LOCUS AF347693 7888 bp mRNA linear HUM 12-AUG-2003
DEFINITION Homo sapiens multiple asters 1 (MAST1) mRNA, complete cds.
ACCESSION AF347693
VERSION AF347693.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7888)
AUTHORS Maiato,H., Sunkel,C.E. and Earnshaw,W.C.
TITLE Full length cDNA of a human homologue of Drosophila melanogaster
multiple asters (MAST) gene
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7888)
AUTHORS Maiato,H., Sunkel,C.E. and Earnshaw,W.C.
TITLE Direct Submission
JOURNAL Submitted (08-FEB-2001) ICMB, University of Edinburgh, Mayfield
Road, Edinburgh EH9 3JR, Scotland, UK
FEATURES Location/Qualifiers
source 1..7888
/db_xref="H-InvDB:HIT000242913"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2q14.3"
gene 1..7888
/gene="MAST1"
CDS 166..4782
/gene="MAST1"
/note="centrosomal; similar to Drosophila melanogaster
multiple asters (MAST) required for centrosome separation
and organization of bipolar spindle"
/codon_start=1
/product="multiple asters 1"
/protein_id="AAQ15051.1"
/translation="MEPRMESCLAQVLQKDVGKRLQVGQELIDYFSDKQKSADLEHDQ
TMLDKLVDGLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGD
AKDSVREQDQTLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGA
QTLTLSKIVPHICNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNV
IFTKFDEVQKSGNMIQSANDKNFDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTR
RLGSSTLGSKSSAAKEGAGAVDEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDD
KHDWEQRVNALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITL
GHLSSVLGNKFDHGAEAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRLIPVIT
SNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIEARK
CYWGFHSHFSREAEHLYHTLESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRP
LSAKRSPTGSTTSRASTVSTKSVSTTGSLQRSRSDIDVNAAASAKSKVSSSSGTTPFS
SAAALPPGSYASLGRIRTRRQSSGSATNVASTPDNRGRSRAKVVSQSQRSRSANPAGA
GSRSSSPGKLLGSGYGGLTGGSSRGPPVTPSSEKRSKIPRSQGCSRETSPNRIGLARS
SRIPRPSMSQGCSRDTSRESSRDTSPARGFPPLDRFGLGQPGRIPGSVNAMRVLSTST
DLEAAVADALKKPVRRRYEPYGMYSDDDANSDASSVCSERSYGSRNGGIPHYLRQTED
VAEVLNHCASSNWSERKEGLLGLQNLLKSQRTLSRVELKRLCEIFTRMFADPHSKRVF
SMFLETLVDFIIIHKDDLQDWLFVLLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPF
DQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFVNSSETRLAVSRIITW
TTEPKSSDVRKAAQIVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNTS
VGSPSNTIGRTPSRHTSSRTSPLTSPTNCSHGGLSPSRLWGWSADGLAKHPPPFSQPN
SIPTAPSHKALRRSYSPSMLDYDTENLNSEEIYSSLRGVTEAIEKFSFRSQEDLNEPI
KRDGKKECDIVSRDGGAASPATEGRGGSEVEGGRTALDNKTSLLNTQPPRAFPGPRAR
DYNPYPYSDAINTYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELSNHNERVEE
RKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIRALALRVLREILRNQP
ARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADY
PINLAAIKMQTKVVERIAKESLLQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIYSV
IGEDLKPHLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS"
BASE COUNT 2129 a 1876 c 1858 g 2025 t
ORIGIN
1 cagacacaca tggtgcattg ttgccattcc ccagattgca tctttgaaac acaggctctt
61 agtaaccttc agcgaacaaa gaggcaacct cccagatacg tctgctggga gggagtcatc
121 gtgactgccc tctagctttt gctggatctg gatttgaatt ccactatgga gcctcgcatg
181 gagtcctgcc tggcgcaggt gttgcagaag gatgtgggga aacgattgca ggttggccaa
241 gaactgatag actatttctc agacaaacag aagtctgctg accttgagca tgaccagacc
301 atgttagata aacttgtgga tggacttgct acctcttggg tgaactctag caattacaag
361 gtggttctgc tgggcatgga catcctgtcc gccctggtga cccggctgca ggatcggttc
421 aaggcgcaga tcggcacagt gctgccaagt ctaatagaca gactaggaga tgctaaagac
481 tctgtgaggg agcaggacca aactctgctg ctaaagatca tggatcaagc tgctaatccc
541 cagtacgtat gggacagaat gcttggaggc ttcaaacaca agaatttccg tactcgagaa
601 ggcatctgtc tctgccttat agcaacactc aatgcctctg gagcacagac tttaacacta
661 agcaagattg tgccacatat atgcaactta cttggagatc caaacagcca ggttcgagat
721 gcagcaataa acagcttagt ggaaatttac agacatgtag gagaacgtgt gagggcagat
781 ctcagtaaaa aaggattgcc acagtcccgg ttgaatgtaa tttttacaaa atttgatgaa
841 gtccagaaat ctggaaacat gatacaatct gcaaatgata aaaatttcga cgatgaagat
901 tctgtggatg gtaacagacc ttcctctgct agttctacat catccaaggc tccaccaagt
961 tctcggagaa acgttggaat gggaaccacc cgccggcttg gttcatccac ccttggatcc
1021 aagtcttcag ctgcaaaaga aggagctggt gctgttgatg aagaggattt tattaaagca
1081 tttgatgatg tacctgtagt acagatttat tccagccgag accttgagga atccataaac
1141 aaaattaggg aaatattatc tgatgacaag catgattggg agcagagagt aaatgctcta
1201 aaaaagatta gatctttact tttggctggt gctgctgagt atgataactt ctttcaacat
1261 ttgcgtcttt tggatggagc ctttaaactc tctgctaagg acctgcggtc tcaggtagtg
1321 cgggaggctt gtatcacgtt ggggcatctg tcatcagttc tggggaataa gtttgaccat
1381 ggagctgaag ccattatgcc aactatcttt aatttaattc caaacagtgc caaaattatg
1441 gccacatctg gtgttgtagc tgttaggtta attattcggc acacacacat ccctaggtta
1501 atacctgtca taacaagcaa ctgtacctct aagtctgtcg cagttagaag gcgctgtttt
1561 gaatttttag atttgctttt acaagaatgg cagacacatt cactagaacg acacatatca
1621 gtattagctg aaacaataaa gaagggaata catgatgctg attccgaagc aagaatagaa
1681 gccagaaaat gttactgggg tttccacagt cacttcagca gagaagcaga gcacttgtac
1741 cacaccttgg agtcctccta ccagaaagcc ctgcagtccc acctgaagaa ctcagacagc
1801 atagtgtctc tgcctcagtc agaccgctca tcttccagct ctcaagagag tctaaatcgt
1861 ccgctgtctg ccaaaagaag tcctactgga agtaccacat ctagagcttc tacagttagt
1921 accaaatctg tgtcaacgac tgggtccctc cagcgatctc gaagtgatat tgatgtgaac
1981 gcagcagcca gtgccaaatc caaagtctcc tcatcttcgg gcacgacgcc tttcagctct
2041 gcagcagctt tgcctccagg gtcatacgca tccttaggtc ggatccgcac aagacggcaa
2101 agctctggga gtgccaccaa cgtcgcctct acacctgata accggggccg cagtcgcgct
2161 aaagtggttt cacagtccca gcgatccaga tctgctaatc ctgctggtgc tggcagccgg
2221 tcaagttccc caggaaaatt gttgggaagt ggttatggtg gacttactgg gggctcctca
2281 cgaggcccac ctgtgacacc gtcttcagaa aagcgaagca agattcccag gagccaggga
2341 tgtagccggg aaacaagtcc aaaccgaata ggattagcac ggagcagccg tatccctcga
2401 cccagcatga gtcaggggtg cagccgcgat accagccgtg agagcagccg agatacaagc
2461 cctgctcggg gctttcctcc acttgatcgg tttgggcttg gccagccagg aagaatacct
2521 ggttctgtga atgccatgag agttctgagc acaagtacag atcttgaagc tgctgttgct
2581 gatgctttga agaagcctgt gaggaggaga tatgagccgt atgggatgta ttctgacgat
2641 gatgccaaca gtgatgcctc aagtgtttgc tctgagcgct catatggctc caggaatggt
2701 ggcattcccc attatctgcg gcagactgag gatgtagcag aagttctcaa ccactgtgct
2761 agttcaaact ggtcagaaag gaaagaaggg cttctgggcc tgcagaactt actgaagagc
2821 caaagaacac tgagtcgagt tgaactgaaa aggttgtgtg agatcttcac tcggatgttt
2881 gctgaccctc atagcaagag agttttcagt atgtttttgg agactcttgt ggattttata
2941 ataattcata aggatgattt acaagactgg ctttttgttc ttctcacaca attacttaag
3001 aaaatgggag cagatttact tggatctgtg caagcaaaag ttcaaaaggc tctagatgtc
3061 acaagggact cctttccatt tgatcaacaa tttaacattt tgatgagatt tattgtggat
3121 caaactcaaa ctccaaacct caaggtcaaa gttgcaatcc tgaaatacat tgagtctctg
3181 gccagacaga tggatccaac agattttgta aactctagtg agacaaggct tgctgtttct
3241 agaatcataa cctggacaac agaaccaaag agttcagacg tgagaaaggc agcacagatt
3301 gtgctaatct ctctgtttga attgaatact cctgaattta ccatgttact tggtgccttg
3361 ccaaaaacat tccaggatgg tgccaccaaa ctcctgcaca accacctcaa gaattccagt
3421 aacaccagtg tgggctctcc aagcaatacg attggccgga cgccctcccg acacaccagc
3481 agcaggacca gccccctgac ctcacccacc aactgttccc atgggggtct gtctccaagt
3541 cggttatggg gttggagtgc cgacgggtta gcgaagcacc cacctccctt ttctcagcct
3601 aactccatcc ccaccgctcc ctcccacaag gctctcaggc gctcttactc tcccagcatg
3661 ctggactatg atacagagaa cctgaactct gaagaaatct atagttctct acgtggagtt
3721 acagaagcca ttgaaaagtt tagttttcga agccaagaag atctgaatga gccaattaaa
3781 cgagatggca aaaaggagtg tgatattgtg tcccgcgatg ggggcgctgc ctcccctgcc
3841 actgagggcc gggggggtag tgaagtagaa ggaggccgga cagctctgga taacaagacc
3901 tcactactca acacccagcc tccgcgcgcc ttcccggggc cgcgggcgcg agactacaac
3961 ccgtacccct actcagatgc catcaacacc tacgacaaga ccgccctgaa agaggctgtg
4021 ttcgatgacg acatggagca gcttcgagac gtgcccatcg accattctga cctggtggct
4081 gaccttctga aagagctgtc caaccacaat gagcgagtgg aggaacggaa gggagccctg
4141 ctggagctgc tcaagatcac gcgggaagac agccttggtg tctgggagga gcacttcaag
4201 accattctgc tcctgctgct ggagaccctt ggagacaaag accattcaat tcgagcactg
4261 gcgttaagag ttttgaggga aattctgaga aatcaaccag caagatttaa aaactacgcc
4321 gagctgacga ttatgaagac tctggaagcc cacaaagact cccataagga ggtggtgaga
4381 gcggctgagg aggctgcgtc cacactggcc agttccatcc acccggagca gtgcatcaag
4441 gtgctctgcc ccatcatcca gacggccgac taccccatca accttgctgc catcaagatg
4501 cagaccaaag tcgtcgagag gatcgcaaag gagtcattgc tgcagctcct tgtcgacatc
4561 atcccaggct tgctgcaggg ttatgacaac accgaaagta gtgtgcgtaa ggccagcgtg
4621 ttttgcttag tggcaattta ttccgtaatc ggagaagacc tgaaacctca ccttgcacag
4681 ctcacaggga gcaagatgaa gctactaaac ttatacataa agagggccca gaccaccaac
4741 agcaacagca gctcctcctc cgatgtctcc acgcacagct aatggcagta cctgtctctt
4801 gtgtagacct agaagcaatc ggtggtgcct ctcagagacc tttccccacc cccttcatcg
4861 gctgcccagt cagtacaagg aggcccacaa atatttatta caatcagtat tttggtccct
4921 tccagctttt ctgtagaatc ttactggtat tgaatgtaaa ggaagcaagg cctgtattgc
4981 agtcttcata caaaacaaaa ggaataagaa cagaaaagag ccatactgaa acatgtcttg
5041 tacagcctgc tgagatggcg aaaccctgtg tgtggggtgc agtttttaaa aatcagagcg
5101 ctctagccac tacttggtag aaagtagcat tttttttttc agttaataac atatttgggg
5161 gtggggtggg gtgttacttt gtgttcttcc tccttagcct attttcttgt gcgtatggtc
5221 tgtgtggggc ccctttcaca gctgacacca cgaaaggtga tatatcttta agttgtgttc
5281 tgagacctac taaaaatggg aatcaagtct tggcaagaac agtctgaaga tggcctttta
5341 acaaacgctg ggaattttgc ttgtcatatc cagactggag gccgactgcc ctggctttca
5401 gcgtagaatt gggagtgcac cctgacagtc tccttccagc tctccctaat cgactccacc
5461 gacaaggtcc ctaccccaga gcttccatgc aaaggaattc ttcaagttta aatctggaca
5521 caaaaataag ataaatgtat ggcatcattt agggatgcct gagatggcag ttcatgaagc
5581 acagaagata aagaagaagt ctttcatctt tactgctgag atccttggga acactgttgt
5641 catgggggct ctgccaagac cctcatctct gggctacacg gtgattcaga ttgagcacca
5701 acttgtttcc tcccctcaaa gttctgccta agccgttcag ttctaacatg gtctcagtta
5761 atctggtaaa tggcatcttt accatcttag ttctgacttc tcagtttaat gtgggattaa
5821 gagccaagaa aagcctagag agactggata tcacaatttt ttttaatttt ataaactgaa
5881 gtagttcctt gaatgtctgt tgatgaaata gtcactgttt aaggaaaaaa gtaattatga
5941 ggtgtagcag attgcagaaa aacaggatta gaaacacact taaaaagaac acacatttag
6001 agtctctctt cctcctcagc gaaccactag gccccctttt ttaaaaacac ctttagagcc
6061 taattactcc aataaaagta actagaggtt tggagtctgg ttaaataaat tctgagtaaa
6121 attcttaagc caaatggaaa ttcttaatgc aatcatgagg acttctattg tctcttactg
6181 ttgtattaga tcctataaat tgaactgatt tttccataag gaaaatgctt cttttgagat
6241 taattctaat aacgtatttg ctattgcagt gcagagccca ctgcaactgc taggactgaa
6301 agcagaggct gggtgccaga gcacgtgatt cttaacatca tttccacaga cccctctgcc
6361 ctgaccctct gcattggatg caggaagctg ggaaagactg atgttgattt ggaaacatgg
6421 gctgaaaatg aaggccccat agtgcatagg aacagtaaag ccagggtgct gacgtgtgtg
6481 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg gtgttgtgtg tgtttgtgcg tgcaccctac
6541 acatgtgtgg tacctcactg ctgctgttta gggaacttga gggacgcgtt tcaaggggtt
6601 gggtattact gacgagcttt ggctcaaaat atagcaggac caggtctttt gttgataagt
6661 actgtttgtt tattaatatg tcattaatgg tatttctttt ttacactcta caagtgaatt
6721 agggagtctc ttgttgaccc ctttgttgca ggaatgtgcg tcgggctagg ttatccatga
6781 gtttctttat tcctaatgca gttagaaaga cctttctcct tgagctcttt gactcccaga
6841 aggtacccca gtccccagtg tacttagaaa ggatctcgaa cattgctgga cgtcctcata
6901 gtactcacaa agggctagcc ttgaatgtca ctcgcccagt cttcagtctc ctgacttaga
6961 gatacaatca cgtcacaggt ctcttggcct caatctgaaa actgctgccg ccgcgccgag
7021 gagactcgca tgccgccacc acctcactgg gagggcgccg agcccaccgt cgccccctag
7081 accctgacag ctgcagctgc cttgccttgc cgccgcctcc ctgcagggcc cctgttccaa
7141 tgaaaaacag aacacaaaag agcagagcac ctaagcctgt ctctgcctcc ctgtctaccg
7201 gactggccag ggcccaagac ccccgctgct ccactgcggg gctgggcggg ctgactccct
7261 gcttcctcca agctgctgcc tcccctgcag ccagggtctg ggcagggtgc agccggtcct
7321 cggggcacgc agcttccttc aagtacactg tgtgtgcttc ccggacctgc ggcgatgcca
7381 cgggcctgcc ttttctatgc gcctcactag cttaccaccc tgtgcaggta atgcaactga
7441 ctttgtctca tcagtctttt tctttccctg ccacccttta tttatcaagc gtaatgttac
7501 actttaaagg acagcaaata agaactttgt agaatcccac caggactttg ctaacaataa
7561 tgtttggaaa taaagaagtg ctctgaaaaa atatcagcca ccaaaatagt tatgttggca
7621 ctgtgttcac acgcatggtc cccacacccc caggttgggt gggttttttt gttttttggg
7681 tttttttggg gggggggctt tttcatgtta catccatatc tgtatttata tcttatttgt
7741 ttcactttca agtgtatcat ggcaaatgta cagatttttt tgttaataat gtgctaggat
7801 ttgctaaaaa agaaaaaaaa aaaacccttt tgagtttgcc ctagaataaa tgagacttaa
7861 tttaaaaaaa aaaaaaaaaa aaaaaaaa
//