LOCUS AF357881 3504 bp mRNA linear HUM 03-JUL-2001
DEFINITION Homo sapiens transcriptional coactivator MMS19 (MMS19) mRNA,
complete cds.
ACCESSION AF357881
VERSION AF357881.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3504)
AUTHORS Wu,X., Li,H. and Chen,J.D.
TITLE The human homologue of the yeast DNA repair and TFIIH regulator
MMS19 is an AF-1-specific coactivator of estrogen receptor
JOURNAL J. Biol. Chem. 276 (26), 23962-23968 (2001)
PUBMED 11279242
REFERENCE 2 (bases 1 to 3504)
AUTHORS Wu,X., Li,H. and Chen,J.D.
TITLE Direct Submission
JOURNAL Submitted (08-MAR-2001) Biochemistry and Molecular Pharmacology,
University of Massachusetts Medical School, 55 Lake Ave. North,
Worcester, MA 01655, USA
FEATURES Location/Qualifiers
source 1..3504
/db_xref="H-InvDB:HIT000078315"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
/map="10q24"
gene 1..3504
/gene="MMS19"
CDS 25..3117
/gene="MMS19"
/note="transcriptional coactivator for estrogen receptor;
similar to yeast DNA repair and TFIIH regulator MMS19"
/codon_start=1
/product="transcriptional coactivator MMS19"
/protein_id="AAK70402.1"
/translation="MAAAAAVEAAAPMGALWGLVHDFVVGQQEGPADQVAADVKSGNY
TVLQVVEALGSSLENPEPRTRARGIQLLSQVLLHCHTLLLEKEVVHLILFYENRLKDH
HLVIPSVLQGLKALSLCVALPPGLAVSVLKAIFQEVHVQSLPQVDRHTVYNIITNFMR
TREEELKSLGADFTFGFIHVMDGEKDPRNLLVAFRIVHDLISRDYSLGPFVEELFEVT
SCYFPIDFTPPPNDPHGIQREDLILSLRAVLASTPRFAEFLLPLLIEKVDSEVLSAKL
DSLQTLNACCAVYGQKELKDFLPSLWASIRREVFQTASERVEAEGLAALHSLTACLSR
SVLRADAEDLLDSFLSNILQDCRHHLCEPDMKLVWPSAKLLQAAAGASARACDSDTSN
VPPLLLEQFHKHSQSSQRRTILEMLLGFLKLQQKWSYEDKDQRPLNGFKDQLCSLVFM
ALTDPSTQLQLVGIRTLTVLGAQPDLLSYEDLELAVGHLYRLSFLKEDSQSCRVAALE
ASGTLAALYPVAFSSHLVPKLAEELRVGESNLTNGDEPTQCSRHLCCLQALSAVSTHP
SIVKETLPLLLQHLWQVNRGNMVAQSSDVIAVCQSLRQMAEKCQQDPESCWYFHQTAI
PCLLALAVQASMPEKEPSVLRKVLLEDEVLAAMVSVIGTATTHLSPELAAQSVTHIVP
LFLDGNVSFLPENSFPSRFQPFQDGSSGQRRLIALLMAFVCSLPRNVEIPQLNQLMRE
FLELSCCHSCPFSSTAAAKCFAGLLNKHPAGQQLDEFLQLAVDKVEAGLGSGPCRSQA
FTLLLWVTKALVLRYHPLSSCLTARLMGLLSDPELGPAAADGFSLLMSDCTDVLTRAG
HAEVRIMFRQRFFTDNVPALVQGFHAAPQDVKPNYLKGLSHVLNRLPKPVLLPELPTL
LSLLLEALSCPDCVVQLSTLSCLQPLLLEAPQVMSLHVDTLVTKFLNLSSSPSMAVRI
AALQCMHALTRLPTPVLLPYKPQVIRALAKPLDDKKRLVRKEAVSARGEWFLLGSPGS
"
BASE COUNT 753 a 969 c 922 g 860 t
ORIGIN
1 ctcccacggt ctctagttcg cgttatggcc gctgccgcgg ctgtggaggc ggcggcgcct
61 atgggtgccc tatggggcct cgtgcacgac ttcgtcgtgg gtcagcaaga gggccccgct
121 gaccaggtgg ctgcagatgt gaaatctggc aactatacag tgttacaagt tgtggaagcc
181 cttgggtcct ctctagagaa tccagaaccc cgaactcggg cacgaggaat ccagcttttg
241 tcacaggtgc tactccactg tcacaccttg ctcctggaga aggaagtggt acacctgata
301 ctgttctatg agaaccggct gaaggaccat catcttgtga tcccatctgt cctgcagggt
361 ttgaaggcac ttagcctgtg tgtggccctg cccccagggc tggctgtttc tgtgcttaaa
421 gccatcttcc aggaagtgca tgtacagtcc ctgccacagg tggaccgaca cacagtctac
481 aatatcatca ccaattttat gcgaacccgg gaagaagagc taaagagcct aggagctgac
541 ttcacctttg gcttcatcca tgtgatggat ggggaaaagg atccccgtaa tcttctggtg
601 gccttccgca tcgtccatga cctcatctcc agggactata gcctgggacc ctttgtggag
661 gagttgtttg aagtgacatc ctgttatttc cctatcgatt ttacccctcc acctaatgat
721 ccccatggta tccagagaga agacctcatc ctgagtcttc gcgctgtgct ggcttctaca
781 ccacgatttg ctgagtttct gctgcccctg ttgattgaga aagtggattc tgaggttctg
841 agtgccaagt tggattctct acagactctg aatgcttgct gtgctgtgta tggacagaag
901 gaactgaagg acttcctccc cagcctttgg gcttctatcc gcagagaggt gttccagacg
961 gcaagtgagc gggtggaggc agagggcctg gcggccctcc actccctgac tgcgtgtttg
1021 tctcgctctg tgctgagggc tgatgctgag gacctccttg actccttcct tagcaacatt
1081 ctacaggact gcagacacca cctgtgtgaa ccggacatga aactggtgtg gcctagtgcc
1141 aagctgttgc aggcagctgc aggtgcatct gcccgggcct gtgactctga caccagcaat
1201 gtaccgcctt tactgctgga acagttccac aagcacagtc agagcagcca gcggcggaca
1261 atccttgaaa tgctcctggg tttcttgaag ctgcagcaga aatggagcta tgaagacaaa
1321 gatcaaaggc ctctgaatgg cttcaaggac cagctgtgct cactggtatt catggctcta
1381 acagacccca gcacccagct tcagcttgtt ggcatccgta cactgacagt cttgggtgcc
1441 cagccagatc tcctatctta tgaggacttg gagctggcag tgggtcacct gtacagactg
1501 agcttcctga aggaggattc ccagagttgc agggtggcag cactggaagc atcaggaacc
1561 ctggctgctc tctaccctgt ggccttcagc agccacctcg tacccaagct cgctgaggag
1621 ctgcgtgtag gggagtcaaa tttgactaac ggagatgagc ccacccaatg ctcccggcat
1681 ctgtgctgtc tgcaagcctt gtcagctgta tcaacacatc ccagcatcgt caaggagaca
1741 ctgcctctgc tgctgcagca tctctggcaa gtgaacagag ggaatatggt tgcacaatcc
1801 agtgacgtta ttgctgtctg tcagagcctc agacagatgg cagaaaaatg tcagcaggac
1861 cctgagagtt gctggtattt ccaccagaca gctatacctt gcctgcttgc cttggctgtg
1921 caggcctcta tgccagagaa ggagccctca gttctgagaa aagtactatt ggaggatgag
1981 gtgttggctg ccatggtgtc tgtcattggc actgctacaa cccacctgag ccctgagtta
2041 gctgcccaga gtgtgacaca cattgtgccc ctcttcttgg atggcaacgt gtcctttctg
2101 cctgaaaaca gcttcccgag cagattccag ccattccagg atggctcctc agggcagagg
2161 cggctgattg cactgcttat ggcctttgtc tgctccctgc ctcgaaatgt ggaaatccct
2221 cagctgaacc aactcatgcg ggagtttttg gaactgagct gctgccacag ctgccccttt
2281 tcttccaccg ctgctgccaa gtgctttgca ggactcctca acaagcaccc tgcagggcag
2341 cagctggatg aattcctaca gctagctgtg gacaaagtgg aggctggcct gggctctggg
2401 ccttgtcgta gtcaggcctt cactcttctt ctctgggtaa caaaggccct agtgctcaga
2461 taccatcctc tcagctcctg ccttacagcc cggctcatgg gcctcctgag tgacccagaa
2521 ttaggtccag cagcagctga tggcttctct ctgctcatgt ctgactgcac tgatgtgctg
2581 actcgtgctg gccatgccga agtgcggatc atgttccgcc agcggttctt cacagataat
2641 gtgcctgctt tggtccaggg cttccatgct gctccccaag atgtgaagcc aaactacttg
2701 aagggtcttt ctcatgtact taacaggctg cccaagcctg tactcttgcc agagctgccc
2761 acgcttcttt ccttgctgct ggaggccctg tcctgccctg actgtgtggt gcagctctcc
2821 accctcagct gccttcagcc tcttctactg gaagcacccc aagtcatgag tcttcacgtg
2881 gacaccctcg tcaccaagtt tctgaacctc agctctagcc cttccatggc tgtccggatc
2941 gccgcactgc agtgcatgca tgctctcact cgcctgccca cccctgtgct gctgccgtac
3001 aaaccacagg tgattcgggc cttagccaaa cccctggatg acaagaagag actggtgcgc
3061 aaggaagcag tgtcagccag aggggagtgg tttctgttgg ggagccctgg cagctgagcc
3121 ctcagtcctg gcctagactg ttctgacaat ctaacctggg attactaact gttgagccat
3181 cttccccaaa gcagggaaac cactggtctc tgactgcctt tcccacagac acagcacaaa
3241 tgctaggcct ctgttgcatg gctgtacaaa gaacataaga gtccatattt ctagtggatt
3301 tgtaaaataa gtgtgtgtga gacacttgcg tttgaagaaa gatctagggt cctgggtctc
3361 ttgcatttat atgtcagaaa aggggcgata tgctgctgag gggtgagtgc atatgagtgt
3421 ggccctgagg accagggctg gcagatgttg tctacctgct gaagaataaa gatttctttt
3481 ggtaaaaaaa aaaaaaaaaa aaaa
//