LOCUS AF369794 5392 bp mRNA linear HUM 16-OCT-2001
DEFINITION Homo sapiens B cell crosslinked IgM-activating sequence protein
(BXMAS1) mRNA, complete cds.
ACCESSION AF369794
VERSION AF369794.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 4540 to 5295)
AUTHORS Nakayama,Y., Iwamoto,Y., Maher,S.E., Tanaka,Y. and Bothwell,A.L.
TITLE Altered gene expression upon BCR cross-linking in Burkitt's
lymphoma B cell line
JOURNAL Biochem. Biophys. Res. Commun. 277 (1), 124-127 (2000)
PUBMED 11027651
REFERENCE 2 (bases 1 to 5392)
AUTHORS Nakayama,Y., Weissman,S.M. and Bothwell,A.L.
TITLE BXMAS1 identifies a cluster of homologous genes differentially
expressed in B cells
JOURNAL Biochem. Biophys. Res. Commun. 285 (3), 830-837 (2001)
PUBMED 11453668
REFERENCE 3 (bases 1 to 5392)
AUTHORS Nakayama,Y., Weissman,S.M. and Bothwell,A.L.M.
TITLE Direct Submission
JOURNAL Submitted (11-APR-2001) Genetics, Yale University School of
Medicine, 295 Congress Ave., New Haven, CT 06510, USA
REFERENCE 4 (bases 1 to 5392)
AUTHORS Nakayama,Y., Weissman,S.M. and Bothwell,A.L.M.
TITLE Direct Submission
JOURNAL Submitted (01-JUN-2001) Genetics, Yale University School of
Medicine, 295 Congress Ave., New Haven, CT 06510, USA
REMARK Sequence update by submitter
COMMENT On Jun 1, 2001 this sequence version replaced AF369794.1.
FEATURES Location/Qualifiers
source 1..5392
/db_xref="H-InvDB:HIT000078540"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q21"
/note="derived from GenBank Accession Number AW755261"
gene 1..5392
/gene="BXMAS1"
CDS 159..3092
/gene="BXMAS1"
/note="immunoglobulin-like domain and ITIM
motif-containing receptor"
/codon_start=1
/product="B cell crosslinked IgM-activating sequence
protein"
/protein_id="AAK50059.2"
/translation="MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTC
KGFRFYSPQKTKWYHRYLGKEILRETPDNILEVQESGEYRCQAQGSPLSSPVHLDFSS
ASLILQAPLSVFEGDSVVLRCRAKAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKD
NGAYRCTGYKESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLE
RSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYWCKAATMPHSVISDSPRS
WIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVR
CERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIF
EGAKVTLHCEAQRGSLPILYQFHHEDAALERRSANSAGGVAISFSLTAEHSGNYYCTA
DNGFGPQRSKAVSLSITVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFY
HEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRP
ILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSL
TAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEA
LRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGPEAQRSEM
VTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSS
PSGGASLNLSLTAEHSGNYSCEADNGLGAQRSETVTLYITGLTANRSGPFATGVAGGL
LSIAGLAAGALLLYCWLSRKAGRKPASDPARSPPDSDSQEPTYHNVPAWEELQPVYTN
ANPRGENVVYSEVRIIQEKKKHAVASDPRHLRNKGSPIIYSEVKVASTPVSGSLFLAS
SAPHR"
misc_feature 210..464
/gene="BXMAS1"
/note="Region: immunoglobulin"
misc_feature 465..716
/gene="BXMAS1"
/note="Region: immunoglobulin C-2 type"
misc_feature 1002..1280
/gene="BXMAS1"
/note="domain 1"
misc_feature 1281..1559
/gene="BXMAS1"
/note="domain 2"
misc_feature 1560..1838
/gene="BXMAS1"
/note="domain 3"
misc_feature 1839..2117
/gene="BXMAS1"
/note="domain 4"
misc_feature 2118..2396
/gene="BXMAS1"
/note="domain 5"
misc_feature 2397..2672
/gene="BXMAS1"
/note="domain 6"
BASE COUNT 1276 a 1478 c 1328 g 1310 t
ORIGIN
1 aattcactaa tgcattctgc tctttttgag agcacagctt ctcagatgtg ctccttggag
61 ctggtgtgca gtgtcctgac tgtaagatca agtccaaacc tgttttggaa ttgaggaaac
121 ttctcttttg atctcagccc ttggtggtcc aggtcttcat gctgctgtgg gtgatattac
181 tggtcctggc tcctgtcagt ggacagtttg caaggacacc caggcccatt attttcctcc
241 agcctccatg gaccacagtc ttccaaggag agagagtgac cctcacttgc aagggatttc
301 gcttctactc accacagaaa acaaaatggt accatcggta cctcgggaaa gaaatactaa
361 gagaaacccc agacaatatc cttgaggttc aggaatctgg agagtacaga tgccaggccc
421 agggctcccc tctcagtagc cctgtgcact tggatttttc ttcagcttcg ctgatcctgc
481 aagctccact ttctgtgttt gaaggagact ctgtggttct gaggtgccgg gcaaaggcgg
541 aagtaacact gaataatact atttacaaga atgataatgt cctggcattc cttaataaaa
601 gaactgactt ccatattcct catgcatgtc tcaaggacaa tggtgcatat cgctgtactg
661 gatataagga aagttgttgc cctgtttctt ccaatacagt caaaatccaa gtccaagagc
721 catttacacg tccagtgctg agagccagct ccttccagcc catcagcggg aacccagtga
781 ccctgacctg tgagacccag ctctctctag agaggtcaga tgtcccgctc cggttccgct
841 tcttcagaga tgaccagacc ctgggattag gctggagtct ctccccgaat ttccagatta
901 ctgccatgtg gagtaaagat tcagggttct actggtgtaa ggcagcaaca atgcctcaca
961 gcgtcatatc tgacagcccg agatcctgga tacaggtgca gatccctgca tctcatcctg
1021 tcctcactct cagccctgaa aaggctctga attttgaggg aaccaaggtg acacttcact
1081 gtgaaaccca ggaagattct ctgcgcactt tgtacaggtt ttatcatgag ggtgtccccc
1141 tgaggcacaa gtcagtccgc tgtgaaaggg gagcatccat cagcttctca ctgactacag
1201 agaattcagg gaactactac tgcacagctg acaatggcct tggcgccaag cccagtaagg
1261 ctgtgagcct ctcagtcact gttcccgtgt ctcatcctgt cctcaacctc agctctcctg
1321 aggacctgat ttttgaggga gccaaggtga cacttcactg tgaagcccag agaggttcac
1381 tccccatcct gtaccagttt catcatgagg atgctgccct ggagcgtagg tcggccaact
1441 ctgcaggagg agtggccatc agcttctctc tgactgcaga gcattcaggg aactactact
1501 gcacagctga caatggcttt ggcccccagc gcagtaaggc ggtgagcctc tccatcactg
1561 tccctgtgtc tcatcctgtc ctcaccctca gctctgctga ggccctgact tttgaaggag
1621 ccactgtgac acttcactgt gaagtccaga gaggttcccc acaaatccta taccagtttt
1681 atcatgagga catgcccctg tggagcagct caacaccctc tgtgggaaga gtgtccttca
1741 gcttctctct gactgaagga cattcaggga attactactg cacagctgac aatggctttg
1801 gtccccagcg cagtgaagtg gtgagccttt ttgtcactgt tccagtgtct cgccccatcc
1861 tcaccctcag ggttcccagg gcccaggctg tggtggggga cctgctggag cttcactgtg
1921 aggccccgag aggctctccc ccaatcctgt actggtttta tcatgaggat gtcaccctgg
1981 ggagcagctc agccccctct ggaggagaag cttctttcaa cctctctctg actgcagaac
2041 attctggaaa ctactcatgt gaggccaaca atggcctagt ggcccagcac agtgacacaa
2101 tatcactcag tgttatagtt ccagtatctc gtcccatcct caccttcagg gctcccaggg
2161 cccaggctgt ggtgggggac ctgctggagc ttcactgtga ggccctgaga ggctcctccc
2221 caatcctgta ctggttttat catgaagatg tcaccctggg taagatctca gccccctctg
2281 gaggaggggc ctccttcaac ctctctctga ctacagaaca ttctggaatc tactcctgtg
2341 aggcagacaa tggtccggag gcccagcgca gtgagatggt gacactgaaa gttgcagttc
2401 cggtgtctcg cccggtcctc accctcaggg ctcccgggac ccatgctgcg gtgggggacc
2461 tgctggagct tcactgtgag gccctgagag gctctcccct gatcctgtac cggttttttc
2521 atgaggatgt caccctagga aataggtcgt ccccctctgg aggagcgtcc ttaaacctct
2581 ctctgactgc agagcactct ggaaactact cctgtgaggc cgacaatggc ctcggggccc
2641 agcgcagtga gacagtgaca ctttatatca cagggctgac cgcgaacaga agtggccctt
2701 ttgccacagg agtcgccggg ggcctgctca gcatagcagg ccttgctgcg ggggcactgc
2761 tgctctactg ctggctctcg agaaaagcag ggagaaagcc tgcctctgac cccgccagga
2821 gccctccaga ctcggactcc caagagccca cctatcacaa tgtaccagcc tgggaagagc
2881 tgcaaccagt gtacactaat gcaaatccta gaggagaaaa tgtggtttac tcagaagtac
2941 ggatcatcca agagaaaaag aaacatgcag tggcctctga ccccaggcat ctcaggaaca
3001 agggttcccc tatcatctac tctgaagtta aggtggcgtc aaccccggtt tccggatccc
3061 tgttcttggc ttcctcagct cctcacagat gagtccacac gtctctccaa ctgctgtttc
3121 agcctctgca ccccaaagtt ccccttgggg gagaagcagc attgaagtgg gaagatttag
3181 gctgccccag accatatcta ctggcctttg tttcacatgt cctcattctc agtctgacca
3241 gaatgcaggg ccctgctgga ctgtcacctg tttcccagtt aaagccctga ctggcaggtt
3301 ttttaatcca gtggcaaggt gctcccactc cagggcccag cacatctcct ggattcctta
3361 gtgggcttca gctgtgattg ctgttctgag tactgctctc atcacacccc cacagagggg
3421 gtcttaccac acaaagggag agtgggcctt caggagatgc cgggctggcc taacagctca
3481 ggtgctccta aactccgaca cagagttcct gctttgggtg gatgcatttc tcaattgtca
3541 tcagcctggt ggggctactg cagtgtgctg ccaaatggga cagcacacag cctgtgcaca
3601 tgggacatgt gatgggtctc cccacggggg ctgcatttca cactcctcca cctgtctcaa
3661 actctaaggt cggcacttga caccaaggta acttctctcc tgctcatgtg tcagtgtcta
3721 cctgcccaag taagtggctt tcatacacca agtcccaagt tcttcccatc ctaacagaag
3781 taacccagca agtcaaggcc aggaggacca ggggtgcaga cagaacacat actggaacac
3841 aggaggtgct caattactat ttgactgact gactgaatga atgaatgaat gaggaagaaa
3901 actgtgggta atcaaactgg cataaaatcc agtgcactcc ctaggaaatc cgggaggtat
3961 tctggcttcc ctaagaaaca acggaagaga aggagcttgg atgaggaaac tgttcagcaa
4021 gaggaagggc ttctcacact ttcatgtgct tgtggatcac ctgaggatcc tgtgaaaata
4081 cagatactga ttcagtgggt ctgtgtagag cctgagactg ccattctaac atgttcccag
4141 gggatgctga tgctgctggc cctgggactg cactgcatgc atgtgaagcc ctataggtct
4201 cagcagaggc ccatggagag ggaatgtgtg gctctggctg cccagggccc aactcggttc
4261 acacggatcg tgctgctccc tggccagcct ttggccacag caccaccagc tgctgttgct
4321 gagagagctt cttctctgtg acatgttggc tttcatcagc caccctggga agcggaaagt
4381 agctgccact atctttgttt ccccacctca ggcctcacac tttcccatga aaagggtgaa
4441 tgtatataac ctgagccctc tccattcaga gttgttctcc catctctgag caatgggatg
4501 ttctgttccg cttttatgat atccatcaca tcttatcttg atctttgctc ccagtggatt
4561 gtacagtgat gacttttaag ccccacggcc ctgaaataaa atccttccaa gggcattgga
4621 agctctctcc acctgaacca tggcttttca tgcttccaag tgtcagggcc ttgcccagat
4681 agacagggct gactctgctg ccccaacctt tcaaggagga aaccagacac ctgagacagg
4741 agcctgtatg cagcccagtg cagccttgca gaggacaagg ctggaggcat ttgtcatcac
4801 tacagatatg caactaaaat agacgtggag caagagaaat gcattcccac cgaggccgct
4861 tttttaggcc tagttgaaag tcaagaagga cagcagcaag cataggctca ggattaaaga
4921 aaaaaatctg ctcacagttt gttctggagg tcacatcacc aacaaagctc acgccctatg
4981 cagttctgag aaggtggagg caccaggctc aaaagaggaa atttagaatt tctcattggg
5041 agagtaaggt acccccatcc cagaatgata actgcacagt ggcagaacaa actccaccct
5101 aatgtgggtg gaccccatcc agtctgttga aggcctgagt gtaacaaaag ggcttattct
5161 tcctcaagta agggggaact cctgctttgg gctgggacat aagtttttct gctttcagac
5221 gcaaactgaa aaatggctct tcttgggtct tgagcttgct ggcatatgga ctgaaagaaa
5281 ctatgctatt ggatctcctg gatctccagc ttgctgactg cagatcttga gatatgtcag
5341 cctctacagt cacaagagct aattcattct aataaaccaa tctttctgta aa
//