LOCUS AF354655 1540 bp mRNA linear HUM 06-SEP-2001
DEFINITION Homo sapiens PUMA beta mRNA, complete cds.
ACCESSION AF354655
VERSION AF354655.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1540)
AUTHORS Nakano,K. and Vousden,K.H.
TITLE PUMA, a novel proapoptotic gene, is induced by p53
JOURNAL Mol. Cell 7 (3), 683-694 (2001)
PUBMED 11463392
REFERENCE 2 (bases 1 to 1540)
AUTHORS Nakano,K. and Vousden,K.H.
TITLE Direct Submission
JOURNAL Submitted (01-MAR-2001) Regulation of Cell Growth Laboratory, NCI
at Frederick, Building 560, Room 22-96, 1050 Boyles Street,
Frederick, MD 21702-1201, USA
FEATURES Location/Qualifiers
source 1..1540
/db_xref="H-InvDB:HIT000078268"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="19p13"
/cell_line="U2OS"
/cell_type="osteosarcoma"
CDS 165..560
/note="PUMA transcript 2"
/codon_start=1
/product="PUMA beta"
/protein_id="AAK39543.1"
/translation="MKFGMGSAQACPCQVPRAASTTWVPCQICGPQPSLSLAEQHLES
PVPSAPGALAGGPTQAAPGVRGEEEQWAREIGAQLRRMADDLNAQYERRRQEEQQRHR
PSPWRVLYNLIMGLLPLPRGHRAPEMEPN"
BASE COUNT 301 a 445 c 524 g 270 t
ORIGIN
1 gaggcgattg cgattgggtg agacccagta aggatggaaa gtgtagagga gacaggaatc
61 cacggctttg gaaaaaggaa ggacaaaact caccaaacca gagcagggca ggaagtaaca
121 atgagaaact gaaaaagaaa cggaatggaa agctatgaga caggatgaaa tttggcatgg
181 ggtctgccca ggcatgtcca tgccaggtgc ccagggctgc ttccacgacg tgggtcccct
241 gccagatttg tggtcctcag ccctcgctct cgctggcgga gcagcacctg gagtcgcccg
301 tgcccagcgc cccgggggct ctggcgggcg gtcccaccca ggcggccccg ggagtccgcg
361 gggaggagga acagtgggcc cgggagatcg gggcccagct gcggcggatg gcggacgacc
421 tcaacgcaca gtacgagcgg cggagacaag aggagcagca gcggcaccgc ccctcaccct
481 ggagggtcct gtacaatctc atcatgggac tcctgccctt acccaggggc cacagagccc
541 ccgagatgga gcccaattag gtgcctgcac ccgcccggtg gacgtcaggg actcgggggg
601 caggcccctc ccacctcctg acaccctggc cagcgcgggg gactttctct gcaccatgta
661 gcatactgga ctcccagccc tgcctgtccc gggggcgggc cggggcagcc actccagccc
721 cagcccagcc tggggtgcac tgacggagat gcggactcct gggtccctgg ccaagaagcc
781 aggagaggga cggctgatgg actcagcatc ggaaggtggc ggtgaccgag ggggtgggga
841 ctgagccgcc cgcctctgcc gcccaccacc atctcaggaa aggctgttgt gctggtgccc
901 gttccagctg caggggtgac actggggggg gggggggctc tcctctcggt gctccttcac
961 tctgggcctg gcctcaggcc cctggtgctt ccccccctcc tcctgggagg gggcccgtga
1021 agagcaaatg agccaaacgt gaccactagc ctcctggagc cagagagtgg ggctcgtttg
1081 ccggttgctc cagcccggcg cccagccatc ttccctgagc cagccggcgg gtggtgggca
1141 tgcctgcctc accttcatca gggggtggcc aggaggggcc cagactgtga atcctgtgct
1201 ctgcccgtga ccgccccccg ccccatcaat cccattgcat aggtttagag agagcacgtg
1261 tgaccactgg cattcatttg gggggtggga gattttggct gaagccgccc cagccttagt
1321 ccccagggcc aagcgctggg gggaagacgg ggagtcaggg agggggggaa atctcggaag
1381 agggaggagt ctgggagtgg ggagggatgg cccagcctgt aagatactgt atatgcgctg
1441 ctgtagatac cggaatgaat tttctgtaca tgtttggtta attttttttg tacatgattt
1501 ttgtatgttt ccttttcaat aaaatcagat tggaacagtg
//