LOCUS AF359380 1658 bp mRNA linear HUM 21-AUG-2001
DEFINITION Homo sapiens LANO adaptor protein (LANO) mRNA, complete cds.
ACCESSION AF359380
VERSION AF359380.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1658)
AUTHORS Saito,H., Santoni,M.J., Arsanto,J.P., Jaulin-Bastard,F., Le
Bivic,A., Marchetto,S., Audebert,S., Isnardon,D., Adelaide,J.,
Birnbaum,D. and Borg,J.P.
TITLE Lano, a novel LAP protein directly connected to MAGUK proteins in
epithelial cells
JOURNAL J. Biol. Chem. 276 (34), 32051-32055 (2001)
PUBMED 11440998
REFERENCE 2 (bases 1 to 1658)
AUTHORS Saito,H., Marchetto,S., Birnbaum,D. and Borg,J.-P.
TITLE Direct Submission
JOURNAL Submitted (12-MAR-2001) Molecular Oncology, U119 INSERM, 27,
Boulevard Lei Roure, Marseille 13009, France
FEATURES Location/Qualifiers
source 1..1658
/db_xref="H-InvDB:HIT000078336"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..1658
/gene="LANO"
CDS 1..1575
/gene="LANO"
/note="belongs to the LAP protein family with mammalian
Erbin, Scribble and Densin-180 but contains no PDZ domain;
interacts with MAGUKs (DLG) and LAP proteins (Erbin);
contains LRR motifs, a LAP specific domain (LAPSD), and a
C-terminal MAGUK PDZ domain binding site"
/codon_start=1
/product="LANO adaptor protein"
/protein_id="AAK72246.1"
/translation="MFHCIPLWRCNRHVESIDKRHCSLVYVPEEIYRYARSLEELLLD
ANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPESIS
FCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRE
NLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGN
LKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQN
RLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGC
CSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPLSLTALKLKALWLSDNQS
QPLLTFQTDTDYTTGEKILTCVLLPQLPSEPTCQENLPRCGALENLVNDVSDEAWNER
AVNRVSAIRFVEDEKDEEDNETRTLLRRATPHPGELKHMKKTVENLRNDMNAAKGLDS
NKNEVNHAIDRVTTSV"
BASE COUNT 483 a 383 c 378 g 414 t
ORIGIN
1 atgttccact gcatccccct gtggcggtgt aaccgtcatg tggagagcat cgacaagcgc
61 cactgctcgc tggtctacgt ccccgaggag atctaccgct atgcccggag cctggaggag
121 ctgctgctgg acgccaacca gctccgcgag ctgcccgagc aatttttcca gctagtcaaa
181 ttacgaaagc ttggacttag tgataatgaa attcagcggc tccctccaga aatagcaaac
241 ttcatgcagc tggtggaact agatgtgtct cgaaatgaga ttcctgaaat tccagaaagc
301 atttcattct gtaaagcact gcaggtagct gacttcagcg gaaacccact gactaggttg
361 ccagaaagct ttcctgaatt acagaattta acatgtcttt ctgtaaatga catctcacta
421 cagtctctac ctgaaaatat tggcaatctt tataacctgg cttcactgga actgagagag
481 aatcttctta catatcttcc tgactctctt acccagctgc gaagactaga agaacttgat
541 ttaggaaaca atgaaatata taatttgcca gaatcaattg gagccctctt acatctaaaa
601 gatctctggt tggatggaaa tcaactgtca gaattacctc aggaaatagg aaatctgaag
661 aacctgctgt gtttagatgt ctctgaaaac aggttggaaa gacttcctga agaaatcagt
721 ggcctgactt cattaacgga tttagtcatt tcccagaact tattagaaac gattccggat
781 ggcattggaa aactaaagaa actgtcaatc ttgaaggtgg atcagaatag actcacacag
841 ttgcctgaag cagttgggga atgtgaaagt ctcactgagt tagttcttac agaaaatcag
901 ctcctgaccc tgcctaaaag cattggaaaa ctaaagaagt tgagcaactt gaatgcagac
961 agaaataaat tagtgtcctt accaaaagag atcggcgggt gctgcagcct cactgtgttc
1021 tgtgtacgtg acaacagact aactcggata cctgcagagg tgtcacaggc aacagaactt
1081 catgtcctgg atgtggcagg gaacaggttg ctgcatctac ctttatccct gactgccttg
1141 aagttgaagg ctctgtggct atctgacaac cagtcccagc ccctgcttac attccagaca
1201 gacacagact acaccacagg agagaagatt ttaacctgtg tcttacttcc tcagctgcct
1261 tctgaaccta cttgtcaaga gaatctgcct cgctgtggtg cactggagaa cttggtaaat
1321 gatgtctctg atgaagcctg gaacgagcgt gctgtcaaca gagtcagtgc gatccgattt
1381 gtggaggatg agaaagatga agaagacaat gagacgagaa cacttctaag gcgagccact
1441 ccacacccag gggagttaaa gcacatgaaa aagacagtgg agaatttacg gaatgacatg
1501 aatgctgcta aaggactgga ctcaaacaaa aacgaggtca atcatgccat tgaccgagtg
1561 accacttctg tgtagagttt cacctccaag ttttacctcc tgtgtcttcc tctgctgtcg
1621 agacgttcct gtctgcttcc cgggagccaa tcactagt
//