LOCUS AF376061 3581 bp mRNA linear HUM 15-MAY-2001
DEFINITION Homo sapiens caspase recruitment domain protein 12 mRNA, complete
cds.
ACCESSION AF376061
VERSION AF376061.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3581)
AUTHORS Gingras,M.-C., Qiu,J. and Margolin,J.F.
TITLE Differential expression of the caspase recruitment domain protein
12 (CARD12) during monocytic differentiation
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 3581)
AUTHORS Gingras,M.-C., Qiu,J. and Margolin,J.F.
TITLE Direct Submission
JOURNAL Submitted (03-MAY-2001) Pediatric/Texas Children's Cancer Center,
Baylor College of Medicine, 6621 Fannin St. MC3-3320, Houston, TX
77030, USA
FEATURES Location/Qualifiers
source 1..3581
/db_xref="H-InvDB:HIT000078582"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2p21-22"
/cell_line="U937"
/cell_type="peripheral blood-derived CD14 mature monocyte"
CDS 490..3564
/note="CARD12"
/codon_start=1
/product="caspase recruitment domain protein 12"
/protein_id="AAK53443.1"
/translation="MNFIKDNSRALIQRMGMTVIKQITDDLFVWNVLNREEVNIICCE
KVEQDAARGIIHMILKKGSESCNLFLKSLKEWNYPLFQDLNGQSLFHQTSEGDLDDLA
QDLKDLYHTPSFLNFYPLGEDIDIIFNLKSTFTEPVLWRKDQHHHRVEQLTLNGLLQA
LQSPCIIEGESGKGKSTLLQRIAMLWGSGKCKALTKFKFVFFLRLSRAQGGLFETLCD
QLLDIPGTIRKQTFMAMLLKLRQRVLFLLDGYNEFKPQNCPEIEALIKENHRFKNMVI
VTTTTECLRHIRQFGALTAEVGDMTEDSAQALIREVLIKELAEGLLLQIQKSRCLRNL
MKTPLFVVITCAIQMGESEFHSHTQTTLFHTFYDLLIQKNKHKHKGVAASDFIRSLDH
CGDLALEGVFSHKFDFELQDVSSVNEDALLTTGLLCKYTAQRFKPKYKFFHKSFQEYT
AGRRLSSLLTSHEPEEVTKGNGYLQKMVSISDITSTYSSLLRYTCGSSVEATRAVMKH
LAAVYQHGCLLGLSIAKRPLWRQESLQSVKNTTEQEILKAININSFVECGIHLYQEST
SKSALSQEFEAFFQGKSLYINSGNIPDYLFDFFEHLPNCASALDFIKLDFYGGAMASW
EKAAEDTGGIHMEEAPETYIPSRAVSLFFNWKQEFRTLEVTLRDFSKLNKQDIRYLGK
IFSSATSLRLQIKRCAGVAGSLSLVLSTCKNIYSLMVEASPLTIEDERHITSVTNLKT
LSIHDLQNQRLPGGLTDSLGNLKNLTKLIMDNIKMNEEDAIKLAEGLKNLKKMCLFHL
THLSDIGEGMDYIVKSLSSEPCDLEEIQLVSCCLSANAVKILAQNLHNLVKLSILDLS
ENYLEKDGNEALHELIDRMNVLEQLTALMLPWGCDVQGSLSSLLKHLEEVPQLVKLGL
KNWRLTDTEIRILGAFFGKNPLKNFQQLNLAGNRVSSDGWLAFMGVFENLKQLVFFDF
STKEFLPDPALVRKLSQVLSKLTFLQEARLVGWQFDDDDLSVITGAFKLVTA"
misc_feature 502..741
/note="Region: caspase recruitment domain"
BASE COUNT 1033 a 781 c 843 g 924 t
ORIGIN
1 agaatgtcat cctcaaggga agtgcagaga gatttcttca gtcctcagct gagtataagc
61 tggcctcctg gagtctgtga acacaaacgt ccaatgtgag tgtgcctgtg caagcccctg
121 gctgtttata ctccggaggg tgtccccgtg cgtcatcggt ggagtggacc aaaactggtg
181 atctgtttgc cctgtgtgac cttgcccaga accctgctga ctgagagaac acatctgctg
241 gaagtcctct gggattcaag gtacaggaag aactcgaggc ctcactgaaa cggaaagcaa
301 atacaaagaa actttatttt aaaaacgtgt cttggtctcc caagaagagg gcaattggat
361 tgctcagcca gaatgaagag tagttttaca gaaaaaagag gacaatattg ggatcacctt
421 tgacctttcc atttggaaat aatattttct attgtgttat agaaaggtgg gaagctttca
481 tccagaacaa tgaatttcat aaaggacaat agccgagccc ttattcaaag aatgggaatg
541 actgttataa agcaaatcac agatgaccta tttgtatgga atgttctgaa tcgcgaagaa
601 gtaaacatca tttgctgcga gaaggtggag caggatgctg ctagagggat cattcacatg
661 attttgaaaa agggttcaga gtcctgtaac ctctttctta aatcccttaa ggagtggaac
721 tatcctctat ttcaggactt gaatggacaa agtctttttc atcagacatc agaaggagac
781 ttggacgatt tggctcagga tttaaaggac ttgtaccata ccccatcttt tctgaacttt
841 tatccccttg gtgaagatat tgacattatt tttaacttga aaagcacctt cacagaacca
901 gtcctgtgga ggaaggacca acaccatcac cgcgtggagc agctgaccct gaatggcctc
961 ctgcaggctc ttcagagccc ctgcatcatt gaaggggaat ctggcaaagg caagtccact
1021 ctgctgcagc gcattgccat gctctggggc tccggaaagt gcaaggctct gaccaagttc
1081 aaattcgtct tcttcctccg tctcagcagg gcccagggtg gactttttga aaccctctgt
1141 gatcaactcc tggatatacc tggcacaatc aggaagcaga cattcatggc catgctgctg
1201 aagctgcggc agagggttct tttccttctt gatggctaca atgaattcaa gccccagaac
1261 tgcccagaaa tcgaagccct gataaaggaa aaccaccgct tcaagaacat ggtcatcgtc
1321 accactacca ctgagtgcct gaggcacata cggcagtttg gtgccctgac tgctgaggtg
1381 ggggatatga cagaagacag cgcccaggct ctcatccgag aagtgctgat caaggagctt
1441 gctgaaggct tgttgctcca aattcagaaa tccaggtgct tgaggaatct catgaagacc
1501 cctctctttg tggtcatcac ttgtgcaatc cagatgggtg aaagtgagtt ccactctcac
1561 acacaaacaa cgctgttcca taccttctat gatctgttga tacagaaaaa caaacacaaa
1621 cataaaggtg tggctgcaag tgacttcatt cggagcctgg accactgtgg agacctagct
1681 ctggagggtg tgttctccca caagtttgat ttcgaactgc aggatgtgtc cagcgtgaat
1741 gaggatgccc tgctgacaac tgggctcctc tgtaaatata cagctcaaag gttcaagcca
1801 aagtataaat tctttcacaa gtcattccag gagtacacag caggacgaag actcagcagt
1861 ttattgacgt ctcatgagcc agaggaggtg accaagggga atggttactt gcagaaaatg
1921 gtttccattt cggacattac atccacttat agcagcctgc tccggtacac ctgtgggtca
1981 tctgtggaag ccaccagggc tgttatgaag cacctcgcag cagtgtatca acacggctgc
2041 cttctcggac tttccatcgc caagaggcct ctctggagac aggaatcttt gcaaagtgtg
2101 aaaaacacca ctgagcaaga aattctgaaa gccataaaca tcaattcctt tgtagagtgt
2161 ggcatccatt tatatcaaga gagtacatcc aaatcagccc tgagccaaga atttgaagct
2221 ttctttcaag gtaaaagctt atatatcaac tcagggaaca tccccgatta cttatttgac
2281 ttctttgaac atttgcccaa ttgtgcaagt gccctggact tcattaaact ggacttttat
2341 gggggagcta tggcttcatg ggaaaaggct gcagaagaca caggtggaat ccacatggaa
2401 gaggccccag aaacctacat tcccagcagg gctgtatctt tgttcttcaa ctggaagcag
2461 gaattcagga ctctggaggt cacactccgg gatttcagca agttgaataa gcaagatatc
2521 agatatctgg ggaaaatatt cagctctgcc acaagcctca ggctgcaaat aaagagatgt
2581 gctggtgtgg ctggaagcct cagtttggtc ctcagcacct gtaagaacat ttattctctc
2641 atggtggaag ccagtcccct caccatagaa gatgagaggc acatcacatc tgtaacaaac
2701 ctgaaaacct tgagtattca tgacctacag aatcaacggc tgccgggtgg tctgactgac
2761 agcttgggta acttgaagaa ccttacaaag ctcataatgg ataacataaa gatgaatgaa
2821 gaagatgcta taaaactagc tgaaggcctg aaaaacctga agaagatgtg tttatttcat
2881 ttgacccact tgtctgacat tggagaggga atggattaca tagtcaagtc tctgtcaagt
2941 gaaccctgtg accttgaaga aattcaatta gtctcctgct gcttgtctgc aaatgcagtg
3001 aaaatcctag ctcagaatct tcacaatttg gtcaaactga gcattcttga tttatcagaa
3061 aattacctgg aaaaagatgg aaatgaagct cttcatgaac tgatcgacag gatgaacgtg
3121 ctagaacagc tcaccgcact gatgctgccc tggggctgtg acgtgcaagg cagcctgagc
3181 agcctgttga aacatttgga ggaggtccca caactcgtca agcttgggtt gaaaaactgg
3241 agactcacag atacagagat tagaatttta ggtgcatttt ttggaaagaa ccctctgaaa
3301 aacttccagc agttgaattt ggcgggaaat cgtgtgagca gtgatggatg gcttgccttc
3361 atgggtgtat ttgagaatct taagcaatta gtgttttttg actttagtac taaagaattt
3421 ctacctgatc cagcattagt cagaaaactt agccaagtgt tatccaagtt aacttttctg
3481 caagaagcta ggcttgttgg gtggcaattt gatgatgatg atctcagtgt tattacaggt
3541 gcttttaaac tagtaactgc ttaaataaag tgtactcgaa g
//