LOCUS AF343664 5321 bp mRNA linear HUM 18-JUN-2001
DEFINITION Homo sapiens immunoglobulin superfamily receptor translocation
associated protein 2c (IRTA2) mRNA, complete cds, alternatively
spliced.
ACCESSION AF343664
VERSION AF343664.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5321)
AUTHORS Hatzivassiliou,G., Miller,I.J., Takizawa,J., Palanisamy,N.,
Rao,P.H., Iida,S., Tagawa,S., Taniwaki,M., Russo,J.J., Neri,A.,
Cattoretti,G., Clynes,R., Mendelsohn,C., Chaganti,R.S.K. and
Dalla-Favera,R.
TITLE IRTA1 and IRTA2, novel immunoglobulin superfamily receptors
expressed in B cells and involved in chromosome 1q21 abnormalities
in B cell malignancy
JOURNAL Immunity 14 (3), 277-289 (2001)
PUBMED 11290337
REFERENCE 2 (bases 1 to 5321)
AUTHORS Hatzivassiliou,G., Miller,I.J., Takizawa,J., Russo,J.J. and
Dalla-Favera,R.
TITLE Direct Submission
JOURNAL Submitted (30-JAN-2001) Pathology and Institute of Cancer Genetics,
Columbia University, 1150 St. Nicholas Avenue, New York, NY 10032,
USA
FEATURES Location/Qualifiers
source 1..5321
/db_xref="H-InvDB:HIT000078083"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q21.2-q22"
/tissue_type="spleen"
gene 1..5321
/gene="IRTA2"
CDS 94..3027
/gene="IRTA2"
/note="IRTA2c; immunoglobulin superfamily receptor;
transmembrane cell surface isoform; alternatively spliced"
/codon_start=1
/product="immunoglobulin superfamily receptor
translocation associated protein 2c"
/protein_id="AAK31327.1"
/translation="MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTC
KGFRFYSPQKTKWYHRYLGKEILRETPDNILEVQESGEYRCQAQGSPLSSPVHLDFSS
ASLILQAPLSVFEGDSVVLRCRAKAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKD
NGAYRCTGYKESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLE
RSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYWCKAATMPHSVISDSPRS
WIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVR
CERGASISFSLTTENSGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIF
EGAKVTLHCEAQRGSLPILYQFHHEDAALERRSANSAGGVAISFSLTAEHSGNYYCTA
DNGFGPQRSKAVSLSITVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFY
HEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGFGPQRSEVVSLFVTVPVSRP
ILTLRVPRAQAVVGDLLELHCEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSL
TAEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFRAPRAQAVVGDLLELHCEA
LRGSSPILYWFYHEDVTLGKISAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEM
VTLKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPLILYRFFHEDVTLGNRSS
PSGGASLNLSLTAEHSGNYSCEADNGLGAQRSETVTLYITGLTANRSGPFATGVAGGL
LSIAGLAAGALLLYCWLSRKAGRKPASDPARSPSDSDSQEPTYHNVPAWEELQPVYTN
ANPRGENVVYSEVRIIQEKKKHAVASDPRHLRNKGSPIIYSEVKVASTPVSGSLFLAS
SAPHR"
BASE COUNT 1263 a 1458 c 1312 g 1288 t
ORIGIN
1 gtgcagtgtc ctgactgtaa gatcaagtcc aaacctgttt tggaattgag gaaacttctc
61 ttttgatctc agcccttggt ggtccaggtc ttcatgctgc tgtgggtgat attactggtc
121 ctggctcctg tcagtggaca gtttgcaagg acacccaggc ccattatttt cctccagcct
181 ccatggacca cagtcttcca aggagagaga gtgaccctca cttgcaaggg atttcgcttc
241 tactcaccac agaaaacaaa atggtaccat cggtaccttg ggaaagaaat actaagagaa
301 accccagaca atatccttga ggttcaggaa tctggagagt acagatgcca ggcccagggc
361 tcccctctca gtagccctgt gcacttggat ttttcttcag cttcgctgat cctgcaagct
421 ccactttctg tgtttgaagg agactctgtg gttctgaggt gccgggcaaa ggcggaagta
481 acactgaata atactattta caagaatgat aatgtcctgg cattccttaa taaaagaact
541 gacttccata ttcctcatgc atgtctcaag gacaatggtg catatcgctg tactggatat
601 aaggaaagtt gttgccctgt ttcttccaat acagtcaaaa tccaagtcca agagccattt
661 acacgtccag tgctgagagc cagctccttc cagcccatca gcgggaaccc agtgaccctg
721 acctgtgaga cccagctctc tctagagagg tcagatgtcc cgctccggtt ccgcttcttc
781 agagatgacc agaccctggg attaggctgg agtctctccc cgaatttcca gattactgcc
841 atgtggagta aagattcagg gttctactgg tgtaaggcag caacaatgcc tcacagcgtc
901 atatctgaca gcccgagatc ctggatacag gtgcagatcc ctgcatctca tcctgtcctc
961 actctcagcc ctgaaaaggc tctgaatttt gagggaacca aggtgacact tcactgtgaa
1021 acccaggaag attctctgcg cactttgtac aggttttatc atgagggtgt ccccctgagg
1081 cacaagtcag tccgctgtga aaggggagca tccatcagct tctcactgac tacagagaat
1141 tcagggaact actactgcac agctgacaat ggccttggcg ccaagcccag taaggctgtg
1201 agcctctcag tcactgttcc cgtgtctcat cctgtcctca acctcagctc tcctgaggac
1261 ctgatttttg agggagccaa ggtgacactt cactgtgaag cccagagagg ttcactcccc
1321 atcctgtacc agtttcatca tgaggatgct gccctggagc gtaggtcggc caactctgca
1381 ggaggagtgg ccatcagctt ctctctgact gcagagcatt cagggaacta ctactgcaca
1441 gctgacaatg gctttggccc ccagcgcagt aaggcggtga gcctctccat cactgtccct
1501 gtgtctcatc ctgtcctcac cctcagctct gctgaggccc tgacttttga aggagccact
1561 gtgacacttc actgtgaagt ccagagaggt tccccacaaa tcctatacca gttttatcat
1621 gaggacatgc ccctgtggag cagctcaaca ccctctgtgg gaagagtgtc cttcagcttc
1681 tctctgactg aaggacattc agggaattac tactgcacag ctgacaatgg ctttggtccc
1741 cagcgcagtg aagtggtgag cctttttgtc actgttccag tgtctcgccc catcctcacc
1801 ctcagggttc ccagggccca ggctgtggtg ggggacctgc tggagcttca ctgtgaggcc
1861 ccgagaggct ctcccccaat cctgtactgg ttttatcatg aggatgtcac cctggggagc
1921 agctcagccc cctctggagg agaagcttct ttcaacctct ctctgactgc agaacattct
1981 ggaaactact catgtgaggc caacaatggc ctagtggccc agcacagtga cacaatatca
2041 ctcagtgtta tagttccagt atctcgtccc atcctcacct tcagggctcc cagggcccag
2101 gctgtggtgg gggacctgct ggagcttcac tgtgaggccc tgagaggctc ctccccaatc
2161 ctgtactggt tttatcatga agatgtcacc ctgggtaaga tctcagcccc ctctggagga
2221 ggggcctcct tcaacctctc tctgactaca gaacattctg gaatctactc ctgtgaggca
2281 gacaatggtc tggaggccca gcgcagtgag atggtgacac tgaaagttgc agttccggtg
2341 tctcgcccgg tcctcaccct cagggctccc gggacccatg ctgcggtggg ggacctgctg
2401 gagcttcact gtgaggccct gagaggctct cccctgatcc tgtaccggtt ttttcatgag
2461 gatgtcaccc taggaaatag gtcgtccccc tctggaggag cgtccttaaa cctctctctg
2521 actgcagagc actctggaaa ctactcctgt gaggccgaca atggcctcgg ggcccagcgc
2581 agtgagacag tgacacttta tatcacaggg ctgaccgcga acagaagtgg cccttttgcc
2641 acaggagtcg ccgggggcct gctcagcata gcaggccttg ctgcgggggc actgctgctc
2701 tactgctggc tctcgagaaa agcagggaga aagcctgcct ctgaccccgc caggagccct
2761 tcagactcgg actcccaaga gcccacctat cacaatgtac cagcctggga agagctgcaa
2821 ccagtgtaca ctaatgcaaa tcctagagga gaaaatgtgg tttactcaga agtacggatc
2881 atccaagaga aaaagaaaca tgcagtggcc tctgacccca ggcatctcag gaacaagggt
2941 tcccctatca tctactctga agttaaggtg gcgtcaaccc cggtttccgg atccctgttc
3001 ttggcttcct cagctcctca cagatgagtc cacacgtctc tccaactgct gtttcagcct
3061 ctgcacccca aagttcccct tgggggagaa gcagcattga agtgggaaga tttaggctgc
3121 cccagaccat atctactggc ctttgtttca catgtcctca ttctcagtct gaccagaatg
3181 cagggccctg ctggactgtc acctgtttcc cagttaaagc cctgactggc aggtttttta
3241 atccagtggc aaggtgctcc cactccaggg cccagcacat ctcctggatt ccttagtggg
3301 cttcagctgt ggttgctgtt ctgagtactg ctctcatcac acccccacag agggggtctt
3361 accacacaaa gggagagtgg gccttcagga gatgccgggc tggcctaaca gctcaggtgc
3421 tcctaaactc cgacacagag ttcctgcttt gggtggatgc atttctcaat tgtcatcagc
3481 ctggtggggc tactgcagtg tgctgccaaa tgggacagca cacagcctgt gcacatggga
3541 catgtgatgg gtctccccac gggggctgca tttcacactc ctccacctgt ctcaaactct
3601 aaggtcggca cttgacacca aggtaacttc tctcctgctc atgtgtcagt gtctacctgc
3661 ccaagtaagt ggctttcata caccaagtcc cgaagttctt cccatcctaa cagaagtaac
3721 ccagcaagtc aaggccagga ggaccagggg tgcagacaga acacatactg gaacacagga
3781 ggtgctcaat tactatttga ctgactgact gaatgaatga atgaatgagg aagaaaactg
3841 tgggtaatca aactggcata aaatccagtg cactccctag gaaatccggg aggtattctg
3901 gcttcctaag aaacaacgga agagaaggag cttggatgaa gaaactgttc agcaagaaga
3961 agggcttctt cacactttta tgtgcttgtg gatcacctga ggatctgtga aaatacagat
4021 actgattcag tgggtctgtg tagagcctga gactgccatt ctaacatgtt cccaggggat
4081 gctgatgctg ctggccctgg gactgcactg catgcatgtg aagccctata ggtctcagca
4141 gaggcccatg gagagggaat gtgtggctct ggctgcccag ggcccaactc ggttcacacg
4201 gatcgtgctg ctccctggcc agcctttggc cacagcacca ccagctgctg ttgctgagag
4261 agcttcttct ctgtgacatg ttggctttca tcagccaccc tgggaagcgg aaagtagctg
4321 ccactatctt tgtttcccca cctcaggcct cacactttcc catgaaaagg gtgaatgtat
4381 ataacctgag ccctctccat tcagagttgt tctcccatct ctgagcaatg ggatgttctg
4441 ttccgctttt atgatatcca tcacatctta tcttgatctt tgctcccagt ggattgtaca
4501 gtgatgactt ttaagcccca cggccctgaa ataaaatcct tccaagggca ttggaagctc
4561 actccacctg aaccatggct tttcatgctt ccaagtgtca gggccttgcc cagatagaca
4621 gggctgactc tgctgcccca acctttcaag gaggaaacca gacacctgag acaggagcct
4681 gtatgcagcc cagtgcagcc ttgcagagga caaggctgga ggcatttgtc atcactacag
4741 atatgcaact aaaatagacg tggagcaaga gaaatgcatt cccaccgagg ccgctttttt
4801 aggcctagtt gaaagtcaag aaggacagca gcaagcatag gctcaggatt aaagaaaaaa
4861 atctgctcac agtctgttct ggaggtcaca tcaccaacaa agctcacgcc ctatgcagtt
4921 ctgagaaggt ggaggcacca ggctcaaaag aggaaattta gaatttctca ttgggagagt
4981 aaggtacccc catcccagaa tgataactgc acagtggcag aacaaactcc accctaatgt
5041 gggtggaccc catccagtct gttgaaggcc tgaatgtaac aaaagggctt attcttcctc
5101 aagtaagggg gaactcctgc tttgggctgg gacataagtt tttctgcttt cagacgcaaa
5161 ctgaaaaatg gctcttcttg ggtcttgagc ttgctggcat atggactgaa agaaactatg
5221 ctattggatc tcctggatct ccagcttgct gactgcagat cttgagatat gtcagcctct
5281 acagtcacaa gagctaattc attctaataa accaatcttt c
//