 (bases 1 to 5454)
AUTHORS Jamain,S., Quach,H., Fellous,M. and Bourgeron,T.
TITLE Evolution and expression of the human neuroligin family, including
two primate specific members on the X and Y chromosomes
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 5454)
AUTHORS Jamain,S., Quach,H., Fellous,M. and Bourgeron,T.
TITLE Direct Submission
JOURNAL Submitted (04-MAY-2001) Immunology, Institut Pasteur, 25 rue du
Docteur Roux, Paris 75015, France
FEATURES Location/Qualifiers
source 1..5454
/db_xref="H-InvDB:HIT000078585"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X"
/map="Xp22.31"
CDS 465..2915
/note="HLNX"
/codon_start=1
/product="neuroligin X"
/protein_id="AAM46112.1"
/translation="MSRPQGLLWLPLLFTPVCVMLNSNVLLWLTALAIKFTLIDSQAQ
YPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRN
TTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIH
DQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAA
KGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKA
IIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPA
TYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTP
NDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWV
APAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELF
SCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKD
QLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLNEIFQYVSTTTKVPPPDMTSFPYG
TRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPEDTTVLIETKRDYSTELSVTIAVG
ASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNTTNDIAHIQNEEIMSLQMKQLEHD
HECESLQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNTITMIPNTLTGMQPLHTFNTF
SGGQNSTNLPHGHSTTRV"
BASE COUNT 1514 a 1314 c 1208 g 1418 t
ORIGIN
1 atttaagcga ttttttttcc ctccttcatc gccgggcctc ggataagatg acggcttggg
61 tgatgcacga aataacgcac gtgattgatt agacctggct tggcttggct agggaacgat
121 ccaggcgcgc tggagacccc gcgtgaagat gaaatgacgg ctgccttgga gttttcataa
181 gaaattgtcc ctggaggtgt tggatgatca cagcttcctt ggagcattgc agttgctgga
241 atccagtttc aggattaagg gagggctgcc tccttgcaat gggctgccaa gaaaacggct
301 gtgcttgttc ttaacctcag gctctgtctg tgatcagtct gagagtctct cccaggtcta
361 ctgctccctg gaaagcccta tctctctgca ggctcgcctc tgggctttgt ctccttggag
421 ccacatcact gggacagctg tggatgtgga tgcagatttg aaccatgtca cggccccagg
481 gactgctatg gcttcctttg ttgttcaccc cggtctgcgt catgttaaac tccaatgtcc
541 tcctgtggtt aactgctctt gccatcaagt tcaccctcat tgacagccaa gcacagtatc
601 cagttgtcaa cacaaattat ggcaaaatcc ggggcctaag aacaccgtta cccaatgaga
661 tcttgggtcc agtggagcag tacttagggg tcccctatgc ctcacccccc actggagaga
721 ggcggtttca gcccccagaa cccccgtcct cctggactgg catccgaaat actactcagt
781 ttgctgctgt gtgcccccag cacctggatg agagatcctt actgcatgac atgctgccca
841 tctggtttac cgccaatttg gatactttga tgacctatgt tcaagatcaa aatgaagact
901 gcctttactt aaacatctac gtgcccacgg aagatgatat tcatgatcag aacagtaaga
961 agcccgtcat ggtctatatc catgggggat cttacatgga gggcaccggc aacatgattg
1021 acggcagcat tttggcaagc tacggaaacg tcatcgtgat caccattaac taccgtctgg
1081 gaatactagg gtttttaagt accggtgacc aggcagcaaa aggcaactat gggctcctgg
1141 atcagattca agcactgcgg tggattgagg agaatgtggg agcctttggc ggggacccca
1201 agagagtgac catctttggc tcgggggctg gggcctcctg tgtcagcctg ttgaccctgt
1261 cccactactc agaaggtctc ttccagaagg ccatcattca gagcggcacc gccctgtcca
1321 gctgggcagt gaactaccag ccggccaagt acactcggat attggcagac aaggtcggct
1381 gcaacatgct ggacaccacg gacatggtag aatgcctgcg gaacaagaac tacaaggagc
1441 tcatccagca gaccatcacc ccggccacct accacatagc cttcgggccg gtgatcgacg
1501 gcgacgtcat cccagacgac ccccagatcc tgatggagca aggcgagttc ctcaactacg
1561 acatcatgct gggcgtcaac caaggggaag gcctgaagtt cgtggacggc atcgtggata
1621 acgaggacgg tgtgacgccc aacgactttg acttctccgt gtccaacttc gtggacaacc
1681 tttacggcta ccctgaaggg aaagacactt tgcgggagac tatcaagttc atgtacacag
1741 actgggccga taaggaaaac ccggagacgc ggcggaaaac cctggtggct ctctttactg
1801 accaccagtg ggtggccccc gccgtggcca ccgccgacct gcacgcgcag tacggctccc
1861 ccacctactt ctatgccttc tatcatcact gccaaagcga aatgaagccc agctgggcag
1921 attcggccca tggtgatgag gtcccctatg tcttcggcat ccccatgatc ggtcccaccg
1981 agctcttcag ttgtaacttt tccaagaacg acgtcatgct cagcgccgtg gtcatgacct
2041 actggacgaa cttcgccaaa actggtgatc caaatcaacc agttcctcag gataccaagt
2101 tcattcacac aaaacccaac cgctttgaag aagtggcctg gtccaagtat aatcccaaag
2161 accagctcta tctgcatatt ggcttgaaac ccagagtgag agatcactac cgggcaacga
2221 aagtggcttt ctggttggaa ctcgttcctc atttgcacaa cttgaacgag atattccagt
2281 atgtttcaac aaccacaaag gttcctccac cagacatgac atcatttccc tatggcaccc
2341 ggcgatctcc cgccaagata tggccaacca ccaaacgccc agcaatcact cctgccaaca
2401 atcccaaaca ctctaaggac cctcacaaaa cagggcctga ggacacaact gtcctcattg
2461 aaaccaaacg agattattcc accgaattaa gtgtcaccat tgccgtcggg gcgtcgctcc
2521 tcttcctcaa catcttagct tttgcggcgc tgtactacaa aaaggacaag aggcgccatg
2581 agactcacag gcgccccagt ccccagagaa acaccacaaa tgatatcgct cacatccaga
2641 acgaagagat catgtctctg cagatgaagc agctggaaca cgatcacgag tgtgagtcgc
2701 tgcaggcaca cgacacactg aggctcacct gcccgccaga ctacaccctc acgctgcgcc
2761 ggtcgccaga tgacatccca cttatgacgc caaacaccat caccatgatt ccaaacacac
2821 tgacggggat gcagcctttg cacactttta acaccttcag tggaggacaa aacagtacaa
2881 atttacccca cggacattcc accactagag tatagctttg ccctatttcc cttcctatcc
2941 ctctgcccta cccgctcagc aacatagaag agggaaggaa agagagaagg aaagagagag
3001 agaaagaaag tctccagacc aggaatgttt ttgtcccact gacttaagac aaaaatgcaa
3061 aaaggcagtc atcccatccc ggcagaccct tatcgttggt gttttccagt attacaagat
3121 caacttctga ccctgtgaaa tgtgagaagt acacatttct gttaaaataa ctgctttaag
3181 atctctacca ctccaatcaa tgtttagtgt gataggacat caccatttca aggccccggg
3241 tgtttccaac gtcatggaag cagctgacac ttctgaaact cagccaagga cacttgatat
3301 tttttaatta caatggaagt ttaaacattt ctttctgtgc cacacaatgg atggctctcc
3361 ttaagtgaag aaagagtcaa tgagattttg cccagcacat ggagctgtaa tccagagaga
3421 aggaaacgta gaaatttatt attaaaagaa tggactgtgc agcgaaatct gtacggttct
3481 gtgcaaagag gtgttttgcc agcctgaact atatttaaga gactttgtaa aaaagaaaaa
3541 tgtatatagc tgtgagttta aacaaaaacc acaaacagac aaacaagaaa aaaagctttt
3601 attggtgttt tcactttgaa agagctttta gcaaggttgt gcttttcatt gtgctctgta
3661 cgtatataaa tatatatata tacacacaca cacacacaca ttagtcatat cacctctgtt
3721 tcctccccaa caaaagaggc ttttcttctt aattacttgt ggtaaacaaa gacatgggat
3781 tttcttacat gagattctca tttgtaggag gatgtgatgt cccacagaag acccagacgg
3841 tctgtgtggc ctatttcccc cgtcaggttg cacaggtgca tgcaagagca ttcttaggag
3901 accactgttt tgaaaaactt ttgacttgta cgtgttagcc ttcatgaaat tgcagtacag
3961 agatgggtcc ccaaagtgga gtgtatttac agcttgttaa attagagaca tgcacacaca
4021 aagaatcagt agggagaaac aaaaatacaa gtcccgttct gtagctctgg ccctttgaat
4081 atgtttagga agagttgctt cccatttcag ggccctgcca aaaaaagaag aaagcttgcc
4141 tttggtgggg ctatgcccct tggagtaaat acggctctgt gttccctagc agctgcggga
4201 gggtttggcc gatgaagtac ctgctcagct tagctaatca gattgaagga agacatgtgt
4261 ctttcctttt tgtttaagca ctcggtccct tatttatcag taagcaggtt tttaaaaatc
4321 ttttatatca tttatgggat caaacatatg attgtctgaa aacatcactt tttgtggatt
4381 tgtgtatccg gtcaccaaac ggtgaatatt atagaagaat gggggaagaa aggatagaat
4441 attaaaactg ctttgcatgg gttttctggg aaattaggat aacttcactg agaagacatt
4501 gaatggaaat tattcaccca ttttaaattg gtgacctagg gatcagagat ttgtctttcc
4561 aacagcttgt cattttttca tttctcttct catttttcag gaaagttttg agtgttataa
4621 ggtggaagga aacatagtag caatggatac ttttttgaaa aattattgca ttaccaagaa
4681 acagtagcca aagatatttg aagatcatgt tcctcggctc cattgtgggt tattctagaa
4741 atccagtctt aaatctctcc gctaaagtgg acattcccca taaaaattgt ccagctgcct
4801 ggctcttttg caataacaac ctttgattac tgaatcccta cactcaaact atagtgatat
4861 atcagtgttt gagagtgacc tctagaaaaa agaaaagtgt ttttagaaat gtgtacaagt
4921 cacccccaaa tcctattgct tatcttgggt taaatttgag agtgattctc tgtatataaa
4981 tatgtgaaat attattatct caacttagca cacgtgaagc aacatttctt tcctacagag
5041 aggtgtcatg gtaagatttc attccgaatt cattgtttca tagagctatg atcaggccat
5101 ttctgcaagc aatgtatgac cccacctgag caaccacaaa taggctctct gtgaaactac
5161 aaaggaagtt atgtgtggca tccatgttgg tttcgtctgt ctgtaatgtg aattccagta
5221 tttgtttagt atttccagtt gtctcctgct agcaatatgt acagtaacgc gtcaggcttg
5281 tgacatttga ataaggaaaa acagagttcc tgttaagtga ataactttag cttttacagg
5341 ggattatgat caaaagtgat tttagtacat cttaaatgat atcttatttc tacatggaaa
5401 gaagttatag aatcttcata gagttctatg agaaaaaata tacttgctat ctat
//