LOCUS AF362910 6113 bp mRNA linear HUM 14-AUG-2002
DEFINITION Homo sapiens CAAX box protein TIMAP mRNA, complete cds.
ACCESSION AF362910
VERSION AF362910.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6113)
AUTHORS Cao,W., Mattagajasingh,S.N., Xu,H., Kim,K., Fierlbeck,W., Deng,J.,
Lowenstein,C.J. and Ballermann,B.J.
TITLE TIMAP, a novel CAAX box protein regulated by TGF-beta1 and
expressed in endothelial cells
JOURNAL Am. J. Physiol., Cell Physiol. 283 (1), C327-C337 (2002)
PUBMED 12055102
REFERENCE 2 (bases 1 to 6113)
AUTHORS Ballermann,B.J. and Cao,W.
TITLE Direct Submission
JOURNAL Submitted (21-MAR-2001) Medicine, Albert Einstein College of
Medicine, 1300 Morris Park Ave, Bronx, NY 10461, USA
FEATURES Location/Qualifiers
source 1..6113
/db_xref="H-InvDB:HIT000078399"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 53..1756
/note="contains five ankyrin repeats; similar to Homo
sapiens KIAA0823 protein encoded by AB020630"
/codon_start=1
/product="CAAX box protein TIMAP"
/protein_id="AAK52796.1"
/translation="MASHVDLLTELQLLEKVPTLERLRAAQKRRAQQLKKWAQYEQDL
QHRKRKHERKRSTGGRRKKVSFEASVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGL
TALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADL
LAVNSDGNMPYDLCEDEPTLDVIETCMAYQGITQEKINEMRVAPEQQMIADIHCMIAA
GQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQ
MAELLVSHGASLSARTSMDEMPIDLCEEEEFKVLLLELKHKHDVIMKSQLRHKSSLSR
RTSSAGSRGKVVRRASLSDRTNLYRKEYEGEAILWQRSAAEDQRTSTYNGDIRETRTD
QENKDPNPRLEKPVLLSEFPTKIPRGELDMPVENGLRAPVSAYQYALANGDVWKVHEV
PDYSMAYGNPGVADATPPWSSYKEQSPQTLLELKRQRAAAKLLSHPFLSTHLGSSMAR
TGESSSEGKAPLIGGRTSPYSSNGTSVYYTVTSGDPPLLKFKAPIEEMEEKVHGCCRI
S"
BASE COUNT 1437 a 1629 c 1669 g 1378 t
ORIGIN
1 ccccggtgca ccgtgctagc ccccagccag ggcgttgggg agggcggtgg ccatggccag
61 tcacgtggac ctgctgacgg agctgcagct gctggagaag gtgcccacgc tggagcggct
121 gcgggctgcc cagaagcgcc gggcccagca gctgaagaaa tgggcacagt acgagcagga
181 cttgcagcac cgcaagcgaa agcatgagcg gaagcgcagc acgggcggtc gccgcaagaa
241 agtgtccttc gaggccagcg tggccctgct ggaggcctcg ctgaggaacg acgccgagga
301 agtacgctac ttcctgaaga ataaggtcag ccctgatttg tgcaatgagg acggactcac
361 agccctacac cagtgctgca tcgacaactt tgaggaaatt gtgaagctgc tcctctccca
421 tggtgccaat gtgaacgcca aggacaacga gctgtggaca cctctccatg ctgcagccac
481 ctgcggccac atcaacctgg tgaagatcct cgttcagtat ggggccgact tgcttgctgt
541 caactcggat gggaacatgc catatgacct ctgcgaggat gaacccaccc tggatgtcat
601 cgagacctgc atggcatacc agggcatcac ccaagagaaa atcaacgaga tgcgggtggc
661 tcctgagcag cagatgattg cggacatcca ctgcatgatc gcagcgggcc aggacctgga
721 ctggatagat gcccagggtg ccacactgct gcacatagct ggagccaatg gatacctgcg
781 ggcagctgag ctcctcctgg atcatggagt gcgtgtggat gtgaaggact gggatggctg
841 ggagcccctg catgcagctg ccttctgggg acagatgcag atggcagagc tattggtgtc
901 ccatggagct agtctcagtg caaggacatc catggatgag atgccaatag acctgtgcga
961 ggaggaagag ttcaaggtcc tgctgctgga gctaaaacac aagcatgatg tgatcatgaa
1021 gtcacagctg aggcacaagt catccttgag ccggaggacc tccagcgcag gcagccgtgg
1081 gaaggtggtg cggcgagcca gcctgtcgga caggaccaac ctgtatagga aggagtatga
1141 gggagaggcc atcctgtggc agcggagtgc agctgaggat cagcggacct ccacctacaa
1201 cggggacatc agggagacca ggacagacca agagaataag gaccctaacc ccaggctgga
1261 gaagcccgtg ctactctccg aatttcctac caagatccca cgaggtgaac tggacatgcc
1321 tgttgagaat ggcctccggg ctccggtcag tgcctaccag tatgcgctgg ccaacgggga
1381 tgtctggaag gtgcatgagg tgcctgacta cagcatggcc tatggcaacc ctggcgtggc
1441 cgacgccacc ccgccctgga gcagctacaa ggaacagagc cctcagacgc ttctggagct
1501 gaagcggcag cgggctgcag ccaagctgct cagccacccc ttccttagca cacacctggg
1561 cagcagcatg gccaggacgg gcgagagtag cagtgaaggc aaggctccct tgatcggagg
1621 cagaacttca ccgtacagca gcaatgggac ctcggtatat tacacggtca ccagcggaga
1681 tcccccactc ttaaagttca aggcccccat agaggagatg gaggagaagg tgcatggctg
1741 ttgccgtatc tcctagtctc cgtgtgatgg aggagggaga tgcctgggga ggggctcctg
1801 gaatccaggc cagcccaaca accctggctg gggaggtgtc agggcagctg gggagaggtg
1861 ggctctgctt ttcagaggaa ctcagacccc agccctcagc tggctgccca tagcatccca
1921 tgtcccacgt cccgtggttc tgcttcctgc tgcatcgtct gccatctgac acaaggcctg
1981 tcgtggcctc ctggttcact ctgctgtctg atcttgggag ggtgggcttg agatcccagc
2041 tctattcttg gtataaaggc ttctccggat cagtacatgc atgtcacatt aacacacaca
2101 cacacacaca tatacacaca cacacaagct cgatcagtgt gtgtaggaat gacatacctg
2161 ggctcagggg aagcaagggg gcttagaatt tgtggggtat tcccaaaagg atggaagtta
2221 agactcagag tctcattacc actgccaatg tggttttagc aggggagggg acctgctaag
2281 ctgagaccca tagtcctgct cagagttatc ccaaagtctg agccaccagc cacacctgac
2341 aggggtgaga agtcctcgct gtgttcagag ggagccagga atctacatgg gtagatgaga
2401 tagacacaga cctgctcccc gcagccttgt tgagagccac acttctgccc atgccaggag
2461 ccagctgtgt gaccatccag gggtggaggg ggaaaaccag gcaatttcgt tcctggaatc
2521 aaccaaatca tgttttcctc ttggatggaa gtgtcaaagg cagaagggtg tgggaggggg
2581 acaaggtcag tatttaccaa agtgtatctg attttaaaaa ttcctttagt ctgtaaaact
2641 cctagaggga gggaggtaac tgaattcact tctttttgtg gatcgtatca aggtcactgg
2701 gttttactgg ctggtgctgg gaaaatgaag ctaagtgagg agcttccatt ggaatgcttt
2761 tccagggaga gaggccagtt aatttaaaaa aaacagtcgc tagttaacag cgacagagcc
2821 cagcaccctg gggtctttgt gaatatccag actgtttcag cccagcccat ctcagccaac
2881 cctccttaga ctgagctgtc agagcaagca attaggggcc agcctgcctc cacctcccac
2941 ccccttccac ctccatcagt catgtgtgca gagtcagtgc tcgggatccc gggcccagct
3001 tttgcctttt tggggatgct tggtgagaca gatttgccag tcagcccttt tgagttcccg
3061 cctcacccag gggctcccag cctgcacttg caggagtggt gatgccccaa gtctgcgaat
3121 ccagggtgca cgtggtcaat atcccctcct gcattcagga gagccatggt agggctggag
3181 ttgggtcttg cccagccctg cagtttcata gtcccagcct tcctggtgct ggggagggag
3241 gactgtgaat ggctgttctc ccctcactgc tgagtctccc aggaccccct ttggagatgc
3301 ccatggcatg ggcactgccc acaggctcag ccagaacctc ttggtgtacc cgataagctg
3361 caggttatcc cttgctctgt gcgcctttta tttgtcctta aactacctcc ttagagctct
3421 gaaggggtct cctagttcca gattttaatt tggggaacag atctgggttc tttttaaccc
3481 tcttctttct cagtctatga gaaacttgcc ctgaggggca cctgggctag gggcttggga
3541 ctggaagacc atccccgcct tgtgccacaa ctttggtcat gggatctgct ctttgtcatt
3601 cttagccccc tactgtggcc cccatagccc cataacccag agagggagct ggacttcagg
3661 gagcctgagt gatgctttcc caggagcagg gcagctggct ggaccagaaa gtagagggcc
3721 catgggagtg actgcaccct tggtggctgc tggaaaggga gaggttctca gcatcaggcc
3781 acctccaccc caatgccagg atagatgtat tctagagtag gggtggaggc ggcccaggag
3841 gctgaagaca ggtgcacaga tgcttcccac gaccttgcca tttggggtgg gctcttcaac
3901 atctcaggct gtggctggaa caggacagga tgatctaaaa cacacgtacc attggctgta
3961 aaacagtatg agcccagact gacgctgaaa tccctcatga gccaacctta gctacaaggt
4021 agggagttct gagggaagcc gcgtgctcct caggagagag ctgtttaggt tttccgatct
4081 ttttgctcag gggccaaaca ctgaaggcac gtactgccca acccactgag cgcctgaggc
4141 cattccctcc ttttccgcat gcctcctgcc tcctgggcta ttcctctcca cccagaaggc
4201 tgggaatccc agctgattcc ctgacaggag ccgacttcac acacaggtga ctctcaggca
4261 ttggctcatg ttttcagcca gggataaacc atcccttctt ggggctttaa gtccctgggg
4321 agctttccct gtaggtctcc tgggtgttga gagacaagtt ggagaccaac ctccaatgaa
4381 tgagccgcgg tcattcatta attcactcac gtaatttact gagtagctgc aacatgccag
4441 cctctacgtt aggttctgcg gataaaggag gaataagaca gagtcaggag aactgttcct
4501 tgtggtttcc gtcccttggg gaccacaggc atcagcagtc ccattcaagt cacctgaggc
4561 aaagtgtctg catcttcgtc cagcgaccct ttgcttttcg gctcctagaa tccttagagt
4621 ctgaattcct ttagctggga acagctgtca tggtcacccc tggataacat ttgccaccaa
4681 gtatagatgc tggatcttgg gttccaggca gacatcatcc aggtccatct ggaactttca
4741 gtgatagctg ccttcagcca gcatctttgg gggactctat aatagcagct tgagatcagt
4801 gtctagaaga ctgttctgca atttgctgcc aaatgcatct caggttttta aagtcattgt
4861 ttcttgctca tggtggctca tttattacat agtcccctca ccccactaat ggataatggg
4921 aggaaaagtt gctgcttcct tcagcatcaa agcctttcct tgggaatctg cctccctcca
4981 tggcaggggt ggattcggga gctgggagta accaggcaaa gtcaaccaga tgcctagctc
5041 ctgctgagac ccaggtccta tggcagctcc tcattagatt aaaggagacc acttccaaag
5101 caggtgctgc atggctcacc atcatatgcc ccaaacaact gaaagttggc ggttatcacc
5161 agactgtgag tttctggcaa gtagcttggg gaagctgaat aaactctagg cccagggcta
5221 ctaaagactt caggatagaa ttctccatca aatatacagc ataagtaaaa ctgctctgca
5281 ctgtttaatc catttccaag gggcttagaa aagctaacaa gggtgtgtcc cctgtcctgc
5341 cccaccggtt tgctggcttt gtaataacat aagaccattg tggttgttgg tgtcagatac
5401 cttcccatcc tgagctctct cacctacctg ctctctctcc tagagcagga tactggggta
5461 cttttaagaa gggtgctcct tttaagatgc ccagaaaagc tgtatttaac tcttgctatt
5521 tgtaacttgg ggatggtctc ccctgcccca gggcacataa gagcaaaggc tccaatggtc
5581 agtggatgac tctgcaaaag tgaccccctg tgccagaagc tatagccctc tccccaacag
5641 gtctctcttg ttggccagag ggcctgcttc ccatgggcat tgcaagtgcc accgtgcggg
5701 gcctggctct gcacacccag gaaaagtctg cagaccccca gccctccgca ataattcacc
5761 agaccagaag ccactggtgt acagagaaca cttaaaaaaa tgtattttat gtgaaaaaaa
5821 attaaaactc tgtatactgt atcagcagct ttgtgtaaaa atggcaatca agagagtcta
5881 atatatttaa aactttttta aaaaaaatct tcgcggatct ttgatatcgt actgaggtaa
5941 cttccacgta gccccttgcc acgcggcacc ggtgggcctt gggtccaaaa ctgtggctca
6001 gccacatccc aaagggggca catgtccctg gagttgcttc cagctgccaa ggcctgtgac
6061 agaattcgct gttaagagtt tttaattaaa attattaaat tccttttaat aac
//