LOCUS AF354654 1829 bp mRNA linear HUM 06-SEP-2001
DEFINITION Homo sapiens PUMA alpha mRNA, complete cds.
ACCESSION AF354654
VERSION AF354654.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1829)
AUTHORS Nakano,K. and Vousden,K.H.
TITLE PUMA, a novel proapoptotic gene, is induced by p53
JOURNAL Mol. Cell 7 (3), 683-694 (2001)
PUBMED 11463392
REFERENCE 2 (bases 1 to 1829)
AUTHORS Nakano,K. and Vousden,K.H.
TITLE Direct Submission
JOURNAL Submitted (01-MAR-2001) Regulation of Cell Growth Laboratory, NCI
at Frederick, Building 560, Room 22-96, 1050 Boyles Street,
Frederick, MD 21702-1201, USA
FEATURES Location/Qualifiers
source 1..1829
/db_xref="H-InvDB:HIT000078267"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="19p13"
/cell_line="U2OS"
/cell_type="osteosarcoma"
misc_feature 165..950
/note="putative PUMA gamma coding region"
CDS 268..849
/note="PUMA transcript 1"
/codon_start=1
/product="PUMA alpha"
/protein_id="AAK39542.1"
/translation="MARARQEGSSPEPVEGLARDGPRPFPLGRLVPSAVSCGLCEPGL
AAAPAAPTLLPAAYLCAPTAPPAVTAALGGSRWPGGPRSRPRGPRPDGPQPSLSLAEQ
HLESPVPSAPGALAGGPTQAAPGVRGEEEQWAREIGAQLRRMADDLNAQYERRRQEEQ
QRHRPSPWRVLYNLIMGLLPLPRGHRAPEMEPN"
BASE COUNT 322 a 588 c 619 g 300 t
ORIGIN
1 gaggcgattg cgattgggtg agacccagta aggatggaaa gtgtagagga gacaggaatc
61 cacggctttg gaaaaaggaa ggacaaaact caccaaacca gagcagggca ggaagtaaca
121 atgagaaact gaaaaagaaa cggaatggaa agctatgaga caggatgaaa tttggcatgg
181 ggtctgccca ggcatgtcca tgccaggtgc ccagggctgc ttccacgacg tgggtcccct
241 gccagatttg tggccccagg gagcgccatg gcccgcgcac gccaggaggg cagctccccg
301 gagcccgtag agggcctggc ccgcgacggc ccgcgcccct tcccgctcgg ccgcctggtg
361 ccctcggcag tgtcctgcgg cctctgcgag cccggcctgg ctgccgcccc cgccgccccc
421 accctgctgc ccgctgccta cctctgcgcc cccaccgccc cacccgccgt caccgccgcc
481 ctggggggtt cccgctggcc tgggggtccc cgcagccggc cccgaggccc gcgcccggac
541 ggtcctcagc cctcgctctc gctggcggag cagcacctgg agtcgcccgt gcccagcgcc
601 ccgggggctc tggcgggcgg tcccacccag gcggccccgg gagtccgcgg ggaggaggaa
661 cagtgggccc gggagatcgg ggcccagctg cggcggatgg cggacgacct caacgcacag
721 tacgagcggc ggagacaaga ggagcagcag cggcaccgcc cctcaccctg gagggtcctg
781 tacaatctca tcatgggact cctgccctta cccaggggcc acagagcccc cgagatggag
841 cccaattagg tgcctgcacc cgcccggtgg acgtcaggga ctcggggggc aggcccctcc
901 cacctcctga caccctggcc agcgcggggg actttctctg caccatgtag catactggac
961 tcccagccct gcctgtcccg ggggcgggcc ggggcagcca ctccagcccc agcccagcct
1021 ggggtgcact gacggagatg cggactcctg ggtccctggc caagaagcca ggagagggac
1081 ggctgatgga ctcagcatcg gaaggtggcg gtgaccgagg gggtggggac tgagccgccc
1141 gcctctgccg cccaccacca tctcaggaaa ggctgttgtg ctggtgcccg ttccagctgc
1201 aggggtgaca ctgggggggg ggggggctct cctctcggtg ctccttcact ctgggcctgg
1261 cctcaggccc ctggtgcttc cccccctcct cctgggaggg ggcccgtgaa gagcaaatga
1321 gccaaacgtg accactagcc tcctggagcc agagagtggg gctcgtttgc cggttgctcc
1381 agcccggcgc ccagccatct tccctgagcc agccggcggg tggtgggcat gcctgcctca
1441 ccttcatcag ggggtggcca ggaggggccc agactgtgaa tcctgtgctc tgcccgtgac
1501 cgccccccgc cccatcaatc ccattgcata ggtttagaga gagcacgtgt gaccactggc
1561 attcatttgg ggggtgggag attttggctg aagccgcccc agccttagtc cccagggcca
1621 agcgctgggg ggaagacggg gagtcaggga gggggggaaa tctcggaaga gggaggagtc
1681 tgggagtggg gagggatggc ccagcctgta agatactgta tatgcgctgc tgtagatacc
1741 ggaatgaatt ttctgtacat gtttggttaa ttttttttgt acatgatttt tgtatgtttc
1801 cttttcaata aaatcagatt ggaacagtg
//